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What is the other 85% of V1 doing?
What is the other 85% of V1 doing?

... approach tells you anything useful depends entirely on how you reduce. Some modes of interaction may be crucial to the operation of the system, and so cutting them out—either in theories or experiments—may give a misleading picture of how the system actually works. Obviously, if one knew in advance ...
Expectation of reward modulates cognitive signals in the basal ganglia
Expectation of reward modulates cognitive signals in the basal ganglia

... to-be-attended location or object, and reward was given consistently. Here the required cognitive processing was identical for different target locations, but the reward outcome was different. The basal ganglia may direct attention to items associated with reward, whereas the cerebral cortex, especi ...
Cognitive-Neuroscience-3rd-Edition-Gazzaniga-Test
Cognitive-Neuroscience-3rd-Edition-Gazzaniga-Test

... 28. In myelinated axons, action potentials are generated a. at the nodes of Ranvier only. b. along the entire length of the axons. c. underneath the myelinated portions of the axons only. d. only at the axon hillocks and axon terminals. ANS: A ...
Drug-drug interactions in inpatient and outpatient settings in Iran: a
Drug-drug interactions in inpatient and outpatient settings in Iran: a

... and activate internal signal transduction pathways that cause cellular responses. They are also called seventransmembrane receptors because they have seven subunits that pass through the cell membrane [12]. The ligands that bind and activate these receptors include, hormones, neurotransmitters, and ...
Local Gene Expression in Axons and Nerve Endings: The Glia
Local Gene Expression in Axons and Nerve Endings: The Glia

... consequence on the trophic support of the axonal periphery. How could a cell body metabolically sustain an axon comprising more than 100-fold its mass? How could a perikaryon synthesize all the axonal, presynaptic, and dendritic proteins in addition to its own? How could it deliver them to the right ...
Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia
Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia

... cloned from mouse and initially named Necab. It encodes a 389aa (NECAB2) (24). NECAB2 was identified as a downstream target of Pax6 in mouse retina, which is involved in retinal development (24, 25), as well as being a binding partner for the adenosine A2A receptor (22). Furthermore, an interaction ...
Corticothalamic feedback and sensory processing
Corticothalamic feedback and sensory processing

... fields [36,37], identifying suppressive regions of VB receptive fields has been more difficult. Nevertheless, studies have shown that the spatial profile of VB receptive fields can expand (and sometimes contract) following inactivation of primary somatosensory cortex (Figure 3c [23,24]). Thus, at l ...
D5 (Not D1) Dopamine Receptors Potentiate Burst
D5 (Not D1) Dopamine Receptors Potentiate Burst

... also be induced in approximately one neuron in two by continually injecting a small hyperpolarizing current (Fig. 2 A). Burstcompetent neurons give specific responses, called plateau potentials, to short current pulses given at hyperpolarized levels (Nakanishi et al., 1987; Beurrier et al., 1999; Be ...
What does the eye tell the brain? Development of a system for the large-scale recording of retinal output activity
What does the eye tell the brain? Development of a system for the large-scale recording of retinal output activity

... has approximately 100 million light-sensitive pixels (the photoreceptors, both rods and cones) that cover an area of about 10 cm , and approximately one million output neurons (the retinal ganglion cells, RGCs) that generate the spike trains. The output fibers (axons) of the ganglion cells form the ...
Robo1 Regulates the Migration and Laminar Distribution of Upper
Robo1 Regulates the Migration and Laminar Distribution of Upper

... elusive (Magdaleno et al. 2002; Yoshida et al. 2006). Alternative signaling pathways may contribute to this process (Moers et al. 2008), but the positioning defects appear only in a limited number of neurons. This prompted us to investigate whether additional mechanisms may contribute to the correct ...
Stereological estimation of dendritic coverage in the capybara SCG
Stereological estimation of dendritic coverage in the capybara SCG

... methodology. Based on an allometric analysis, which took into account the SCG volume, we have previously predicted some 34.1 billion axo-dendritic synapses in capybara SCG against the actual finding of 56.4 billion synapses [11]. Consequently, the SCG volume alone is not the principal determinant of ...
Document
Document

... Ascending tracts of posterior funiculus Sensory ganglionic cells are the primary neurons. Their dendrites innervate receptors of many kinds of discriminative sensations (limb position and movement, pressure, vibration, precise touch) and convey impulses running in spinal nerve towards the spinal ga ...
Physiological and Morphological Analysis of Synaptic Transmission
Physiological and Morphological Analysis of Synaptic Transmission

