Molecular and Cellular aspects of a Sacred Disease `Epilepsy`
... have depolarizing effects while chloride ions have both hyper polarizing and depolarizing effects. This can be correlated in a way that if there is loss of function mutation in neuronal potassium channel lead to hyper excitability of neurons thus causing epilepsy (Hubner and Jentsch, 2002). There is ...
... have depolarizing effects while chloride ions have both hyper polarizing and depolarizing effects. This can be correlated in a way that if there is loss of function mutation in neuronal potassium channel lead to hyper excitability of neurons thus causing epilepsy (Hubner and Jentsch, 2002). There is ...
Brain Gate
... Massachusetts man who has been paralyzed from the neck down since 2001, to control a cursor on a screen and to open and close the hand on a prosthetic limb just by thinking about the relevant actions. The movements were his first since he was stabbed five years ago. The attack severed his spinal cor ...
... Massachusetts man who has been paralyzed from the neck down since 2001, to control a cursor on a screen and to open and close the hand on a prosthetic limb just by thinking about the relevant actions. The movements were his first since he was stabbed five years ago. The attack severed his spinal cor ...
Sample pages 2 PDF
... High-resolution atomic structure determination followed by molecular dynamics modeling has also shed light on the mechanisms that enable voltagedependent ion channels to detect changes in voltage and to open or close, but the different methods have not always yielded the same result [15, 16]. Upon cr ...
... High-resolution atomic structure determination followed by molecular dynamics modeling has also shed light on the mechanisms that enable voltagedependent ion channels to detect changes in voltage and to open or close, but the different methods have not always yielded the same result [15, 16]. Upon cr ...
Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant
... with the proportion of wild-type (YFP-expressing) cells within each spinal cord (Fig. 1G). A robust extension in life-span was also seen in the SOD1G93A/lacZ chimeras. Eleven of the 23, including 5 with ⬍30% contribution from wildtype cells, survived disease-free until they were killed at ⬎10 months ...
... with the proportion of wild-type (YFP-expressing) cells within each spinal cord (Fig. 1G). A robust extension in life-span was also seen in the SOD1G93A/lacZ chimeras. Eleven of the 23, including 5 with ⬍30% contribution from wildtype cells, survived disease-free until they were killed at ⬎10 months ...
Glossary OF terms in Spinal Cord Injury Research
... hours during which treatments can be given to prevent progressive or secondary tissue damage. Other investigators may consider the acute period to extend several weeks, during which there may be Wallerian degeneration of spinal tracts that have been cut off from the cell body. The acute period of sp ...
... hours during which treatments can be given to prevent progressive or secondary tissue damage. Other investigators may consider the acute period to extend several weeks, during which there may be Wallerian degeneration of spinal tracts that have been cut off from the cell body. The acute period of sp ...
Axons, but not cell bodies, are activated by electrical stimulation in
... matter is often used to determine the function of a given cortical area or pathway. However, when it is used to elicit postsynaptic effects, the presynaptic neuronal elements activated by electrical stimulation have never been clearly identified: it could be the excitable dendrites, the cell body, t ...
... matter is often used to determine the function of a given cortical area or pathway. However, when it is used to elicit postsynaptic effects, the presynaptic neuronal elements activated by electrical stimulation have never been clearly identified: it could be the excitable dendrites, the cell body, t ...
Single-Neuron Responses in Humans during Execution and
... Action observation/execution nonmatching neuron: a cell responding during action-observation in one condition and action-execution in a different condition (e.g., a cell responding to smile observation and frown execution). Action observation/execution matching neuron: a cell responding during both ...
... Action observation/execution nonmatching neuron: a cell responding during action-observation in one condition and action-execution in a different condition (e.g., a cell responding to smile observation and frown execution). Action observation/execution matching neuron: a cell responding during both ...
The quantitative single-neuron modeling competition | SpringerLink
... ±2 ms precision. We chose this precision level because it is of the same order than synaptic rise times that can be measured in the soma of cortical pyramidal neurons. Data were obtained from a cortical pyramidal neuron in slices of rat barrel cortex [data courtesy of Alexander Rauch and colleagues, ...
... ±2 ms precision. We chose this precision level because it is of the same order than synaptic rise times that can be measured in the soma of cortical pyramidal neurons. Data were obtained from a cortical pyramidal neuron in slices of rat barrel cortex [data courtesy of Alexander Rauch and colleagues, ...
