e History of 5-ASA Compounds and their Use in Ulcerative Colitis
... of this condition [9]. With its role as a long-term preventive treatment the problem of side effects became one of the driving factors behind the search for which part of the molecule was responsible for sulfasalazine’s anti-inflammatory activity. This search identified 5 aminosalicylate (Mesalazine ...
... of this condition [9]. With its role as a long-term preventive treatment the problem of side effects became one of the driving factors behind the search for which part of the molecule was responsible for sulfasalazine’s anti-inflammatory activity. This search identified 5 aminosalicylate (Mesalazine ...
Treatment of tuberculosis in renal disease
... 7. The treatment of TB in patients with mild renal impairment, and with glomerular filtration rate (GFR) between 30-60ml/min, should be individualised using standard drugs in dose ranges in the lower range of usual recommendations for patients with normal renal function, with careful monitoring of s ...
... 7. The treatment of TB in patients with mild renal impairment, and with glomerular filtration rate (GFR) between 30-60ml/min, should be individualised using standard drugs in dose ranges in the lower range of usual recommendations for patients with normal renal function, with careful monitoring of s ...
Module 3. Pharmaceutical care during OTC medications vacation
... 18. Which drug decreases the demand in oxygen due to the blockade of the sympathetic innervation? A. Molsidomin B. * Atenolol C. Pentoxiphylline D. Papaverinum E. Nitroglycerine 19. An efficiency of beta-adrenoblockers at angina pectoris is explained by A. * The removal of the sympathetic influences ...
... 18. Which drug decreases the demand in oxygen due to the blockade of the sympathetic innervation? A. Molsidomin B. * Atenolol C. Pentoxiphylline D. Papaverinum E. Nitroglycerine 19. An efficiency of beta-adrenoblockers at angina pectoris is explained by A. * The removal of the sympathetic influences ...
Vioxx
... 7. What evidence supports the Public Health Advisory? Merck’s decision to withdraw Vioxx from the market is based on new data from a trial called the APPROVe [ Adenomatous Polyp Prevention on VIOXX] trial. In the APPROVe trial, Vioxx was compared to placebo (sugar-pill). The purpose of the trial wa ...
... 7. What evidence supports the Public Health Advisory? Merck’s decision to withdraw Vioxx from the market is based on new data from a trial called the APPROVe [ Adenomatous Polyp Prevention on VIOXX] trial. In the APPROVe trial, Vioxx was compared to placebo (sugar-pill). The purpose of the trial wa ...
1
... deaminase [16] is indicated for patients with severe combined immunodefficiency disease. PEG modified L-asparaginase [17] is indicated for patients with acute lymphoblastic leukemia who require L-asparaginase in their treatment regimen, but are hypersensitive to the native forms of L-asparaginase. P ...
... deaminase [16] is indicated for patients with severe combined immunodefficiency disease. PEG modified L-asparaginase [17] is indicated for patients with acute lymphoblastic leukemia who require L-asparaginase in their treatment regimen, but are hypersensitive to the native forms of L-asparaginase. P ...
DRUGS INFLUENCING COGNITIVE FUNCTION
... the last decade. Nootropics are defined as drugs that generally increase neuron metabolic activity, improve cognitive and vigilance level and are said to have antidementia effect (1). These drugs are essential for the treatment of geriatric disorders like Alzheimer's which have become one of the maj ...
... the last decade. Nootropics are defined as drugs that generally increase neuron metabolic activity, improve cognitive and vigilance level and are said to have antidementia effect (1). These drugs are essential for the treatment of geriatric disorders like Alzheimer's which have become one of the maj ...
Delivery Mechanisms - WHO archives
... fixed dose combinations (FDCs) as an innovative delivery mechanism in this context, even though FDCs may be useful to improve adherence and can simplify procurement, storage and distribution of medicines. There are a variety of reasons for this reluctance (See Section 3). However, FDCs are an import ...
... fixed dose combinations (FDCs) as an innovative delivery mechanism in this context, even though FDCs may be useful to improve adherence and can simplify procurement, storage and distribution of medicines. There are a variety of reasons for this reluctance (See Section 3). However, FDCs are an import ...
FORMULATION AND EVALUATION OF OFLOXACIN FLOATING TABLETS USING HPMC Research Article
... buoyant tablets) were prepared and evaluated to increase its local action and bioavailability. In the present study six formulations with variable concentration of polymer (HPMC) were prepared by wet granulation technique and evaluated for physicochemical properties, buoyancy l ...
... buoyant tablets) were prepared and evaluated to increase its local action and bioavailability. In the present study six formulations with variable concentration of polymer (HPMC) were prepared by wet granulation technique and evaluated for physicochemical properties, buoyancy l ...
presentation ( format)
... Overall conclusion from PLATO: In ACS patients, ticagrelor reduces cardiovascular endpoints with this benefit offset by non-procedure-related bleeding. Wallentin L, et al. NEJM 2009; 361:1045-57 ...
