IMMUNOMEDICS` UNLABELED CEA ANTIBODY INHIBITS HUMAN
... announced that preclinical studies involving its proprietary unlabeled antibody, which targets carcinoembryonic antigen (CEA), demonstrated anti-tumor activity in animals with a human tumor transplant. Further preclinical and clinical studies of both the unlabeled and radiolabeled forms of this anti ...
... announced that preclinical studies involving its proprietary unlabeled antibody, which targets carcinoembryonic antigen (CEA), demonstrated anti-tumor activity in animals with a human tumor transplant. Further preclinical and clinical studies of both the unlabeled and radiolabeled forms of this anti ...
Optical Isomerism
... Chiral Pool Synthesis: this uses naturally occurring chiral molecules within the synthetic route such as α-amino acids and sugars. Using transition element complexes to produce chiral catalysts which could transfer their chirality to produce a single isomer ...
... Chiral Pool Synthesis: this uses naturally occurring chiral molecules within the synthetic route such as α-amino acids and sugars. Using transition element complexes to produce chiral catalysts which could transfer their chirality to produce a single isomer ...
FREE Sample Here
... Intrinsic drugs are the hormones, enzymes, and other chemicals made by the body that change cell activity. Extrinsic drugs are manufactured from chemical, animal, or plant sources and must have a means of entering the body in order to change cell activity. PTS: 1 DIF: Cognitive Level: Understanding ...
... Intrinsic drugs are the hormones, enzymes, and other chemicals made by the body that change cell activity. Extrinsic drugs are manufactured from chemical, animal, or plant sources and must have a means of entering the body in order to change cell activity. PTS: 1 DIF: Cognitive Level: Understanding ...
Setting the scene - WHO archives
... Increased understanding of germs and bacteria led to the development of compounds, which could kill bacteria and cure disease. (Salvarsan, an arsenic compound, was synthesised in 1910 and used to treat syphilis). Penicillin was identified in 1928 but not really recognised until 1939 when it ushered ...
... Increased understanding of germs and bacteria led to the development of compounds, which could kill bacteria and cure disease. (Salvarsan, an arsenic compound, was synthesised in 1910 and used to treat syphilis). Penicillin was identified in 1928 but not really recognised until 1939 when it ushered ...
Drug concentration
... • When HIV reproduces - it makes mistakes - so new virus is not exactly the same • Most of these changes do not matter, but some will stop HIV drugs from working • Resistance only develops when you are taking treatment with a detectable viral load • Main cause of resistance is poor adherence HIV i-B ...
... • When HIV reproduces - it makes mistakes - so new virus is not exactly the same • Most of these changes do not matter, but some will stop HIV drugs from working • Resistance only develops when you are taking treatment with a detectable viral load • Main cause of resistance is poor adherence HIV i-B ...
Introduction to Tolerance, Physical Dependence and Withdrawal
... • Dependence can be part of addiction, but is not the same thing • Psychological dependence – Drug/substance abuse, addiction, craving, relapse (key element is emotional need) a: American Academy of Pain Medicine, American Pain Society, American Society of Addiction Medicine definition ...
... • Dependence can be part of addiction, but is not the same thing • Psychological dependence – Drug/substance abuse, addiction, craving, relapse (key element is emotional need) a: American Academy of Pain Medicine, American Pain Society, American Society of Addiction Medicine definition ...
Slide set - Perelman School of Medicine at the University of
... children are enrolled only after a prospect of direct benefit is demonstrated first in the adult population • If there are no adults with a disease or condition, the pre-clinical data in vitro and in animals in vivo are optimally sufficient to support a first study in children • First-in-children ...
... children are enrolled only after a prospect of direct benefit is demonstrated first in the adult population • If there are no adults with a disease or condition, the pre-clinical data in vitro and in animals in vivo are optimally sufficient to support a first study in children • First-in-children ...
Antibiotics in Dentistry
... completion is the KEY issue in their effectiveness. He cites a study in which less than 50% of patients complied with taking Pen VK 500mg qid but over 75% complied taking amoxicillin 875mg bid. Patients can better remember to take their medication when only required to do so twice a day. Therefore, ...
... completion is the KEY issue in their effectiveness. He cites a study in which less than 50% of patients complied with taking Pen VK 500mg qid but over 75% complied taking amoxicillin 875mg bid. Patients can better remember to take their medication when only required to do so twice a day. Therefore, ...
Lecture 5 V- Parenteral administration
... 2) With orally administrated prolonged – release drug products, erratic or variable drug absorption might occur due to the various interactions of drug with the contents of GI tract and the change of GI motility. 3) The formulation of prolonged release drug products for drugs usually given in large ...
... 2) With orally administrated prolonged – release drug products, erratic or variable drug absorption might occur due to the various interactions of drug with the contents of GI tract and the change of GI motility. 3) The formulation of prolonged release drug products for drugs usually given in large ...
to view a pdf version of EyeWorld Week
... and Refractive Surgery and the American Society of Ophthalmic Administrators, is published every Friday, distributed by email, and posted live on Friday. ...
... and Refractive Surgery and the American Society of Ophthalmic Administrators, is published every Friday, distributed by email, and posted live on Friday. ...
Plasma Concentration - University of Nebraska Medical Center
... Remember for most drugs you are very low on the place of rate of elimination versus drug concentration – Note: Induction or inhibition of a CYP 450 isozyme will affect the metabolism of all drugs metabolized by that isozyme ...
