• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Second-Degree Heart Block (Second-Degree Atrioventricular Block
Second-Degree Heart Block (Second-Degree Atrioventricular Block

... • The normal heart rate for dogs varies based on the size of the dog; however, the general range is 60–180 beats per minute (with smaller dogs having faster normal heart rates) • The general range for normal heart rates in cats is 120—240 beats per minute • An electrocardiogram (ECG) is a recording ...
Hormonal Profile in Patients With Dilated Cardiomyopathy
Hormonal Profile in Patients With Dilated Cardiomyopathy

... poor. The pathophysiology of HF is closely associated with neuroendocrine changes. The activation of neuroendocrine systems contributes to the progression of HF (3-5). Many neuroendocrine factors are changed in congestive HF (CHF). The neuroendocrine changes not only are a marker of the severity of ...
Simple method of assessment of right ventricular systolic function by
Simple method of assessment of right ventricular systolic function by

... Any information contained in this pdf file is automatically generated from digital material submitted to EPOS by third parties in the form of scientific presentations. References to any names, marks, products, or services of third parties or hypertext links to thirdparty sites or information are pro ...
Cardiac System - My Illinois State
Cardiac System - My Illinois State

... - Mode of response to sensed electrical impulses (inhibited or triggered) - Rate modulation - Multi site pacing ...
heart failure - Our Public Health SA
heart failure - Our Public Health SA

... Treatment strategies include a combination of medication like: ...
Pediatric Cardiac Emergencies
Pediatric Cardiac Emergencies

...  congenital long QT associated with hypertrophic cardiomyopathy  long QT defined as corrected QT longer than 0.44 s  T wave alternans sometimes present  can have normal ECG in the department  two clinical syndromes not associated with structural heart disease: Romano-Ward and Jervell-Lange-Niel ...
Statistical Issues in Interpreting Clinical Trials
Statistical Issues in Interpreting Clinical Trials

... PRAISE-II directly opposed the exciting results of PRAISE-I’s subgroup analysis ...
Jake - Wendy Blount, DVM
Jake - Wendy Blount, DVM

... • Treatment was declined, and Jake was euthanatized 1 week later • Most dogs with DCM are gone within 3 months of becoming symptomatic, if treated with furosemide & ACE. • Survival is likely much shorter – days to weeks – if untreated. • Adding Pimobendan increases mean survival to 130 days. • Media ...
Heart - El Camino College
Heart - El Camino College

... 3. ______cardium – thin endothelium that lines heart chambers a. _____________ is an infection of the endocardium, usually bacterial; can cause deterioration of heart valves B. Cardiac muscle cells rely mostly on ___________ respiration and are connected end to end by _______________ discs composed ...
Understanding Congestive Heart Failure
Understanding Congestive Heart Failure

... maintain blood flow in one direction. The arteries and veins are the roadways ...
Certificate in Electrocardiography
Certificate in Electrocardiography

... d) Features of the normal 12-lead resting electrocardiogram and the recognition of some common abnormalities. The examination paper is in two parts Paper One – Anatomy and Physiology. Paper Two – Electrocardiographic Instrumentation, Technique and ECG Interpretation. Paper Two contains an Essential ...
Post-test to accompany acute coronary syndrome
Post-test to accompany acute coronary syndrome

... 1. What is the purpose of aspirin given early on in an acute coronary event? a) To decrease the chest pain b) To protect the lining of the stomach c) To help with headaches d) To decrease platelet aggregation 2. What does the ventricular tachycardia protocol require as a first action? a) Check for p ...
Phases of the Cardiac Cycle Atrial systole begins: Atrial
Phases of the Cardiac Cycle Atrial systole begins: Atrial

... o Central venous pressure Starlings Law of the heart Increasing venous return and ventricular preload leads to an increased stroke volume Factors Effecting Preload:  Atrial Contraction  Venous Pressure  Ventricular Compliance  Heart Rate Side Note: Decreased Compliance leads to decreased stretc ...
View Revision Note
View Revision Note

