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FDA Regulation of Biologics
FDA Regulation of Biologics

... Stable aerosol Virus Easy to Produce Infectious at low doses Human to human transmission 10 to 12 day incubation period High mortality rate (30%) ...
Avian influenza A H5N1 infection on human cellular microRNA
Avian influenza A H5N1 infection on human cellular microRNA

... in a wide spectrum of biological processes. MiRNA is one of the major gene regulatory families in eukaryotic cells.4,5 However, the functions of most of the identified miRNAs remains unknown. The miRNA pathway exists in viral species, indicating that the host miRNAs may also have a direct or indirec ...
test - Scioly.org
test - Scioly.org

... 15. A number of passengers on a cruise ship from Puerto Rico to the Panama Canal have recently developed a gastrointestinal illness compatible with norovirus (formerly called Norwalk-like virus). Testing for norovirus is not readily available in any nearby island, and the test takes several days eve ...
have been linked to acute bronchitis. People at - Home Planet
have been linked to acute bronchitis. People at - Home Planet

... Bronchitis is an inflammation of the bronchial tubes, the part of the respiratory system that leads into the lungs. Acute bronchitis has a sudden onset and usually appears after a respiratory infection, such as a cold, and can be caused by either a virus bacteria. The infection inflames the bronchi ...
n.l. carreck, b.v. b..
n.l. carreck, b.v. b..

... that secondary infections by other pathogens might explain the observed variation in the effect of mite parasitism. Work in Germany and elsewhere on mainland Europe in the early 1980s (BALL, 1985; BALL and ALLEN, 1988) showed that the primary cause of mortality in severely infested colonies was acut ...
Slide 1
Slide 1

...  Case reports of transmission from blood splash to eye; one from exposure to non-intact skin  Prevalence 1-2% among health care workers  Lower than adults in the general population  10 times lower than for HBV infection ...
malignant catarrhal fever
malignant catarrhal fever

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COMMON INFECTIOUS DISEASES IN CHILDREN
COMMON INFECTIOUS DISEASES IN CHILDREN

... Chickenpox is a common infectious disease. It is caused by a virus called varicella zoster and is spread by sneezing and coughing or direct contact with broken chickenpox blisters. It is much more severe in adults than in children and can be a particular problem in pregnancy. Shingles (also known as ...
childhood diseases - Leeds, Grenville and Lanark District Health Unit
childhood diseases - Leeds, Grenville and Lanark District Health Unit

... exposure), small white spots on the • incubation period *7-18 days from exposure to or measles infection should be excluded for inside of the mouth and throat onset of fever ...
CHILDHOOD DISEASES
CHILDHOOD DISEASES

... exposure), small white spots on the • incubation period *7-18 days from exposure to or measles infection should be excluded for inside of the mouth and throat onset of fever ...
Pathogen and Outbreak Cards - University of Colorado Denver
Pathogen and Outbreak Cards - University of Colorado Denver

... Shigellosis  is  an  infectious  disease  caused  byShigella.   The  Shigella  germ  is  a  family  of  bacteria  that  can  cause  diarrhea   in  humans.  People  with  shigellosis  shed  the  bacteria  in  their   feces.  The  bacteria ...
Viral haemorrhagic fevers in South Africa
Viral haemorrhagic fevers in South Africa

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Rabies Presentation
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Pathogens in the Environment
Pathogens in the Environment

... • Harmless to humans and other animals. • Numbers in water (food, etc.) are associated with risks of enteric illness in consumers (dose-response relationship). ...
Zoonotic aspects of vector-borne infections
Zoonotic aspects of vector-borne infections

