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Pregnancy, Breast-feeding, and Marijuana
Pregnancy, Breast-feeding, and Marijuana

... poor visual habituation, which resolved within a few days of birth.39,41 This study relied on maternal report of marijuana use, and there was no mention of testing for use of additional drugs such as heroin or prescription narcotics. In both of the studies from Jamaica and Colorado, the cohorts were ...
Windtree Therapeutics (WINT)
Windtree Therapeutics (WINT)

... Surfactants, which are small peptide-lipid mixtures that help the lungs fill easily and maintain their shape upon exhalation, do not begin to form in the lungs until very late in the gestation period. RDS was a leading cause of death among premature infants before the introduction of surfactants via ...
Vemlidy - Gilead
Vemlidy - Gilead

... glucose, and urine protein is recommended before initiating VEMLIDY therapy and during therapy as clinically appropriate. (5.3) • Lactic acidosis/severe hepatomegaly with steatosis: Discontinue treatment in patients who develop symptoms or laboratory findings suggestive of lactic acidosis or pronoun ...
Pharmacotherapy Treatment Options for Insomnia
Pharmacotherapy Treatment Options for Insomnia

... to benzodiazepines. Like benzodiazepines, these drugs are safe regarding overdoses. In contrast, dependence and withdrawal symptoms rarely develop with some believing that this is related to its specificity at the GABA-A receptor described above [30]. In addition, non-benzodiazepines tend not to be ...
Vaccines: `Safest of Medicines` or the `Biggest Lie`
Vaccines: `Safest of Medicines` or the `Biggest Lie`

... vaccine, and c) the added medical costs of the vaccination program would be offset by the reduced societal costs (if lost work time) incurred when parents cared for their sick children. When the actual experience showed that onedose protected less than 60% of those inoculated from getting chickenpox ...
ANTICONVULSANT ACTIVITY OF AQUEOUS ROOT EXTRACT OF CALOTROPIS GIGANTEA IN
ANTICONVULSANT ACTIVITY OF AQUEOUS ROOT EXTRACT OF CALOTROPIS GIGANTEA IN

... family “Asclepediaceae ” is traditionally being used to cure various diseases such as fever, rheumatism, indigestion, cough, cold, eczema, asthma, elephantiasis, nausea, vomiting, diarrhea. Calotropis gigantea also called as ‘Milkweed’ is a common wasteland weed distributed in tropical and subtropic ...
Lactic acid- and carbonate-based crosslinked polymeric micelles for drug delivery.
Lactic acid- and carbonate-based crosslinked polymeric micelles for drug delivery.

... improve micelle stability through p–p interactions as demonstrated by decreased CMC values.12 In practice, physically stabilized micelles are limited by their inability to prevent micelle destabilization caused by blood components. In contrast, introduction of chemical covalent crosslinks into the s ...
Soluble guanylate cyclase stimulators as a potential
Soluble guanylate cyclase stimulators as a potential

... imaging end-points, going beyond single-centre phase II trials. In summary, GRIMMINGER et al. [2] should be congratulated for their efficient animal-to-human translational work. The scientists at Bayer should be proud that they have discovered amazing and powerful drugs which could have a significan ...
Seizure
Seizure

...  Goal—maximize quality of life by minimizing seizures and adverse drug effects  Currently no “anti-epileptogenic” drugs available ...
Expert peer review No.1  Agenda item 6.1: Tramadol 
Expert peer review No.1  Agenda item 6.1: Tramadol 

... ….tramadol has a low abuse potential relative to the prototypic morphine”.  ...
Pharmacokinetics of Antimony in Children Treated for Leishmaniasis
Pharmacokinetics of Antimony in Children Treated for Leishmaniasis

... WinNonLin Professional software (version 5.0; Pharsight). Values for half-life(b) and apparent volume of distribution [Vd/ F(b)] were calculated from the elimination rate constants associated with the log-linear portions of the time-concentration curves. Renal clearance was calculated as ClR p [Sb]U ...
SNRIs: an approach - Psychopharmacology Institute
SNRIs: an approach - Psychopharmacology Institute

... Thase,M “Mirtazapine”, in Kaplan and Sadock's Comprehensive Textbook of Psychiatry. 9th ed. Philadelphia: Lippincott Williams & Wilkins, ...
DRUG NAME: Octreotide  SYNONYM(S): COMMON TRADE NAME(S):
DRUG NAME: Octreotide SYNONYM(S): COMMON TRADE NAME(S):

