S. Lee Crystal, Andrew D. Krahn, Yaariv Khaykin, Douglas Cameron
... be attenuated by nonarrhythmic death. We examined the impact of age on device-delivered therapies and outcomes after primary or secondary prevention ICD. Methods and Results—In a prospective, inclusive registry of 5399 ICD recipients in Ontario, Canada (February 2007 to September 2010), device-deliv ...
... be attenuated by nonarrhythmic death. We examined the impact of age on device-delivered therapies and outcomes after primary or secondary prevention ICD. Methods and Results—In a prospective, inclusive registry of 5399 ICD recipients in Ontario, Canada (February 2007 to September 2010), device-deliv ...
What Can We Learn From the RR Intervals Stored in ICDs?
... By recording electrocardiograms (ECG) over an extended period of time, conventional Holter monitors can detect heart rhythm abnormalities that are not continuously present, or can help determine if rhythm disturbances are associated with symptoms. Two common approaches have been widely used for Holt ...
... By recording electrocardiograms (ECG) over an extended period of time, conventional Holter monitors can detect heart rhythm abnormalities that are not continuously present, or can help determine if rhythm disturbances are associated with symptoms. Two common approaches have been widely used for Holt ...
Impact of initial intervention on long term neurological recovey after
... an AED was used, 12 (71%) recovered without major sequelae whereas in the 73 cases where no AED was used, only 34 (47%) had a good outcome (p=0.06). At 6 months follow-up, 46 (51%) survivors had a good outcome (cerebral performance category 1-2), 5 (6%) survived with severe neurological sequelae or ...
... an AED was used, 12 (71%) recovered without major sequelae whereas in the 73 cases where no AED was used, only 34 (47%) had a good outcome (p=0.06). At 6 months follow-up, 46 (51%) survivors had a good outcome (cerebral performance category 1-2), 5 (6%) survived with severe neurological sequelae or ...
Ejection fraction and outcomes in patients with atrial fibrillation and
... rates per 100 person-years in patients with AF and HF, and Supplementary material online, Table S3, shows the same data by EF ranges: ,35%, 35 – 40%, 41 – 49%, and ≥50%. Comparing HFPEF and HFREF patients, there were no statistical differences in stroke, stroke/TE, all-cause death, or bleeding. The ...
... rates per 100 person-years in patients with AF and HF, and Supplementary material online, Table S3, shows the same data by EF ranges: ,35%, 35 – 40%, 41 – 49%, and ≥50%. Comparing HFPEF and HFREF patients, there were no statistical differences in stroke, stroke/TE, all-cause death, or bleeding. The ...
Pharmacology
... activation. Maintained depolarisation, as in ischaemic muscle, causes channels to change more slowly from open to refractory (inactivation), and the membrane must then be repolarised for a time to restore the channel to the resting state before it can be activated again. Therefore, these drugs show ...
... activation. Maintained depolarisation, as in ischaemic muscle, causes channels to change more slowly from open to refractory (inactivation), and the membrane must then be repolarised for a time to restore the channel to the resting state before it can be activated again. Therefore, these drugs show ...
Transthoracic three-dimensional echocardiography in adult
... visualization of the mitral valve from above allowed comprehensive assessment of leaflet motion, area orifice and shape and commissure morphology. In patients with mitral stenosis, leaflet involvement and orifice narrowing could be evaluated from the atrial side. Both the site and extent of mitral v ...
... visualization of the mitral valve from above allowed comprehensive assessment of leaflet motion, area orifice and shape and commissure morphology. In patients with mitral stenosis, leaflet involvement and orifice narrowing could be evaluated from the atrial side. Both the site and extent of mitral v ...
Proportion of Heart Failure Patients who Meet Criteria for
... In the United States, an estimated 5.8 million people are diagnosed with heart failure including 550,000 new cases diagnosed each year. Heart failure also places significant financial load on the nation, contributing $39 billion dollars annually in health care services.1 The American College of Card ...
... In the United States, an estimated 5.8 million people are diagnosed with heart failure including 550,000 new cases diagnosed each year. Heart failure also places significant financial load on the nation, contributing $39 billion dollars annually in health care services.1 The American College of Card ...
Heart Functions: the MEA and the Frank Starling Law of the heart 2/14
... Heart Functions: the ECG and the MEA Feb 10 • How does one calculate heart rate, RR interval, PR interval and ST interval from an ECG? • How do these values change pathologically? • What leads are used to evaluate the heart during intensive care? • What does the MEA tell us about heart function? • W ...