...  Atrial systole runs until the atrioventricular valves close  Ventricular systole runs from when the atrioventricular valves close to when the semilunar valves close  Diastole runs from when the semilunar valves close to the beginning of atrial systole Heart muscle is very different from other mu ...
CONTINUOUS INTRAOPERATIVE TEE MONITORING FOR A CHILD WITH FONTAN PATHWAY I
CONTINUOUS INTRAOPERATIVE TEE MONITORING FOR A CHILD WITH FONTAN PATHWAY I

... Improved treatment of congenital heart disease has given patients opportunity to present as adolescents and adults for noncardiac surgical procedures. Idiopathic scoliosis occurs in 2-4% of the general population1; though four times increased incidence in patients with cyanotic heart conditions2. Th ...
Document
Document

... How symptomatic is patient • Signs of poor cardiac output – Heart rate • Too fast – depends on rhythm • Too slow – depends on patient ...
Anesthesia for Organ Transplantation
Anesthesia for Organ Transplantation

... The ECG may have a double P wave, reflecting atrial activity in the native atrial cuff and the transplanted atrium ...
Mar 2016 Faulty heart valves may eventually need surgery
Mar 2016 Faulty heart valves may eventually need surgery

... muscle disease which may lead to enlargement of the heart chambers and subsequent valve failure. Cardiac muscle disease results in weakened heart muscles and often heart enlargement. Broadly, the causes of this are also either congenital or acquired. Some people with heart valve disease have no symp ...
SPC - Servier
SPC - Servier

... 4.8). Atrial fibrillation has been more common in patients using concomitantly amiodarone or potent class I anti-arrhythmics. It is recommended to regularly clinically monitor ivabradine treated patients for the occurrence of atrial fibrillation (sustained or paroxysmal), which should also include E ...
Full Text
Full Text

... decompensated HF based on ADHERE (Acute Decompensated Heart Failure National Registry), which had 108,927 patients, there was a 10% lower risk-adjusted mortality (95% confidence interval: 0.88 to 0.93, p ⬍ 0.0001) for every 5-unit increase in BMI (15). In chronic HF based on the CHARM (Candesartan i ...
1- Dilated cardiomyopathy
1- Dilated cardiomyopathy

... myocardial dysfunction - usually present with heart failure and arrhythmias - there are 3 main types of cardiomyopathy: 1- dilated cardiomyopathy 2- hypertrophic 3- restrictive 1- Dilated cardiomyopathy: (DCM) - is characterized by: 1- four-chamber dilation 2- myocardial hypertrophy 3- impairment of ...
Pediatric Cardiac Emergencies
Pediatric Cardiac Emergencies

... – T wave alternans sometimes present – can have normal ECG in the department – two clinical syndromes not associated with structural heart disease: Romano-Ward and Jervell-LangeNielsen ...
Sport and Arrhythmogenic Right Ventricular Cardiomyopathy
Sport and Arrhythmogenic Right Ventricular Cardiomyopathy

... exercise participation is so common and at a level that appears to be higher than in the general population. The link between endurance sport and ARVC may be more than coincidental, as shown in animal studies, in which endurance training accelerates the development of right ventricular dysfunction a ...
6-CARDIAC_OUTPUT
6-CARDIAC_OUTPUT

... Cardiac output is the amount of blood pumped by each ventricle per minute (5L/min). It varies physiologically with age, body mass index, physical activity, sleep, meals, pregnancy, etc.. But there are pathological conditions that lead to a significant increase in CO including hyperthyroidism, anemia ...
altitude - Boston Scientific
altitude - Boston Scientific

... Read the product labeling thoroughly before implanting the pulse generator to avoid damage to the system. Such damage can result in patient injury or death. Program the pulse generator Tachy Mode to Off during implant, explant or postmortem procedures to avoid inadvertent high voltage shocks. Always ...
< 1 ... 506 507 508 509 510 511 512 513 514 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report