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Significant reduction of left atrial volume
Significant reduction of left atrial volume

... the basal myocardial septum, and makes it safe and feasible to perform PTSMA.4 Furthermore, this approach improves the clinical and haemodynamic results, and prevents misplacement of ethanol-induced necrosis as a source of potentially fatal complications. Cardiac multidetector CT (MDCT) examination ...
Guidelines for Management of Acute Myocardial Infarction
Guidelines for Management of Acute Myocardial Infarction

... However, a recent trial suggests that culprit vessel-only angioplasty was associated with higher rate of long-term major adverse cardiac event (MACE) compared with multivessel treatment.8 Left main coronary artery primary angioplasty : ACC/AHA has not given any specific recommendation as there is no ...
070 Systole-diastole mismatch in HCM is caused by stress induced
070 Systole-diastole mismatch in HCM is caused by stress induced

... ECG. Heart rate and QRS duration were measured at rest and at peak stress with in-built software. The ST segment shift was measured manually 80 ms after the J point in the lead showing the most change. Echocardiogram. Left ventricular (LV) dimensions, septal and posterior wall thickness, and left at ...
17- interior of heart
17- interior of heart

... Its walls are 3 times thicker than those of the right ventricle. The left ventricular blood pressure is 6 times higher than that inside the right ventricle. In cross section, the left ventricle is circular, the right is crescentic because of the bulging of the ventricular septum into the cavity of t ...
Long Term Follow-up after Mitral Valve Repair in Patients with
Long Term Follow-up after Mitral Valve Repair in Patients with

... survival of 86% (3/21 died)11. The difference in survival is difficult to explain. One possible explanation could be that in the first study the mean follow up was only 13 months, compared to 58 months in our study. Although mitral valve surgery has been performed for many years, valve repair on pat ...
First Degree Atrioventricular Block - e
First Degree Atrioventricular Block - e

... An atrioventricular (AV) block is a common cardiac abnormality. It involves a slowing or blockage of the electrical impulse coming from the sinoatrial (SA) node at or around the AV node (Figure 1). AV blocks are characterized by the slowing or partial or complete blocking of the impulse. This discus ...
Right Ventricular End
Right Ventricular End

... function (LV ejection fraction [LVEF]) undergoing myocardial revascularization, RV hemodynamics were studied from the beginning of anesthesia until the end of the operation [36]. The data were compared with 30 consecutive patients with almost normal LVEF. RVEF was significantly lower in the patients ...
Sleep-Related Breathing Disorders Are Associated With Ventricular
Sleep-Related Breathing Disorders Are Associated With Ventricular

... Patients: Thirty-eight patients with LVEF of 36 ⴞ 13% (mean ⴞ SD) underwent a sleep study. When an apnea-hypopnea index (AHI) > 10/h occurred, SBD was diagnosed. Measurements and results: In patients with SBDs, ventricular arrhythmias (couplets, triplets, short runs) were recorded simultaneously by ...
Circulation: Arrhythmia and Electrophysiology Topic Review
Circulation: Arrhythmia and Electrophysiology Topic Review

... relationship was unchanged after adjustment for clinical characteristics, including left ventricular ejection fraction and natriuretic peptides. In contrast, there was no increased risk of sudden cardiac death in patients with ventricular triplets. In regard to timing of VT, we found that only episo ...
Factors affecting time to arrival in hospital among patients with acute
Factors affecting time to arrival in hospital among patients with acute

... Patients with acute coronary syndromes, including acute myocardial infarction, must be admitted into an Intensive Coronary Care Unit as quickly as possible so as to initiate reperfusion therapy and preserve as much myocardium as possible so as to reduce subsequent morbidity and mortality. Several st ...
Upstream therapeutic strategies of Valsartan and Fluvastatin on
Upstream therapeutic strategies of Valsartan and Fluvastatin on

... Clinical follow-up using standardized questionnaires will be performed every 3 months during the 2 years follow-up period from the assignment of each patient. The dosages and types of all other anti-hypertensive, anti-hyperlipidemia, and anti-arrhythmic drugs used during the follow-up will be record ...
Advances In ResuscitationÑAutomated External Defibrillators
Advances In ResuscitationÑAutomated External Defibrillators

... • Follow the voice prompts and screen messages ...
How to interpret liver function tests in heart failure patients?
How to interpret liver function tests in heart failure patients?

