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Vernacular Name
Vernacular Name

... Uses: Aloe is used as irritant purgative. Its activity is increased when it is administered with small amounts of alkaline salts or soaps. Aloe gel is viscous viscid juice. It is a mucilaginous and colorless, widely used in the cosmetic industry as a protective in the treatment of sunburn. It is on ...
Development of Discriminative Dissolution Media for Marketed
Development of Discriminative Dissolution Media for Marketed

... drug product, the dissolution of the drug under physiological conditions, and the permeability across the gastrointestinal tract determine drug absorption. Based on this, in vitro dissolution may be vital in assessing in vivo performance. Dissolution testing serves as a tool to distinguish between a ...
antihypertensive drugs
antihypertensive drugs

... 1. Subcategories (drug classes) and the specific mechanisms 2. Major pharmacokinetic characteristics of each drug class 3. Primary adverse effects of each drug class 4. Unique characteristics of individual agents 5. Similarities and differences in the hemodynamic effects of the drug classes 6. Diffe ...
STABILITY INDICATING HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF  DROTAVERINE AND ACECLOFENAC  Research Article
STABILITY INDICATING HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF  DROTAVERINE AND ACECLOFENAC  Research Article

... spectrum  of  the  drugs  subjected  to  different  forced  conditions;  Changes  in  the  spectra  were  observed  for  all  degradants  of  DRO  except  acid  hydrolysis  and  dry  heat  (Fig  –to  ‐)  while  aceclofenac  showed  spectral  changes  only  on  acid,  base  and  neutral  hydrolysis  ...
Toxicology and safety pharmacology and metabolic studies
Toxicology and safety pharmacology and metabolic studies

... Safety evaluation: requirements for first dose to humans in Phase I • Genetic toxicology - damage to DNA and chromosomes • Secondary/Safety Pharmacology - functional changes at multiples of therapeutic dose; potential off-target activity • General toxicology - target organ toxicity • Reproductive t ...
187 Formulation and Evaluation of Rofecoxib Tablets
187 Formulation and Evaluation of Rofecoxib Tablets

... drugs in the gastro-intestinal tract is dissolution rate limited. Several techniques have been successfully adopted to improve the dissolution rate of these drugs including solid dispersions with various carriers (1), solvent depositions (2), co-grinding with certain carriers (3) and cyclodextrins i ...
QUANTIFICATION OF HEALTH COMMODITIES: ARV COMPANION GUIDE Forecasting ARV Drugs Using the Morbidity
QUANTIFICATION OF HEALTH COMMODITIES: ARV COMPANION GUIDE Forecasting ARV Drugs Using the Morbidity

... regimens consist of three drugs. The initial use of those regimens is influenced by patients’ previous ARV drug history, other co-existing infections or conditions, provider prescribing patterns, drug supply, and other factors. The drugs within a regimen must be adjusted over time to capture the cha ...
jwh-018 - Ministry of Health
jwh-018 - Ministry of Health

... incorporated into herbal smoking blends purporting to provide a legal alternative to cannabis. 8. The Ministry of Health has not been able to provide the Committee with a thorough review of all legally available cannabinomimetic substances. Additionally, for the majority of these substances there is ...
HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHIC METHOD FOR THE SIMULTANEOUS
HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHIC METHOD FOR THE SIMULTANEOUS

... used an antispasmodic[1]. Mefenamic acid is 2-[(2, 3dimethylphenyl) amino] benzoic acid. It has analgesic, antiinflammatory and anti-pyretic properties. It works by blocking the action of a substance in the body called cyclooxygenase which is responsible for production of prostaglandins[2-3]. The li ...
Antiarrhythmic drugs
Antiarrhythmic drugs

... (PVC) following MI, flecainide increased mortality compared to placebo.  CNS effect comman- diziness, visual disturbance, GIT upset ...
Urine Drug Testing Clinical Practice
Urine Drug Testing Clinical Practice

... 50 ng/mL, 49 ng/mL would be reported as negative, while 51 ng/mL would be reported as positive, although these results are, for clinical purposes, identical). Immunoassays are also subject to crossreactivity;14 ie, substances with similar, and sometimes dissimilar, chemical compositions may cause a ...
Isolated systolIc hypertensIon - API
Isolated systolIc hypertensIon - API

... Valsartan in Isolated systolic hypertension (VALISH)15 This study showed a significant effect on ISH. Smaller studies on ISH ACE inhibitors like lisinopril, Enalpril, Periondopril are also suitable for blood pressure control in ISH patients and favourably influence cardiovascular risk factors. In co ...
Legal opium produetion in Afghanistan
Legal opium produetion in Afghanistan

... not have access to effective pain relief, and has encouraged governments to take steps to increase the medical use of opiates in order to meet their real needs for the tre atment of pain. Why do people in developing countries not have access to effective pain relief treatment? Is it because of an un ...
A Systematic Review and Meta-Analysis of the Efficacy of Piracetam
A Systematic Review and Meta-Analysis of the Efficacy of Piracetam

