
Solution
... a) How many times should a fair coin be tossed so that the probability of getting at least one head is at least 99.9%? How about if the coin is not fair, but lands tails 75% of the time? Solution: First note that P ({At least one head}) = 1 − P ({Only tails}). For a fair coin the probability P ({Onl ...
... a) How many times should a fair coin be tossed so that the probability of getting at least one head is at least 99.9%? How about if the coin is not fair, but lands tails 75% of the time? Solution: First note that P ({At least one head}) = 1 − P ({Only tails}). For a fair coin the probability P ({Onl ...
ranef(diag(nfent)=c(0.1))
... The PK Model • gall bladder compartment with a first order rate kb, which, in turn, periodically emptied drug into the last GI transit compartment at a first order rate of kEhc. For modelling purposes, Fent was logit transformed, to constrain its value between 0 and 1, and to allow typical paramete ...
... The PK Model • gall bladder compartment with a first order rate kb, which, in turn, periodically emptied drug into the last GI transit compartment at a first order rate of kEhc. For modelling purposes, Fent was logit transformed, to constrain its value between 0 and 1, and to allow typical paramete ...
Appendix S5. Sensitivity analysis
... Sensitivity analysis of the DEB model was performed using the variance-based Sobol method (Sobol et al., 2007; Saltelli et al., 2010). It is a global and model independent sensitivity analysis method that is based on variance decomposition (quantifying the amount of variance that each parameter cont ...
... Sensitivity analysis of the DEB model was performed using the variance-based Sobol method (Sobol et al., 2007; Saltelli et al., 2010). It is a global and model independent sensitivity analysis method that is based on variance decomposition (quantifying the amount of variance that each parameter cont ...