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manual of aliquotG
manual of aliquotG

... vertices, add an edge connecting them into a graph PG(H) (i.e. the partial graph of genome H. H is empty initially, and is the result Gdup at last), and assign a weight r to the edge (where r is the duplicated size, or number of genes of each gene family). And we label and contract all matched pair ...
TOC  - G3: Genes | Genomes | Genetics
TOC - G3: Genes | Genomes | Genetics

problem set5
problem set5

... are more closely related to each other than either are to Tongan fruit bats (P. tonganus), the protein sequence of the Pap2L gene in P. anetianus is more similar to P. tonganus than it is to P. samoensis. Mutants for the Pap2L gene in P. samoensis are unable to detect papaya groves when foraging at ...
Biology First Six Weeks Vocabulary
Biology First Six Weeks Vocabulary

... An Austrian monk and botanist who established key principles for the study of genetics; the father of genetics ...
A Genetic Approach to Ordered Sequencing of Arabidopsis
A Genetic Approach to Ordered Sequencing of Arabidopsis

... What can we learn from comparative analysis • Evolutionary relationships • Better annotation of genes, particularly of beginning and ends of genes • Detection of conserved regulatory regions • Functional evidence ...
Citrus Breeding - Aggie Horticulture
Citrus Breeding - Aggie Horticulture

... • Natural mechanism for species to maintain genetic uniformity- pummelo, mandarins • Serious inbreeding depression in citrus overcome by apomixis- nucellar embryony • Important for gene inheritance and function studies ...
mapping
mapping

... 2. Analyze recombination frequency a) Recombinational frequency is proportional to distance between gene B. Linkage and multifactor crosses 1. Definitions a) Linkage (1) Two genes very close to each other so recombination between them would be very rare b) Multifactor (1) Looking at three or more ge ...
Proposed technology: Multi-chambered microfluidic
Proposed technology: Multi-chambered microfluidic

... – $0.65 – $1.10 per bp for custom gene synthesis services – Example: synthesis of bacterial genomes 106bp in size become prohibitively costly, requiring on the order of $100, 000 in oligos alone ...
Methods Used in Medical and Population Genetics
Methods Used in Medical and Population Genetics

... the population, taking note of single nucleotide ...
Chp. 2, Section A: Introduction to Inheritance
Chp. 2, Section A: Introduction to Inheritance

... The dogs in the diagram on the opposite page can be used to illustrate this sort of dominant-recessive relationship between two versions of a single gene. The top part of the diagram indicates that when a particular black and white dog mated, all of their offspring were black. However, the middle pa ...
C15_Chan
C15_Chan

... Case-Control Association Studies ...
No Slide Title
No Slide Title

... Molecular Basis for Relationship between Genotype and Phenotype ...
Praktikum Information Integration - HU
Praktikum Information Integration - HU

... annotations, have a connected protein (with a protein_id and a protein_version_id), have a status, are on a chromosome, have a start and end position, and a chromosomal location – Gene function: Are described by a taxonomy of terms which forms a DAG; each term has an ID, a name, a description, and c ...
seminar
seminar

... A large gap in the top level of the net is filled by an inversion containing two genes. Numerous smaller gaps are filled in by local duplications and processed pseudo-genes. ...
Notes on Haldane`s mapping function and physical and recomb maps
Notes on Haldane`s mapping function and physical and recomb maps

... physical map. Physical maps involve measuring the distances between genes in terms of the numbers of basepairs of DNA. These can be obtained through sequencing of the entire genome, as for many model organisms (or sequencing a portion of the genome of interest). The gene order of both maps should be ...
Hemochromatosis gene nomenclature
Hemochromatosis gene nomenclature

... maybe there was some clash with a more obvious symbol, or maybe FE was thought to be memorable because of the iron. However, the main purpose of assigning a symbol at that stage was to indicate its position easily on a genetic map. The designation of the cloned gene (Genbank ID: U60319) as HLA-H, wh ...
Fact Sheet 55|HUNTINGTON DISEASE In summary Huntington
Fact Sheet 55|HUNTINGTON DISEASE In summary Huntington

... the huntingtin protein also becomes longer and this appears to interfere with its function, therefore a copy of the HTT gene with an expanded CAG repeat length can be considered faulty. The number of CAG repeats can increase when the HTT gene is passed from a parent to a child, this is known as anti ...
Power Point 3 - G. Holmes Braddock
Power Point 3 - G. Holmes Braddock

... Mendel's Law of Segregation states that allele pairs separate or segregate during gamete formation, and randomly unite at fertilization. ...
Gene regulation
Gene regulation

... • It is thought to bind more than 20 different proteins • It is very sensitive to the position of the gene (nucleus) within the developing giant cell • The different concentrations of the different proteins impact on the expression of ‘Eve’ ...
Personal genomics as a major focus of CSAIL research
Personal genomics as a major focus of CSAIL research

... Rank all probes by Alzheimer’s association 7000 probes increase methylation (repressed) Enriched in brain-specific enhancers Near motifs of brain-specific regulators ...
Comparing Different Linear Expression Systems
Comparing Different Linear Expression Systems

... A promoter for any of these genes is put next to the gene for rtTA; transcription of the gene rtTA is activated. rtTA makes a tetracycline activator, but with a twist: it only works when doxycycline is present. Then, dox and the tet activator form a complex, and they bind to a special promoter, cons ...
Worksheet - Verona Agriculture
Worksheet - Verona Agriculture

... A. Click on "Gene Control," read the page and answer the following questions: 1. Describe the following characteristics when a gene is active: a. Is the gene tightly or loosely wound around histones? b. Are there many or few methyl molecules attached to the gene? c. Are there many or few acetyl mole ...
Inheritance Patterns - Osteogenesis Imperfecta Foundation
Inheritance Patterns - Osteogenesis Imperfecta Foundation

... one child with OI. In recessive OI, both copies of a particular gene received by the child are altered (have a mutation). Each parent of the affected child is a carrier of one copy of the altered gene, but neither parent is affected. When both parents are each carriers for recessive OI, there is a 2 ...
Personal genomics as a major focus of CSAIL research
Personal genomics as a major focus of CSAIL research

... Enriched in brain-specific enhancers Near motifs of brain-specific regulators ...
epigenetic webquest 2014
epigenetic webquest 2014

... The Epigenome Learns from its Experiences 6. True or False – Cell signals play a role in shaping gene expression only during development. ...
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Copy-number variation



Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.
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