... Remember for most drugs you are very low on the place of rate of elimination versus drug concentration – Note: Induction or inhibition of a CYP 450 isozyme will affect the metabolism of all drugs metabolized by that isozyme ...
A letter from the CEO Letter v17-1.pages
... for HSV-1 and HSV-2, their effectiveness is limited. Effective control of herpesviruses will require drugs with a different mechanism of action than this existing nucleoside class of drugs. Some for these nucleoside drugs are also approved for treatment of shingles, but they have extremely limited e ...
... for HSV-1 and HSV-2, their effectiveness is limited. Effective control of herpesviruses will require drugs with a different mechanism of action than this existing nucleoside class of drugs. Some for these nucleoside drugs are also approved for treatment of shingles, but they have extremely limited e ...
Why Herb Products Rather Than Single Compounds?
... “The time is yet far distant when we can depend upon active principles alone for the curative treatment of disease. The complex of constituents represented by the whole drug substance or a tincture or extract of it cannot be dispensed with. … This latter day tendency to administer attenuated doses o ...
... “The time is yet far distant when we can depend upon active principles alone for the curative treatment of disease. The complex of constituents represented by the whole drug substance or a tincture or extract of it cannot be dispensed with. … This latter day tendency to administer attenuated doses o ...
Pharmaceutical Dosage Forms
... • API can be degraded at the site of administration (e.g., low pH in stomach) • API may cause local irritations or injury when they are present at high concentrations at the site of administration • API can have unpleasant organoleptic qualities (taste, smell – compliance!) • Administration of activ ...
... • API can be degraded at the site of administration (e.g., low pH in stomach) • API may cause local irritations or injury when they are present at high concentrations at the site of administration • API can have unpleasant organoleptic qualities (taste, smell – compliance!) • Administration of activ ...
journal - Breining Institute
... The leading health problem that plagues our society is drug and alcohol use, and the related abuse and addiction. From caffeine to nicotine to illegal drugs, throughout history people have always used some type of mood- or mind-altering chemical for pleasure, as well as plant extracts and narcotics ...
... The leading health problem that plagues our society is drug and alcohol use, and the related abuse and addiction. From caffeine to nicotine to illegal drugs, throughout history people have always used some type of mood- or mind-altering chemical for pleasure, as well as plant extracts and narcotics ...
Merck Global Security
... as well – yet slowing down the counterfeiters in China and elsewhere will take heroic efforts…Counterfeiting thrives on…globalization itself. Globalization is the spread of capital and know how to new markets.” ...
... as well – yet slowing down the counterfeiters in China and elsewhere will take heroic efforts…Counterfeiting thrives on…globalization itself. Globalization is the spread of capital and know how to new markets.” ...
ANTIPSYCHOTIC DRUGS & LITHIUM
... Tend to develop after years of therapy May appear as early as 6 months ...
... Tend to develop after years of therapy May appear as early as 6 months ...
Alcohol and Drug Abuse
... cramps, nausea, faintness, chills, sweating, and blurred vision. – High doses can interfere with the ability to regulate body temperature, resulting in a sharp increase in body temperature (hyperthermia), leading to liver, kidney and cardiovascular failure. – Severe dehydration can result from the c ...
... cramps, nausea, faintness, chills, sweating, and blurred vision. – High doses can interfere with the ability to regulate body temperature, resulting in a sharp increase in body temperature (hyperthermia), leading to liver, kidney and cardiovascular failure. – Severe dehydration can result from the c ...
Outpatient prescriptions practice and writing quality in a paediatric
... In our study the number of errors more than doubled between 2005 and 2010. One third of such errors were caused by changes in marketed medicines, some being withdrawn or having changed their trade name. The increase could also be due to the fast turnover of junior physicians, to their more important ...
... In our study the number of errors more than doubled between 2005 and 2010. One third of such errors were caused by changes in marketed medicines, some being withdrawn or having changed their trade name. The increase could also be due to the fast turnover of junior physicians, to their more important ...
DRUGS
... • They must use samples that have been extracted from bodily fluids and organs for testing. The amounts of the drugs may be very small ...
... • They must use samples that have been extracted from bodily fluids and organs for testing. The amounts of the drugs may be very small ...
Aerosols
... Definition: The term aerosol is used to denote various systems ranging from those of a colloidal nature to systems consisting of pressurized packages. Aerosols have been defined as colloidal systems consisting of very finely subdivided liquid or solid particles dispersed in and surrounded by a ...
... Definition: The term aerosol is used to denote various systems ranging from those of a colloidal nature to systems consisting of pressurized packages. Aerosols have been defined as colloidal systems consisting of very finely subdivided liquid or solid particles dispersed in and surrounded by a ...
Slide 1
... assess the significance of potential drug-herb interactions, in particularly cardiovascular drugs – herbs interactions ...
... assess the significance of potential drug-herb interactions, in particularly cardiovascular drugs – herbs interactions ...
view presentation - Pacira Pharmaceuticals, Inc.
... • Improved dosing and administration – weekly and monthly profiles to improve PK/PD • Three active partnerships for multiple products and combinations of products – subcutaneous dosing • DepoFoam® provides a novel opportunity for long acting intrathecal injection for Multiple Sclerosis, Alzheimer's, ...
... • Improved dosing and administration – weekly and monthly profiles to improve PK/PD • Three active partnerships for multiple products and combinations of products – subcutaneous dosing • DepoFoam® provides a novel opportunity for long acting intrathecal injection for Multiple Sclerosis, Alzheimer's, ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.