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Intranasal medications and doses
Intranasal medications and doses

... Always deliver half the medication dose up each nostril. This doubles the available mucosal surface area (over a single nostril) for drug absorption and increases rate and amount of absorption. ...
Therapeutic Drug Monitoring in the Geriatric Patient
Therapeutic Drug Monitoring in the Geriatric Patient

... A higher incidence of diarrhea and a delay in onset action of weakly basic drugs also result from this physiologic effect. One study reported a three-fold decrease in levodopa availability in the elderly because delayed gastric emptying allowed the increased degradation by GI dopa-decarboxylase to d ...
Evidence-based treatment for drug misuse, with special reference to
Evidence-based treatment for drug misuse, with special reference to

... Some of the issues identified here may be a cause for concern, and these include: the complex gabapentinoid pharmacodynamics, possibly including the involvement of drug reward pathways; the increasing prescription levels over time ...
Legal, Ethical and Regulatory Aspects of Introducing Emergency
Legal, Ethical and Regulatory Aspects of Introducing Emergency

... often been neglected by regulatory bodies and health service personnel. In the case of emergency contraception, where existing methods are used for a different yet important purpose, would women suffer discomfort, side effects or any other consequences because of the larger doses or changes in the m ...
Name  ______________________________  CH 204, Fall 2014 Assignment 8 – Opioids
Name ______________________________ CH 204, Fall 2014 Assignment 8 – Opioids

... Norepinephrine ...
iCup 10 Panel Drug Screening Kit Insert
iCup 10 Panel Drug Screening Kit Insert

... Oxycodone is a semi-synthetic opioid with a structural similarity to codeine. The drug is manufactured by modifying thebaine, an alkaloid found in the opium poppy. Oxycodone, like all opiate agonists, provides pain relief by acting on opioid receptors in the spinal cord, brain, and possibly directly ...
Drug Induced Hyponatraemia - Christchurch Drug Information Service
Drug Induced Hyponatraemia - Christchurch Drug Information Service

... sodium concentrations. However, there are also several medical causes of hyponatraemia and it is important to note that in some patients, multiple factors may contribute to a low serum sodium concentration. Hyponatraemia is defined as a serum sodium concentration <136mmol/L, although symptoms rarely ...
Global Reach of DirecttoConsumer Advertising Using Social Media
Global Reach of DirecttoConsumer Advertising Using Social Media

... Importantly, DTCA is generally banned in all developed countries, with the exception of the United States and New Zealand [5,6]. In the US, the Food and Drug Administration (FDA) has made efforts to provide industry guidance regarding off­label promotion over the Internet, but has yet to issue expli ...
DEVELOPMENT AND VALIDATION OF A RP-HPLC-PDA METHOD FOR THE ANALYSIS... LORNOXICAM IN BULK, TABLETS AND POWDER FOR INJECTION
DEVELOPMENT AND VALIDATION OF A RP-HPLC-PDA METHOD FOR THE ANALYSIS... LORNOXICAM IN BULK, TABLETS AND POWDER FOR INJECTION

... To ensure the validity of the analytical procedure, a system suitability test was established. System suitability parameters for the developed HPLC method were determined by injecting six replicates of the standard solution (30μg/mL). Parameters such as a number of theoretical plates (N), tailing fa ...
Chapter 9
Chapter 9

... - the poppy only as 10 days to manufacture opium Morphine - Frederich Serturner, a German chemist synthesized morphine from opium in 1803 - he called it ‘morphium,’ named for Morpheus, the Greek god of dreams ...
scheme of examination - Guru Gobind Singh Indraprastha University
scheme of examination - Guru Gobind Singh Indraprastha University

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pharmacology and physiology

... This module focuses on developing professional skills to enhance your employability and help you advance in your future career. Topics include good laboratory practice, health and safety regulations, and communication and team-working skills. You also learn how to obtain internships and work placeme ...
MDMA produces stimulant-like conditioned locomotor activity* I
MDMA produces stimulant-like conditioned locomotor activity* I

