Mechanical Response Properties of A and C Primary Afferent
... of meningeal sensory fibers (Wolff 1963). Migraine headache, although not accompanied by any detectable pathology, shares certain clinical features with headaches of intracranial origin, and has also been postulated to result from activation of the meningeal sensory innervation (reviewed in Strassma ...
... of meningeal sensory fibers (Wolff 1963). Migraine headache, although not accompanied by any detectable pathology, shares certain clinical features with headaches of intracranial origin, and has also been postulated to result from activation of the meningeal sensory innervation (reviewed in Strassma ...
Memory, Learning, and Synaptic Plasticity
... time, suppose that input patterns are represented by the simultaneous firing of 10 out of 100 input neurons; choosing 10 active input fibers out of 100 provides ~1013 different events. Even if the input fibers encode a different event each millisecond, the system can run for more than 300 years with ...
... time, suppose that input patterns are represented by the simultaneous firing of 10 out of 100 input neurons; choosing 10 active input fibers out of 100 provides ~1013 different events. Even if the input fibers encode a different event each millisecond, the system can run for more than 300 years with ...
Neural and Computational Mechanisms of Action Processing
... the knowledge in terms of fundamental neural mechanisms that provide constraints for underlying computations remains rather limited. This fact stands in contrast with a wide variety of speculative theories about how action recognition might work, and how it might interact with other cognitive brain ...
... the knowledge in terms of fundamental neural mechanisms that provide constraints for underlying computations remains rather limited. This fact stands in contrast with a wide variety of speculative theories about how action recognition might work, and how it might interact with other cognitive brain ...
Combined fluorescence and electrochemical investigation on the
... NMR studies by Hamilton’s group reveal that among the seven fatty acid binding sites, sites 2, 4 and 5 are high affinity sites, while sites 1, 3, 6 and 7 exhibit low affinity for fatty acids (Simard et al., 2006). The unique ligand binding properties of HSA also include binding of a large number of exog ...
... NMR studies by Hamilton’s group reveal that among the seven fatty acid binding sites, sites 2, 4 and 5 are high affinity sites, while sites 1, 3, 6 and 7 exhibit low affinity for fatty acids (Simard et al., 2006). The unique ligand binding properties of HSA also include binding of a large number of exog ...
Diverse functions of perineuronal nets
... These results indicate that tenascin-R is essential for ECM proteoglycans to form the lattice-like structure (Weber et al. 1999, Haunso et al. 2000). It appears that precise timing of the CS proteoglycans expression seems to be specific for both cortical areas and particular cortical layers. For exa ...
... These results indicate that tenascin-R is essential for ECM proteoglycans to form the lattice-like structure (Weber et al. 1999, Haunso et al. 2000). It appears that precise timing of the CS proteoglycans expression seems to be specific for both cortical areas and particular cortical layers. For exa ...
Critical Periods:
... Progesterone has biphasic effects on sex behavior in the female rat: • progesterone interacts with PRs to stimulate the display of lordosis (as well as the display of proceptive behaviors) • prolonged exposure to progesterone can inhibit sex behavior Mechanism of inhibitory effects: • progesterone c ...
... Progesterone has biphasic effects on sex behavior in the female rat: • progesterone interacts with PRs to stimulate the display of lordosis (as well as the display of proceptive behaviors) • prolonged exposure to progesterone can inhibit sex behavior Mechanism of inhibitory effects: • progesterone c ...
Poster
... interactions with a number of nonpolar residues contribute to hydrolase inhibitor binding. Inhibitor design targeted the hydrolase active site; however, a known inhibitor of the phosphatase active site was linked to putative hydrolase inhibitors to create bi-substrate inhibitors, which are expected ...
... interactions with a number of nonpolar residues contribute to hydrolase inhibitor binding. Inhibitor design targeted the hydrolase active site; however, a known inhibitor of the phosphatase active site was linked to putative hydrolase inhibitors to create bi-substrate inhibitors, which are expected ...
Binding and Cytotoxic Effects of Clostdium botulinum Type A, C1
... intraperitoneal injection, 10 LD5o ml-l (250 pg ml-l) of toxin was used; 0.5 mI of the mixtures was injected and the mice were observed for 6 d. For intravenous injection, 2 x lo5 LDS0ml-l (5 pg ml-l) was used, and 0.1 ml of the mixtures was injected. The average time to death and the percentage of ...
... intraperitoneal injection, 10 LD5o ml-l (250 pg ml-l) of toxin was used; 0.5 mI of the mixtures was injected and the mice were observed for 6 d. For intravenous injection, 2 x lo5 LDS0ml-l (5 pg ml-l) was used, and 0.1 ml of the mixtures was injected. The average time to death and the percentage of ...