... E-Mail [email protected] ...
VICH GL36(R): Studies to evaluate the safety of residues of
VICH GL36(R): Studies to evaluate the safety of residues of

... Therefore, it may be considered as an option to establish an ADI. The isolates should be obtained from multiple healthy individuals, and include a minimum of 10 isolates from each of the genera listed in Section 2.1. Each MIC test of a pure culture of a relevant isolate provides data for a single st ...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF DONEPEZIL HYDROCHLORIDE  TABLETS BY RP­HPLC  Research Article  T. SENTHIL KUMAR
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF DONEPEZIL HYDROCHLORIDE  TABLETS BY RP­HPLC  Research Article  T. SENTHIL KUMAR

... A simple, rapid and precise RP‐HPLC method has been developed for the determination of donepezil hydrochloride in bulk and tablets. Separation  was achieved with a keystone phenyl RP 250 × 4.6 mm i.d., 5 µM particle size analytical column using mixture of methanol, 0.02M phosphate Buffer  (pH 7.5 ±  ...
Attention-Deficit Hyperactivity Disorder (ADHD) Drug
Attention-Deficit Hyperactivity Disorder (ADHD) Drug

... if diversion and/or misuse, comorbid tics or anxiety, or non-response / contraindication to stimulants are concerns. Core symptoms are reduced by at least 25% in 60–70% of individuals after 6–12 weeks of treatment.6 However, atomoxetine is associated with a smaller effect size (0.62) than stimulants ...
full prescribing information
full prescribing information

... benzodiazepines. The more severe withdrawal symptoms have usually been limited to patients who received excessive doses over an extended period of time, followed by an abrupt discontinuation. Generally milder withdrawal symptoms (e.g., dysphoria, anxiety, and insomnia) have been reported following a ...
自動進口許可証 (新舊機電產品)
自動進口許可証 (新舊機電產品)

... be enforced with reference to the provisions of the regulations of the regulatory and issuing entities of the Mainland. The national administrative documents are used for customs clearance, and is a measure by the Mainland for the administration of imports and exports trade. The customs clearance fo ...
The Quick Response Team provides this Directory for information
The Quick Response Team provides this Directory for information

... MYTH 2: Addiction is a disease; there’s nothing you can do about it. Most experts agree that addiction is a brain disease and that it is a chronic disease. However don’t call the addict a “helpless victim”. Addiction is a disease but not an excuse and just like any other person with a chronic diseas ...
S A M P L E   C H...
S A M P L E C H...

... angina, heart failure or a history of MI. Beta-blockers are also useful in patients who have migraine headaches, tachycardia or essential tremor. However, beta-blockers are not as effective as angiotensin II receptor blockers (ARBs), calcium channel blockers (CCBs) or diuretics as initial therapy fo ...
IN VIVO TABLETS BY HYDROXY PROPYL BETA CYCLODEXTRIN COMPLEXATION Research Article
IN VIVO TABLETS BY HYDROXY PROPYL BETA CYCLODEXTRIN COMPLEXATION Research Article

... administered and some are retained in the mouth where the active substance is liberated [1]. The advantages of this dosage form are manifold: tablets are cost effective to manufacture, convenient to dispense and store, and easy for the patient to administer and they provide a versatile means of deli ...
FORMULATION OF RAPID MOUTH DISSOLVING TABLETS OF CETIRIZINE di HCL USING  SUBLIMATION METHOD  Research Article   
FORMULATION OF RAPID MOUTH DISSOLVING TABLETS OF CETIRIZINE di HCL USING  SUBLIMATION METHOD  Research Article   

... Mouth dissolving Drug Delivery System gain their attention in order  to  improve  efficacy  and  patient  compliance  in  one  of  the  most  convenient  dosage  form  i.e.  Tablet  due  to  difficulty  in    swallowing  them1 and this lack of convenience results in high incidence of non‐ compliance ...
alcohol, drugs and substance misuse policy
alcohol, drugs and substance misuse policy

... 8.3.4 Employees are required to attend occupational health appointments in line with this procedure. The line manager will make a referral to occupational health giving full background to the case. 8.3.5 If the Occupational Health Service does not confirm the existence of an alcohol, drug and/or sub ...
ROBERT E. GOLDSTEIN and STEPHEN E. EPSTEIN 1973;48:917-920 doi: 10.1161/01.CIR.48.5.917
ROBERT E. GOLDSTEIN and STEPHEN E. EPSTEIN 1973;48:917-920 doi: 10.1161/01.CIR.48.5.917

... drug. For these reasons, broadly applicable conclusions cannot be made with certainty about the relative merits of two nitrate preparations based upon patient performance after a single arbitrarily ebosen dose of each drug. A number of different nitrate esters have been offered as sublingual substit ...
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Pharmaceutical industry



The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.
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