Martindale: The Complete Drug Reference
... and the problem, now dubbed fibrosing colonopathy, was reviewed.7,8 Fibrosing colonopathy has also been reported9 in an adult who was not thought to have cystic fibrosis, but who had been taking high doses of pancreatic enzyme supplements, including 2 with methylacrylic acid copolymer (MAC) coatings ...
... and the problem, now dubbed fibrosing colonopathy, was reviewed.7,8 Fibrosing colonopathy has also been reported9 in an adult who was not thought to have cystic fibrosis, but who had been taking high doses of pancreatic enzyme supplements, including 2 with methylacrylic acid copolymer (MAC) coatings ...
PDF full-Text - Journal of Investigational Allergology and Clinical
... NSAID that inhibits COX-1 in all patients only induces an acute increase in CysLT in those with respiratory symptoms. In inflammatory conditions, arachidonic acid is oxidized by 5-lipoxygenase (5-LO) to leukotriene (LT) A4, which is metabolized into the final metabolite LTE4. Baseline levels of CysL ...
... NSAID that inhibits COX-1 in all patients only induces an acute increase in CysLT in those with respiratory symptoms. In inflammatory conditions, arachidonic acid is oxidized by 5-lipoxygenase (5-LO) to leukotriene (LT) A4, which is metabolized into the final metabolite LTE4. Baseline levels of CysL ...
March 2015 - Positive Recommendations
... The PBAC recommended the listing of Hexaxim on the National Immunisation Program for the primary vaccination series against diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis and invasive infections caused by Haemophilus influenzae type b at 2, 4 and 6 months of age, on a costminimisation ba ...
... The PBAC recommended the listing of Hexaxim on the National Immunisation Program for the primary vaccination series against diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis and invasive infections caused by Haemophilus influenzae type b at 2, 4 and 6 months of age, on a costminimisation ba ...
05_chapter 1
... performance and are integral component of the drug formulation. They can also serve various therapeutic-enhancing purposes such as facilitating drug absorption or solubility or other pharmacokinetic considerations [Lesney, 2001]. The selection of the excipients for a particular dosage form is very c ...
... performance and are integral component of the drug formulation. They can also serve various therapeutic-enhancing purposes such as facilitating drug absorption or solubility or other pharmacokinetic considerations [Lesney, 2001]. The selection of the excipients for a particular dosage form is very c ...
The role of pharmacoepidemiological studies in the market
... 1) supplement the information available from premarketing studies, giving a better quantification of the beneficial effects of the drug and incidence of known adverse events. 2) provide new information, such as identification of previously unknown adverse and beneficial effects, the effect of drug o ...
... 1) supplement the information available from premarketing studies, giving a better quantification of the beneficial effects of the drug and incidence of known adverse events. 2) provide new information, such as identification of previously unknown adverse and beneficial effects, the effect of drug o ...
Chapter-3 Drug and excipients profile
... magnesium hydroxide carries away much of the body's supply of potassium, and failure to take extra potassium may lead to muscle cramps. Magnesium hydroxide is also used as an antiperspirant armpit deodorant. Milk of magnesia is useful against canker sores (aphthous ulcer) when used topically. Milk o ...
... magnesium hydroxide carries away much of the body's supply of potassium, and failure to take extra potassium may lead to muscle cramps. Magnesium hydroxide is also used as an antiperspirant armpit deodorant. Milk of magnesia is useful against canker sores (aphthous ulcer) when used topically. Milk o ...
Making sense of itraconazole pharmacokinetics
... even severe mucositis and the concomitant use of H2 antagonists did not appear to reduce these levels significantly in the adult chemotherapy or transplant patients. In the children at day 14 however, levels of hydroxy-itraconazole were much higher than those of the parent drug with Cmin at 437 – 24 ...
... even severe mucositis and the concomitant use of H2 antagonists did not appear to reduce these levels significantly in the adult chemotherapy or transplant patients. In the children at day 14 however, levels of hydroxy-itraconazole were much higher than those of the parent drug with Cmin at 437 – 24 ...
FORMULATION AND CHARACTERIZATION OF MATRIX AND TRIPLE LAYER MATRIX
... The composition of formulation used in the study containing 100mg of Tramadol HCL in each case is shown in table 1. The granules were compressed using a rotary compression machine. (Riddhi, Ahmedabad, India). The triple layer matrix tablets were prepared by using different tramadol HCL polymers of i ...
