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Chemical, pharmacokinetic and pharmacodynamic properties of
Chemical, pharmacokinetic and pharmacodynamic properties of

... triglyceride-rich lipoproteins [5,6]. In addition, statins may exert beneficial cardiovascular effects independent of their lipid-modifying properties [7]. These pleiotropic properties may be explained by inhibition of synthesis of nonsteroidal isoprenoid compounds, which are also produced from meva ...
Multiple-Drug Toxicity Caused by the Coadministration of 4
Multiple-Drug Toxicity Caused by the Coadministration of 4

... order to maintain the initial effects of the drug (5). Side effects of mephedrone reported by users include skin rashes, numbness, headache, and minor amnesia (5). More serious side effects noted after large doses of mephedrone were skin discoloration, light-headedness, cramping, and aches (5). Beca ...
Methamphetamine Action Plan
Methamphetamine Action Plan

... and enhanced mood. The effects of methamphetamine are dose dependent, however, the following effects will occur at greater or lesser levels; euphoria, increased activity and energy levels, dis-inhibition, sense of well-being, increased confidence (often termed ‘bullet-proof’), decreased appetite and ...
Omeprazole - School Nurse
Omeprazole - School Nurse

... Some conditions are treated with a combination of omeprazole and antibiotics. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Taking a proton ...
Rapid and Sensitive HPLC Method for the Determination of
Rapid and Sensitive HPLC Method for the Determination of

... rejection in organ transplantation especially useful in kidney transplants approved by the Food and Drug Administration. ...
UAB Comprehensive Cancer Center Clinical Trials Audit Manual
UAB Comprehensive Cancer Center Clinical Trials Audit Manual

... Several resources are available to provide an overall assessment of active investigator-initiated protocols. A list of these resources is as follows but is not limited to:  A UAB Cancer Center Clinical Trials database of protocols is used to provide pertinent information for registered and newly re ...
Didanosine - WHO archives - World Health Organization
Didanosine - WHO archives - World Health Organization

... treatment. A prospective observational cohort study was undertaken to assess the feasibility, effectiveness, adherence, toxicity and viral resistance of antiretroviral therapy. The clinical and biological results of the study were comparable to those seen in western cohorts, despite differences in H ...
Imovane (zopiclone)
Imovane (zopiclone)

... depression that could be intensified by hypnotic drugs. The potential for self-harm (e.g., intentional overdose) is high in patients with depression and thus, the least amount of drug that is feasible should be available to them at any one time. As with other hypnotics, IMOVANE does not constitute a ...
MDMA (Ecstasy) - cloudfront.net
MDMA (Ecstasy) - cloudfront.net

... It is also important to keep in mind that many users of ecstasy may unknowingly be taking other drugs that are sold as ecstasy, and/or they may intentionally use other drugs, such as marijuana, which could contribute to these behavioral effects. Additionally, most studies in people do not have behav ...
Vol.32, No.5 & 6 May-June 2002 ISSN 0377-4910
Vol.32, No.5 & 6 May-June 2002 ISSN 0377-4910

... adenolymphangitis result in progression of chronic lymphoedema from early reversible to late elephantiasis1,23,25. Thus prevention of acute disease will not only bring down the suffering of patients, but also check progression of lymphoedema to disfiguring stages. Bacterial infections, particularly ...


... that deals with this is pharmacokinetics, abbreviated PK. It involves a modelling part in which data obtained from clinical studies are used to describe how the drug is handled by and distributed in the body. Clinical pharmacokinetics is the bedside application of this information, assuring that the ...
The diagnosis and management of benzodiazepine dependence Heather Ashton
The diagnosis and management of benzodiazepine dependence Heather Ashton

... to make them ideal medications for many common conditions (Table 1). The drugs were prescribed long term, often for many years, for complaints such as anxiety, depression, insomnia and ordinary life stresses. Benzodiazepines were undoubtedly efficacious at first for these conditions, and apparently ...
The diagnosis and management of benzodiazepine dependence
The diagnosis and management of benzodiazepine dependence

... to make them ideal medications for many common conditions (Table 1). The drugs were prescribed long term, often for many years, for complaints such as anxiety, depression, insomnia and ordinary life stresses. Benzodiazepines were undoubtedly efficacious at first for these conditions, and apparently ...
API Particle Engineering Innovations
API Particle Engineering Innovations