... Overall conclusion from PLATO: In ACS patients, ticagrelor reduces cardiovascular endpoints with this benefit offset by non-procedure-related bleeding. Wallentin L, et al. NEJM 2009; 361:1045-57 ...
Clinical experiences with cannabinoids in spasticity management in
... available drugs used to treat spasticity and associated symptoms (pain, rigidity, spasms, etc.) generally present limited effectiveness and are poorly tolerated.4,5 In fact, actual use of these treatments is quite low. In the 6E study, 57% of the patients with spasticity were not treated with any dr ...
... available drugs used to treat spasticity and associated symptoms (pain, rigidity, spasms, etc.) generally present limited effectiveness and are poorly tolerated.4,5 In fact, actual use of these treatments is quite low. In the 6E study, 57% of the patients with spasticity were not treated with any dr ...
CONTROLLED RELEASE OF A WATER SOLUBLE DRUG, METOPROLOL SUCCINATE, BY... LACTALBUMIN MICROPARTICLES
... The results obtained in this study is part of our research effort to synthesis α-lactalbumin microparticles which can accommodate range of drugs with varied physiochemical properties and also to study the effects of processing conditions on particles size, drug loading and sustained release. In the ...
... The results obtained in this study is part of our research effort to synthesis α-lactalbumin microparticles which can accommodate range of drugs with varied physiochemical properties and also to study the effects of processing conditions on particles size, drug loading and sustained release. In the ...
Pharmacologic Treatment Options for Obesity: What Is Old Is New Again
... and BLOSSOM [25•], enrolled volunteers who were obese or had BMI≥27 kg/m2 with one comorbidity. The third study, BLOOM DM [26•], enrolled diabetic patients with hemoglobin A1C 7–10 % and BMI 27–45 kg/m2. In this study, all patients (including the placebo group) received counseling in diet and physic ...
... and BLOSSOM [25•], enrolled volunteers who were obese or had BMI≥27 kg/m2 with one comorbidity. The third study, BLOOM DM [26•], enrolled diabetic patients with hemoglobin A1C 7–10 % and BMI 27–45 kg/m2. In this study, all patients (including the placebo group) received counseling in diet and physic ...
Pharmacology Definitions
... one of the methods mentioned above. The binding of an antagonist results in no response from the cell. The antagonist shows no selectivity for the activated state of the receptor and hence the receptor is not activated. Antagonists show affinity for the receptor binding site, having a complementary ...
... one of the methods mentioned above. The binding of an antagonist results in no response from the cell. The antagonist shows no selectivity for the activated state of the receptor and hence the receptor is not activated. Antagonists show affinity for the receptor binding site, having a complementary ...
The Vermont Legislative Research Shop Methadone
... Studies have found methadone maintenance programs are more effective than drug-free treatment in that they reduce: (1) illicit opiate use; (2) the risk of acquiring HIV associated with injection and; (3) criminal activity (Farrell et al., 1994). The reduction in drug use and crime are directly rela ...
... Studies have found methadone maintenance programs are more effective than drug-free treatment in that they reduce: (1) illicit opiate use; (2) the risk of acquiring HIV associated with injection and; (3) criminal activity (Farrell et al., 1994). The reduction in drug use and crime are directly rela ...
anxiolytics2011-09
... Clinical Uses: used for treating benzodiazepine overdose, in the reversal of deep sedative action of benzodiazepine when used during anesthesia, and to treat drowsiness and coma associated with alcohol intoxication and severe liver diseases such as hepatic encephalopathy Adverse Effects: associated ...
... Clinical Uses: used for treating benzodiazepine overdose, in the reversal of deep sedative action of benzodiazepine when used during anesthesia, and to treat drowsiness and coma associated with alcohol intoxication and severe liver diseases such as hepatic encephalopathy Adverse Effects: associated ...
EFFECT OF pH ON THE PARTITION CO
... produce a blue purple color complex with Folin- Ciocalteau reagent which consists of sodium tungstate molybdate and phosphate. It has maximum absorption in the region of 660 nm wavelength, thus the intensity of color depends on the amount of these aromatic amino acids present and will thus vary for ...
... produce a blue purple color complex with Folin- Ciocalteau reagent which consists of sodium tungstate molybdate and phosphate. It has maximum absorption in the region of 660 nm wavelength, thus the intensity of color depends on the amount of these aromatic amino acids present and will thus vary for ...
Adrenergic_antagonis..
... decrease in its own release and decrease sympathetic tone to blood vessels, leading to VD and decreased BP Which one of the above mechanism is more important for treating hypertension? Decreasing renin secretion ...
