The Evolution of the Myofibroblast Concept: a Key Cell for
... Myofibroblast contraction and fibrosis The role of the fibroblast in determining organ shape during embryonic development has been suspected for many years and is presently more and more accepted 14. The most plausible mechanism of this morphogenetic action is extracellular matrix shape remodeling t ...
... Myofibroblast contraction and fibrosis The role of the fibroblast in determining organ shape during embryonic development has been suspected for many years and is presently more and more accepted 14. The most plausible mechanism of this morphogenetic action is extracellular matrix shape remodeling t ...
Nuclear Envelope Breakdown Proceeds by
... 2000), and together with in vivo observations suggest that the nuclear periphery is a highly crosslinked and stable protein network (Daigle et al., 2001). In dividing cells, this network is abolished during NE breakdown (NEBD), which defines the transition from prophase to prometaphase in the cell d ...
... 2000), and together with in vivo observations suggest that the nuclear periphery is a highly crosslinked and stable protein network (Daigle et al., 2001). In dividing cells, this network is abolished during NE breakdown (NEBD), which defines the transition from prophase to prometaphase in the cell d ...
Stem Cells
... in dose of these same genes that play important roles in endocytic sorting. Specifically, Alzheimers disease and Parkinsons disease can both be caused by duplication of a single gene such as amyloid precursor protein or alpha-synuclein, i.e., an increase of two copies to three copies or a 50% increa ...
... in dose of these same genes that play important roles in endocytic sorting. Specifically, Alzheimers disease and Parkinsons disease can both be caused by duplication of a single gene such as amyloid precursor protein or alpha-synuclein, i.e., an increase of two copies to three copies or a 50% increa ...
Endomembrane trafficking protein SEC24A regulates cell size
... GDP with GTP on the small GTPase SAR1, which increases the membrane affinity of SAR1. The ER membrane bound SAR1 subsequently brings the SEC23/24 subunits to form the pre-budding complex and eventually SEC13/31 are recruited to increase rigidity of the COPII vesicle coat (Nakano and Muramatsu, 1989; ...
... GDP with GTP on the small GTPase SAR1, which increases the membrane affinity of SAR1. The ER membrane bound SAR1 subsequently brings the SEC23/24 subunits to form the pre-budding complex and eventually SEC13/31 are recruited to increase rigidity of the COPII vesicle coat (Nakano and Muramatsu, 1989; ...
Endomembrane trafficking protein SEC24A regulates cell size
... mechanisms of plants cytokinesis (Sylvester, 2000; Jurgens, 2005). In many eukaryotes other than plants, cytokinesis is accomplished by contraction of the cleavage furrow at the division plane. In contrast, cytokinesis in plants requires de novo secretion of vesicles to the division plane, after for ...
... mechanisms of plants cytokinesis (Sylvester, 2000; Jurgens, 2005). In many eukaryotes other than plants, cytokinesis is accomplished by contraction of the cleavage furrow at the division plane. In contrast, cytokinesis in plants requires de novo secretion of vesicles to the division plane, after for ...
Programmed cell death in plant development
... Plants live very economically. When the cell wall itself is able to accomplish a specific function, the protoplast is eliminated. Sclerenchyma cells are dead because thick cell walls perform the mechanical function. Phellem, commonly known as cork, is constituted of characteristic cells with a thick ...
... Plants live very economically. When the cell wall itself is able to accomplish a specific function, the protoplast is eliminated. Sclerenchyma cells are dead because thick cell walls perform the mechanical function. Phellem, commonly known as cork, is constituted of characteristic cells with a thick ...
Chapter 3: Movement Of Substances Across the Substances
... P2-No energy is produced P3-Contractile vacuole will not work/pump P4-Excess water cannot be expelled ...
... P2-No energy is produced P3-Contractile vacuole will not work/pump P4-Excess water cannot be expelled ...
YEAR 11 BIOLOGY - Matrix Education
... Cells contain hereditary information that is passed from cell to cell during cell division. All basic chemical and physiological processes are carried out inside cells. All cells are basically the same in chemical ...
... Cells contain hereditary information that is passed from cell to cell during cell division. All basic chemical and physiological processes are carried out inside cells. All cells are basically the same in chemical ...
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... reports of single cases or small series of patient with BCCs on sites other than the scrotum, a significant relationship between HPV and BCCs in the general population has yet to be established. ...
