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2016 prephd course work study material on development of BPN
2016 prephd course work study material on development of BPN

... recognition successes of the Twentieth Century. It certainly sounds more exciting than a technical description such as “A network of weighted, additive values with nonlinear transfer functions”. However, despite the name, neural networks are far from “thinking machines” or “artificial brains”. A typ ...
Document
Document

... head, it is the point in the eye where the optic nerve fibers leave the retina. Commonly referred to as the “blind spot,” for centuries it has been assumed to have no photoreceptor cells to respond to light stimuli. This assumption requires closer examination. The principal view assumes the existenc ...
Synapse Elimination and Remodeling
Synapse Elimination and Remodeling

... starts after birth and continues throughout life. • Synapse elimination is an important component of development, as many more synapses are formed than would be present in the adult animal. • Most often, these changes are related to adjustments in the number and strength of synaptic connections (“fi ...
Embryological origin for autism
Embryological origin for autism

... underlying autism Several quantitative changes have been observed in autistic brains at autopsy. An elevation of about 100 g in brain weight has been reported (Bauman and Kemper, 1985). While attempts to find anatomical changes in the cerebral cortex have been unsuccessful (Williams et al., 1980; Co ...
NEUROGENESIS Y PLASTICIDAD DEL HIPOCAMPO ADULTO
NEUROGENESIS Y PLASTICIDAD DEL HIPOCAMPO ADULTO

... Deisseroth, Nat Methods 2010 ...
Study guide (Word Document)
Study guide (Word Document)

... potentially relevant. However, my questions will not be taken word-for-word from the lab manual. If an idea is addressed by a lab manual question, you should be able to access that knowledge even if I phrase the question in a different way! In addition, you may need to tie together information from ...
Cation-Chloride Cotransporters and Neuronal Function
Cation-Chloride Cotransporters and Neuronal Function

... Ion trafficking across biological membranes is mediated by channels and transporters, and these two types of molecules form the basis of electrical signaling in the nervous system. However, the volume of research on voltage- and ligand-gated channels is orders of magnitude higher than what has been ...
Dynamic computation in a recurrent network of heterogeneous
Dynamic computation in a recurrent network of heterogeneous

... of the clusters are unconstrained and have an equal likelihood of existing at any position. Therefore, clusters in a homogeneous network move in a random walk, constrained only by their interactions with nearby clusters [1]. In contrast, networks with heterogeneous neurons tend to bias the locations ...
Encoding of Action History in the Rat Ventral Striatum
Encoding of Action History in the Rat Ventral Striatum

... rewards expected in the future are referred to as value functions, and actions are chosen so as to maximize a long-term sum of positive outcomes based on the value functions. At each time step, the actual reward received by the animal is compared with the reward expected based on the value functions ...
In vivo two-photon calcium imaging of neuronal networks
In vivo two-photon calcium imaging of neuronal networks

... Over the years these techniques have been used extensively for studying different aspects of brain function and have led to the discovery of important macroscopic features of processing networks, such as, for example, the orientation preference map in the visual cortex (7). However, many aspects of ...
BvP neurons exhibit a larger variety in statistics of inter
BvP neurons exhibit a larger variety in statistics of inter

... of the neuron. It is known that the spiking mechanisms of regularly spiking neurons can be classified into two classes, Class I and Class II, according to their bifurcation structures in response to a constant current injection.3, 4) Regularly spiking neurons discharge spikes regularly, at a constan ...
Polarization-sensitive and light-sensitive neurons in two parallel
Polarization-sensitive and light-sensitive neurons in two parallel

... component of an internal compass signal. A recent anatomical study in the locust suggests that a small area in the brain, the anterior optic tubercle (AOTu), is a relay station in the neural pathway from polarization-sensitive photoreceptors to the central complex (Homberg et al. 2003; Fig. 1A). We ...
Matching mind to world and vice versa: Functional dissociations
Matching mind to world and vice versa: Functional dissociations

... Observing a stranger walk into a bakery can automatically trigger a rapid understanding of the different mental states pertaining to this action, such as the stranger’s belief (that she can purchase food in the bakery) and her desire (to satisfy her sweet tooth). Observing the stranger leave the bak ...
Theroleofdendritesinauditory coincidence detection
Theroleofdendritesinauditory coincidence detection

