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... inherited. There is no treatment or cure for this condition and patients have a higher risk of SADS (Sudden Adult Death Syndome) so nocturnal monitoring with PulseGuard ™ would alert to the onset of SADS and allow for early emergency medical intervention. Congenital Heart Defects – This is where a h ...
Congenital Absence of the Left Pericardium and Complete Heart Block
Congenital Absence of the Left Pericardium and Complete Heart Block

... memay ...
Untypical cause of heart failure – right atrial myxoma
Untypical cause of heart failure – right atrial myxoma

... Copyright by Medycyna Praktyczna, Kraków 2007 Untypical cause of heart failure – right atrial myxoma ...
Module 5a: Documenting Heart Failure
Module 5a: Documenting Heart Failure

... CMS guidelines require acuity and specificity. Incomplete documentation of heart failure has a significant impact on severity of illness, risk of mortality, GLOS, and case mix index. Incomplete documentation affects treatment modalities, core measures, and communication. Incomplete documentation aff ...
Conditions Requiring Antibiotics Before Dental
Conditions Requiring Antibiotics Before Dental

... These recommendations are based upon a variety of in vitro studies, clinical experience, animal model data and an assessment of the common oral flora most likely to cause potential bacteremia. Definitive patient risk/benefit ratios for these prophylactic procedures have not been definitively determi ...
copyright 2002 scientific american, inc.
copyright 2002 scientific american, inc.

Impact of Physical Inactivity on Mortality in Patients With Heart Failure
Impact of Physical Inactivity on Mortality in Patients With Heart Failure

... patients with symptomatic HF. Details of the trial were reported elsewhere.4,5 The study enrolled patients from 10 centers in the Chicago metropolitan area and was approved by the institutional review board of each collaborating institution [NCT00018005]. Briefly, HART enrolled patients with HF with ...
ST120 Unit 2: The Heart
ST120 Unit 2: The Heart

...  Atrial flutter - atrial rate of 250-350 beats per minute; can result in increased ventricular rate and decrease in oxygen  Atrial fibrillation - atrial rate of 350-600 beats per minute; results in increased ventricular rate and decrease in oxygen ...
Tissue inhibitor
Tissue inhibitor

... [17]. Elevated levels of TIMP-1 have been consistently reported in chronic heart failure (CHF) regardless of the underlying cause or the type of left ventricular dysfunction [8,11,15,18,19], and a level N 1200 ng/ml was indicative of heart failure [20]. However, the available information regarding t ...
File
File

... • 5.1 Describe the pathological changes that could be seen in the heart of this patient? (50) • 5.2 List 2 other causes for endocardial vegetation? (20) • 5.3 Name 3 extra cardiac manifestations of rheumatic fever? (30) ...
Heart transplantation
Heart transplantation

... Coronary Heart Disease is leading disease for which people receive premature disability benefits 88% are able to return to work after an MI Jobs may need to be modified, customized ...
Palpitations Pathway - Harrogate and Rural District CCG
Palpitations Pathway - Harrogate and Rural District CCG

... interventions for defined arrhythmias such as AF and define when specialist referral is indicated. ...
Cardiac Resynchronization Therapy
Cardiac Resynchronization Therapy

... Background CRT and MediGuide™ Technology CRT is a well established therapy for patients with advanced Heart Failure (HF). The number of implantations is rapidly increasing worldwide. In the US and Europe together, more than 150.000 CRT devices are implanted each year. In conventional CRT device impl ...
Chapter 3 Activities (part I) - Pearson Schools and FE Colleges
Chapter 3 Activities (part I) - Pearson Schools and FE Colleges

... 1. What happens to heart rate (HR) as exercise intensity increases? 2. What happens to SV from supine to sitting and then to standing? Why? 3. What happens to cardiac output (Q) from supine to sitting and standing? 4. What happens to HR, SV and Q from walking to jogging and running? 5. Why does the ...
When to implant an ICD and which one
When to implant an ICD and which one

... • Multicenter registry study of implanted ICDs in 506 unrelated patients with HCM @ high risk for SCD (family hx of SCD, [septal thickness ≥ 30 mm], NSVT, syncope) • Mean patient age 42 years (SD=17) and 87% had no or only mildly limiting symptoms • Appropriate ICD discharge rates were 11% per year ...
PDF file - Via Medica Journals
PDF file - Via Medica Journals

... coronary artery by-pass grafting) brings most benefit to those patients, in whom left ventricular dysfunction related to coronary artery disease is the effect of chronic heart muscle hibernation [1]. According to Braunwald and Rutherford, heart muscle hibernation is defined by the decrease of contra ...
Heart Failure with Preserved Ejection Fraction
Heart Failure with Preserved Ejection Fraction

... remodelling and, hence, on LV ejection fraction. The heart failure disease trajectory is influenced by numerous patient characteristics that function as ‘disease modifiers’. These modifiers include diabetes, arterial hypertension and female gender, which promote disease progression without eccentric ...
A View of the Cardiovascular Device Industry
A View of the Cardiovascular Device Industry

... CorInnova Inc. is an early stage medical device company with a focus in devicebased therapies for congestive heart failure. Founded in 2004 by Dr. John Criscione, Biomedical Engineering professor at Texas A&M University, CorInnova is developing a cardiac assist device and is currently in the early s ...
Chapter Two Line Title Here and Chapter Title Here and Here
Chapter Two Line Title Here and Chapter Title Here and Here

... 1. The heart is the size of a fist and weighs 250–300 grams. 2. The heart is found in the mediastinum and two-thirds lies left of the midsternal line. 3. The base is directed toward the right shoulder and the apex points toward the left hip. B. Coverings of the Heart (pp. 660–661; Fig. 18.3) 1. The ...
Prognostic significance of QRS duration and morphology
Prognostic significance of QRS duration and morphology

... QRS duration and morphology, evaluated via a standard 12-lead electrocardiogram (ECG), represent an opportunity to derive useful prognostic information regarding the risk of subsequent cardiac events or therapeutic outcomes. Prolonged QRS duration, and the presence of intraventricular conduction abn ...
May 2015 Newsletter
May 2015 Newsletter

... with meals. The most common side effects include slow heart rate and atrial fibrillation. High blood pressure and visual disturbances can also occur. This drug can be harmful to unborn babies and should not be used during pregnancies. The SHIFT trial showed that people taking Ivabradine had a 26 per ...
Nerve activates contraction
Nerve activates contraction

...  Blood vessels within the lungs become swollen and fluid leaks into the lung tissue causing pulmonary edema. If untreated, the person suffocates. ...
Adaptive Cardiac Hypertrophy May Be Reversible
Adaptive Cardiac Hypertrophy May Be Reversible

... 4 Weeks ID: Decreased LVP Partial ID: LVP similar to controls Morphology similar to controls ...
Implantable Cardioverter Defibrillators or Cardiac
Implantable Cardioverter Defibrillators or Cardiac

... Clinical questions are developed by the Division of Evidence Development and Standards at Health Quality Ontario in consultation with experts, end-users, and/or applicants in the topic area. A systematic literature search is then conducted to identify relevant systematic reviews, health technology a ...
The economical challenge in the treatment of chronic heart failure: is
The economical challenge in the treatment of chronic heart failure: is

... were lower (,5 years)16 than the assumption of 6.5 years in the present analysis. However, cost-effectiveness studies should be based on actual ICD longevity. (iii) The present study was based on a constant ICD efficacy during lifetime. Substudies of MADIT II and SCD-HeFT showed an increased mortali ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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