... Abstract. Daily administration of a drug in a distinctive environment establishes contingencies that support Pavlovian conditioning. Environmental cues that are paired with the drug injection and that predict the onset of drug action can become conditioned stimuli. Ultimately, the conditioned stimul ...
SYALLABUS   OF  B. PHARM. (REGULAR) 4 YEAR PROGRAM
SYALLABUS OF B. PHARM. (REGULAR) 4 YEAR PROGRAM

... ability. Possibility, motivational & scope for self learning Pharmaceutical science helps identify preferred of optimal methods to deliver or dose a drug and reliably ensure therapeutic benefit with minimal side effects at the physiological site of action or disease. The field requires high level sc ...
rav - PHSI
rav - PHSI

... concentration – eventually increase cytosolic calcium.  It restores the vagal tone and abolishes the sympathetic over activity. ...
rav
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... concentration – eventually increase cytosolic calcium.  It restores the vagal tone and abolishes the sympathetic over activity. ...
21. gastroretentiona means to address local
21. gastroretentiona means to address local

... phase, whereas gastric mucus discharge occurs ultrasonography, radiotelemetry and magnetic during the latter part of phase II and throughout marker monitoring in order to study the phase III. Phase III (burst phase): It is parameters affecting the process of gastric characterized by intense distal a ...
Optimal Futures for Risk Evaluation and Mitigation Strategies (REMS)
Optimal Futures for Risk Evaluation and Mitigation Strategies (REMS)

... with rare disorders where treatment options are limited is critical to research and the development of treatment options. This approach avoids increased costs and the need for additional resources to conduct populations-relevant post-marketing studies. ...
Year 2 Drug Table – ST
Year 2 Drug Table – ST

... Patients with high inhibitors. ↓cholesterol ↓Total cholesterol, blood Oral production in the liver. ↑ LDL cholesterol, pressure, diabetes or receptors on hepatocytes → LDL, TGs. ↑HDL MI. ↓ LDL in blood. Ligand for PPAR-α -> ↓10% LDL ↑10% First Line for high TG ↑lipoprotein lipase activity HDL ↓30%TG ...
WHO Drug Information - World Health Organization
WHO Drug Information - World Health Organization

... International Nonproprietary Names INN identifiers for biological products The International Nonproprietary Names (INN) Programme was created by WHO in the 1950s with the intention of providing convenient common names for pharmaceutical substances. At the time of its origin, as well as during its la ...
Prediction of pharmacokinetic properties using experimental
Prediction of pharmacokinetic properties using experimental

... progress in linking ‘in silico’ and higher throughput physicochemical methods with in vitro approaches, progress is being made in predicting PK properties [5]. Such high(er)throughput screening (HTS) efforts require rapid methods and the use of minimum amounts of compounds, so that new molecules can ...
orciprenaline condensed - EBL
orciprenaline condensed - EBL

... •Salbutamol was the first selective Β2-receptor agonist to be marketed — in 1968. It was first sold by Allen & Hanburys under the brand name Ventolin. •Salbutamol is specifically indicated by Acute asthma. •The most common side effects are of fine tremor, nervousness , headache, muscle cramps, dry m ...
20150108- biOasis Q1 - IR Presentation.pptx
20150108- biOasis Q1 - IR Presentation.pptx

... risks, uncertainties and other factors that may cause our actual results, events or developments, or industry results, to be materially different from any future results, events or developments express or implied by such forward-looking statements or information. Such factors include, among others, ...
DSG - TMA
DSG - TMA

...  FDA’s reaction to non-compliance  Form 483  FDA form, used to report inspectoral observations  Usually combined with timelines to fix the problems  Addressed to Top-Management  Usually results in another inspection  Warning Letter  Published letter by the FDA  Reports that a company has no ...
Herbal drugs and drug interactions
Herbal drugs and drug interactions

... There are some reports implying that garlic oil may selectively inhibit CYP2E1, decreasing chloroxazone metabolism; however, this was not supported by further studies (13). In a recent study, it was demonstrated that in women with advanced breast cancer, coadministration of garlic supplement reduced ...
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Pharmaceutical industry



The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.
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