Structure, Expression and Duplication of Genes Which Encode
... isolated. All contained anidentically sized insert of 1 kb. The clones were sequenced and found to contain a PGLYM encoding open reading frame by comparison to the human PGLYM amino acid sequence. ADrosophila cDNA clone was used to probe a Southernblot of Drosophila genomic DNA. This analysis (Figur ...
... isolated. All contained anidentically sized insert of 1 kb. The clones were sequenced and found to contain a PGLYM encoding open reading frame by comparison to the human PGLYM amino acid sequence. ADrosophila cDNA clone was used to probe a Southernblot of Drosophila genomic DNA. This analysis (Figur ...
The nucleotide sequence of Saccharomyces cerevisiae
... chromosome X a large, nearly identical block of sequence similarity more than 19 kilobases long. This duplication includes five ORFs, which code for almost identical products. Indeed the sequences are so similar that we needed to exclude the possibility of contamination of the cosmid contig of chrom ...
... chromosome X a large, nearly identical block of sequence similarity more than 19 kilobases long. This duplication includes five ORFs, which code for almost identical products. Indeed the sequences are so similar that we needed to exclude the possibility of contamination of the cosmid contig of chrom ...
... However, it is not realistic to expect, for example, that the thousands of N. crassa genes that have NCU numbers and orthologs in other species be referred to only by their NCU numbers until such time as N. crassa experimental data provide the basis for a name. Therefore, we consider how to provide ...
Information Encoding in Biological Molecules: DNA and
... sequence data and examine the expression of the human orthologs. • Enter any gene to start. • In configure menu: (a) Expand tissue selection of GNF Atlas 2 to “median of replicas”, (b) click on human homologs • In filter menu: (a) set adrenal gland minimum box to 2.5, (b) look at results and set max ...
... sequence data and examine the expression of the human orthologs. • Enter any gene to start. • In configure menu: (a) Expand tissue selection of GNF Atlas 2 to “median of replicas”, (b) click on human homologs • In filter menu: (a) set adrenal gland minimum box to 2.5, (b) look at results and set max ...
Identification of large-scale human-specific copy number
... Number of changes detected by aCGH in primate genomes For each of the primate species investigated (PTR, PPA, GGO, PPY and MFA), DNA from ten unrelated females was pooled, labeled and hybridized together with the differently labeled human reference DNA pool, also consisting of ten unrelated (female) ...
... Number of changes detected by aCGH in primate genomes For each of the primate species investigated (PTR, PPA, GGO, PPY and MFA), DNA from ten unrelated females was pooled, labeled and hybridized together with the differently labeled human reference DNA pool, also consisting of ten unrelated (female) ...
Applied and Environmental Microbiology
... No significant differences in enzyme expression could be found among the celB10-marked derivatives in liquid culture, indicating that expression is largely independent of insertion position in the genome. In the presence of IPTG, which alleviated lacIq-mediated repression, a 10-fold-higher level of ...
... No significant differences in enzyme expression could be found among the celB10-marked derivatives in liquid culture, indicating that expression is largely independent of insertion position in the genome. In the presence of IPTG, which alleviated lacIq-mediated repression, a 10-fold-higher level of ...
Document
... Genome rearrangement is a crucial event for reorganizing the new MAC for efficient replication and transcription. Common programmed genome rearrangements include chromosome fragmentation, elimination of centromeres and repetitive DNA, ribosomal gene amplification, and the excision of “internal elimi ...
... Genome rearrangement is a crucial event for reorganizing the new MAC for efficient replication and transcription. Common programmed genome rearrangements include chromosome fragmentation, elimination of centromeres and repetitive DNA, ribosomal gene amplification, and the excision of “internal elimi ...
Ecophysiology of Thioploca ingrica as revealed by the
... Large sulfur-oxidizing bacteria, which accumulate a high concentration of nitrate, are important constituents of aquatic sediment ecosystems. No representative of this group has been isolated in pure culture, and only fragmented draft genome sequences are available for these microorganisms. In this ...
... Large sulfur-oxidizing bacteria, which accumulate a high concentration of nitrate, are important constituents of aquatic sediment ecosystems. No representative of this group has been isolated in pure culture, and only fragmented draft genome sequences are available for these microorganisms. In this ...
a database designed for the polymorphisms of the human ccr2 gene
... We have developed a specialized database that contains information about polymorphic markers (predominantly SNPs) in the CCR2 gene and its neighboring DNA regions, their population frequencies and also about the trait and diseases associated with these polymorphisms. The database consists of 4 inter ...
... We have developed a specialized database that contains information about polymorphic markers (predominantly SNPs) in the CCR2 gene and its neighboring DNA regions, their population frequencies and also about the trait and diseases associated with these polymorphisms. The database consists of 4 inter ...
Gibson Second Edition
... 1. Generation of high-resolution genetic and physical maps that will help in the localization of disease-associated genes. 2. The attainment of sequence benchmarks, leading to generation of a complete genome sequence by the year 2005. (A draft version was achieved in May 2000, but finished sequence ...
... 1. Generation of high-resolution genetic and physical maps that will help in the localization of disease-associated genes. 2. The attainment of sequence benchmarks, leading to generation of a complete genome sequence by the year 2005. (A draft version was achieved in May 2000, but finished sequence ...
Journal of Molecular Evolution
... lation geneticists and empirical evidence has been provided for it by molecular biologists working with hybrid phages (Furth and Yates 1978; Susskind and Botstein 1978), from reversion studies of bacterial mutants (Ebright et al. 1985), and from interspecific hybrids of the mammalian cytochrome chai ...