Sequencing the connectome. - Cold Spring Harbor Laboratory
... Like any method, the sequencing approach is subject to false positives (i.e. inferred connections that do not exist) and false negatives (actual connections that are missed). Although the prevalence of each type of error will depend on the details of the implementation, with the sequencing approach ...
... Like any method, the sequencing approach is subject to false positives (i.e. inferred connections that do not exist) and false negatives (actual connections that are missed). Although the prevalence of each type of error will depend on the details of the implementation, with the sequencing approach ...
Encoding Information in Neuronal Activity
... The firing pattern, and the correlations between simultaneously recorded neurons in two separated recording sites, were examined in a number of different conditions , two of which are illustrated in Figure 4.3. In one of these conditions there is a persistent tone, and in the other there is a short ...
... The firing pattern, and the correlations between simultaneously recorded neurons in two separated recording sites, were examined in a number of different conditions , two of which are illustrated in Figure 4.3. In one of these conditions there is a persistent tone, and in the other there is a short ...
CHAPTER 10: NERVOUS SYSTEM I
... MP of neuron falls to -55mV = Threshold Potential Na+ channels open (rapid depolarization) Action Potential (nerve impulse*) is produced MP of neuron reaches +30mV = Reversal of MP K+ channels open ...
... MP of neuron falls to -55mV = Threshold Potential Na+ channels open (rapid depolarization) Action Potential (nerve impulse*) is produced MP of neuron reaches +30mV = Reversal of MP K+ channels open ...
CHAPTER 10: NERVOUS SYSTEM I
... MP of neuron falls to -55mV = Threshold Potential Na+ channels open (rapid depolarization) Action Potential (nerve impulse*) is produced MP of neuron reaches +30mV = Reversal of MP K+ channels open ...
... MP of neuron falls to -55mV = Threshold Potential Na+ channels open (rapid depolarization) Action Potential (nerve impulse*) is produced MP of neuron reaches +30mV = Reversal of MP K+ channels open ...
Introduction to Data Communication Networks - DSpace
... Anatomy of the Nervous systems Neuron cells are the information-processing units of the brain ...
... Anatomy of the Nervous systems Neuron cells are the information-processing units of the brain ...
Chapter 48
... Neurons communicate with other cells at synapses At electrical synapses, the electrical current flows from one neuron to another through gap junctions At chemical synapses, a chemical neurotransmitter carries information between neurons ...
... Neurons communicate with other cells at synapses At electrical synapses, the electrical current flows from one neuron to another through gap junctions At chemical synapses, a chemical neurotransmitter carries information between neurons ...
Nerve Conduction Studies - Cumbria Partnership NHS Foundation
... between the brain and all the other parts of the body. The brain can send signals, in the form of electrical impulses via the spinal cord to the peripheral nervous system. Peripheral nerves can be 'motor' nerves, which means they are attached to muscles and cause the muscles to clench (contract). Th ...
... between the brain and all the other parts of the body. The brain can send signals, in the form of electrical impulses via the spinal cord to the peripheral nervous system. Peripheral nerves can be 'motor' nerves, which means they are attached to muscles and cause the muscles to clench (contract). Th ...
48 BIOLOGY 1. Overview of Neurons 11/3/2014
... Neurons communicate with other cells at synapses At electrical synapses, the electrical current flows from one neuron to another through gap junctions At chemical synapses, a chemical neurotransmitter carries information between neurons ...
... Neurons communicate with other cells at synapses At electrical synapses, the electrical current flows from one neuron to another through gap junctions At chemical synapses, a chemical neurotransmitter carries information between neurons ...
Remembering or Forgetting: The Lifetime of Memories
... opportunities to form connections with neighboring neurons. And not all neurons are alike. While some neurons send signals to other cells telling them to be active, others can inhibit their neighbors and prevent them from sending out signals. As researchers, we are interested in how the brain functi ...
... opportunities to form connections with neighboring neurons. And not all neurons are alike. While some neurons send signals to other cells telling them to be active, others can inhibit their neighbors and prevent them from sending out signals. As researchers, we are interested in how the brain functi ...