... long-term octreotide should be assessed with ultrasound of the gallbladder and bile ducts every 6-12 months.4 Gallstones usually respond to chenodeoxycholic acid or ursodeoxycholic acid. Interruption or discontinuation of octreotide may be considered based on the risk-benefit ratio of the patient.9 ...
How to Protect Yourself Against Malaria
How to Protect Yourself Against Malaria

... microscopic crystals, made surfaces lethal to mosquitoes for months. But, although this residual insecticide reversed the odds in the struggle, within a few years the Anopheles had developed a resistance to these chemicals. Other pesticides followed, always with the same inglorious result. Today, ma ...
What the pulmonary specialist should know about the new
What the pulmonary specialist should know about the new

... need to master specific inhalation techniques, which require varying levels of cognitive ability depending on the device. Reviews of randomised controlled trials comparing different inhalers have concluded that they are all equivalent [6, 7]. However, patients in randomised controlled trials receive ...
O A
O A

... of different commercial brands of butamirate citrate (tablets and syrups) and satisfactory results were obtained. The method is selective, sensitive, accurate, precise, rugged and robust. Thus the method can be used for the routine analysis of butamirate citrate in pharmaceutical preparations. Key w ...
MMIC PA Guidelines
MMIC PA Guidelines

... Aetna Medicaid requires use of generic agents that are considered therapeutically equivalent by the FDA. For authorization of a brand name medication, please submit a copy of the FDA MedWatch form detailing trial and failure of, or intolerance/adverse side effect to generic formulations made by 2 di ...
Antibody–drug conjugates nonclinical support: from early to late
Antibody–drug conjugates nonclinical support: from early to late

... Depending on the linker lability and ADC stability, the processing of serum may cause deconjugation and release of cytotoxic small molecule drug that may interfere in quantitation of small molecule analyte of some ADCs. The plasma matrix is thus preferred for LC–MS-based quantitation of the antibody ...
2.7.3 Emulgent-free nanoporous/nanoparticulate
2.7.3 Emulgent-free nanoporous/nanoparticulate

... The preparation of coated particles involving several production steps, such as those used by Pilcer et al. [10] and Raula et al. [11], might not be advantageous for industrial production. Therefore a coated particle technology, based on a one-step process of microparticle formation from drug/L-leuc ...
SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE
SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE

... Methylthioninium Chloride EmBlue is primarily used in the treatment of druginduced and genetic methaemoglobinaemia that are not due to a structural abnormality of haemoglobin. ...
Emerging Issues In The Use Of Methadone
Emerging Issues In The Use Of Methadone

... arrhythmic properties of methadone was presented. This meeting was reconvened on July 20, 2007, and titled Methadone Mortality—A Reassessment. One action that emerged was formation of a multi­ disciplinary expert panel on the cardiac effects of methadone, charged with formulating a clinical practice ...
analgesic nephropathy medical grand rounds william
analgesic nephropathy medical grand rounds william

... § Si~niCicantly different when 7 patients with diabetic renal disease were removed from the control population. I Cunaumers of aspirin alone or phenacetin -free compounds except whe~ indicated. ...
Comparison of the antidepressants reboxetine
Comparison of the antidepressants reboxetine

... waves was paralleled by the failure of this drug to affect subjectively rated alertness. In fact, the only effect of this drug on the visual analogue scales was a small reduction in “anxiety”. As reboxetine is a selective and potent noradrenaline reuptake inhibitor (Brunello and Racagni 1998), it mi ...
REVIEW Arrhythmic risk biomarkers for the assessment of
REVIEW Arrhythmic risk biomarkers for the assessment of

... Wasserstrom 1988). However, it also blocks the calcium current and a variety of potassium conductances. Its class III effects on IKr have been suggested as the reason for its pro-arrhythmic potential (Yang & Roden 1996). Quinidine was found to increase ERP in a rate-independent manner in humans (Ros ...
PROPOSAL FOR THE INCLUSION OF RISPERIDONE FOR THE
PROPOSAL FOR THE INCLUSION OF RISPERIDONE FOR THE

... on the public health relevance of schizophrenia, as significantly better epidemiological data exists for schizophrenia compared with that of other psychotic disorders. Schizophrenia is a significant contributor to the global disease burden, accounting for 1.1% of disability-adjusted life years (DAL ...
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The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.
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