... The composition of formulation used in the study containing 100mg of Tramadol HCL in each case is shown in table 1. The granules were compressed using a rotary compression machine. (Riddhi, Ahmedabad, India). The triple layer matrix tablets were prepared by using different tramadol HCL polymers of i ...
Enhancement of Taste Masking by A newly
... Ciprofloxacin HCl is one of several oral pharmaceuticals having unpleasant, bitter‐ taste characteristics. Thus, development of a newly formulated ciprofloxacin HCl oral dosage product with a pleasant taste would definitely be preferred in giving a unique identity to the product and adding value/tim ...
... Ciprofloxacin HCl is one of several oral pharmaceuticals having unpleasant, bitter‐ taste characteristics. Thus, development of a newly formulated ciprofloxacin HCl oral dosage product with a pleasant taste would definitely be preferred in giving a unique identity to the product and adding value/tim ...
Frequently Asked Questions
... In the case of wet granulation formulations, it is recommended to incorporate the polymer in the powder blend (0.5 - 3.0% w/w) versus adding it as an aqueous dispersion due to the high viscosity of the polymer. Carbopol® polymer dispersions (maximum 1%) can be used for fluid bed granulation. 17. Wh ...
... In the case of wet granulation formulations, it is recommended to incorporate the polymer in the powder blend (0.5 - 3.0% w/w) versus adding it as an aqueous dispersion due to the high viscosity of the polymer. Carbopol® polymer dispersions (maximum 1%) can be used for fluid bed granulation. 17. Wh ...
Text
... biological effect on the hamster flank organs may require systemic drug delivery rather than a liposome-mediated localized effect. The deposition of hydrocortisone into human skin was significantly higher after application of phosphatidylcholine (PC)/CH liposomes compared with an emulsion ointment ...
... biological effect on the hamster flank organs may require systemic drug delivery rather than a liposome-mediated localized effect. The deposition of hydrocortisone into human skin was significantly higher after application of phosphatidylcholine (PC)/CH liposomes compared with an emulsion ointment ...
Hard Shell Capsules
... shell capsule filling machines have the same operational steps in common: rectification, capsule separation, filling, closure of the capsule, and ejection of the filled and closed capsule from the machine. Rectification is a mechanical process that causes the empty capsules to be lined up all in the ...
... shell capsule filling machines have the same operational steps in common: rectification, capsule separation, filling, closure of the capsule, and ejection of the filled and closed capsule from the machine. Rectification is a mechanical process that causes the empty capsules to be lined up all in the ...
Biol. Pharm. Bull. 34(8): 1179
... In this study, a novel liquid self-emulsifying drug delivery system (SEDDS) containing curcumin was formulated and further developed into a solid form by a spray drying method using Aerosil 200 as the solid carrier. The optimum liquid SEDDS consisted of Lauroglycol Fcc, Labrasol and Transcutol HP as ...
... In this study, a novel liquid self-emulsifying drug delivery system (SEDDS) containing curcumin was formulated and further developed into a solid form by a spray drying method using Aerosil 200 as the solid carrier. The optimum liquid SEDDS consisted of Lauroglycol Fcc, Labrasol and Transcutol HP as ...
Adverse Health Effects of Marijuana Use
... the evidence clearly indicates that long-term marijuana use can lead to addiction. Indeed, approximately 9% of those who experiment with marijuana will become addicted3 (according to the criteria for dependence in the Diagnostic and Statistical Manual of Mental Disorders, 4th edition [DSM-IV]). The ...
... the evidence clearly indicates that long-term marijuana use can lead to addiction. Indeed, approximately 9% of those who experiment with marijuana will become addicted3 (according to the criteria for dependence in the Diagnostic and Statistical Manual of Mental Disorders, 4th edition [DSM-IV]). The ...
DRUG NAME: Hydroxyurea
... eruptions with erythema, vesicle formation, and desquamation of the skin. Reactions range in intensity from a mild rash to severe skin necrosis. Topical corticosteroids have been used to treat the dermatitis.16 Hyperuricemia may result from cell lysis by cytotoxic chemotherapy and may lead to electr ...
