• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Document
Document

... and exercise history, history of present illness, and economic situation (financial and insured status). Sources of information may include, but are not limited to, the patient, medical charts and reports, pharmacist-conducted health/physical assessment, the patient's family or caregiver, insurer, a ...
Name: : ______ Notes 11.3 – Other Patterns of Inheritance THINK
Name: : ______ Notes 11.3 – Other Patterns of Inheritance THINK

... MULTIPLE ALLELES 11. A gene with more than _______ alleles is said to have _____________ ___________. 12. Fill in the blanks….. ...
Carbamazepine VS Oxcarbazepine
Carbamazepine VS Oxcarbazepine

... • Mechanism  Ion channel blockers Enhances GABA • It is well absorbed and peak levels are reached within 2 hours. • It is rapidly broken down to its pharmacologically active form which is then excreted through the kidneys. ...
INCOMPATIBILITIES IN PRESCRIPTION Definition of Incompatibility
INCOMPATIBILITIES IN PRESCRIPTION Definition of Incompatibility

... covers & handed over to the right person. ...
Pam Lyons - Pitt Pharmacy Portfolio
Pam Lyons - Pitt Pharmacy Portfolio

... Step 3: Identification of Drug Therapy Problems: 2 ...
Drugs → brain structures AP MST Bipolar disorder NICE Diagnosis
Drugs → brain structures AP MST Bipolar disorder NICE Diagnosis

... striatum by antipsychotics with high dopamine receptor affinity and in the cortex by antipsychotics with mixed serotonergic/dopaminergic profile ...
Cross Addictions and Safe Medications
Cross Addictions and Safe Medications

... see your doctor for insomnia, pain, anxiety, etc., he may give you perfectly good medications, and be a wellmeaning doctor, but some of those medicines will lead you right back to alcohol. In an effort to try and help you when you leave here, we have compiled a list of acceptable safe medications an ...
Concerns regarding the safety and toxicity of medicinal plants
Concerns regarding the safety and toxicity of medicinal plants

... common man. Synthetic drugs usually consist of a single chemical, while medicinal plants can contain complex mixture of 400 or more chemicals. It’s comparatively easy to figure out the activity and side effects of a single chemical, but there is just no way scientists can map all the complex interac ...
IS IT GENETIC? How do genes, environment and chance interact to
IS IT GENETIC? How do genes, environment and chance interact to

... tested why stressful experiences lead to depression in some people but not in others. A functional polymorphism in the promoter region of the serotonin transporter (5-HT T) gene was found to moderate the influence of stressful life events on depression. Individuals with one or two copies of the shor ...
Kinetics and dynamics HW exercise
Kinetics and dynamics HW exercise

... tissue. Only unbound drug is available to have its effects on the body. The amount of albumin in the blood can modify the availability of a drug in the body. Metabolism: Is the body’s way to get rid of lipid soluble compounds, so they can be eliminated through the kidneys in urine. Enzymes in the li ...
`It`s alive!` How tiny `organs` on microchips could replace mice and
`It`s alive!` How tiny `organs` on microchips could replace mice and

... you drug efficacy, toxicity,” said Prof. Ingber. “So that’s what we’re doing. We’re building an automated instrument that would literally have 10 DVD-like cassettes and each one holds a chip, a different organ. “ His and other groups are also working on linking organs via fluid channels into a singl ...
Pharmacogenetics in the Brazilian population
Pharmacogenetics in the Brazilian population

... recently reported to be substrates of the SLCO1B1/OATP1 drug transporter, and a SNP (521T > C) in the SLCO1B1 gene was associated with plasma levels of lopinavir in HIV-infected individuals ...
SSRI`s and the Black Box Warning: Patient Advocacy or Alarmist
SSRI`s and the Black Box Warning: Patient Advocacy or Alarmist

