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Sept2_Lecture3
Sept2_Lecture3

... •Early in the 1980's, a number of gay and bisexual men developed Kaposi's Sarcoma, which had previously been a rare skin cancer seen primarily in the Mediterranean and Africa. Investigation into these new cases of KS and pneumocystic pneumonia led, in part, to the identification of the Acquired Immu ...
Food Safety and Avian Influenza
Food Safety and Avian Influenza

... Q. Can I get avian influenza from eating poultry or eggs? A. No. Poultry and eggs that are properly prepared and cooked are safe to eat. Proper food safety practices are important every day. In addition to proper processing, proper handling and cooking of poultry provides protection from viruses and ...
viruses - Lisle CUSD 202
viruses - Lisle CUSD 202

... 3. Help rid the world of diseases that have been crippling and killing children for centuries. Immunization allowed us to eradicate smallpox. Today polio is nearly gone, and in the future measles and other diseases will follow. ...
Chapter 6
Chapter 6

... may project from the envelope surface as spikes or peplomers – involved in viral attachment to host cell • e.g., hemagglutinin of influenza virus ...
If Pigs Could Fly, Would They Carry Bird Flu?
If Pigs Could Fly, Would They Carry Bird Flu?

... • Circulates year round;  during flu season • High rates of illness, low death rates in pigs • The 2009 human flu outbreak is a new strain of H1N1 influenza never isolated in swine (origin unknown) • Pigs are very susceptible to infection from humans ...
viruses
viruses

... May integrate its DNA as a provirus (becoming like mini-chromosomes in nucleus) Tends to recur throughout lifetime of infected individual. Often triggered by environmental ...
Emerging Infectious Disease
Emerging Infectious Disease

... and/or significant economic losses. Perhaps the most significant diseases which arise as new variants or ‘reassortants’ are new influenza A strains, especially those with pandemic potential. Thus the Spanish flu pandemic in 1918-19 resulted in over 40 million deaths, and the estimated global cost of ...
Deoxyribonucleic Acid
Deoxyribonucleic Acid

... consisting of human, avian, and swine influenzas Virus strains 90% identical to H1N1 have been circulating in swine for approximately 10 years Combination of viral strains thought to have arisen when live pigs were transported between North America and Eurasia Source: http://www.gate2biotech.com/ori ...
Prions
Prions

... • Readings question #4: what is the virus that is responsible for this disease? How is it spread? • Chickenpox and Shingles: – Shingles rarely occurs in people under the age of ...
Media Release
Media Release

... economics, as well as for other diseases that affect humans and agricultural animals. "The challenge for the future is to identify other vaccines that also might allow more-virulent versions of a virus to survive and possibly to become even more harmful," said Andrew Read, an author of the paper des ...
Micro organisms
Micro organisms

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Identification of Viral Genes Essential for Replication of Murine
Identification of Viral Genes Essential for Replication of Murine

... gammaherpesvirus-68 (MHV-68 or HV-68) has recently emerged as a small animal model system for the study of human gammaherpesvirus pathogenesis and host-virus interactions. We have established a random transposon-inserted mutant library of MHV-68 for identification of genes required for virus replic ...
Persistent infection
Persistent infection

... some viral particles. It is acquired during viral maturation by a budding process through a cellular membrane. Virion – The complete viral particle, which in some viruses may be identical with nucleocapsid. In more complex virions, this includes the nucleocapsid plus a surrounding envelope. The vir ...
Subviral Entities and Viral Evolution - Cal State LA
Subviral Entities and Viral Evolution - Cal State LA

... within true cells when they in turn evolved.  This theory is based on current ideas that suggest that the first genetic material to develop was RNA.  The theory does not consider how DNA viruses arose ...
Viruses
Viruses

... • Through the 1800s, many scientists discovered that something smaller than bacteria could cause disease and they called it virion (Latin word- poison). • In the 1930s, after the invention of electron microscopes, viruses finally could be seen. • The first photographs of viruses were obtained in 194 ...
Visible Viruses - Yale Peabody Museum of Natural History
Visible Viruses - Yale Peabody Museum of Natural History

