 
									
								
									Quinine toxicity identified after 40 years
									
... nor was there any history of systemic medical diseases or vascular events such as severe bleeding, operation or hypotension that would give rise to bilateral CRVO or CRAO. Before we considered further investigations, we decided to review her history again with direct questions. This time she finally ...
                        	... nor was there any history of systemic medical diseases or vascular events such as severe bleeding, operation or hypotension that would give rise to bilateral CRVO or CRAO. Before we considered further investigations, we decided to review her history again with direct questions. This time she finally ...
									PRODUCT MONOGRAPH Pr INDERAL®-LA (Propranolol
									
... There may be increased difficulty in treating an allergic type reaction in patients on betablockers. In these patients, the reaction may be more severe due to the pharmacological effects of beta-blockers and problems with fluid changes. Epinephrine should be administered with caution, since it may ...
                        	... There may be increased difficulty in treating an allergic type reaction in patients on betablockers. In these patients, the reaction may be more severe due to the pharmacological effects of beta-blockers and problems with fluid changes. Epinephrine should be administered with caution, since it may ...
									Disintegration of Tablets and Capsules Measured by Isothermal
									
... Figure 1TMA vs Real World Disintegration Measurements ............................................ 44 Figure 2Schematic Diagram of TMA ............................................................................... 45 Figure 3 Modified TMA Apparatus .................................................. ...
                        	... Figure 1TMA vs Real World Disintegration Measurements ............................................ 44 Figure 2Schematic Diagram of TMA ............................................................................... 45 Figure 3 Modified TMA Apparatus .................................................. ...
									In vitro and in vivo studies of artemisinin endoperoxides
									
... derived from the Chinese medicinal herb qinghao (Artemisia annua L.). This plant has been used in traditional Chinese medicine for more than 2000 years in the treatment of fever, but it was not until 1972 that the active antimalarial moiety, artemisinin, was isolated from the leaves and the structur ...
                        	... derived from the Chinese medicinal herb qinghao (Artemisia annua L.). This plant has been used in traditional Chinese medicine for more than 2000 years in the treatment of fever, but it was not until 1972 that the active antimalarial moiety, artemisinin, was isolated from the leaves and the structur ...
									Eco-directed sustainable prescribing
									
... jeopardizing the quality of delivered health care if prescribing guidelines are altered. Long-deemed infeasible has been the optimization of the therapeutic use of medications for preventing pollution at its source. This stance, however, has been shown to be unfounded in at least one instance, where ...
                        	... jeopardizing the quality of delivered health care if prescribing guidelines are altered. Long-deemed infeasible has been the optimization of the therapeutic use of medications for preventing pollution at its source. This stance, however, has been shown to be unfounded in at least one instance, where ...
									[Salvia divinorum - a potential drug for abuse]
									
... documented, and these could easily result in risk to individuals. As noted above, these effects include: altered perception, hallucinations, ataxia, depersonalization, incoherent speech and unconsciousness in humans (Siebert DJ, 1994). Additionally, given that its pharmacological action (kappa-opioi ...
                        	... documented, and these could easily result in risk to individuals. As noted above, these effects include: altered perception, hallucinations, ataxia, depersonalization, incoherent speech and unconsciousness in humans (Siebert DJ, 1994). Additionally, given that its pharmacological action (kappa-opioi ...
									Dosage Calculations INTRODUCTION
									
... ✘ qd—the frequency ✓ 4 oz—the quantity dispensed ✘ Prozac® Solution 20 mg/5 mL—the drug name and strength ✘ 120 mL—the quantity of the stock bottle The question is simply asking how many doses make up the total amount being dispensed. The strength of the drug, frequency of dosage and quantity of the ...
                        	... ✘ qd—the frequency ✓ 4 oz—the quantity dispensed ✘ Prozac® Solution 20 mg/5 mL—the drug name and strength ✘ 120 mL—the quantity of the stock bottle The question is simply asking how many doses make up the total amount being dispensed. The strength of the drug, frequency of dosage and quantity of the ...
									the scientific value of non-clinical animal studies in drug development
									
... of animal studies, which is that it is a living model system that is being used to extrapolate results from. Animal model systems have high intrinsic variability, immutable differences within species and are also mechanistically not completely understood(17). Study design can influence all three fac ...
                        	... of animal studies, which is that it is a living model system that is being used to extrapolate results from. Animal model systems have high intrinsic variability, immutable differences within species and are also mechanistically not completely understood(17). Study design can influence all three fac ...
									Effect of compression force, humidity and disintegrant concentration
									