... transmission coefficient was similar for either set of motor neurons, DI-1 and DE-3 or VI-2 and VE-4. The mean value for combined data from all measurements was 0.51 (SD = 0.10, N = 10). Given the anatomical relationships between inhibitors and excitors, described below, it is highly likely that the ...
Questions and Answers From Episode 27
Questions and Answers From Episode 27

... nasal mucosa that are bathed in nasal mucus. The mucus protects the receptors and also contains growth factors that help to maintain the function of the receptors. In order for an odorant to be smelled, the receptor must be stimulated so that it can send a message to an area of the brain (cortex) th ...
Linköping University Post Print the developmental age of the cells
Linköping University Post Print the developmental age of the cells

... (Glut3) expression is reduced with increasing neuronal age (Fattoretti et al. 2001). Patel and Brewer (2003) found that the rate of glucose uptake in cultured embryonic neurons was threefold greater than in neurons taken from middle-aged and old donor rats. Thus, it is possible that the age of neuro ...
The Autonomic Nervous System and Visceral Sensory Neurons 15
The Autonomic Nervous System and Visceral Sensory Neurons 15

... side). All of them help us respond to dangerous situations: The increased heart rate delivers more blood and oxygen to the skeletal muscles used for fighting or running; widened pupils let in more light for clearer vision; and cold skin indicates that blood is being diverted from the skin to more vi ...
Glial Signaling Take Home Messages
Glial Signaling Take Home Messages

... iii. Astrocytes and D-serine necessary for neuronal LTP c. D-serine binds the Gly site on neuronal NMDA receptors → ↑ LTP 2. Astrocyte signaling → ↑ LTP is limited to local astrocyte networks 3. Astrocytes are required for some types of synaptic plasticity (like LTP) 4. Human Astrocytes (hAstrocyt ...
Morphological and Quantitative Study of Neurons in the Gracile
Morphological and Quantitative Study of Neurons in the Gracile

... reach the thalamus and ultimately the cortex after a relay at a bulbar level; the Gr and Cu. These nuclei were particularly attractive targets for studying early stages of sensory processing in the somatosensory pathways [16]. In all species studied, these nuclei receive somatotopically arranged pri ...
Phase IIB / PHGY 825 Organization of the Brain Stem Organization
Phase IIB / PHGY 825 Organization of the Brain Stem Organization

... The coordination of orofacial motor responses involves the lateral medullary and pontine reticular formation: • Chewing is coordinated by neurons near the trigeminal motor nucleus. • Lip movements are coordinated by neurons near the facial motor nucleus. • Movements of the tongue are coordinated by ...
A Critical Review of the Role of the Proposed VMpo Nucleus in Pain
A Critical Review of the Role of the Proposed VMpo Nucleus in Pain

... nervous system nuclei is usually based on cytoarchitecture, rather than on fiber architecture, although the patterns of connections of a nucleus are obviously important. A major problem is that it is unclear to what extent the calbindin-positive axons in this case terminate in the proposed nucleus a ...
Nervous Tissue
Nervous Tissue

... Dr. Michael P. Gillespie ...
Transformation from temporal to rate coding in a somatosensory
Transformation from temporal to rate coding in a somatosensory

... left insets). The averaged latency and spike-count representations of the whisker frequency (Fig. 2, right insets) depict typical representations of single local populations in each of the stations. These pathway-speci®c representations occurred for all well localized recording sites, except for 1 o ...
MacDermott Lab
MacDermott Lab

... . Look at the astrocyte dishes under the microscope to pick out the healthiest ones . Remove all of the IMDM from the dishes and replace with MEM for NEURONS or with Neurobasal + B-27 . Thaw a 200 l aliquot of 2.5% trypsin and reserve . Add 2 ml of S-MEM into a 35 mm dish and place in the incubator ...
Vertical Organization of r=Aminobutyric Acid
Vertical Organization of r=Aminobutyric Acid

... all cells within a column share similar receptive field properties. Convergence of vertically organized inputs appears responsible, at least in part, for the additional functional properties that distinguish superficial and deep cortical cells from those lying at the heart of the thalamic terminal l ...
Basal Ganglia: Internal Organization
Basal Ganglia: Internal Organization

... are subdivided into two major subpopulations on the basis of their projection region, pattern of axonal collateralization, and neurochemical content. One subpopulation gives rise to the direct pathway, they preferentially project to the output nuclei of the basal ganglia (but also send a collateral ...
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Axon guidance

Axon guidance (also called axon pathfinding) is a subfield of neural development concerning the process by which neurons send out axons to reach the correct targets. Axons often follow very precise paths in the nervous system, and how they manage to find their way so accurately is being researched.
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