... • Key Considerations: Must meet cost, scale-up, and development time requirements ...
Prescribing Information - Auvi-Q
Prescribing Information - Auvi-Q

... Auvi-Q® is indicated in the emergency treatment of allergic reactions (Type I) including anaphylaxis to stinging insects (e.g., order Hymenoptera, which include bees, wasps, hornets, yellow jackets and fire ants) and biting insects (e.g., triatoma, mosquitoes), allergen immunotherapy, foods, drugs, ...
The substituted amphetamines 3,4
The substituted amphetamines 3,4

... nM).Non-specific uptake, which accounted for 10% of total uptake, was determined in presence of 10 -4 M fluoxetine. To terminate the uptake, synaptosomes were spun down for 5 min at 2400 ×g, resuspended in buffer and spun again for 5 min at 2400 × g. The final pelletwas resuspended in 12.5 volumes/g ...
Anabolic Steroids
Anabolic Steroids

... The history of anabolic steroids can be traced back to as early as the 1930’s, before the term steroid was even used. In the 1930’s, a team of scientists was able to create a synthetic form of testosterone to help treat men who were unable to produce enough of the hormone for normal growth, developm ...
Clinical Medicine: Therapeutics pharmacotherapy of Fibromyalgia
Clinical Medicine: Therapeutics pharmacotherapy of Fibromyalgia

... Objectives: Tricyclic antidepressants were the first drugs used to treat FMS. More recently, among serotonin-norepinephrine reuptake inhibitors, duloxetine was approved by US Food and Drug Administration to treat FMS. Duloxetine is used for the management of major depressive disorder, neuropathic pa ...
Evaluating Inhaled Steroids Used to Treat
Evaluating Inhaled Steroids Used to Treat

... Without that competition, the manufacturers have been able to increase the price—an average of 50 percent since 2009, with some medications jumping 80 percent or more in price. For example, QVAR 80 mcg, at $177 for a month’s supply, is 92 percent more expensive than it was in 2009, according to pric ...
CURRICULUM VITAE Stacey C. Sigmon, Ph.D. February 2014
CURRICULUM VITAE Stacey C. Sigmon, Ph.D. February 2014

... Higgins, S.T., Sigmon, S.C., & Heil, S.H. (2011). Contingency management in the treatment of substance use disorders: Trends in the literature. In P. Ruiz & E. Strain (Eds.), Lowinson & Ruiz’s Substance Abuse: A Comprehensive Textbook, Fifth Edition. Maryland: Lippincott Williams & Wilkins, pp. 603- ...
) PCH
) PCH

... psoriasis, and adult rheumatoid arthritis, Methotrexate inhibits dihydrofolic acid reductase. Dihydrofolates must be reduced to tetrahydrofolates by this enzyme before they can be utilized as carriers of one-carbon groups in the synthesis of purine nucleotides and thymidylate. Therefore, methotrexat ...
Controlled Substance Management
Controlled Substance Management

... B. 3% B. Antagonism of sedative or hypnotic actions C. 7% C. Competition for plasma protein binding D. 17% D. Induction of liver drug-metabolizing enzymes E. 33% E. Inhibition of liver drug-metabolizing enzymes 2354. According to the DSM-IV, which of the following is NOT 2350. A patient presents for ...
Full Prescribing Information
Full Prescribing Information

... Clostridium difficile Associated Diarrhea Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including Doryx MPC Tablets, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal ...
Addiction neurobiology: Ethical and social implications
Addiction neurobiology: Ethical and social implications

... ethical issues that they raise for drug policy in Europe. The reader will find that it is difficult not to be both excited and apprehensive when considering the implications of the developments occurring in this field. Neuroscience provides us with a better understanding of how people become addicte ...
Efficacy, safety and tolerability of linezolid containing regimens in treating MDR-TB
Efficacy, safety and tolerability of linezolid containing regimens in treating MDR-TB

... restricted to case reports and small case series including both non-tuberculous mycobacterial diseases and TB [22–29]. Due to the lack of available antibiotics to treat such difficult cases, linezolid is already used off-label to treat MDR-TB in several countries, despite the absence of randomised c ...
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Pharmaceutical industry



The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.
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