... eruptions with erythema, vesicle formation, and desquamation of the skin. Reactions range in intensity from a mild rash to severe skin necrosis. Topical corticosteroids have been used to treat the dermatitis.16 Hyperuricemia may result from cell lysis by cytotoxic chemotherapy and may lead to electr ...
Paclitaxel-coated Angioplasty Catheters for Local Drug Delivery
... compared with the total vessel area inside the stent struts, determined by histomorphometry four weeks after the intervention. Control = no drug; CM Pac = paclitaxel in contrast medium; Paccocath = paclitaxel-coated percutaneous transluminal coronary angioplasty balloons; Cypher = sirolimus-coated s ...
... compared with the total vessel area inside the stent struts, determined by histomorphometry four weeks after the intervention. Control = no drug; CM Pac = paclitaxel in contrast medium; Paccocath = paclitaxel-coated percutaneous transluminal coronary angioplasty balloons; Cypher = sirolimus-coated s ...
4 Alpha blockers
... The term alpha blockers covers a range of drugs, but for the purposes of this section it is primarily used to describe the selective alpha blockers that are mainly used for managing hypertension and benign prostatic hyperplasia. Other drugs that have alpha-blocking actions are covered elsewhere in t ...
... The term alpha blockers covers a range of drugs, but for the purposes of this section it is primarily used to describe the selective alpha blockers that are mainly used for managing hypertension and benign prostatic hyperplasia. Other drugs that have alpha-blocking actions are covered elsewhere in t ...
Mifepristone: Expanding Women`s Options for Early Abortion in the
... • An overwhelming majority of women who choose mifepristone for medication abortion are satisfied with the method. One study found that 97 percent of women would recommend the method to a friend. Additionally, 91 percent of the women reported that they would choose the mifepristone regimen again i ...
... • An overwhelming majority of women who choose mifepristone for medication abortion are satisfied with the method. One study found that 97 percent of women would recommend the method to a friend. Additionally, 91 percent of the women reported that they would choose the mifepristone regimen again i ...
How to Protect Yourself Against Malaria
... microscopic crystals, made surfaces lethal to mosquitoes for months. But, although this residual insecticide reversed the odds in the struggle, within a few years the Anopheles had developed a resistance to these chemicals. Other pesticides followed, always with the same inglorious result. Today, ma ...
... microscopic crystals, made surfaces lethal to mosquitoes for months. But, although this residual insecticide reversed the odds in the struggle, within a few years the Anopheles had developed a resistance to these chemicals. Other pesticides followed, always with the same inglorious result. Today, ma ...
Updating the List
... www.rpharms.com/law-and-ethics/medicinesethics-and-practice-guide.asp Only free to RPS members. ...
... www.rpharms.com/law-and-ethics/medicinesethics-and-practice-guide.asp Only free to RPS members. ...
Clinical relevance of the small intestine as an organ of
... some of these diet-derived xenobiotics may be capable of modulating drug metabolism in a manner similar to therapeutic agents [18,191. Therefore, inhibition of drug metabolism by dietary substances could lead to increased concentrations of the target drug and the potential for an exaggerated pharmac ...
... some of these diet-derived xenobiotics may be capable of modulating drug metabolism in a manner similar to therapeutic agents [18,191. Therefore, inhibition of drug metabolism by dietary substances could lead to increased concentrations of the target drug and the potential for an exaggerated pharmac ...
System-Wide Medication Related Decision Evaluation
... old) of Providence Health Plan. This review of utilization is subsequent to action taken by Providence Health and Services to restrict use of codeine for pediatrics in acute settings. Providence Health & Services implemented a pediatric codeine interchange in the Providence Epic system acute envir ...
... old) of Providence Health Plan. This review of utilization is subsequent to action taken by Providence Health and Services to restrict use of codeine for pediatrics in acute settings. Providence Health & Services implemented a pediatric codeine interchange in the Providence Epic system acute envir ...
DEVELOPMENT AND VALIDATION OF A REVERSE PHASE HPLC METHOD FOR
... cholesterol, LDL cholesterol, apolipoprotien B, Total triglyceride and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increase in high density lipoprotein (HDL) and apoprotiens apo AI and apo AII4. Several studies have shown that therapeu ...
... cholesterol, LDL cholesterol, apolipoprotien B, Total triglyceride and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increase in high density lipoprotein (HDL) and apoprotiens apo AI and apo AII4. Several studies have shown that therapeu ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.