... reports of single cases or small series of patient with BCCs on sites other than the scrotum, a significant relationship between HPV and BCCs in the general population has yet to be established. ...
Metaplastic carcinoma of the breast: A clinicopathological review
... spindle cell carcinomas to arise from pre-existing lesions, including Papillomas, Complex sclerosing lesions and nipple adenomas (3,4). Metaplastic or Spindle cell carcinoma arising from such lesions can show a varying degree of malignancy, ranging fromlow to high grade. This type of lesion should a ...
... spindle cell carcinomas to arise from pre-existing lesions, including Papillomas, Complex sclerosing lesions and nipple adenomas (3,4). Metaplastic or Spindle cell carcinoma arising from such lesions can show a varying degree of malignancy, ranging fromlow to high grade. This type of lesion should a ...
Macroscopic stiffening of embryonic tissues via
... cell rearrangement during gastrulation is regulated by the planar cell polarity (PCP) pathway. Cell or tissue response to chemotactic signals or activation of the PCP pathway depends both on specific details of the molecular programs, as well as on the mechanical context in which they play out (Davi ...
... cell rearrangement during gastrulation is regulated by the planar cell polarity (PCP) pathway. Cell or tissue response to chemotactic signals or activation of the PCP pathway depends both on specific details of the molecular programs, as well as on the mechanical context in which they play out (Davi ...
Osteocytes are dynamic, not passive cells in their response to strain
... LF Bonewald, J Feng, SE Harris, JX Jiang, S Kotha, N Lane, D Nicolella, E Sprague The matrix producing osteoblast is highly metabolically active compared to the osteocyte. This is probably due to the fact that osteoblasts exist as matrix producing cells for only days or a few weeks and must generate ...
... LF Bonewald, J Feng, SE Harris, JX Jiang, S Kotha, N Lane, D Nicolella, E Sprague The matrix producing osteoblast is highly metabolically active compared to the osteocyte. This is probably due to the fact that osteoblasts exist as matrix producing cells for only days or a few weeks and must generate ...
Quantitative analysis of yeast internal architecture using soft X‐ray
... size before the process of cell division is initiated, and that the cells continue to grow as the cycle proceeds (Calvert and Dawes, 1984; Goranov et al., 2009; Mitchison, 1957). As with all eukaryotes, yeast cells are compartmentalized into functionally distinct spaces by the creation of membranebo ...
... size before the process of cell division is initiated, and that the cells continue to grow as the cycle proceeds (Calvert and Dawes, 1984; Goranov et al., 2009; Mitchison, 1957). As with all eukaryotes, yeast cells are compartmentalized into functionally distinct spaces by the creation of membranebo ...
Carrier Proteins - HCC Learning Web
... • A plant cell in a solution hypotonic to the cell contents swells due to osmosis until the elastic cell wall exerts a back-pressure on the cell that opposes further uptake. – At this point the cell is turgid (very firm), a healthy state for most plant cells. Turgid cells contribute to the mechanica ...
... • A plant cell in a solution hypotonic to the cell contents swells due to osmosis until the elastic cell wall exerts a back-pressure on the cell that opposes further uptake. – At this point the cell is turgid (very firm), a healthy state for most plant cells. Turgid cells contribute to the mechanica ...
Microtubule cortical array organization and plant cell morphogenesis
... Although potentially important, the significance of treadmilling-mediated bundling in the creation and maintenance of cortical array organization remains to be determined. On their own, these activities cannot account for how the net orientation of the cortical microtubule array is selected. Other i ...
... Although potentially important, the significance of treadmilling-mediated bundling in the creation and maintenance of cortical array organization remains to be determined. On their own, these activities cannot account for how the net orientation of the cortical microtubule array is selected. Other i ...
No Slide Title
... Cell-free extracts of yeast rough ER plus cytosol and ATP vesicles form - COP II Formation - similar to COP I. Sec12 catalyzes exchange of GDP for GTP in th Sar I protein. Complex forms with Sec23 and Sec24 proteins, followed by binding of Sec13, Sec31, then Sec16. Contain a family of 24kDa proteins ...
... Cell-free extracts of yeast rough ER plus cytosol and ATP vesicles form - COP II Formation - similar to COP I. Sec12 catalyzes exchange of GDP for GTP in th Sar I protein. Complex forms with Sec23 and Sec24 proteins, followed by binding of Sec13, Sec31, then Sec16. Contain a family of 24kDa proteins ...
