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Stephen F. Davis
Stephen F. Davis

... • Neurotransmitters enable the signal from one neuron to be relayed to other neurons across the synapse, a small gap that separates neurons. • A myelin sheath covers the axons of some neurons to increase the speed of transmission of the neural signal. ...
Electrophysiological evidence that noradrenergic neurons of the rat
Electrophysiological evidence that noradrenergic neurons of the rat

... inclination were placed on the brain surface 4 mm posterior to the lambda, 0-0.4 mm lateral to the midline. DRN neurons were found 5800-6000 µm below brain surface. Neurons were identified as serotonergic if they met the criteria defined previously by McGinty and Harper (1976), Trulson and Jacobs (1 ...
Werkstuk Biologie The Tongue  <strong style="line
Werkstuk Biologie The Tongue
Function of Conserved Tryptophans in the Aspergillus niger
Function of Conserved Tryptophans in the Aspergillus niger

... culture were greatly reduced when compared with that of the wild-type SBD: less than 1 mg for W615K and approximately 5 mg for W590K compared to more than 200 mg for the wild-type SBD. We obtained a better yield for W563K, 30-50 mg. The W615K and W590K proteins and recombinant wild-type SBD were pur ...
B) Contain an alcohol - LSU School of Medicine
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... Remove residues sequentially such that the last one added during synthesis is the first one removed during degradation. Defects in the enzymes lead to a large spectrum of diseases called lipid storage diseases or sphingolipidoses. Have accumulation of undigested glycosphingolipids within cells (Fig. ...
Sequencing the connectome. - Cold Spring Harbor Laboratory
Sequencing the connectome. - Cold Spring Harbor Laboratory

... Mammalian circuits contain orders of magnitude more neurons than C. elegans. Although neuromodulation is important in mammalian circuits, the need to multiplex function may not be as severe as in C. elegans, which may render the relationship between circuitry and function more transparent. In mammal ...
Neural Conduction - U
Neural Conduction - U

... • thus, any time that there is an accumulation of a particular class of ions in one area, the probability is increased that random motion will move ions out of this area (because there are more ions available to leave) and the probability is decreased that random motion will move more ions into the ...
Self Assessment Chapter 14 - CM
Self Assessment Chapter 14 - CM

... • Sympathetic neurotransmitters (continued): • Acetylcholine (ACh) – neurotransmitter used in excitatory synapses between sympathetic preganglionic axons and postganglionic neurons; postganglionic axons then transmit action potentials to target cell • At synapse with their target cells, postganglion ...
VIEW PDF - Glaucoma Today
VIEW PDF - Glaucoma Today

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Chapter 2
Chapter 2

... • Neurotransmitters enable the signal from one neuron to be relayed to other neurons across the synapse, a small gap that separates neurons. • A myelin sheath covers the axons of some neurons to increase the speed of transmission of the neural signal. ...
a r t I C l e S
a r t I C l e S

... apoptotic corpse removal in developing mouse dorsal root ganglia (DRG). Confocal and electron microscopic analysis revealed that glial precursors, rather than macrophages, were responsible for clearing most of the dead DRG neurons. Moreover, we identified Jedi-1, an engulfment receptor, and MEGF10, ...
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... Shafit-Zagardo B, Kress Y, Zhao ML, Lee SC. A novel microtubule-associated protein-2 expressed in oligodendrocytes in multiple sclerosis lesions. J Neurochem. ...
GABAergic Influence on Taste Information in the Central Gustatory
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... Gamma-aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the brain. It often plays a regulatory role, used in synapses with nearby neurons to provide control through inhibition. There are several well-studied types of GABA receptors: GABAA, GABAB, and GABAC receptors. GABAA and ...
Renal Fanconi syndrome: taking a proximal look at the nephron
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... R F S : T H E I N H E R I TA N C E There are several genetic forms of RFS, the majority of which are associated with multisystem disorders (Table 1). In general, the disease mechanism for these disorders can be categorized as either (i) accumulation of a toxic metabolite (e.g. cystinosis, tyrosinaem ...
complete_ch14_1 - Fullfrontalanatomy.com
complete_ch14_1 - Fullfrontalanatomy.com

... Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings ...
The 18th European Conference on Artificial - CEUR
The 18th European Conference on Artificial - CEUR

... CAs, and accumulated fatigue causes the action CA to stop. Simple movements do not require any facts, but actions are often predicated on facts that are set by the environment. For example, an environmentally sensitive command is Turn toward the pyramid. In this case, the vision system ignites a fac ...
Missed connections: photoreceptor axon seeks target neuron for
Missed connections: photoreceptor axon seeks target neuron for

... Each of the 800 ommatidia of the Drosophila compound eye contains 8 photoreceptor cells, which project their axons directly into the brain in a retinotopic manner. The outer photoreceptors R1–R6 all express the same Rhodopsin and project into the first optic neuropil, the lamina, which mediates imag ...
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High-performance genetically targetable optical neural silencing by
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... To directly assess Arch in vivo, we injected lentivirus encoding for Arch into mouse cortex and recorded neural responses ~1 month later. Arch expressed well (Fig. 3Bi) and appeared well localized to the plasma membrane, labeling cell bodies, processes, and dendritic spines (Fig. 3Bii). We recorded ...
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Full version (PDF file)
Full version (PDF file)

... name based on the structural similarity to calbindin D28k and the site of first detection (retina) (Rogers 1987). Calretinin in general shares many features with calbindin D28k and belongs to calbindin D28k subfamily of CaBP. The gene for CR is located on chromosome 16 (Parmentier et al. 1991). CR i ...
Metabolic Disorders Referral Guidelines
Metabolic Disorders Referral Guidelines

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a spiking stretch receptor with central cell bodies in the uropod
a spiking stretch receptor with central cell bodies in the uropod

... response characteristics (Fig. 6). These afferent units can be recorded after all nerves other than those innervating the elastic strand have been cut, but a more intact preparation was usually used, since no difference could be detected. There is no 'off' response on relaxation of the receptor. (2) ...
A comparative study of the mammalian amygdala
A comparative study of the mammalian amygdala

... described above, but they differ in some peculiar features. The proximal dendritic trunks can be very short, in the form of dichotomically divided broad stems. From these stalks bifurcate the beaded secondary branches. Each ramification produces thinner and more varicose dendritic branches. The spin ...
Lecture 1 st week
Lecture 1 st week

... • more than 99 per cent of all sensory information is discarded by the brain as irrelevant and unimportant (clothing, seat pressure) • important sensory information excites the mind this channeling and processing of information is called the integrative function of the nervous system • some synapses ...
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Clinical neurochemistry



Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.
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