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1. True or False? A typical chromosome can contain

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DNA Structure, Function and Replication 1

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DNA extraction from cheek cells protocol I mailed to you
DNA extraction from cheek cells protocol I mailed to you

... DNA carries the genetic information in all living organisms, including humans, other animals, plants, and bacteria. Each cell in your body has a nucleus with multiple chromosomes. Each chromosome contains a DNA molecule with multiple genes. Each gene is a segment of DNA that provides the instruction ...
03 Nucleic Acids
03 Nucleic Acids

... Each nucleotide consists of three smaller molecules: 1. sugar 2. phosphate group 3. nitrogen base If you look at Figure 1.1, you will see that the sugar of one nucleotide binds to the phosphate group of the next nucleotide. These two molecules alternate to form the backbone of the nucleotide chain. ...
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Holliday junction



A Holliday junction is a branched nucleic acid structure that contains four double-stranded arms joined together. These arms may adopt one of several conformations depending on buffer salt concentrations and the sequence of nucleobases closest to the junction. The structure is named after the molecular biologist Robin Holliday, who proposed its existence in 1964.In biology, Holliday junctions are a key intermediate in many types of genetic recombination, as well as in double-strand break repair. These junctions usually have a symmetrical sequence and are thus mobile, meaning that the four individual arms may slide though the junction in a specific pattern that largely preserves base pairing. Additionally, four-arm junctions similar to Holliday junctions appear in some functional RNA molecules.Immobile Holliday junctions, with asymmetrical sequences that lock the strands in a specific position, were artificially created by scientists to study their structure as a model for natural Holliday junctions. These junctions also later found use as basic structural building blocks in DNA nanotechnology, where multiple Holliday junctions can be combined into specific designed geometries that provide molecules with a high degree of structural rigidity.
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