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Acute Hemodynamic Effects of Hexa
Acute Hemodynamic Effects of Hexa

... following termination of injection. The following changes from the basal during the experimental period were considered significant: (a) 20 per cent for mean brachial artery pressure, (b) more than 10 per cent for cardiac index, (c) more than 15 beats per minute for heart rate, (d) 5 mm. Hg for pulm ...
free article - University of Kansas Medical Center
free article - University of Kansas Medical Center

... resulting left ventricular dysfunction remains one of the major causes of chronic heart failure [1]. Experimental and clinical studies have shown that intracoronary injection of mononuclear bone marrow cells (BMC) in patients with acute myocardial infarction may improve left ventricular perfusion an ...
lab - Zoology, UBC
lab - Zoology, UBC

... 1. Attach the thread to the transducer lever with plasticine. Arrange the bath so that the thread is vertical. Do not pull the thread too tight; it should be taut, but should not stretch the heart excessively. Balance the lever with plasticine as demonstrated. Keep the heart moist at all times with ...
PDF - Romanian Journal of Cardiology
PDF - Romanian Journal of Cardiology

... Abstract: Introduction – Since apical rotation is a key determinant of left ventricular (LV) performance we hypothesized that the worse outcome observed in pts with anterior myocardial infarction (MI) may be, at least partly, a consequence of LV apical involvement. Methods – We analyzed retrospectiv ...
Cardiovascular - Aurora Health Care
Cardiovascular - Aurora Health Care

... accomplish in this lifetime and, fortunately, he is going to be able to do that and do it well and feeling well,” Crouch said. “And for us, that is the gratification we get and that’s why we do this.” ...
Diagnosis of arrhythmogenic right ventricular
Diagnosis of arrhythmogenic right ventricular

... Figure 3. Cardiac magnetic resonance images in frames from horizontal long-axis cine sequence treatment option for ARVC, several issues can showing (a) end systole with irregular silhouette of the free right ventricular wall due to microaneurysms render ICDs both less effective and potentially (arrow ...
brief communications
brief communications

... constrictive pericarditis due either to the presence of intrapericardial clotted blood or chronic inflammation has been well described.1-3We describe here an unusual patient who presented with massiveorganized intrapericardial hematoma with the hemodynamic characteristics of chronic constrictive per ...
MYOCARDITIS
MYOCARDITIS

... • 80 patients with clinically suspected myocarditis were screened for CK activity, CK-MB and cTnT • Endomyocardial biopsy specimens were examined histologically and immunohistologically • cTnT was elevated in 28 patients, CK in 4 and CK-MB in 1 • Immunohistologic analysis revealed evidence of myocar ...
ARRHYTHMIAS IN CHILDREN
ARRHYTHMIAS IN CHILDREN

...  In the case of administration through peripherial vein by small diameter, the dose can be slightly increased to 0,15 mg/kg, with possibility to repeat the dose over 10 minutes without to exceed 0,4 mg/kg or 12 mg totally(see emergency treatment).  In the case of failure the propafenone, amiodaron ...
Poor Prognosis of Japanese Patients With Chronic Heart Failure
Poor Prognosis of Japanese Patients With Chronic Heart Failure

... mortality in the CHF patients with preserved LVEF or fewer symptoms (Table 3). However, this significant impact of ischemic etiology was not observed in the Cox regression models using the total study population including CHF patients with severely impaired LVEF or more severe symptoms. Diastolic He ...
Protocol of fMCG
Protocol of fMCG

... A high quality averaged fetal PQRST-complex is required for the determination of the time intervals. Band pass (1 – 200/500 Hz) filtered raw data is recommended to be used after template or R-peak based averaging. Smoothing filters may be used for template definition and search. To reduce the influe ...
Supraventricular Arrhythmias
Supraventricular Arrhythmias

...  Don’t use in heart transplant ...
Circ editorial
Circ editorial

... determines LV remodeling and the indirect effects of aortic mechanical properties are of secondary importance, but measures of aortic stiffness are also relatively less confounded by the degree of LV dysfunction.12 A Framingham cohort study of 2539 middle-aged to elderly adults followed for a median ...
454 The Cardiovascular System tractions and relaxations of the atria
454 The Cardiovascular System tractions and relaxations of the atria