... Purpose: The effect of compression force, relative humidity and disintegrant concentration on furosemide dissolution in directly compressed furosemide/Avicel-tablets was studied. Methods: Mixtures of furosemide (12.5% w/w), Ac-Di-Sol (0, 0.625% to 10% w/w) and Avicel PH200 (qs to 100% w/w) were p ...
                        	... Purpose: The effect of compression force, relative humidity and disintegrant concentration on furosemide dissolution in directly compressed furosemide/Avicel-tablets was studied. Methods: Mixtures of furosemide (12.5% w/w), Ac-Di-Sol (0, 0.625% to 10% w/w) and Avicel PH200 (qs to 100% w/w) were p ...
									ULTRACET C IV
									
... involve more than one acetaminophen-containing product. The excessive intake of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or unknowingly take other acetaminophen-containing products (see Boxed Warning). The risk of acute liver ...
                        	... involve more than one acetaminophen-containing product. The excessive intake of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or unknowingly take other acetaminophen-containing products (see Boxed Warning). The risk of acute liver ...
									Lithium Key Points Introduction in General Practice
									
... drug concentrations reducing therapeutic response or ...
                        	... drug concentrations reducing therapeutic response or ...
									GPAT 2010 Question Paper
									
... Q.21 Which one of the followings is used as a mood stabilizer for bipolar disorder and also in certain epileptic convulsions? (A) Phenytoin (B) Lithium (C) Sodium valproate (D) Fluoxetine Ans. Q.22 An isosteric replacement for carboxylic acid group is (A) pyrrole (B) isoxazole (C) phenol (D) tetrazo ...
                        	... Q.21 Which one of the followings is used as a mood stabilizer for bipolar disorder and also in certain epileptic convulsions? (A) Phenytoin (B) Lithium (C) Sodium valproate (D) Fluoxetine Ans. Q.22 An isosteric replacement for carboxylic acid group is (A) pyrrole (B) isoxazole (C) phenol (D) tetrazo ...
									Mechanism-based Inhibition: Deriving KI and kinact
									
... where PI(t) and P0(t) denote the concentration of product at time t in the presence of an inhibitor (at concentration I), respectively, in the absence of any inhibitor. Based on the control, the IC50 value is then defined as the inhibitor concentration at which the product concentration is half the ...
                        	... where PI(t) and P0(t) denote the concentration of product at time t in the presence of an inhibitor (at concentration I), respectively, in the absence of any inhibitor. Based on the control, the IC50 value is then defined as the inhibitor concentration at which the product concentration is half the ...
									An Update on Artemisinin- A Multifaceted Drug
									
... Discovery of artemisinin and establishment of its antimalarial activity by Chinese scientists represents one of the great discoveries in medicine in the latter half of the 20th century (1960s). During 20th century middle World Health Organisation (WHO) made successful attempts to eradicate malaria a ...
                        	... Discovery of artemisinin and establishment of its antimalarial activity by Chinese scientists represents one of the great discoveries in medicine in the latter half of the 20th century (1960s). During 20th century middle World Health Organisation (WHO) made successful attempts to eradicate malaria a ...
									amyotrophic lateral sclerosis (als) – opportunity analysis and
									
... Amyotrophic Lateral Sclerosis (ALS) – Opportunity Analysis and Forecasts to 2018 © GlobalData. This report is a licensed product and is not to be copied, reproduced, shared or resold in any form. ...
                        	... Amyotrophic Lateral Sclerosis (ALS) – Opportunity Analysis and Forecasts to 2018 © GlobalData. This report is a licensed product and is not to be copied, reproduced, shared or resold in any form. ...
									CONTROLLED SUBSTANCES
									
... an identification card issued by a governmental agency, provided the identification card meets the requirements of this rule. (2) As used in part 5 of these rules: (a) "Medical institution" means an inpatient health facility which is licensed or approved by the state and which directly or indirectly ...
                        	... an identification card issued by a governmental agency, provided the identification card meets the requirements of this rule. (2) As used in part 5 of these rules: (a) "Medical institution" means an inpatient health facility which is licensed or approved by the state and which directly or indirectly ...
									FDA Approved Labeling 12.19.08 3pm NovaDel Pharma Inc.
									
