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1-coronary valve
1-coronary valve

... node and the atrioventricular node . The cardiac muscle is composed of myocytes which initiate contraction without help of external nerves. Under normal circumstances, each cycle takes approximately one second. ...
Acute Heart Failure and Atrial Fibrillation
Acute Heart Failure and Atrial Fibrillation

... approach to patients who can easily be rate controlled, are very unlikely to maintain sinus rhythm in the long term, and who are not bothered by symptoms such as palpitations that are attributable to AF. Nevertheless, certain circumstances may warrant attempts at rhythm control depending on a patien ...
click here  - Cardiomyopathy UK
click here - Cardiomyopathy UK

... European Society of Cardiology practice guidelines: Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death (2015), Diagnosis and management of hypertrophic cardiomyopathy (2014), Atrial Fibrillation (Management of) 2010 and Focused Update (2012). NICE pathways: heart defects (structural) ...
Treatment of Heart Failure - familypracticeresidency.org
Treatment of Heart Failure - familypracticeresidency.org

... symptoms have QRS>120 msec Mechanical consequences of dysynchrony ...
ANESTHETIC MANAGEMENT OF DILATED CARDIOMYOPATHY
ANESTHETIC MANAGEMENT OF DILATED CARDIOMYOPATHY

... myocardial disease of unknown cause characterized by left ventricular or biventricular dilatation and impaired myocardial contractility. Most patient are first seen between the ages of 20 and 50 Years, but it may affect children and the elderly. The most common initial manifestation as seen in this ...
Heart and work Cardiac reserve - Energy Energy Force and pressure
Heart and work Cardiac reserve - Energy Energy Force and pressure

... (PLV) is required (Laplace’s law). Forward HF with diminished contractility develops. An analogous situation exists regarding the right ventricle in pulmonary hypertension. Compensatory hypertrophy will also develop when there is an increased pressure load, but it will be “concentric” , because in t ...
A. Septal B. Anterior C. Free Wall
A. Septal B. Anterior C. Free Wall

... The RVOT is used as an alternative pacing site, but its superiority to the RV-apex remains to be established. The aim of the present study is to characterize the RVOT in terms of fluoroscopic and electrocardiographic parameters. ...
Electrocardiogram (EKG) - Imperial Cardiac Center
Electrocardiogram (EKG) - Imperial Cardiac Center

... To understand this test, it helps to understand how the heart works. With each heartbeat, an electrical signal spreads from the top of the heart to the bottom. As it travels, the signal causes the heart to contract and pump blood. The process repeats with each new heartbeat. The heart's electrical s ...
Torsades de Pointes during Treatment of Tachycardia
Torsades de Pointes during Treatment of Tachycardia

HeartMate II left ventricular assist device
HeartMate II left ventricular assist device

... aggravating the scarcity of donor organs. Since the landmark trial Rematch (randomized evaluation of mechanical assistance for the treatment of congestive heart failure) [3] showed that implantation of a LVAD improves survival superior to any medical treatment and with the emergence of newly designe ...
Heart rhythm at the time of death documented by an implantable
Heart rhythm at the time of death documented by an implantable

... VF and ultimately into asystole. This course of events was confirmed in ambulatory monitoring studies.9 Recently, the investigators of the Cardiac Arrhythmias and RIsk Stratification after Myocardial infArction (CARISMA) study reported the results of 2 years of continuous arrhythmia monitoring in po ...
Index of T-wave Variation as a Predictor of Sudden Cardiac Death in
Index of T-wave Variation as a Predictor of Sudden Cardiac Death in

... of 176 patients (134 males) with AF aged 35-90 years (68.77±10.22 years) were available for the present study. ECG signals were acquired by using SpiderView records (ELA Medical, Sorin Group, Paris, France) and two or three orthogonal leads (X, Y, Z) sampled at 200 Hz were recorded for each subject. ...
Aldosterone, ion channels, and sudden death: another - AJP
Aldosterone, ion channels, and sudden death: another - AJP

... action potential duration. This effect appeared dependent on the mineralocorticoid receptor (MR) because it was blocked with the MR antagonist spironolactone but not with the glucocorticoid receptor antagonist RU-38486. Confirming previous results from Bénitah and colleagues, this report also demon ...
Heart
Heart

... standstill or ventricular fibrillation may occur when serum levels reach 10 to 12 mEq/L. ...
Cardiac Tamponade: A Classic Presentation
Cardiac Tamponade: A Classic Presentation

... The radiograph (A) reveals a massively enlarged cardiac silhouette. It is important to use the term "cardiac silhouette" rather than "cardiomegaly" in this setting because the first term is broader and encompasses pericardial effusion. The "water bottle" appearance of the cardiac silhouette here ind ...
CV-1
CV-1

... standstill or ventricular fibrillation may occur when serum levels reach 10 to 12 mEq/L. ...
Arrhythmias – Clinical Update
Arrhythmias – Clinical Update

... do not have a normal heart are a worry, and Dr Lyne spoke about arrhythmia in the context of heart disease. He cited the case of a 65-year-old patient with a ventricular tachycardia associated with a previous ...
Implantable Cardioverter Defibrillators (ICDs)
Implantable Cardioverter Defibrillators (ICDs)

... For Cardiac Resynchronization Therapy (Biventricular Pacemakers)/Combination Resynchronization-Defibrillation Devices for Heart Failure, alone or in combination with an AICD(CRT/AICD) may be covered when all of the following are met: Please check the indication that applies to this request for prior ...
The importance of a metabolic approach to anti
The importance of a metabolic approach to anti

... substrates, trimetazidine reduces ischemia and brings about an improvement in symptoms. Importantly, a significant literature now exists supporting a direct anti-ischemic effect of trimetazidine on myocardial cells that is recognized to be a cardioprotective action ...
Which surgical patients benefit from perioperative beta
Which surgical patients benefit from perioperative beta

presentation
presentation

... Benefit: This specific feature is what this system monopolizes on. It’s ability to use information that is regarded as “insignificant or unusable” by the traditional ECG systems, is what sets it apart from the rest ...
-full page
-full page

... • an angiotensin-receptor/neprilysin inhibitor (ARNI), showed as sharp an edge against the ACE-inhibitor comparator for the CV death/heart-failure hospitalization primary end point regardless of baseline LV ejection fraction or whether the target dosage was achieved. ...
Cardiovascular Physiology - San Diego Miramar College
Cardiovascular Physiology - San Diego Miramar College

... Cardiac Output can more than double during moderate exercise for the average adult Elite athletes can have Cardiac Outputs in excess of 25 l/min! 180 bpm x 160 ml/beat = 28.8 l/min ...
Arrhythmia - Ali Alalawi
Arrhythmia - Ali Alalawi

... By Ali alalawi ...
Heart
Heart

... P wave: atrial depolarization; <100ms PQ (PR) segment: atrial plateau phase PQ (PR) interval: Atrial depolarization and conduction through AV node; 120-200 ms QRS duration:80-120 ms; Ventricular depolarization and atrial repolarization QT interval: Ventricular depolarization plus ventricular repolar ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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