... epizootic outbreaks affecting mainly domestic ruminants (cattle, sheep, goats, buffalo), causing abortions and high mortality rates in young animals. Before 1977, Rift Valley fever was confined to sub-Saharan Africa, where it mainly caused epizootic outbreaks; human cases were rare and not serious. ...
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... All viruses are intracellular pathogens therefore cell-mediated immunity plays an important role in recovery. The role of antibody is dependent on how virus replicates and spreads to uninfected cells. There are three ways a virus can spread… 1. EXTRACELLULAR (lytic viruses) release virion into extra ...
In Situ Capture RT-qPCR: A New Simple and Sensitive Method to
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... gastroenteritis. In this study, we applied a novel viral receptor mediated in situ capture RT-qPCR (ISC-RT-qPCR) to detect HuNoVs in oysters and compared with the traditional RT-qPCR method. Ten HuNoVs RT-PCR positive and 5 negative clinical samples from gastroenteritis patients were used to compare ...
Ebola Information - The College at Brockport
Ebola Information - The College at Brockport

... the affected areas. The College has reached out to members of the student body with known ties to countries affected by Ebola. Fortunately, none of our students have had known exposure to the Ebola virus. Supportive hospital care can significantly increase survival, but there are no medications that ...
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... In neonates with isolated skin or mucosal disease, progressive or more serious forms of disease frequently follow within 7 to 10 days if left untreated. Infection is particularly dangerous in premature infants. ...
Frequently Asked Questions
Frequently Asked Questions

... Infection occurs from direct contact through broken skin or mucous membranes with the blood, or other bodily fluids or secretions (stool, urine, saliva, semen) of infected people. Infection can also occur if broken skin or mucous membranes of a healthy person come into contact with environments that ...
Atieh et al. - ZIKAlliance
Atieh et al. - ZIKAlliance

... requires effective reverse genetics tools. In the current study, using the bacterium-free ‘Infectious Subgenomic Amplicons’ (ISA) method, we generated and made available to the scientific community via the non-profit European Virus Archive collection, two simple and performing reverse genetics syste ...
Sexually Transmitted Infections
Sexually Transmitted Infections

... person when lesions are present • HSV-1 infection can occur on the genitals following oral-genital contact with a person who has a cold sore ...
Bloodborne Pathogens
Bloodborne Pathogens

... Any body fluid visibly contaminated with blood All body fluids when it is difficult or impossible to differentiate between body fluids ...
Understand Seasonal Flu, Human Swine Flu and Hand-foot
Understand Seasonal Flu, Human Swine Flu and Hand-foot

... Human-to-human transmission of swine flu is thought to occur in the same way as seasonal flu is spread among people – mainly through coughing or sneezing. – People may also become infected by touching objects soiled with flu viruses and then touching their mouth, nose or eyes. Infectious Period – It ...
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Norovirus



Norovirus, sometimes known as the winter vomiting bug in the UK, is the most common cause of viral gastroenteritis in humans. It affects people of all ages. The virus is transmitted by fecally contaminated food or water, by person-to-person contact, and via aerosolization of the virus and subsequent contamination of surfaces. The virus affects around 267 million people and causes over 200,000 deaths each year; these deaths are usually in less developed countries and in the very young, elderly and immunosuppressed.Norovirus infection is characterized by nausea, projectile vomiting, malodorous watery diarrhea, abdominal pain, and in some cases, loss of taste. General lethargy, weakness, muscle aches, headache, and low-grade fever may occur. The disease is usually self-limiting, and severe illness is rare. Although having norovirus can be unpleasant, it is not usually dangerous and most who contract it make a full recovery within a couple of days. Norovirus is rapidly inactivated by either sufficient heating or by chlorine-based disinfectants and polyquaternary amines, but the virus is less susceptible to alcohols and detergents.After infection, immunity to norovirus is usually incomplete and temporary, with one publication drawing the conclusion that protective immunity to the same strain of norovirus lasts for six months, but that all such immunity is gone after two years. Outbreaks of norovirus infection often occur in closed or semiclosed communities, such as long-term care facilities, overnight camps, hospitals, schools, prisons, dormitories, and cruise ships, where the infection spreads very rapidly either by person-to-person transmission or through contaminated food. Many norovirus outbreaks have been traced to food that was handled by one infected person.The genus name Norovirus is derived from Norwalk virus, the only species of the genus. The species causes approximately 90% of epidemic nonbacterial outbreaks of gastroenteritis around the world, and may be responsible for 50% of all foodborne outbreaks of gastroenteritis in the United States.
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