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HIV -1 Replication Rate - Mathematical and Theoretical Biology
HIV -1 Replication Rate - Mathematical and Theoretical Biology

... Researchers have been trying to understand why the human immunodeficiency virus (HIV) leads to the collapse of the immune system. One hypothesis is that HIV destroys target cells that have CD4 receptors. These target cells, or white blood cells, are crucial to the immune system. Once infected, a tar ...
viral hemorrhagic fevers - the County of Santa Clara
viral hemorrhagic fevers - the County of Santa Clara

... mosquitoes and ticks. Under natural conditions, these diseases are relatively rare in the United States. There are a number of distinct viruses that cause hemorrhagic fevers such as Ebola, Lassa and Marburg. ...
Oral, Ocular, Nail and Hair Changes in HIV Shilpa K and Lakshmi DV
Oral, Ocular, Nail and Hair Changes in HIV Shilpa K and Lakshmi DV

... syndrome (AIDS).The periodontal conditions most closely associated with HIV infection include linear gingival erythema and necrotizing gingival and periodontal diseases. These conditions are declining, in part because of antiretroviral therapy, dental and healthcare practitioners will need to diagn ...
Dromedaries as possible reservoir of some infectious diseases
Dromedaries as possible reservoir of some infectious diseases

... • RVFV => IgG, c-ELISA • RVFV => qRT-PCR • PPRV => c-ELISA • WNV => c-ELISA ...
Nororvirus Fact Sheet
Nororvirus Fact Sheet

... Infected individuals usually experience sudden onset of nausea, vomiting and watery diarrhea that lasts about one to three days. Other symptoms may include fever and stomach cramps. Severe illness or hospitalization is uncommon. Dehydration is the most common complication, especially among young chi ...
Central nervous system infections
Central nervous system infections

... carried in the throats of many healthy individuals Invasion of the blood and meninges is a rare event, but is more common:  in the very young (<2 years of age),  in the elderly, in those with sickle cell disease, in debilitated ...
Editable Lecture PowerPoint
Editable Lecture PowerPoint

... Spreads through direct contact with bodily fluids of infected people and animals, as well as from contaminated surfaces. ...
Psittacid Herpesvirus 1 and Infectious Laryngotracheitis Virus
Psittacid Herpesvirus 1 and Infectious Laryngotracheitis Virus

... targets hepatocytes and lymphocytes and slowly forms syncytial plaques in tissue culture. It has been previously classified both as a betaherpesvirus and as a gammaherpesvirus (31). Although there is limited PsHV-1 sequence available, phylogenetic studies based on the sequences of the PsHV-1 UL16 an ...
What to do if you suspect Parvo virus infection.
What to do if you suspect Parvo virus infection.

... Parvo is a highly infectious and highly contagious virus with several strains that are most often fatal in unprotected puppies. Some breeds of dogs are more predisposed to Parvo (Rottweilers, Staffordshire terriers, Dobermans) but no breed is resistant to this disease. Once exposed to the virus ther ...
Emerging and Re-emerging Infectious Diseases
Emerging and Re-emerging Infectious Diseases

... particles by EM.34 These viruses are now classified within a separate family, Astroviridae.35 They carry a genome of single stranded RNA of positive polarity and 6.8 kb size, possessing three open reading frames (ORFs), of which the second encodes the single capsid protein.36 So far, eight different ...
Hepatitis B Virus Infection — Natural History and
Hepatitis B Virus Infection — Natural History and

... with the use of the newly made first DNA strand as a template.25,27,29 Some cores bearing the mature genome are transported back to the nucleus, where their newly minted DNA genomes can be converted to cccDNA to maintain a stable intranuclear pool of transcriptional templates.26 Most cores, however, ...
Rapid Detection of Infectious Pancreatic Necrosis Virus (IPNV) by
Rapid Detection of Infectious Pancreatic Necrosis Virus (IPNV) by

... An undiluted cell culture harvest of IPNV serotype Sp showing complete c.p.e, was tested by the ELISA technique and a strong positive result (A,o5 > 2) was obtained, whereas a control cell harvest produced a minimal A4o5 reading. An experiment was then done to determine whether virus antigen could b ...
Risk factors associated with HIV infection among young persons
Risk factors associated with HIV infection among young persons