... to the empty plasma membrane and inject DNA. This “ghost DNA” is visible in the empty space. ...
Chapter 17 2015 - Franklin College
Chapter 17 2015 - Franklin College

... gained the ability to move between cells; b.The regressive, or reduction, hypothesis asserts that viruses are remnants of cellular organisms; c. The virus-first hypothesis states that viruses coevolved with their current cellular hosts. ...
Chapter 19 Teacher 10ded
Chapter 19 Teacher 10ded

... 1. 1883 Adolf Mayer, a German scientist was seeking the cause of tobacco mosaic disease. Because he could not find the microbe in the infectious sap, he concluded that the “bacteria” was unusually small. Fig. 19.2 2. 1935 an American scientist Wendell Stanley crystallized the infectious particle now ...
Viruses - Houston ISD
Viruses - Houston ISD

... proteins on their surfaces that allow them to infect their host cells. Some viruses do not change very often, so the vaccines for these viruses remain effective- smallpox, polio, and measles are all easily prevented using vaccines. However, some viruses have surface proteins that mutate (change) oft ...
Human influenza A H5N1 virus related to a highly
Human influenza A H5N1 virus related to a highly

... from Hong Kong.32 Preliminary sequencing results of some of the more recent human virus isolates indicate that they are similar to, but distinguishable from, the first isolate. All genes are of avian origin (WHO press release, Dec 17, 1997), suggesting multiple independent transmissions from infecte ...
Mike Shaw - Institute for People and Technology
Mike Shaw - Institute for People and Technology

... Adaptation or Virulence • NA stalk deletion aa 69-73 characteristic of poultry adaptation • M1 protein: N30D and T215A – increased virulence in mice • PB2: • 89V – enhanced polymerase activity and increased virulence in mice • 627K - enhanced polymerase activity and increased virulence in mice (most ...
PowerPoint 演示文稿
PowerPoint 演示文稿

... Antigenic Shift involving entire viral single-stranded RNA's incorporation and increase in infectivity of newly arising influenza strain. Antigenic Drift involves point mutations in Hemagglutinin or Neuraminidase allowing for viral escape from antibody inhibition. ...
Anti-Infectious Pancreatic Necrosis Virus (IPNV) VP2 protein. IgG
Anti-Infectious Pancreatic Necrosis Virus (IPNV) VP2 protein. IgG

... autocatalytically cleaved by the endoprotease VP4 to release the structural proteins pVP2 (62 kDa) and VP3. pVP2 is processed during virus maturation into VP2 (54 kDa) constituting the outer capsid component. IPNV is responsible for infectious pancreatic necrosis, a contagious fish disease character ...
病毒概述
病毒概述

... cell membrane and viral envelope The enveloped viruses 包膜病毒 ...
Lecture 18
Lecture 18

... carbohydrates, and proteins (basically similar in structure to an enhanced plasma membrane, but with a DIFFERENT FUNCTION!) ...
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Influenza A virus



Influenza A virus causes influenza in birds and some mammals, and is the only species of influenza virus A. Influenza virus A is a genus of the Orthomyxoviridae family of viruses. Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally, viruses are transmitted from wild aquatic birds to domestic poultry, and this may cause an outbreak or give rise to human influenza pandemics.Influenza A viruses are negative-sense, single-stranded, segmented RNA viruses.The several subtypes are labeled according to an H number (for the type of hemagglutinin) and an N number (for the type of neuraminidase). There are 18 different known H antigens (H1 to H18) and 11 different known N antigens (N1 to N11). H17 was isolated from fruit bats in 2012. H18N11 was discovered in a Peruvian bat in 2013.Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.A filtered and purified influenza A vaccine for humans has been developed, and many countries have stockpiled it to allow a quick administration to the population in the event of an avian influenza pandemic. Avian influenza is sometimes called avian flu, and colloquially, bird flu. In 2011, researchers reported the discovery of an antibody effective against all types of the influenza A virus.
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