Nerves
... • The cerebral cortex receives input from sensory organs and somatosensory receptors • Specific types of sensory input enter the primary sensory areas of the brain lobes • Adjacent areas process features in the sensory input and integrate information from different sensory areas • In the somatosenso ...
... • The cerebral cortex receives input from sensory organs and somatosensory receptors • Specific types of sensory input enter the primary sensory areas of the brain lobes • Adjacent areas process features in the sensory input and integrate information from different sensory areas • In the somatosenso ...
The neurophysiological correlates of motor tics following focal
... motor tics confined to a single or a few muscles. The temporal and structural properties of the tics were identified using electromyogram and frame-by-frame analysis of multi-camera video recordings. During experimental sessions the tics would wax and wane, but their size and shape remained highly s ...
... motor tics confined to a single or a few muscles. The temporal and structural properties of the tics were identified using electromyogram and frame-by-frame analysis of multi-camera video recordings. During experimental sessions the tics would wax and wane, but their size and shape remained highly s ...
100 The Molecular and Structural Basis of Amblyopia
... one visual hemifield viewed by the ipsilateral eye (blue region, monocular visual field) and by both eyes (green region, binocular visual field) is represented in V1. The eye ipsilateral to the hemifield (blue) projects to the contralateral hemisphere whereas the contralateral eye viewing the same s ...
... one visual hemifield viewed by the ipsilateral eye (blue region, monocular visual field) and by both eyes (green region, binocular visual field) is represented in V1. The eye ipsilateral to the hemifield (blue) projects to the contralateral hemisphere whereas the contralateral eye viewing the same s ...
Brain Organization and Handedness
... Demonstration: Try moving your right hand in a circular motion, as if polishing a table. Now start your right foot doing the same motion synchronized with the hand. Now reverse the foot motion (but not the hand). Tough, huh? But easier if you try moving the left foot opposite to the right hand. The ...
... Demonstration: Try moving your right hand in a circular motion, as if polishing a table. Now start your right foot doing the same motion synchronized with the hand. Now reverse the foot motion (but not the hand). Tough, huh? But easier if you try moving the left foot opposite to the right hand. The ...
Poly(A) Binding Protein Nuclear 1 regulates the
... Pabpn1 knock down interferes with homeostatic plasticity Given the above regulation of both Camk2a and Gria2, we next determined whether Pabpn1 and polyadenylation play a role in homeostatic plasticity. We elicited homeostatic plasticity using a 24 hours treatment of bicuculline a gammaaminobutyric ...
... Pabpn1 knock down interferes with homeostatic plasticity Given the above regulation of both Camk2a and Gria2, we next determined whether Pabpn1 and polyadenylation play a role in homeostatic plasticity. We elicited homeostatic plasticity using a 24 hours treatment of bicuculline a gammaaminobutyric ...
Reading - Chapter 15 and the Appendix to Chapter 15
... understood in terms of the changes in quaternary structure that accompany the conversion of deoxy Hb to oxy Hb. o The shift from the deoxy to oxy conformation arises from the fact that in deoxy Hb the iron lies out of the plane of the heme ring, but when O2 binding occurs, the iron moves into the pl ...
... understood in terms of the changes in quaternary structure that accompany the conversion of deoxy Hb to oxy Hb. o The shift from the deoxy to oxy conformation arises from the fact that in deoxy Hb the iron lies out of the plane of the heme ring, but when O2 binding occurs, the iron moves into the pl ...
08_NervousSystem
... The Central Nervous System Key Note The sensory and motor nuclei (gray matter) of the spinal cord surround the central canal. Sensory nuclei are dorsal, motor nuclei are ventral. A thick layer of white matter consisting of ascending and descending axons covers the gray matter. These axons are organ ...
... The Central Nervous System Key Note The sensory and motor nuclei (gray matter) of the spinal cord surround the central canal. Sensory nuclei are dorsal, motor nuclei are ventral. A thick layer of white matter consisting of ascending and descending axons covers the gray matter. These axons are organ ...
Nervous
... included: caudate nucleus, putamen and globus pallidus. These are parts of the extrapyramidal UMN system. Function: control of muscle tone, voluntary movements and proprioception Damage: contralateral weakness, UMN signs (in humans: Parkinsonism and Huntington’s disease/chorea) Paralysis: Here: Loss ...
