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Cardiology Review
Cardiology Review

... • Conservative:   Fluid restriction & Diuretics • Hemodynamically significant PDA  • Indomethacin/Ibuprofen  • Surgical Ligation ...
Haemodynamic Learning Package
Haemodynamic Learning Package

... The right atrial or CVP waveform usually consists of 3 positive waves, the “a”, “c”, and “v” waves. The a wave is followed by the “x” descent whilst the c and v waves are followed by the “x” and “y” descents respectively. (see illustration). The positive deflections represent; A wave - represents at ...
Experimental Study of the so Called Left Ventricular Isovolumic
Experimental Study of the so Called Left Ventricular Isovolumic

... the anterior aspect of left ventricle, between the first and second diagonal branches of the anterior descending artery and parallel to the anterior descending artery toward the aortic root, in a zone corresponding to the ascending segment of the apical loop (P3) (Figure 1). The pairs of microcrysta ...
UKRAINIAN MINISTRY OF HEALTH CARE
UKRAINIAN MINISTRY OF HEALTH CARE

... Despite thiazides being cheap, effective, and recommended as the best first-line drug for hypertension by many experts, they are not prescribed as often as some newer drugs. Arguably, this is because they are off-patent and thus rarely promoted by the drug industry.[8] Physicians may start with non- ...
Takotsubo cardiomyopathy and the long-QT syndrome
Takotsubo cardiomyopathy and the long-QT syndrome

... mutations implicated in the congenital LQTS or may harbour multiple common population variants that impair the repolarization reserve in more subtle ways.17 They may also have other predisposing abnormalities such as structural cardiac disease, metabolic disease, or bradycardia.17 There has been lit ...
CV Lecture 2
CV Lecture 2

... –  Sharp volume increase; levels off as pressure gradient decreases –  Active phase - atria contract –  Pressure in ventricle increases because extra blood is forced in –  Volume in ventricle increases Allied Science Physiology. Cardiovascular System. Lecture 2. ...
2.Heart as Pump - Notes For ANZCA Primary Exam
2.Heart as Pump - Notes For ANZCA Primary Exam

... o Begins with closure of aorta & pulmon valves (2 heart sound – may be split if aortic closes 1st) o Incursura in aortic pressure waveform produced by closure of valve causing brief backflow of blood o Atrial pressures: LA ~5mmHg; RA ~2mmHg o Ends when vent pressure falls below atrial pressure ⇒ mit ...
TEMPORARY PACING – WHEN AND HOW? DR. R. VIJAYAKUMAR
TEMPORARY PACING – WHEN AND HOW? DR. R. VIJAYAKUMAR

... Pace maker is an artificial device that delivers a timed fixed electrical stimulus to the heart, which results in cardiac depolarisation. These devices keep the heart beating slow when used. The main disadvantage is that they cannot control a faster rate. The indication for temporary pacing can be c ...
The Second Heart Sound
The Second Heart Sound

... systolic click may vary its location in systole with certain maneuvers that change the shape of the left ventricle (see Chapter 26, Systolic Murmurs) . The best way to differentiate an A2-P 2 from an A2 OS is to have the patient stand up . The A 2P2 interval remains the same or narrows, whereas the ...
Arrhythmogenic right ventricular cardiomyopathy in a dog
Arrhythmogenic right ventricular cardiomyopathy in a dog

... signs, until acutely decompensated congestive right heart failure led to euthanasia after 4 months. Arrhythmogenic right ventricular cardiomyopathy is a well-described clinical entity in humans, and has previously been documented in 3 male dogs. The condition is characterised by progressive fibro-ad ...
acute myocardial infarction in an elderly patient with severe aortic
acute myocardial infarction in an elderly patient with severe aortic

... fibrosis12 and reduced capillary ingrowth into the hypertrophied myocardium4. Additionally, the increased filling pressure needed to distend the thickened ventricular wall compresses the endocardium, further impairing blood flow to that layer of the myocardium. These abnormalities may contribute to ...
Is our heart a well-designed pump? The heart along animal evolution
Is our heart a well-designed pump? The heart along animal evolution

... systems are peristaltic tubes pushing slowly the haemolymph into an open vascular tree without capillaries (worms). Arthropods developed contractile bulges on the abdominal aorta assisted by accessory hearts for wings or legs and by abdominal respiratory motions. Two-chamber heart (atrium and ventri ...
Gender Differences in Electrophysiological
Gender Differences in Electrophysiological