... A variety of abnormal thinking and behavioral changes have been reported to occur in association with the use of sedative-hypnotics. Some of these changes may be characterized by decreased inhibition (e.g., aggressiveness and extroversion that seemed out of character), similar to effects produced by ...
                        	... A variety of abnormal thinking and behavioral changes have been reported to occur in association with the use of sedative-hypnotics. Some of these changes may be characterized by decreased inhibition (e.g., aggressiveness and extroversion that seemed out of character), similar to effects produced by ...
									Marijuana: The Facts - Drug Policy Alliance
									
... have increased. xxviii Emerging evidence indicates that patients who have tried marijuana may show significant improvements in symptoms and clinical outcomes (such as lower mortality ratesxxix and better cognitive functioningxxx ) compared with those who have not. In fact, some of the unique chemica ...
                        	... have increased. xxviii Emerging evidence indicates that patients who have tried marijuana may show significant improvements in symptoms and clinical outcomes (such as lower mortality ratesxxix and better cognitive functioningxxx ) compared with those who have not. In fact, some of the unique chemica ...
									A Position Paper - American College of Physicians
									
... placed marijuana in the Schedule I category along with other substances deemed to have no medicinal value and high potential for abuse. Still, the overwhelming number of anecdotal reports on the therapeutic properties of marijuana sparks interest from scientists, health care providers, and patients. ...
                        	... placed marijuana in the Schedule I category along with other substances deemed to have no medicinal value and high potential for abuse. Still, the overwhelming number of anecdotal reports on the therapeutic properties of marijuana sparks interest from scientists, health care providers, and patients. ...
									Does Oral Trenbolone Really Have the Best Steroid
									
... Oral Trenbolone PCT The drugs you will take during PCT include aromatase inhibitors and Selective Estrogen Receptor Modulators (SERM). Aromatase inhibitors stop androgens from binding with estrogen receptors and SERMs are supposed to prevent their effects. However, with oral Trenbolone, users are sp ...
                        	... Oral Trenbolone PCT The drugs you will take during PCT include aromatase inhibitors and Selective Estrogen Receptor Modulators (SERM). Aromatase inhibitors stop androgens from binding with estrogen receptors and SERMs are supposed to prevent their effects. However, with oral Trenbolone, users are sp ...
									Fentanyl - CannAmm
									
... Fentanyl is used to manage severe pain and post-surgery pain in medicine. Fentanyl is 100 times more powerful than morphine at the equivalent dose by weight. Fentanyl is a synthetic opiate, classified as a pain killer that is available in prescription form Actiq®, Duragesic®, Fentora®, Sublimaze® an ...
                        	... Fentanyl is used to manage severe pain and post-surgery pain in medicine. Fentanyl is 100 times more powerful than morphine at the equivalent dose by weight. Fentanyl is a synthetic opiate, classified as a pain killer that is available in prescription form Actiq®, Duragesic®, Fentora®, Sublimaze® an ...
									Zebrafish as tools for drug discovery
									
... compounds discovered via diverse zebrafish screens in corresponding rodent disease models. Eight of the ten compounds produced the desired effect in rodents, with little or no optimization via medicinal chemistry or formulation25–31. Although the sample size is small, these experiences have led us t ...
                        	... compounds discovered via diverse zebrafish screens in corresponding rodent disease models. Eight of the ten compounds produced the desired effect in rodents, with little or no optimization via medicinal chemistry or formulation25–31. Although the sample size is small, these experiences have led us t ...
									Problems of anabolic steroids in sport.
									
... showed a high incidence of side effects including headache, hypertension, urinary trouble, and raised levels of serum cholesterol and alanine transaminase. Also cholesterol levels were elevated but this may be a result of the diet rather than the drug effect. Wynn (1975) has reported that orally act ...
                        	... showed a high incidence of side effects including headache, hypertension, urinary trouble, and raised levels of serum cholesterol and alanine transaminase. Also cholesterol levels were elevated but this may be a result of the diet rather than the drug effect. Wynn (1975) has reported that orally act ...
									DRUG NAME - BC Cancer Agency
									
... Use with caution in: patients using other neurotoxic drugs3 and patients using other ototoxic drugs including aminoglycosides, carboplatin, cisplatin and furosemide.3 Carcinogenicity: secondary malignancies have developed in patients receiving vincristine with other known ...
                        	... Use with caution in: patients using other neurotoxic drugs3 and patients using other ototoxic drugs including aminoglycosides, carboplatin, cisplatin and furosemide.3 Carcinogenicity: secondary malignancies have developed in patients receiving vincristine with other known ...
									Stability considerations in liquid dosage forms extemporaneously
									
... cases where medicines were modified, spillage, and thus potential loss of dosage, was observed. The administration of the crushed medicines then poses a further concern, as in the majority of cases, the crushed medication was mixed in a small medication cup with a soft medium such as jam, custard or ...
                        	... cases where medicines were modified, spillage, and thus potential loss of dosage, was observed. The administration of the crushed medicines then poses a further concern, as in the majority of cases, the crushed medication was mixed in a small medication cup with a soft medium such as jam, custard or ...
 
									 
									 
									 
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