... included: caudate nucleus, putamen and globus pallidus. These are parts of the extrapyramidal UMN system. Function: control of muscle tone, voluntary movements and proprioception Damage: contralateral weakness, UMN signs (in humans: Parkinsonism and Huntington’s disease/chorea) Paralysis: Here: Loss ...
Stimulus-Specific Adaptation in Auditory Cortex Is an NMDA
... that an additional mechanism (and a different model) is required to explain all its properties, which have been revealed by many variations of the oddball paradigm. • Secondly, MMN is produced when a novel event violates a stored neural representation of regularity inherent in the recent sensory env ...
... that an additional mechanism (and a different model) is required to explain all its properties, which have been revealed by many variations of the oddball paradigm. • Secondly, MMN is produced when a novel event violates a stored neural representation of regularity inherent in the recent sensory env ...
pdf file - 366KB
... and search the Display File list to access the catalytic site. Although some target enzyme active sites are not available from PDB files, it is possible to estimate how strongly a molecule will bind to a catalytic site by selecting the ligand’s surface contacts favorably interacting with specific fu ...
... and search the Display File list to access the catalytic site. Although some target enzyme active sites are not available from PDB files, it is possible to estimate how strongly a molecule will bind to a catalytic site by selecting the ligand’s surface contacts favorably interacting with specific fu ...
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... has led to assumptions that amyloid formation is essential for the formation of PrPs". However, PrPs" can be formed in the absence of amyloid, and the presence of amyloid plaques is not obligâtory for prion diseases.3 ...
... has led to assumptions that amyloid formation is essential for the formation of PrPs". However, PrPs" can be formed in the absence of amyloid, and the presence of amyloid plaques is not obligâtory for prion diseases.3 ...
The importance of Wnt signalling for neurodegeneration in
... over the last decade [6]. Indeed, in the case of AD (Alzheimer’s disease), evidence is sufficiently strong for a unifying hypothesis for the aetiology of this disease to have been made, centred around dysregulated Wnt cascades [6]. Importantly, both canonical and non-canonical Wnt pathways have been ...
... over the last decade [6]. Indeed, in the case of AD (Alzheimer’s disease), evidence is sufficiently strong for a unifying hypothesis for the aetiology of this disease to have been made, centred around dysregulated Wnt cascades [6]. Importantly, both canonical and non-canonical Wnt pathways have been ...
Marginal chimera state at cross-frequency locking of pulse
... Studies of the dynamics of globally coupled populations of oscillators, pioneered more than 40 years ago by Winfree and Kuramoto [1], are the focus of current research due to numerous applications in diverse fields from physics to neuroscience, but also due to striking effects such as synchronizatio ...
... Studies of the dynamics of globally coupled populations of oscillators, pioneered more than 40 years ago by Winfree and Kuramoto [1], are the focus of current research due to numerous applications in diverse fields from physics to neuroscience, but also due to striking effects such as synchronizatio ...
Autonomic NS
... • A single sympathetic preganglionic fiber has many axon collaterals and may synapse with 20 or more postganglionic neurons. • The postganglionic axons typically terminate in several visceral effectors and therefore the effects of sympathetic stimulation are more widespread than the effects of paras ...
... • A single sympathetic preganglionic fiber has many axon collaterals and may synapse with 20 or more postganglionic neurons. • The postganglionic axons typically terminate in several visceral effectors and therefore the effects of sympathetic stimulation are more widespread than the effects of paras ...
Nothing can be coincidence: synaptic inhibition and plasticity in the
... circuits with intrinsically active neurons have rules for information transfer and storage that distinguish them from other brain regions. Introduction Neurons and synapses throughout the vertebrate brain share many common properties, which have given rise to the useful generalizations taught in int ...
... circuits with intrinsically active neurons have rules for information transfer and storage that distinguish them from other brain regions. Introduction Neurons and synapses throughout the vertebrate brain share many common properties, which have given rise to the useful generalizations taught in int ...
Cerebellum: The Brain for an Implicit Self
... The primary rationale for my writing this book is that I have been involved in research on the cerebellum for half a century and it seemed appropriate to share with younger generations of researchers how thrilling and dramatic this epoch has been, particularly since research on the cerebellum has ad ...
