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Diapositive 1 - Moodle Lille 2
Diapositive 1 - Moodle Lille 2

... Phase II* ...
Economic Consequences of Drug Abuse in Sri Lanka
Economic Consequences of Drug Abuse in Sri Lanka

... who were institutionalized. But there are many people who do not enter for treatments. These people are not considered in this study as they were not recorded in the relevant reports. These people do not consume government facilities or medical treatments for drug abuse. But they may create negative ...
product monograph
product monograph

... Patients with Parkinson’s Disease: Flupentixol should be used with caution in patients with Parkinsonism, as it is known that dopamine antagonists such as flupentixol, can cause a deterioration of the disease. Seizures: Flupentixol should be used with caution in patients with a history of convulsiv ...
Introduction to Genetics using Punnett Squares
Introduction to Genetics using Punnett Squares

... • Recessive describes a trait that is covered over (or dominated) by another form of that trait and seems to disappear. • Homozygous= two alleles that are the same for a trait (Pure) Ex. TT or tt • Heterozygous= two different alleles for a trait ...
GENETICS RESIDENT ELECTIVE Director
GENETICS RESIDENT ELECTIVE Director

... 5.40.12 : Develop strategies to learn about future advances in the understanding of genetic disorders, in order to incorporate into one's practice improved screening, identification, counseling and management of such disorders. 5.40.13 : Identify the indicators that would lead you to seek a genetics ...
Zurampic
Zurampic

... Indicated in combination with a xanthine oxidase inhibitor for the treatment of hyperuricemia associated with gout in patients who have not achieved target serum uric acid levels with a xanthine oxidase inhibitor alone.  Severe renal impairment, end stage renal disease and kidney transplant recipie ...
About the Naplex
About the Naplex

... Be sure to bring your ATT card and two forms of personal identification both with signature, at least one of which should also have your picture. They cannot be expired and must be the same name as your ATT. ...
Final Jeopardy - Lindbergh School District
Final Jeopardy - Lindbergh School District

... Although Janele’s blood is normal, her brother Randy has sickle-cell disease. Janele is worried about having a child with the disease. Janele just found out that her husband Terence has one allele for sickle-cell disease. This is the percent chance that Janele and Terence will have a child with sick ...
Geometric Statistics in PK analysis - Programmer`s
Geometric Statistics in PK analysis - Programmer`s

... Both drug concentration data and pharmacokinetic parameters usually follow a skewed distribution among patient population. Reaction rate or a transfer rate of drug in a patient’s body are proportional to the amount of substrate available on a given time point. In most cases, an enzyme inhibitor will ...
BREEDING BUNNIES State Standard 7.a. Students know why
BREEDING BUNNIES State Standard 7.a. Students know why

... Students know why natural selection acts on the phenotype rather than the genotype of an organism. State Standard 8.a. Student know how natural selection determine the differential survival of groups of organisms. Introduction In this activity, you will examine natural selection in a small populatio ...
Modern Genetics Jeopardy
Modern Genetics Jeopardy

... Although Janele’s blood is normal, her brother Randy has sickle-cell disease. Janele is worried about having a child with the disease. Janele just found out that her husband Terence has one allele for sickle-cell disease. This is the percent chance that Janele and Terence will have a child with sick ...
Key Initiatives in Medication Safety at LUHS
Key Initiatives in Medication Safety at LUHS

... • Errors and patient harm associated with medication treatment is a major issue for all healthcare organizations. • Medication safety is a major part of Loyola’s overall patient safety plan. • Key activities underway at LUHS are summarized here. ...
Psychosis
Psychosis

... Efficacy: good for both +ve and –ve. : good for tx of acute : last line  mostly in resistant cases ...
outline25282 - American Academy of Optometry
outline25282 - American Academy of Optometry

... Inheritance patterns A. Introduction. 1. Because the role that genetic factors play in pathologic processes is now better understood, the importance of genetics in optometry and medicine has increased. Scientific advances have made it possible to identify genetic diseases more precisely, to provide ...
Different noses for different mice and men - Leslie Vosshall
Different noses for different mice and men - Leslie Vosshall

... perceived and it has already been shown that, in some cases, genetic variability in ORs influences how strong and pleasant the ligands of the ORs are perceived to be [6]. Similar to the findings in human ORs, Wynn et al. [1] found that, for a large percentage of mouse VR genes, both an intact versio ...
BASICS OF CONGENITAL ANOMALIES
BASICS OF CONGENITAL ANOMALIES

Document
Document

... a head-to-head comparison with ACEIs.  Losartan was not superior to captopril in patients with heart failure( ELITE II) , captopril reduced CV-death in post-MI patients more than losartan( OPTIMAAL) However, both of these studies found that less patients discontinued losartan due to adverse effects ...
Towards new treatment for breast cancer
Towards new treatment for breast cancer

... underlying it can be very helpful for determining the proper treatment. If an oncologist knows that a breast tumour has a mutation in one of the Breast Cancer (BRCA) genes, he knows that the tumour cells lacks an important DNA repair mechanism. Therefore, he knows that treatment through the inhibiti ...
Chapter 5 Power Point
Chapter 5 Power Point

... – Nursing staff generally administer medications to patients. – Patient charts are referred to prior to administration because they provide the most up-to-date physician instructions. ...
Real Cats Wear Pink
Real Cats Wear Pink

... To show that the gene went where it was supposed to go, the researchers settled on one that would glow. The gene “is just a marker,” said Leslie Lyons, an assistant professor of population health and reproduction at the School of Veterinary Medicine at the University of California, Davis, who is fam ...
chapteroutline_ch07
chapteroutline_ch07

... sperm or eggs produced by an individual are different from one another, and any one of those gametes may be the gamete involved in fertilization. 7.7 A test-cross enables us to figure out which alleles an individual carries. TAKE-HOME MESSAGE 7.7: In a test-cross, an individual that exhibits a domin ...
PDF, 288KB - Queensland Courts
PDF, 288KB - Queensland Courts

... Paracetamol approximately 15 milligrams per kilogram ...


... today as alleles of a gene • Diploid organisms have two alleles for every gene • Alleles are passed sexually & asexually • Variation arises during sexual reproduction where offspring receives different alleles than either of the parents ...
Laminil Investigational Drug
Laminil Investigational Drug

... using retrograde venous therapy. We tested other routes such as systemic intravenous injection, oral, and topically with a patch, but at this date, retrograde venous therapy shows superior efficacy. Protein binding: The drug is approximately 89 percent protein bound in human plasma. No data is avail ...
Uptravi
Uptravi

... • No difference in mortality between groups • Addition of selexipag to baseline regimen of two meds gave benefits consistent with overall treatment effect • Similar efficacy regardless of dose range Sitbon O, et al. N Engl J Med. 2015;373(26):2522-33. ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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