... lation geneticists and empirical evidence has been provided for it by molecular biologists working with hybrid phages (Furth and Yates 1978; Susskind and Botstein 1978), from reversion studies of bacterial mutants (Ebright et al. 1985), and from interspecific hybrids of the mammalian cytochrome chai ...
Complex History of a Chromosomal Paralogy Region: Insights from
... two or more linked gene families within a paralogy group. Amphioxus may be the ideal outgroup for such analyses since it is the sister group of the vertebrates (defined here as synonymous with craniates) and is thought to have branched from the chordate lineage just before the putative tetraploidy e ...
... two or more linked gene families within a paralogy group. Amphioxus may be the ideal outgroup for such analyses since it is the sister group of the vertebrates (defined here as synonymous with craniates) and is thought to have branched from the chordate lineage just before the putative tetraploidy e ...
Gene Access Brochure - Australian Clinical Labs
... having children with the condition. Approximately 1 in 250 females in the general population carry a genetic change that puts them at risk of having a child affected with FXS. The disease is seen across all ethnic groups and ...
... having children with the condition. Approximately 1 in 250 females in the general population carry a genetic change that puts them at risk of having a child affected with FXS. The disease is seen across all ethnic groups and ...
Independent specialization of the human and mouse X
... tral X-linked gene, we also analyzed orthologous genes in dog, horse and chicken for comparison. Only a small fraction of the 11.5 Mb of sequence generated, 3.15 Mb comprised X-chromosomal genes (13/144 in humans and 29/197 in mice) that violated Ohno’s amplicons. We estimated the total size of the ...
... tral X-linked gene, we also analyzed orthologous genes in dog, horse and chicken for comparison. Only a small fraction of the 11.5 Mb of sequence generated, 3.15 Mb comprised X-chromosomal genes (13/144 in humans and 29/197 in mice) that violated Ohno’s amplicons. We estimated the total size of the ...
Meiosis and Mendel`s Law of Segregation
... Recombination is the exchange of DNA sequences between two chromatids at a given loci, which may result in single chromatids that contain both maternal and paternal DNA sequences. Recombination occurs in Prophase of Meiosis I (when the homologous chromosomes pair up), which takes place after DNA rep ...
... Recombination is the exchange of DNA sequences between two chromatids at a given loci, which may result in single chromatids that contain both maternal and paternal DNA sequences. Recombination occurs in Prophase of Meiosis I (when the homologous chromosomes pair up), which takes place after DNA rep ...
Genome-wide scan with SNPs
... microsatellite markers spaced at intervals of approximately 10 cM across the genome. However, there is a growing realization that a map of closely spaced single-nucleotide polymorphisms (SNPs) may offer equal or superior power to detect linkage, compared with low-density microsatellite maps. Genome- ...
... microsatellite markers spaced at intervals of approximately 10 cM across the genome. However, there is a growing realization that a map of closely spaced single-nucleotide polymorphisms (SNPs) may offer equal or superior power to detect linkage, compared with low-density microsatellite maps. Genome- ...
Immunome database for marsupials and monotremes Open Access
... identified sequences and 3,197 sequences which had been described previously. This comprehensive dataset was built from a variety of sources, including EST projects and expert-curated gene predictions generated through a variety of methods including chained-BLAST and sensitive HMMER searches. To fac ...
... identified sequences and 3,197 sequences which had been described previously. This comprehensive dataset was built from a variety of sources, including EST projects and expert-curated gene predictions generated through a variety of methods including chained-BLAST and sensitive HMMER searches. To fac ...
El Proyecto Genoma Humano
... • BioProject is an administrative object (defined by goal, target, funding, collaboration) • Genome is a biological object defining an organism at molecular level • Genome assembly is a complex data structure that defines the structure, relative position (scaffold) and chromosome placement of DNA se ...
... • BioProject is an administrative object (defined by goal, target, funding, collaboration) • Genome is a biological object defining an organism at molecular level • Genome assembly is a complex data structure that defines the structure, relative position (scaffold) and chromosome placement of DNA se ...
Rate Asymmetry After Genome Duplication Causes Substantial
... However, a previous study of gene pairs formed by WGD in the yeast Saccharomyces cerevisiae found conflicting topologies among neighbor-joining (NJ) trees drawn from different loci and suggested that this conflict was the result of ‘‘asynchronous functional divergence’’ of duplicated genes (Langkjae ...
... However, a previous study of gene pairs formed by WGD in the yeast Saccharomyces cerevisiae found conflicting topologies among neighbor-joining (NJ) trees drawn from different loci and suggested that this conflict was the result of ‘‘asynchronous functional divergence’’ of duplicated genes (Langkjae ...
Session-3.-Molecular..
... mechanisms has remained a bottleneck. Recent systems biology tools have significantly shortened the time required to proceed from a mapped locus to testing of candidate genes. These tools enable research on natural variation to move from simple reductionistic studies focused on individual genes to i ...
... mechanisms has remained a bottleneck. Recent systems biology tools have significantly shortened the time required to proceed from a mapped locus to testing of candidate genes. These tools enable research on natural variation to move from simple reductionistic studies focused on individual genes to i ...
Varicella-Zoster Virus Specifies a Thymidylate Synthetase
... only in the strain containing pGL271, which expresses the VZV TS gene, and not in the host strain alone or in the host strain containing the vector plasmid without the TS gene. A similar result was obtained using an independent clone containing the VZV TS gene on a smaller N c o I XbaI fragment (dat ...
... only in the strain containing pGL271, which expresses the VZV TS gene, and not in the host strain alone or in the host strain containing the vector plasmid without the TS gene. A similar result was obtained using an independent clone containing the VZV TS gene on a smaller N c o I XbaI fragment (dat ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.