An Equatorial Contractile Mechanism Drives Cell Elongation but not
... drives cell shape changes. These fibers are organized in elaborate structures that form sarcomeres in the muscle and the contractile ring during cytokinesis. In cytokinesis, the establishment of an equatorial actomyosin ring is preceded and regulated by many cell cycle events, and the ring itself is ...
... drives cell shape changes. These fibers are organized in elaborate structures that form sarcomeres in the muscle and the contractile ring during cytokinesis. In cytokinesis, the establishment of an equatorial actomyosin ring is preceded and regulated by many cell cycle events, and the ring itself is ...
Ch 4_ Osmosis and Diffusion.pptx
... • Open in response to voltage differen?al across membrane – Nerve impulses ...
... • Open in response to voltage differen?al across membrane – Nerve impulses ...
Assembly - The Open Academy
... ear. However, as mitochondria n to move on microtubules, it kely that viral nucleocapsids o. Indeed, nucleocapsids were to be distributed throughout asm in close association with les (panel A below). Treatment d cells with drugs that disrupt les, such as nocodazole, dramatred this pattern: nucleocap ...
... ear. However, as mitochondria n to move on microtubules, it kely that viral nucleocapsids o. Indeed, nucleocapsids were to be distributed throughout asm in close association with les (panel A below). Treatment d cells with drugs that disrupt les, such as nocodazole, dramatred this pattern: nucleocap ...
The making of the Fittest: Natural Selection and Adaptation
... In an oxygen-rich environment, such as the lung, the HbA molecules are not attracted to one another and are freely distributed throughout the RBC. In an oxygen-poor environment, deoxygenated HbA molecules have the hydrophobic pocket, but they do not have the mutant valine to act as a donor. There is ...
... In an oxygen-rich environment, such as the lung, the HbA molecules are not attracted to one another and are freely distributed throughout the RBC. In an oxygen-poor environment, deoxygenated HbA molecules have the hydrophobic pocket, but they do not have the mutant valine to act as a donor. There is ...
Michael P. Kowalski1, Vipat Raksakulthai2
... the hanging drops for high content imaging. The transfer and dissociation of the spheroids into single cell suspensions was also automated to enable flow cytometry analysis. The Biomek FXP Workstation utilized Enhanced Multichannel Selective Tip Pipetting for rapid multichannel liquid transfer to pa ...
... the hanging drops for high content imaging. The transfer and dissociation of the spheroids into single cell suspensions was also automated to enable flow cytometry analysis. The Biomek FXP Workstation utilized Enhanced Multichannel Selective Tip Pipetting for rapid multichannel liquid transfer to pa ...
Autophagy and Immunity
... multiplication. Mutants localized to lysosomal-like vesicles, not autophagosomes. ‘Pregnant pause’ model says that autophagosome maturation is delayed to allow for pathogen ...
... multiplication. Mutants localized to lysosomal-like vesicles, not autophagosomes. ‘Pregnant pause’ model says that autophagosome maturation is delayed to allow for pathogen ...
7.2 powerpoint
... In many cells, the smooth ER contains collections of enzymes that perform specialized tasks, including the synthesis of membrane lipids and the detoxification of drugs. ...
... In many cells, the smooth ER contains collections of enzymes that perform specialized tasks, including the synthesis of membrane lipids and the detoxification of drugs. ...
Cytokinesis
Cytokinesis (cyto- + kinesis) is the process during cell division in which the cytoplasm of a single eukaryotic cell is divided to form two daughter cells. It usually initiates during the early stages of mitosis, and sometimes meiosis, splitting a mitotic cell in two, to ensure that chromosome number is maintained from one generation to the next. After cytokinesis two (daughter) cells will be formed that are exact copies of the (parent) original cell. After cytokinesis, each daughter cell is in the interphase portion of the cell cycle. In animal cells, one notable exception to the normal process of cytokinesis is oogenesis (the creation of an ovum in the ovarian follicle of the ovary), where the ovum takes almost all the cytoplasm and organelles, leaving very little for the resulting polar bodies, which then die. Another form of mitosis without cytokinesis occurs in the liver, yielding multinucleate cells. In plant cells, a dividing structure known as the cell plate forms within the centre of the cytoplasm and a new cell wall forms between the two daughter cells.Cytokinesis is distinguished from the prokaryotic process of binary fission.