... youth including arguments by physicians who support the continued use of these medications in the treatment of depression, however, the damage has been done. Most people reading this article are not going to come away with the message that many practitioners still believe that SSRI’s are an importan ...
Drug Induced Liver Disease
Drug Induced Liver Disease

... databases for known interactions • Screen for initial mild liver damage before it becomes severe - AST/ALT most used • Holy Grail: tailor drugs to patient’s genetic/environmental/drug profile ...
MS Word worksheet
MS Word worksheet

... dominant allele vs. recessive allele ...
SOUTH PLAINS COLLEGE – PLAINVIEW
SOUTH PLAINS COLLEGE – PLAINVIEW

... administration, and documentation of multiple forms of drugs will be covered. Instruction includes various systems of measurement. COURSE LEARNING OBJECTIVES: The student will demonstrate accurate dosage calculation; discuss the principles of medication administration safety; and identify the elemen ...
Reinforcement & Drug Effects
Reinforcement & Drug Effects

... Operant Conditioning Acquisition & Maintenance of behavior ...
REAL-WORLD DATA STRATEGIES
REAL-WORLD DATA STRATEGIES

... level. These are large, historical, longitudinal data sets that can provide insight into the patient journey. But they provide very limited information on patient vitals and clinical results, such as blood pressure, weight, or blood tests.  OSPITAL EVENT DATA. RWD from hospitalizations is H also av ...
Antifungal drugs
Antifungal drugs

... -F(oral): < 1% (too irritant to be given IM) -Distribution in all body tissues, except CNS and eye (concentrations in CSF are <10% than in plasma; however therapeutic concentrations in CNS can usually be achieved with parenteral administration) -Biotransformation: > 95% -Renal excretion: < 5% -Half ...
Neurology Firm NuPathe Gets $15M For Lead Migraine Patch
Neurology Firm NuPathe Gets $15M For Lead Migraine Patch

... While its lead migraine product prepares for Phase III trials next year, NuPathe Inc. raised $15 million in a Series A round enough to take the young firm to a regulatory filing within two years. “It’s our first big venture round. We’ve only had seed financing before, so this is a critical raise for ...
HOW TO USE THIS BOOK
HOW TO USE THIS BOOK

... • A retrospective study of 286 cases of isolated aripiprazole exposures found 55% of patients reported symptoms – somnolence (56%), sinus tachycardia (20%), nausea/vomiting (18%), dystonia (13%), tremor (6%), agitation, dizziness (2%), paresthesias, headache (1%). There were no reports of death, res ...
Drug Therapy in Pediatric Patients
Drug Therapy in Pediatric Patients

... The nurse provides teaching for the caregiver of a 2-monthold infant and a 3-year-old child. Both children will be taking oral ampicillin (an acid-labile drug) to treat a bacterial infection. The nurse determines that teaching is successful if the caregiver makes which of the following statements? A ...
MONTRÉAL (Québec), Canada – August 5, 2013 – gIcare Pharma
MONTRÉAL (Québec), Canada – August 5, 2013 – gIcare Pharma

... The double-blind, randomized, placebo-controlled, dose-ranging trial will enroll 240 patients in the US and Canada, to assess the efficacy and safety of GIC-1001 for sedation-less colorectal cancer (CRC) screening using video-colonoscopy. “GIC-1001 was shown to be safe during Phase I trials and we a ...
Chapter 14 Drugs - Ozark R
Chapter 14 Drugs - Ozark R

... Psychologically they crave the feeling the drug brings and painful physical withdrawal symptoms make it very difficult for the user to quit the drug. ...
Oncurious NV Announces FDA Acceptance of Investigational New
Oncurious NV Announces FDA Acceptance of Investigational New

... of Relapsed or Refractory Medulloblastoma. This is a rare, life-threatening brain tumor that mainly affect children. The study, which is planned to commence in Q1 2016, will be conducted at a number of specialist centers in the United States. Initial results from the study are expected by early 2017 ...
< 1 ... 1059 1060 1061 1062 1063 1064 1065 1066 1067 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report