... The primary rationale for my writing this book is that I have been involved in research on the cerebellum for half a century and it seemed appropriate to share with younger generations of researchers how thrilling and dramatic this epoch has been, particularly since research on the cerebellum has ad ...
Figure 15.9
... • A single sympathetic preganglionic fiber has many axon collaterals and may synapse with 20 or more postganglionic neurons. • The postganglionic axons typically terminate in several visceral effectors and therefore the effects of sympathetic stimulation are more widespread than the effects of paras ...
... • A single sympathetic preganglionic fiber has many axon collaterals and may synapse with 20 or more postganglionic neurons. • The postganglionic axons typically terminate in several visceral effectors and therefore the effects of sympathetic stimulation are more widespread than the effects of paras ...
RESOURCE - Synthetic Neurobiology Group
... Cre mouse lines, generated in individual labs and through large-scale efforts8–10, have been established to direct specific gene expression or deletion in a wide range of cell types or populations throughout the nervous system. A challenge in developing optogenetic tools is the need to express high ...
... Cre mouse lines, generated in individual labs and through large-scale efforts8–10, have been established to direct specific gene expression or deletion in a wide range of cell types or populations throughout the nervous system. A challenge in developing optogenetic tools is the need to express high ...
Regulation of Action-Potential Firing in Spiny Neurons of the Rat
... firing in spiny neurons of the rat neostriatum in vivo. J. Neurophysiol. 79: 2358–2364, 1998. Both silent and spontaneously firing spiny projection neurons have been described in the neostriatum, but the reason for their differences in firing activity are unknown. We compared properties of spontaneo ...
... firing in spiny neurons of the rat neostriatum in vivo. J. Neurophysiol. 79: 2358–2364, 1998. Both silent and spontaneously firing spiny projection neurons have been described in the neostriatum, but the reason for their differences in firing activity are unknown. We compared properties of spontaneo ...
Regulation of Action-Potential Firing in Spiny Neurons of the Rat
... firing in spiny neurons of the rat neostriatum in vivo. J. Neurophysiol. 79: 2358–2364, 1998. Both silent and spontaneously firing spiny projection neurons have been described in the neostriatum, but the reason for their differences in firing activity are unknown. We compared properties of spontaneo ...
... firing in spiny neurons of the rat neostriatum in vivo. J. Neurophysiol. 79: 2358–2364, 1998. Both silent and spontaneously firing spiny projection neurons have been described in the neostriatum, but the reason for their differences in firing activity are unknown. We compared properties of spontaneo ...
Binding Site Differences Revealed by Crystal
... which is in broad agreement with the binding assays described above. Superposition of the PfACBP crystal structure onto the bACBP-palmitoyl-CoA NMR structure shows that the C16 atom of palmitoyl-CoA in the bovine structure superimÊ 2) poses with the well-ordered (B-factor 46.5 A terminal atom of t ...
... which is in broad agreement with the binding assays described above. Superposition of the PfACBP crystal structure onto the bACBP-palmitoyl-CoA NMR structure shows that the C16 atom of palmitoyl-CoA in the bovine structure superimÊ 2) poses with the well-ordered (B-factor 46.5 A terminal atom of t ...
The Red Nucleus: Past, Present, and Future
... was consistent with the more stereotyped behavior of these vertebrates. The greater repertoire of movements in mammals involves a more complex circuitry, including a higher complexity level of the RN and an increased development of the pyramidal tract. What little is known about the human RNp has be ...
... was consistent with the more stereotyped behavior of these vertebrates. The greater repertoire of movements in mammals involves a more complex circuitry, including a higher complexity level of the RN and an increased development of the pyramidal tract. What little is known about the human RNp has be ...
ChennWalshCeCortexJu..
... populations indicated that despite the massive expansion of cortical surface area, transgenic precursors appeared to differentiate into young neurons in an approximately normal spatial pattern (Chenn and Walsh, 2002). Taken together, the expression studies suggested that over-activating β-catenin di ...
... populations indicated that despite the massive expansion of cortical surface area, transgenic precursors appeared to differentiate into young neurons in an approximately normal spatial pattern (Chenn and Walsh, 2002). Taken together, the expression studies suggested that over-activating β-catenin di ...
Clinical neurochemistry
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.