RESOURCE - Synthetic Neurobiology Group
... Xue Han4, Eric E Turner3 & Hongkui Zeng1 Cell type–specific expression of optogenetic molecules allows temporally precise manipulation of targeted neuronal activity. Here we present a toolbox of four knock-in mouse lines engineered for strong, Cre-dependent expression of channelrhodopsins ChR2-tdTom ...
... Xue Han4, Eric E Turner3 & Hongkui Zeng1 Cell type–specific expression of optogenetic molecules allows temporally precise manipulation of targeted neuronal activity. Here we present a toolbox of four knock-in mouse lines engineered for strong, Cre-dependent expression of channelrhodopsins ChR2-tdTom ...
temporal visual event recognition
... detectors”, such as those found in the superior central sulcus in the ventral visual pathway [2]. How the brain creates prediction signals in general relates to the fundamental question of how the brain represents time. Buonomano [4] discussed the two prevalent views of how this may be – “labeled li ...
... detectors”, such as those found in the superior central sulcus in the ventral visual pathway [2]. How the brain creates prediction signals in general relates to the fundamental question of how the brain represents time. Buonomano [4] discussed the two prevalent views of how this may be – “labeled li ...
Cochlear Implant Overview
... Adults and children 12 months of age and older, with severe to profound sensorineural hearing loss, may be candidates for a cochlear implant. Typically candidates will have been fitted with hearing aids but receive minimal benefit. Benefit with hearing aids is determined by standard diagnostic tests ...
... Adults and children 12 months of age and older, with severe to profound sensorineural hearing loss, may be candidates for a cochlear implant. Typically candidates will have been fitted with hearing aids but receive minimal benefit. Benefit with hearing aids is determined by standard diagnostic tests ...
Motion perception: Seeing and deciding
... In the present experiments we studied the behavior of these high-level neurons during performance on our direction discrimination task. We sought to determine whether the activity of these neurons could provide an interesting window onto the formation of the monkey’s decision, which is revealed in t ...
... In the present experiments we studied the behavior of these high-level neurons during performance on our direction discrimination task. We sought to determine whether the activity of these neurons could provide an interesting window onto the formation of the monkey’s decision, which is revealed in t ...
Spontaneous firing patterns of identified spiny neurons in the rat
... the sample of identified neurons. In addition there were 5 neurons which could not be identified due to their extreme state of degeneration, presumably caused by impalement with the microelectrode. Mean firing rate The mean firing rates of 94 unidentified striatal neurons and 34 identified spiny cel ...
... the sample of identified neurons. In addition there were 5 neurons which could not be identified due to their extreme state of degeneration, presumably caused by impalement with the microelectrode. Mean firing rate The mean firing rates of 94 unidentified striatal neurons and 34 identified spiny cel ...
Gaze effects in the cerebral cortex: reference frames for
... appear later. Thus, any activity associated with the precue’s presentation may reflect spatial attention and/or memory, or the spatial location of the visual stimulus. Under these experimental conditions, it appears that neuronal activity in PMd is largely modulated by at least three experimental pa ...
... appear later. Thus, any activity associated with the precue’s presentation may reflect spatial attention and/or memory, or the spatial location of the visual stimulus. Under these experimental conditions, it appears that neuronal activity in PMd is largely modulated by at least three experimental pa ...
A Small World of Neuronal Synchrony
... axes of the 2 eyes were 1st determined by mapping the borders of binocular receptive fields (RFs) from responses to moving single bars and then the optical axes were aligned on the computer screen with adjustable prisms placed in front of 1 eye. The software for visual stimulation was the stimulation ...
... axes of the 2 eyes were 1st determined by mapping the borders of binocular receptive fields (RFs) from responses to moving single bars and then the optical axes were aligned on the computer screen with adjustable prisms placed in front of 1 eye. The software for visual stimulation was the stimulation ...
binding, internalization, and retrograde transport of `251
... no tissue. Background levels, grains per pm2, were constant over each individual grid; these values were used where necessary to correct for background in determining real grain counts. From each grid, one or two grid squares were analyzed. In each square, all of the cellular material was photograph ...
... no tissue. Background levels, grains per pm2, were constant over each individual grid; these values were used where necessary to correct for background in determining real grain counts. From each grid, one or two grid squares were analyzed. In each square, all of the cellular material was photograph ...