Cellular and Molecular Mechanisms of Learning and Memory
... development of a cellular analog of Pavlovian conditioning, a form of associative learning, as well as habituation and sensitization, nonassociative forms of learning. In particular, studies in Aplysia have revealed some of the important cellular and molecular mechanisms underlying synaptic plastici ...
... development of a cellular analog of Pavlovian conditioning, a form of associative learning, as well as habituation and sensitization, nonassociative forms of learning. In particular, studies in Aplysia have revealed some of the important cellular and molecular mechanisms underlying synaptic plastici ...
spinal cord and reflexes - Sinoe Medical Association
... sciatic nerve the body's largest nerve, consisting of two major branches, the tibial and common peroneal. Together they innervate most all of leg including the flexors of the knee, part of adductor magnus, muscles for plantar flexion, dorsiflexion, and other mov ...
... sciatic nerve the body's largest nerve, consisting of two major branches, the tibial and common peroneal. Together they innervate most all of leg including the flexors of the knee, part of adductor magnus, muscles for plantar flexion, dorsiflexion, and other mov ...
Neural coding of basic reward terms of animal
... of rewards for behavioural reactions and decisions can be assessed from the multiplicative product of magnitude and probability of the future reward (expected reward value). In addition, the delay to the future reward reduces the reward value hyperbolically [8]. However, the simple products of magni ...
... of rewards for behavioural reactions and decisions can be assessed from the multiplicative product of magnitude and probability of the future reward (expected reward value). In addition, the delay to the future reward reduces the reward value hyperbolically [8]. However, the simple products of magni ...
Slide 7.45b
... The uninjured cell body gets larger in order to synthesize proteins needed for ...
... The uninjured cell body gets larger in order to synthesize proteins needed for ...
Fixing Functionalism
... In the case of consciousness, there are two motivations for achieving parsimony. First, as in all theoretical endeavors, the simpler theory is more likely to generalize to novel data. A highly disjunctive theory that is ‘jury-rigged’ to fit a particular set of observations will have difficulties whe ...
... In the case of consciousness, there are two motivations for achieving parsimony. First, as in all theoretical endeavors, the simpler theory is more likely to generalize to novel data. A highly disjunctive theory that is ‘jury-rigged’ to fit a particular set of observations will have difficulties whe ...
Differential roles of delay-period neural activity in the monkey
... period. Ten of those 21 whole-delay cells were horizontal-preferred and the other 11 were vertical-preferred. During the choice period, 32 (20.4%) differential neurons were observed. A large proportion of differential units showed differential activity in more than one period (Table S1 and SI Materi ...
... period. Ten of those 21 whole-delay cells were horizontal-preferred and the other 11 were vertical-preferred. During the choice period, 32 (20.4%) differential neurons were observed. A large proportion of differential units showed differential activity in more than one period (Table S1 and SI Materi ...
The role of the hypothalamic dorsomedial nucleus in the central
... 5.2.2. PrRP-containing nerve fibers and terminals in the DMH PrRP immunolabeling was detected in different parts of the hypothalamus. PrRP-ir cell bodies appeared exclusively in the most caudal part of the DMH, while PrRP-ir fibers were present in the dorsal and ventral subdivisions of the DMH, as ...
... 5.2.2. PrRP-containing nerve fibers and terminals in the DMH PrRP immunolabeling was detected in different parts of the hypothalamus. PrRP-ir cell bodies appeared exclusively in the most caudal part of the DMH, while PrRP-ir fibers were present in the dorsal and ventral subdivisions of the DMH, as ...
Sympathetic Chain
... • Cervical Part Ganglia Superior Cervical ganglia Middle Cervical Ganglia Inferior Cervical ganglia Sometimes Inferior cervical and first Thoracic fuse to form a Cervico-Thoracic or Stellate Ganglia ...
... • Cervical Part Ganglia Superior Cervical ganglia Middle Cervical Ganglia Inferior Cervical ganglia Sometimes Inferior cervical and first Thoracic fuse to form a Cervico-Thoracic or Stellate Ganglia ...
Temporal and spatial alterations in GPi neuronal encoding might
... (ii) rigidity and (iii) akinesia (Agid, 1991). The term akinesia literally means ‘no movement’ and describes the impairment of voluntary motor performance. Akinesia encompasses a rich symptomatology ranging from true akinesia to, more often, several degrees of bradykinesia, e.g. the delay and slowin ...
... (ii) rigidity and (iii) akinesia (Agid, 1991). The term akinesia literally means ‘no movement’ and describes the impairment of voluntary motor performance. Akinesia encompasses a rich symptomatology ranging from true akinesia to, more often, several degrees of bradykinesia, e.g. the delay and slowin ...
Representing Spatial Information for Limb - Research
... terms, depending on the model, q, was expressed in Cartesian, spherical, spherangular, or angular coordinates, depending on the coordinate system chosen to describe limb position. All targets (n = 24) and repetitions (n = 5) were used in the regressions for each cell. Statistical significance of the ...