... IVTs are usually classified into three groups according to the site of their origin: IVT from right ventricular outflow tract (RVOT-VT), IVT from left ventricular outflow tract and Fascicular IVT. RVOT-VT is a common arrhythmia in young patients without any structural heart disease. The arrhythmia i ...
Case study: Segementel approach to complex congenital cardiac
Case study: Segementel approach to complex congenital cardiac

...  ASD, VSD, size of the ventricles, and the presence and degree of any ventricular outflow tract stenosis.  The aorta and pulmonary artery also should be carefully examined for evidence of hypoplastic and stenotic lesions (eg, aortic coarctation and hypoplasia of the aortic arch) + PDA. ...
ARRHYTHMIAS IN CHILDREN
ARRHYTHMIAS IN CHILDREN

... accessory fascicle can be localized. Emergency treatment in SVPT crisis  The first administered drug is adenosine in dose of 0,1 mg/kg.  In the case of administration through peripherial vein by small diameter, the dose can be slightly increased to 0,15 mg/kg, with possibility to repeat the dose o ...
Long-Term Outcome of Outlet-Type Ventricular Septal Defect: Focus
Long-Term Outcome of Outlet-Type Ventricular Septal Defect: Focus

... media. 23,24 The Venturi effect is defined as a highvelocity jet flow of blood created by the VSD below the aortic valve. This effect has been considered as the most probable cause of AVP25,26 because such a high-velocity jet flow is potentially capable of progressive elongation of the adjacent aort ...
Moderate to large VSDs
Moderate to large VSDs

...  As a result of the higher aortic pressure, blood shunts left to right through the ductus, from the aorta to the pulmonary artery.  If the PDA is small, pressure within the pulmonary artery, the right ventricle, and the right atrium is normal.  If the PDA is large pulmonary artery pressure may be ...
Hemodynamic Consequences of the Injection of Radiopaque Material
Hemodynamic Consequences of the Injection of Radiopaque Material

... ANGIOCARDIOGRAPHY and cineangiocardiography are employed with increasing frequency for the diagnosis of cardiovascular diseases. These commonplace technics of cardiovascular radiology depend upon the rapid injection of radiopaque materials into the heart or central circulation. A wide variety of sub ...
Continuous heart murmur: a sign of inestimable value
Continuous heart murmur: a sign of inestimable value

... can cause a complete heart block which can cause death or syncope29. This disorder is often linked to other congenital defects, primarily with interventricular communication, most often in type I or supracrestal30 it may also be associated with aortic regurgitation (41.9%), pulmonary stenosis (9.7%) ...
Patient information sheet – Ablation of arrhythmias
Patient information sheet – Ablation of arrhythmias

... heart) reaching the ventricle. After an AV node ablation your heart will no longer be able to “race” or beat fast. Actually the heart rate will be very slow and therefore a permanent pacemaker will need to be inserted to maintain a regular and stable heart rate. The pacemaker will usually be implant ...
Different effect of exercise on left ventricular diastolic time and
Different effect of exercise on left ventricular diastolic time and

... ejection and total LV systole (10,11). This effect of loading conditions on the duration of LV systole is a well documented finding in cardiac disease states with considerable afterload-mismatch as aortic stenosis and hypertrophic obstructive cardiomyopathy (12,13). The end-diastolic volume increase ...
Intra-aortic Balloon Counterpulsation: Indications and pitfalls
Intra-aortic Balloon Counterpulsation: Indications and pitfalls

... 4. Be able to troubleshoot suboptimal IABP settings, particularly those related to  timing, filling, and triggering.   ...
Aging and the Cardiovascular System
Aging and the Cardiovascular System

... described by the term atherosclerosis. Arteriosclerosis results in stiffening of the large arteries and an increase of pulse wave velocity (PWV), which is a reliable and widely used index of arterial stiffening. 32,33 Changes in the shape of the arterial waveform also occur.34 These changes are main ...
Cardiac Morphology and Blood Pressure in the Adult Zebrafish
Cardiac Morphology and Blood Pressure in the Adult Zebrafish

... arteriosus was located anterior to the ventricle, and functioned as an elastic reservoir to absorb the rapid rise of pressure during ventricular contraction. The dense matrix of collagen interspersed across the entire bulbus arteriosus exemplified the characteristics of vasculature smooth muscle. Th ...
Pdf version - Polish Archives of Internal Medicine
Pdf version - Polish Archives of Internal Medicine

... cardial viability characteristics for predicting long­‑term response to CRT. Patients and methods   ViaCRT was a prospective multicenter study involving 127 patients with heart failure. Cardiac dyssynchrony indices and low­‑ dose dobutamine response were determined by echocar‑ diography prior to CRT ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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