... Heart Functions: the ECG and the MEA Feb 10 • How does one calculate heart rate, RR interval, PR interval and ST interval from an ECG? • How do these values change pathologically? • What leads are used to evaluate the heart during intensive care? • What does the MEA tell us about heart function? • W ...
Redalyc.Cuba`s National Pediatric Cardiology Program
... detected heart disease, hospital admission to pediatric cardiology, neonatal, or intensive care units. Adults with congenital heart disease, regardless of age at detection, type of treatment or stage of rehabilitation, also come under the care of the provincial pediatric cardiology team and may be r ...
... detected heart disease, hospital admission to pediatric cardiology, neonatal, or intensive care units. Adults with congenital heart disease, regardless of age at detection, type of treatment or stage of rehabilitation, also come under the care of the provincial pediatric cardiology team and may be r ...
Heart Failure With Normal Left Ventricular Ejection Fraction
... applied (12). Compared with patients with HF and reduced LVEF, individuals with HFNEF are typically older and more likely to be women, together with a higher likelihood of hypertension (prevalence up to 88% [13]), obesity (prevalence of body mass index ⬎30 kg/m2 typically approximately 40% [11,13]), ...
... applied (12). Compared with patients with HF and reduced LVEF, individuals with HFNEF are typically older and more likely to be women, together with a higher likelihood of hypertension (prevalence up to 88% [13]), obesity (prevalence of body mass index ⬎30 kg/m2 typically approximately 40% [11,13]), ...
26 Recent Advances in Nuclear Cardiology
... regional wall motion abnormalities (RWMA), has become a routine part of clinical protocols, expanding the clinical utility of MPI. Recent American College of Cardiology/American Heart Association/American Society of Nuclear Cardiology guidelines for the clinical use of cardiac radionuclide imaging ...
... regional wall motion abnormalities (RWMA), has become a routine part of clinical protocols, expanding the clinical utility of MPI. Recent American College of Cardiology/American Heart Association/American Society of Nuclear Cardiology guidelines for the clinical use of cardiac radionuclide imaging ...
BIOLOGY 2060 LECTURE NOTES
... Cardiac cycle = Refers to all events associated with blood flow thru the heart during one heartbeat. a. Includes the contraction (systole) and relaxation (diastole) of all 4 chambers. b. Divided into 4 parts: ventricular filling, isovolumetric contraction, ventricular ejection, and isovolume ...
... Cardiac cycle = Refers to all events associated with blood flow thru the heart during one heartbeat. a. Includes the contraction (systole) and relaxation (diastole) of all 4 chambers. b. Divided into 4 parts: ventricular filling, isovolumetric contraction, ventricular ejection, and isovolume ...
L14 The Cardiac Cycle copy 2
... I can label the main parts of the heart and describe the circulation of blood flow round the body ...
... I can label the main parts of the heart and describe the circulation of blood flow round the body ...
Full Text-1 - African Index Medicus
... expression and varied clinical course.(2,3,5,6,8,9) This disease ...
... expression and varied clinical course.(2,3,5,6,8,9) This disease ...
The SAMe-TT2R2 score and quality of anticoagulation in AF: Can
... The quality of anticoagulation is the result of a dynamic process with potential for rapid and long-term variation within the single patient in relation to compliance, health status or intercurrent disease. An inherent problem of the SAMe-TT2R2 score is the assumption that a fixed set of patient cha ...
... The quality of anticoagulation is the result of a dynamic process with potential for rapid and long-term variation within the single patient in relation to compliance, health status or intercurrent disease. An inherent problem of the SAMe-TT2R2 score is the assumption that a fixed set of patient cha ...
Cardiovascular System: Heart
... Changes in heart rate also produce changes in cardiac contractility Example: Increase in heart rate = Increase in cardiac contractility 1) heart rate = APs per unit time = total amount of Ca2+ entering cell per unit time AND 2) Ca2+ entering cell per unit time = accumulation of Ca2+ in SR ...
... Changes in heart rate also produce changes in cardiac contractility Example: Increase in heart rate = Increase in cardiac contractility 1) heart rate = APs per unit time = total amount of Ca2+ entering cell per unit time AND 2) Ca2+ entering cell per unit time = accumulation of Ca2+ in SR ...