... terms, depending on the model, q, was expressed in Cartesian, spherical, spherangular, or angular coordinates, depending on the coordinate system chosen to describe limb position. All targets (n = 24) and repetitions (n = 5) were used in the regressions for each cell. Statistical significance of the ...
Molecular Imprinting of Maltose Binding Protein
... spectroscopy to verify that no protein was removed from the polymer during mica separation. The thickness of all imprinted and nonimprinted films on the glass slides was about 100 μm as measured by profilometer. MBP-Cy3 was extracted from the polymer film by digestion with proteinase K (400 μg mL1 in ...
... spectroscopy to verify that no protein was removed from the polymer during mica separation. The thickness of all imprinted and nonimprinted films on the glass slides was about 100 μm as measured by profilometer. MBP-Cy3 was extracted from the polymer film by digestion with proteinase K (400 μg mL1 in ...
motor pathways i-iii
... A. An UMN disorder will deprive the LMNs of the control normally exerted by the UMNs. The LMNs and their connections to skeletal muscles remain intact, but muscle strength, voluntary activity, tone and reflexes are all modified by this loss of control. B. Symptoms and signs of UMN lesions include: 1 ...
... A. An UMN disorder will deprive the LMNs of the control normally exerted by the UMNs. The LMNs and their connections to skeletal muscles remain intact, but muscle strength, voluntary activity, tone and reflexes are all modified by this loss of control. B. Symptoms and signs of UMN lesions include: 1 ...
Motor Cortex Stimulation for Refractory Benign Pain
... potential candidate for MSC, a number of issues must be taken into consideration, as follows: 1. Common neurosurgical considerations for patient selection and risk management, such as assessment of cardiovascular risk, major organ disease, overall health, clotting disorders or use of anticlotting ag ...
... potential candidate for MSC, a number of issues must be taken into consideration, as follows: 1. Common neurosurgical considerations for patient selection and risk management, such as assessment of cardiovascular risk, major organ disease, overall health, clotting disorders or use of anticlotting ag ...
Zebrafish Get Connected: Investigating Neurotransmission Targets
... Gs proteins, and independent of G proteins to activate alternative pathways. Downstream targets include phospholipase D, and protein kinase pathways such as Jun kinase, the mitogen-activated protein kinase/extracellular receptor kinase (MAPK/ERK) pathway, and the mammalian target of rapamycin (MTOR) ...
... Gs proteins, and independent of G proteins to activate alternative pathways. Downstream targets include phospholipase D, and protein kinase pathways such as Jun kinase, the mitogen-activated protein kinase/extracellular receptor kinase (MAPK/ERK) pathway, and the mammalian target of rapamycin (MTOR) ...
Brain-implantable biomimetic electronics as the next era in neural
... forage for food [12]. Major inputs to the hippocampus arise from virtually all other cortical brain regions, and transmit to hippocampus high-level features extracted by each of the sensory systems subserved by these cortical areas. Thus, the hippocampus processes both unimodal and multimodal featur ...
... forage for food [12]. Major inputs to the hippocampus arise from virtually all other cortical brain regions, and transmit to hippocampus high-level features extracted by each of the sensory systems subserved by these cortical areas. Thus, the hippocampus processes both unimodal and multimodal featur ...
A Motion-sensitive Area in Ferret Extrastriate
... Preferred directions of visual stimulus motion were determined utilizing the weighted average method. Each spike time was assigned a vector corresponding to the stimulus direction at this time corrected by the neuron’s response latency. In other words: a response at time t = x ms was related to a st ...
... Preferred directions of visual stimulus motion were determined utilizing the weighted average method. Each spike time was assigned a vector corresponding to the stimulus direction at this time corrected by the neuron’s response latency. In other words: a response at time t = x ms was related to a st ...
Deletion mutant of FGFR4 induces onion
... sequence reads GRAER62A362PEAR. ∆Ext/R4/∆Int was constructed by PCR amplification of a fragment of pcDNA3-∆Ext/R4Tth using forward primer 5′-CTCTGAGGAAGTGGAGCT-3′ and reverse primer 5′-GGATCCTCGGCCGTGGAGCGCCT-3′. The reverse primer hybridizes to positions 1233-1248 and has a tag with a cut site for ...
... sequence reads GRAER62A362PEAR. ∆Ext/R4/∆Int was constructed by PCR amplification of a fragment of pcDNA3-∆Ext/R4Tth using forward primer 5′-CTCTGAGGAAGTGGAGCT-3′ and reverse primer 5′-GGATCCTCGGCCGTGGAGCGCCT-3′. The reverse primer hybridizes to positions 1233-1248 and has a tag with a cut site for ...
Clinical neurochemistry
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.