... the right upper quadrant. It is a very useful maneuver for predicting heart failure. Pulsatile liver is generally caused by tricuspid regurgitation, tricuspid stenosis, constrictive pericarditis, restrictive cardiomyopathy, or pulmonary hypertension (17). Splenomegaly is present in a minority of chr ...
Cardiac sarcoma - a fatal disease: report of 2 cases
Cardiac sarcoma - a fatal disease: report of 2 cases

... cava, tricuspid valve). In the case two, the tumor invaded the venous sinus impeding venous returning. The coronary venous sinus involvement was a cause of pericardial effusion by venous engorgement, without effects on venous returning due to the presence of an adequate collateral circulation with a ...
Nocturnal periodic breathing in primary pulmonary hypertension
Nocturnal periodic breathing in primary pulmonary hypertension

... Statistical analysis If not otherwise indicated, all data are presented as mean¡SEM. Patients with and without PB were compared by analysis of variance (ANOVA). This was performed for several parameters (i.e. blood gases, lung function, haemodynamics and polysomnographical variables). Treatment effe ...
Pressure Events of the Cardiac Cycle in the Dog
Pressure Events of the Cardiac Cycle in the Dog

... levels on both sides of the heart. The description of the phases of the cardiac cycle, designated by the alphabetic symbols in figures 1 and 2, largely follows that of Wiggers.1 Atrial contraction begins at A, producing the a wave of the atrial pulse. In the illustrated curves, the end-diastolic pre ...
Congenital Heart Defects
Congenital Heart Defects

... any part of the heart that are present at birth. ...
Downloaded - International Society of Drug Bulletins
Downloaded - International Society of Drug Bulletins

... in over 13,000 patients with stable CHD w10x. The Prevention of Events with Angiotensin Converting Enzyme Inhibition (PEACE) trial enrolled 8290 patients with CHD without evidence of LVSD w11x. No significant difference in death from cardiovascular causes, myocardial infarction, or coronary revascul ...
Clinical and Demographic Characteristics of Patients Presenting
Clinical and Demographic Characteristics of Patients Presenting

... recognized as a major and escalating public health problem 4, and it is one of the most important causes of morbidity and mortality in the world 5. Heart failure is becoming increasingly common in Africa 6, ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... Abstract: IntoductionPrevalence of CHD according to various studies is 8-10 per 1000 live births worldwide.According to status report on CHD ,10% of the present infant mortality in countries may be accounted for by CHD.Pediatric cardiac care in developing countries is still in infancy.MethodsThe pre ...
PDF-link: 200005020123
PDF-link: 200005020123

... lacking a direct connection to the natural cardiocirculatory control loop. The Closed Loop Stimulation of the Inos² CLS pacemaker is a new approach in rate regulation. The Inos² CLS offers the advantage of directly monitoring the action of the natural cardiocirculatory control loop on the myocardium ...
Atrial Septal Defect
Atrial Septal Defect

... heart, other heart defects, if patient’s heart structure won’t allow the device (i.e not enough atrial septal tissue present), active infection anywhere in the body, bleeding disorder or the patient is not suitable for aspirin. • Also important is endocarditis prophylaxis. ...
Adult Congenital Heart Disease and Echocardiography
Adult Congenital Heart Disease and Echocardiography

... aorta (Ao) to the left of the spine and the inferior caval vein (IVC) anterior and to the right. The normal fetal stomach (St) and heart lie on the left side. The second section (C) illustrates the four chambers of the heart with the left atrium (LA) in front of the spine and the right ventricle (RV ...
HEART FAILURE
HEART FAILURE

... Natriuretic Peptides – ANP, BNP • ANP – Atrial Natriuretic Peptide is released from atrial myocyte in response to stretch • ANP is increased in CCF - causes diuresis, natriuresis, vasodilatation, and suppression of Renin – Angiotensin System • BNP – Brain Natriuretic Peptide It is called BNP because ...
The Relationship between Serum Sodium Concentration and Atrial
The Relationship between Serum Sodium Concentration and Atrial

... of persistent AF, which tends to rise as a result of compensatory mechanisms but do not reach the control group Na level, may be the cause of AF by preventing the formation of phase depolarization on the AV node. In this study, patients with paroxysmal atrial fibrillation had low serum Na level than ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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