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G_LAU.ppt
G_LAU.ppt

... prior course of treatment with PegIFN-α and/or RBV  Re-treatment with BOC/TVR + PegIFN-α and/or RBV • Re-treatment with TVR/PegIFN-α /RBV for prior null responders to standard PegIFN-α/RBV therapy • Response-guided therapy using BOC/TVR based treatments cannot be recommended for ...
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Chow, Lu-Ping 周綠蘋 - 臺大基因體醫學研究中心
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... 3. Lin YF, Chen CY, Tsai MH, Wu MS, Wang YC, Chuang EY, Lin JT, Yang PC, and Chow LP*. Duodenal ulcer-related antigens from Helicobacter pylori: immunoproteome and protein microarray approaches. Molecular & Cellular Proteomic s 2007, 6(6) : 1018-26. 4. Chiu LL, Lee KL, Lin YF, Chu CY, Su SN, and Cho ...
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Biochemical and Molecular Genetics of Human Disease
Biochemical and Molecular Genetics of Human Disease

... parents do not exhibit the anomaly and direct transmission from parent to child is very rare” – In 8 of 17 families, parents were first cousins ...
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Pharmacometabolomics

Pharmacometabolomics, also known as pharmacometabonomics, is a field which stems from metabolomics, the quantification and analysis of metabolites produced by the body. It refers to the direct measurement of metabolites in an individual’s bodily fluids, in order to predict or evaluate the metabolism of pharmaceutical compounds, and to better understand the pharmacokinetic profile of a drug. Alternatively, pharmacometabolomics can be applied to measure metabolite levels following the administration of a pharmaceutical compound, in order to monitor the effects of the compound on certain metabolic pathways(pharmacodynamics). This provides detailed mapping of drug effects on metabolism and the pathways that are implicated in mechanism of variation of response to treatment. In addition, the metabolic profile of an individual at baseline (metabotype) provides information about how individuals respond to treatment and highlights heterogeneity within a disease state. All three approaches require the quantification of metabolites found in bodily fluids and tissue, such as blood or urine, and can be used in the assessment of pharmaceutical treatment options for numerous disease states.
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