... decrease rapidly. Diastole starts when the ventricular pressures become lower than the atrial pressures. The pressure difference between the atria and the ventricles then opens the AV valves and blood flows into the relaxed ventricles. Because blood has accumulated in the atria during systole, the v ...
Repair of Post-Infarction Ventricular Free Wall Rupture With TachoSil®
Repair of Post-Infarction Ventricular Free Wall Rupture With TachoSil®

... Raffa et al. (5), in which 6 consecutive patients affected by LVFWR were treated using the TachoSil® patch. All these studies showed promising results. However, the number of patients who have been treated with this technique is still limited. Our study, which is among initial reports of using Tacho ...
Dr - NSUCOMEMS Home
Dr - NSUCOMEMS Home

... Sensation of pain, pressure, burning, tightness. Pain typically near sternum. Occur with dyspnea and anxiety. Related to exercise, cold, stress, meals, emotion. Duration is 30seconds to 20-30 minutes. Relived by NTG Epigastric pain may indicate underlying cardiac disease As people get older, respira ...
Jarvik 2000 Heart
Jarvik 2000 Heart

... after prolonged left ventricular unloading.7,8 Myocyte morphology and metabolism may return to normal in dilated cardiomyopathy, and recovery appears sustainable particularly after myocarditis.9 This has encouraged some centers to pursue mechanical bridge to myocyte recovery as an alternative to car ...
atrial fibrillation
atrial fibrillation

... trial fibrillation (AF) is the most common sustained Symptoms cardiac arrhythmia. The incidence is increasing In some cases AF can be completely without symptoms. in Australia due to the ageing population. It is estimated that 10% of the population older than 75 years Symptoms can range from none to ...
electrical conduction system of the heart
electrical conduction system of the heart

... ▪ This allows for observation of electrical activity in many different parts of the heart ...
A Case of Verapamil-Sensitive Left Ventricular Tachycardia
A Case of Verapamil-Sensitive Left Ventricular Tachycardia

... durations of 150milliseconds, a ventricular rate of 193beats/minute, a right bundle branch morphology, and a right-axis deviation. Unsuccessful attempts were made to convert the patient to sinus rhythm with amiodarone and lidocaine infusions. Laboratory evaluation revealed normal cardiac markers. A ...
Mechanisms of Myocardial Contraction
Mechanisms of Myocardial Contraction

... • ATP Can be generated from either oxidative phosphorylation or glycolysis ...
Arrhythmogenic Right Ventricular Dysplasia: Does my patient have it
Arrhythmogenic Right Ventricular Dysplasia: Does my patient have it

... inversions in anterior or inferior leads • Syncope during or after exercise in young individuals • Palpitations with > 1000 PVCs and abnormal 12 lead ECG • Family history of premature sudden death • Family history of ARVD ...
Ты думаешь, что херово тебе только временно
Ты думаешь, что херово тебе только временно

... Echocardiographic study was carried out in accordance with Feigenbaum’s standard technique by beans of RADMIR (Ultima PRO 30) ultrasonography (Kharkiv, Ukraine). In M-mode the following parameters of the left ventricle were estimated: enddiastolic dimension (cm), end-systolic dimension (cm), thickne ...
First-in-Man Implantation of Left Ventricular
First-in-Man Implantation of Left Ventricular

... approach to the remodeling itself is a mechanical intervention to decrease the LV volume or constrain the ventricle from further enlargement. Several surgical approaches have been advocated in patients with a dilated LV, including partial left ventriculectomy (Batista procedure), cardiomyoplasty, an ...
Buffalo Run Casino Merle Haggard
Buffalo Run Casino Merle Haggard

... with blood, and these have a pressure sensing organ – the carotid sinus – in their walls at about the level of the larynx. External pressure on these carotid sinuses causes the cardiac control centre of the brain to mistakenly assume that the blood pressure has suddenly risen. This leads to a reflex ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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