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2009 - Laboratory Animal Boards Study Group
2009 - Laboratory Animal Boards Study Group

... The purpose of the study was to determine the prevalence of various radiographic abnormalities in cats with FBD, to evaluate intra- and interobserver variability in radiographic interpretation, and to determine whether variability in radiographic interpretation was associated with experience of the ...
Clinical recommendations of cardiac magnetic resonance, Part I
Clinical recommendations of cardiac magnetic resonance, Part I

... Black-blood Fast Spin Echo (FSE) or double-inversion recovery FSE, with proton density or T1-weighting are used to evaluate cardiac morphology and to detect fat, which shows hyperintense signal on T1-weighted images. Conventional T1 and T2-weighted FSE (or double-inversion recovery FSE) can be obtai ...
Functional Morphology of the Heart in Fishes D. J. Randall
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... son shark are incompetent in the absence mean blood flow is 15 ml/minute, and the of conal systole, and it appears that con- period of time when the maintenance of tractions of the conus do not aid the blood flow in the ventral aorta is due to the ventricle in forcing blood into the ventral elastic ...
iatrogenic left main coronary artery stenosis after aortic valve
iatrogenic left main coronary artery stenosis after aortic valve

... location and rapid evolution. Prompt diagnosis and treatment are essential for the patient’s survival. The usual clinical picture includes severe angina, ventricular arrhythmias, congestive heart failure and sudden death. It usually appears within the first six months but may occur up to thirty mont ...
clinically applicable alternative to Emax
clinically applicable alternative to Emax

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Automated external defibrillators: What`s established? What`s new?
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... Approximately 1.000 people in the United States suffer from cardiac arrest each day, ...
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Rheumatic fever
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Trying to succeed when the right ventricle fails

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... burden of morbidity and mortality, of which thalassaemia is the commonest single gene disorder worldwide [1]. The transfusions that are necessary for survival cause tissue iron loading, and this ultimately results in heart failure as the major cause of death [2, 3]. Histopathological studies of pati ...
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... these patients have invasive or non-invasive evidence of abnormal diastolic function (either abnormal relaxation, filling or stiffness) they are said to have ‘‘diastolic HF’’.3 Although the term ‘‘HF with normal LVEF’’ is often used to denote this group, because ‘‘normal’’ is variously defined, ‘‘HF ...
Reading an athlete`s ECG: from ESC to Seattle and beyond
Reading an athlete`s ECG: from ESC to Seattle and beyond

... Isolated increase of QRS voltages •  According to the ESC recommendation for athlete’s ECG interpretation, the ECG changes due to cardiac adaptation to physical exertion, predominantly the physiologic increase of QRS voltages, should not cause alarm and the athlete should be allowed to participate ...
Sudden Cardiac Death: Exploring the Limits of Our Knowledge
Sudden Cardiac Death: Exploring the Limits of Our Knowledge

... statement of medical and public health progress.1 0 During the same period of time, there was a marked reduction in early mortality from acute myocardial infarction, initially thought to be related to the development of the coronary care unit and its effect on electrical and, to a more limited exten ...
valve replacement for acute left heart endocarditis
valve replacement for acute left heart endocarditis

... predominance, the morbidity and mortality from cardiac failure are greater with aortic valve infective endocarditis than with mitral valve involvment and can reach 50 to 90% if treated by medical therapy alone (11). With our patients, emboli occured in 12 cases, and persistent sepsis occured in 19 p ...
Impact of Longitudinal Myocardial Deformation on the Prognosis of
Impact of Longitudinal Myocardial Deformation on the Prognosis of

... we demonstrated that longitudinal global strain (by speckle tracking) is superior to LVEF, SR, and tissue Doppler imaging in predicting outcome in HF patients. This information highlights the importance to evaluate the impact of medical decision (device implantation and valvular replacement) based o ...
12 Lead ECG Interpretation * Part 3
12 Lead ECG Interpretation * Part 3

... • Q wave must be more than 40ms wide (0.04sec) or a third the R wave height to be pathological ...
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Distribution of late gadolinium enhancement in various types of

... The diagnosis of patients with NICM originates with the differentiation of ICM. In general, coronary angiography is routinely performed for the differentiation, and when patients have no obstructive coronary arteries or coronary risk factors, the diagnosis of NICM is usually made. However, it has to ...
A practical approach to perioperative
A practical approach to perioperative

... Group.(4) The code consists mainly of three letters, which denote the chamber being paced, chamber where the sensing of intrinsic cardiac signals occurs and response to sensed intrinsic signals, respectively. AOO, VOO and DOO modes indicate asynchronous pacing, in which pacing stimuli is delivered r ...
Blood Velocity and Endocarditis
Blood Velocity and Endocarditis

... at this site would thus be perfused with a fluid despoiled of its oxygen and nutrients and surcharged with accumulated metabolic end-products. Retrograde perfusion also may diminish the facility with which leukocytes, antibodies, and antibiotics can enter the site, and may contribute to the deformat ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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