... decrease in its own release and decrease sympathetic tone to blood vessels, leading to VD and decreased BP Which one of the above mechanism is more important for treating hypertension? Decreasing renin secretion ...
quarterly news
... administration of codeine or morphine during delivery. Researchers at USDTL seized upon this knowledge to work to improve their ability to detect heroin exposure. They took a two-fold approach. First, they improved their method for detecting 6-MAM in umbilical cord tissue. The lowest concentration o ...
... administration of codeine or morphine during delivery. Researchers at USDTL seized upon this knowledge to work to improve their ability to detect heroin exposure. They took a two-fold approach. First, they improved their method for detecting 6-MAM in umbilical cord tissue. The lowest concentration o ...
EFFECTS OF MUCOADHESIVE POLYMERS COMBINATION ON THE PROPERTIES OF LISINPRIL
... from mucus membrane is called the mucoadhesive force and is represented in Newton [17]. Force of adhesion (N) = Mucoadhesive strength (g) / 100 X 9.81 In vitro drug release study The tablets were supposed to release the drug from one side only; therefore an impermeable backing membrane was placed on ...
... from mucus membrane is called the mucoadhesive force and is represented in Newton [17]. Force of adhesion (N) = Mucoadhesive strength (g) / 100 X 9.81 In vitro drug release study The tablets were supposed to release the drug from one side only; therefore an impermeable backing membrane was placed on ...
Griffin 460 Mobile GC/MS Analysis of Designer
... long-term toxicity or immediate physiological effects that are associated with these new designer drugs, because they aren’t necessarily associated with the original illicit drug that was replicated. Herbal incense and bath salt products have been linked to hospitalizations, episodes of psychotic be ...
... long-term toxicity or immediate physiological effects that are associated with these new designer drugs, because they aren’t necessarily associated with the original illicit drug that was replicated. Herbal incense and bath salt products have been linked to hospitalizations, episodes of psychotic be ...
Relevance of USP Methodology in the Development of a
... Hydrophilic matrices continue to be a growing area of interest to provide controlled drug delivery to the oral route. Factors that influence drug release through hydrophilic matrices have been extensively reviewed in the literature. Verapamil Hydrochloride (HCl) is a weakly basic drug which has been ...
... Hydrophilic matrices continue to be a growing area of interest to provide controlled drug delivery to the oral route. Factors that influence drug release through hydrophilic matrices have been extensively reviewed in the literature. Verapamil Hydrochloride (HCl) is a weakly basic drug which has been ...
Moving mountains to serve cancer patients
... Former President and CEO of Cornerstone Pharma. 25+ years of specialty pharmaceutical executive experience in Fortune 500 companies (BMS, Eli Lilly, J&J and GE) as well as biotech firms (Endo and Sunesis). ...
... Former President and CEO of Cornerstone Pharma. 25+ years of specialty pharmaceutical executive experience in Fortune 500 companies (BMS, Eli Lilly, J&J and GE) as well as biotech firms (Endo and Sunesis). ...
High-dose antipsychotic medication
... All known antipsychotic drugs are antagonists at D2receptors, but their selectivity and potency vary considerably. By 'selectivity' is meant the 'cleanliness' of their pharmacology - what receptors other than D2 receptors the drug might block. 'Potency' is a complex property, reflecting the bioavail ...
... All known antipsychotic drugs are antagonists at D2receptors, but their selectivity and potency vary considerably. By 'selectivity' is meant the 'cleanliness' of their pharmacology - what receptors other than D2 receptors the drug might block. 'Potency' is a complex property, reflecting the bioavail ...
printable PDF - Edison Investment Research
... Current marketed GLP-1 receptor agonists, including Victoza, are all injectable. C4XD has developed orally available activation compounds, which it believes will be both efficacious and have reduced side-effects. IL-17 IL-17 is implicated in multiple inflammatory and autoimmune diseases. Most produc ...
... Current marketed GLP-1 receptor agonists, including Victoza, are all injectable. C4XD has developed orally available activation compounds, which it believes will be both efficacious and have reduced side-effects. IL-17 IL-17 is implicated in multiple inflammatory and autoimmune diseases. Most produc ...
Treating Overactive Bladder in the Elderly: Side
... discontinuation by 1.5% of participants taking oxybutynin-ER and 0.5% of participants taking tolterodineER. It is worth mentioning that only 15% of the OPERA population were over 75 years of age. The study authors do not present a comparative analysis of these CNS side effects in this subpopulation, ...
... discontinuation by 1.5% of participants taking oxybutynin-ER and 0.5% of participants taking tolterodineER. It is worth mentioning that only 15% of the OPERA population were over 75 years of age. The study authors do not present a comparative analysis of these CNS side effects in this subpopulation, ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.