Cardiovascular System: Heart
... • ACh decreases inward Ca2+ current during plateau 1) Cardiac glycosides inhibit Na+-K+ ATPase ...
... • ACh decreases inward Ca2+ current during plateau 1) Cardiac glycosides inhibit Na+-K+ ATPase ...
Cardiovascular System: Heart
... Changes in heart rate also produce changes in cardiac contractility Example: Increase in heart rate = Increase in cardiac contractility 1) heart rate = APs per unit time = total amount of Ca2+ entering cell per unit time AND 2) Ca2+ entering cell per unit time = accumulation of Ca2+ in SR ...
... Changes in heart rate also produce changes in cardiac contractility Example: Increase in heart rate = Increase in cardiac contractility 1) heart rate = APs per unit time = total amount of Ca2+ entering cell per unit time AND 2) Ca2+ entering cell per unit time = accumulation of Ca2+ in SR ...
Gene Therapy in Large Animal Models of Human Cardiovascular
... Definition and Classification of Cardiomyopathies recommended updating its classification system to better reflect the current understanding of the etiology and pathogenesis of cardiomyopathies, which are now classified by dominant pathophysiology (Richardson et al. 1996). Dilated cardiomyopathy may ...
... Definition and Classification of Cardiomyopathies recommended updating its classification system to better reflect the current understanding of the etiology and pathogenesis of cardiomyopathies, which are now classified by dominant pathophysiology (Richardson et al. 1996). Dilated cardiomyopathy may ...
Ratio trabecular and compact myocardium in the wall of the left
... ventricles. In all cases HLHS accompanied by ventricular fibroelastosis. Structural move hearts with myocardial fibers HLHS had direction, as in normal hearts. Found that on top of the left ventricle, in the hearts of number 1, 2 absolute thickness of the compact myocardium (CM) is two times higher ...
... ventricles. In all cases HLHS accompanied by ventricular fibroelastosis. Structural move hearts with myocardial fibers HLHS had direction, as in normal hearts. Found that on top of the left ventricle, in the hearts of number 1, 2 absolute thickness of the compact myocardium (CM) is two times higher ...
heart sounds
... 2) Triple or gallop rhythm: Def., It is an abnormal condition in which three heart sound are heard resembling the sound of a galloping ...
... 2) Triple or gallop rhythm: Def., It is an abnormal condition in which three heart sound are heard resembling the sound of a galloping ...
heart sounds practical section
... 2) Triple or gallop rhythm: Def., It is an abnormal condition in which three heart sound are heard resembling the sound of a galloping ...
... 2) Triple or gallop rhythm: Def., It is an abnormal condition in which three heart sound are heard resembling the sound of a galloping ...
Influence of right ventricular pacing on right ventricular systolic
... and improves the quality of life of the population. Yet, one of the possible side effects is worsening of the systolic function of the left ventricle (LV). This question has been discussed for more than 20 years. 14 randomized trials were performed, of which, some suggest a negative influence of the ...
... and improves the quality of life of the population. Yet, one of the possible side effects is worsening of the systolic function of the left ventricle (LV). This question has been discussed for more than 20 years. 14 randomized trials were performed, of which, some suggest a negative influence of the ...
Exercise-Induced Left Ventricular Systolic Dysfunction in Women
... However, this approach can suffer from limited sensitivity.15 It is known that some women heterozygous for dystrophinopathy progress to overt syndromic cardiomyopathy, but they probably represent a minority. Indeed, Holloway et al16 reported several instances of early cardiopulmonary death (at ages ...
... However, this approach can suffer from limited sensitivity.15 It is known that some women heterozygous for dystrophinopathy progress to overt syndromic cardiomyopathy, but they probably represent a minority. Indeed, Holloway et al16 reported several instances of early cardiopulmonary death (at ages ...
المحاضرة 06 حسابات وأرقام زمنية فى رسم القلب
... Disadvantage of Bazett's formula is not giving correct results at high heart rates. To give a simple rule of thumb: if the observed QT interval on the ECG is more than 1/2 half of the RR interval at least consider the possibility of prolonged QT interval. It is recommended to observe QT interval in ...
... Disadvantage of Bazett's formula is not giving correct results at high heart rates. To give a simple rule of thumb: if the observed QT interval on the ECG is more than 1/2 half of the RR interval at least consider the possibility of prolonged QT interval. It is recommended to observe QT interval in ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.