... may be understood. Our results show that, in these neurons, the cell morphology and the spatial distribution of the inputs enrich the computational power of these neurons beyond that expected from ‘point neurons’ (model neurons lacking dendrites). Over the past 40 years it has become widely accepted ...
Mirror Proposal 8-01 - USC - University of Southern California
Mirror Proposal 8-01 - USC - University of Southern California

... recognition of the same action executed by another. Analysis of this system has major implications for the understanding of imitation and language in humans, but the focus of the present proposal is a new theory of the brain mechanisms underlying action recognition in monkeys. We will explore this b ...
Dynamics  of  Learning  and  Recall ... Recurrent  Synapses and  Cholinergic Modulation
Dynamics of Learning and Recall ... Recurrent Synapses and Cholinergic Modulation

... play a dominant role in determining the information processing characteristics of this region. However, they result in feedback dynamics that may cause both runaway excitatory activity and runaway synaptic modification. Previous models of recurrent excitation have prevented unbounded activity using ...
Multiple Representation in Primate SI
Multiple Representation in Primate SI

... 1.2 Hierarchical Relationship between Areas 3b and 1 Numerous studies suggest a hierarchical relationship between Area 3b and Area 1. Ablations of Area 3a and 3b leave Area 1 unresponsive, consistent with anatomy studies that show that Area 1 receives the bulk of its input from Area 3b. These findin ...
Cautionary Observations on Preparing and Interpreting Brain
Cautionary Observations on Preparing and Interpreting Brain

... for certain purposes, it can in some cases be a disadvantage for visualizing the whole morphology of the labeled neurons. To reveal the entire cellular morphology, the antibody should recognize an antigen that is distributed evenly throughout all parts of the labeled cells. But this is often not the ...
Function of the spinal cord, cerebellum and brain stem
Function of the spinal cord, cerebellum and brain stem

... be associated with a deficiency in the cerebellum. Patients with cerebellar lesions (injuries) typically exhibit "intention tremors"—a tremor occurring during movement rather than at rest (as seen in Parkinson's disease). Patients may also show dysmetria, i.e., an overestimation or underestimation o ...
Biological Rhythms: 2 Day Circadian Examples Biorhythms
Biological Rhythms: 2 Day Circadian Examples Biorhythms

... • Retinal blindness can disturb resetting if it affects these ganglion cells • Some blind individuals have “free-running rhythms” for this reason. • But under normal conditions our internal clock itself is very resistant to disruption. ...
Stop-Signal Task - Gemstone Honors Program
Stop-Signal Task - Gemstone Honors Program

... shown to reduce ADHD symptoms in patients (Weisler, 2005). The impact of Adderall® on neurotransmitters has been established through previous research; however, its impact on neural firing in relation to impulsivity is yet unexamined. Neural firing in a specific brain region during a task demonstrat ...
Lecture 11 - Fredonia.edu
Lecture 11 - Fredonia.edu

... •Produce differential electrical signals when plate is deformed by external forces •Used to study lip & jaw movement ...
cp_kellermann_launay_17092010
cp_kellermann_launay_17092010

... neurotransmitters essential for communication between neurons and particularly involved in eating and sexual behaviours, the sleep-wake cycle, pain, anxiety and mood problems. Strategies employing antidepressant class I molecules, developed since the 1960s are thus primarily aimed at increasing the ...
LTP
LTP

... Original LTP Study • By Timothy Bliss and Terje Lomo (1973) • Done on an anaesthetized rabbit’s hippocampus • Brief, high-frequency stimulation of the perforant pathway input to the dentate gyrus produced a long lasting enhancement of the extracellular ...
Poster
Poster

... The hippocampus, a major component of the vertebrate brain, functions in memory and is one of the first regions of the brain to show damage in Alzheimer’s disease (AD). AD is a progressive neurologic disorder that interferes with memory and learning. ...
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Metastability in the brain

In the field of computational neuroscience, the theory of metastability refers to the human brain’s ability to integrate several functional parts and to produce neural oscillations in a cooperative and coordinated manner, providing the basis for conscious activity.Metastability, a state in which signals (such as oscillatory waves) fall outside their natural equilibrium state but persist for an extended period of time, is a principle that describes the brain’s ability to make sense out of seemingly random environmental cues. In the past 25 years, interest in metastability and the underlying framework of nonlinear dynamics has been fueled by advancements in the methods by which computers model brain activity.
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