... whose age at first sexual intercourse was less than 14 years are significantly associated with 2.696 times more risk of HIV infection relative to their peers whose age at first sexual intercourse was 20 – 24 years (p ¼ 0.000). Young persons aged 15 – 24 years with two or more sex partners in the past 1 ...
RNA genomes
RNA genomes

... • Advises on and recommends specific strategies for the efficient and effective oversight of federally conducted or supported dual use biological research, taking into consideration national security concerns and the needs of the ...
enteric viruses in new zealand drinking-water sources
enteric viruses in new zealand drinking-water sources

... Indicator organisms ideally need to f ulfil several criteria, including being present when the pathogen is present, not multiplying in the environment, having a constant ratio between itself and the pathogen(s) or the risk of waterborne infection, being present at greater concentrations than the pat ...
Quantifying relative within-host replication fitness in influenza virus
Quantifying relative within-host replication fitness in influenza virus

... influenza viruses, relative to contemporary circulating viruses, provides valuable information to complement existing efforts in the surveillance of drug-resistance. We have previously developed a co-infection based method for the assessment of the relative in vivo fitness of two competing viruses. We ...
Staggering Disease in a Cat - The Journal of Applied Research in
Staggering Disease in a Cat - The Journal of Applied Research in

... and then centrifugally towards the peripheral nervous system, where it infects the nerves of different organs and can then be excreted by natural secretions.2,35,38 However, vector(s) or reservoir(s) for this virus have not yet been identified. Likewise, the common pathways of intraspecific and inte ...
Personal Service Establishments: Looking at Infections Risks
Personal Service Establishments: Looking at Infections Risks

... are at greatest risk but may be unaware of their risks13,14 – Infections have been reported among individuals with no known heart conditions15,16 ...
osha`s bloodborne pathogens standard 29 cfr part 1910.1030
osha`s bloodborne pathogens standard 29 cfr part 1910.1030

... In the health care setting, workers have been infected with HIV after being stuck with needles containing HIV-infected blood or, less frequently, after infected blood gets into a worker’s open cut or a mucous membrane (for example, the eyes or inside of the nose). There has been only one instance of ...
What do you know about the Zika virus? How could this possibly
What do you know about the Zika virus? How could this possibly

... and microcephaly, a neurological disorder that results in babies being born with abnormally small heads. This causes severe developmental issues and sometimes death. Since November, Brazil has seen 4,180 cases of microcephaly in babies born to women who were infected with Zika during their pregnanci ...
Infection Control Update
Infection Control Update

... of September 11, 2001. Unfortunately, some of them got bad news after the blood bank screened their blood. For every thousand people who donated blood, two of them were notified that they have hepatitis C. ...
Herpesviruses_Gersho..
Herpesviruses_Gersho..

... form at the time of diagnosis). There are no symptoms other than the skin rash (grouped vesicles). There is an excellent prognosis with early therapy, which keeps virus from spreading. It is possible to diagnose these infections easily because the virus produces the skin lesions from which it can be ...
Avian Pathology The replication characteristics of infectious
Avian Pathology The replication characteristics of infectious

... the severe form, additional signs are gasping, bloody mucus expectoration, dyspnoea and death due to asphyxia (Fuchs et al., 2007). ILT has an economic impact by causing severe ...
A sandwich ELISA to detect VHSV and IPNV in turbot | SpringerLink
A sandwich ELISA to detect VHSV and IPNV in turbot | SpringerLink

... (Domfnguez et al., I991) serotypes. Furthermore, these proteins are a major component in both the complete virus and infected cells (Basurco et al., 1991). First attempts to produce ELISA assays for the detection of VHSV with sufficiently high sensitivity were unsuccessful, apparently because the ti ...
Discontinuous Sequence Change of Human Immunodeficiency
Discontinuous Sequence Change of Human Immunodeficiency

... HIV sequences were amplified by polymerase chain reaction to allow analysis in the V3, V4, and V5 hypervariable regions of gpl20. Rapid sequence change, consisting of regular replacements by a succession of distinct viral populations, was found in both plasma virus and PBMC provirus populations. Sig ...
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HIV



The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and acquired immunodeficiency syndrome (AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.HIV infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells. HIV infection leads to low levels of CD4+ T cells through a number of mechanisms, including apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections.
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