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Tayler
Tayler

...  Membrane potential – when a neuron is not stimulated  Threshold – the critical level to which membrane potential must be depolarized in order to initiate an action potential  Polarization of the neuron’s membrane: Sodium is on the outside and potassium is on the inside  Resting potential gives ...
Lectures220Week7Note..
Lectures220Week7Note..

... How the generation of an action potential represents an example of positive feedback. How voltage gated channels generate and keep brief the action potential. The flows of major ions during resting, depolarization, repolarization, and hyperpolarization. How myelination leads to rapid propagation ...
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file

... o An action potential involves the change in the permeability of the neuron’s plasma membrane, allowing the movement of two ions, which results in changes in the polarity (charges) of the neuron. ...
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... 6. The different charge between the outside and the inside of a neuron at rest is called action potential. synaptic potential. resting membrane potential. equilibrium potential. 7. The stage in an action potential that immediately follows depolarization is polarization. repolarization. threshold. th ...
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... If the transmitter opens an anion influx, the resulting hyperpolarization is called an Inhibitory Post Synaptic Potential (IPSP All these potentials are additive. ...
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... Excitable cells communicate with each other by action potential (AP) for long distance and by graded potential for short distance. *Production of both types of potentials depend upon the existence of a resting membrane potential (RMP) and the presence of certain types of ion channel. *The RMP is an ...
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...  not a continuous region to region depolarization  instead, a “jumping” depolarization  myelinated axons transmit an Action Potential differently  the myelin sheath acts as an insulator preventing ion flows in and out of the membrane  neurofibral nodes (node of Ranvier) interrupt the myelin she ...
Chapter 32 The Nervous System, Cells of the Nervous System
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... milliseconds, sodium channels close, potassium channels open D As potassium leaves, restores resting potential D Cell cannot respond for short time — refractory period不反 應期 ...
Nervous System Student Notes File
Nervous System Student Notes File

... neurotransmitters that open Na+ gates triggering depolarization c) _________________________________________________ (IPSP) are caused by neurotransmitters which open K+ or Cl- gates causing hyperpolarization d) A single EPSP is rarely strong enough to trigger an action potential, although and addit ...
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... always rush into the cell by diffusion. • Since K+ ion channels are more concentrated in the ICF when a specific voltage gated K+ channel opens K+ will always rush out of the cell by diffusion • In order to keep the resting membrane potential at –70 mV the cell is constantly hydrolyzing ATP with the ...
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Resting potential



The relatively static membrane potential of quiescent cells is called the resting membrane potential (or resting voltage), as opposed to the specific dynamic electrochemical phenomena called action potential and graded membrane potential.Apart from the latter two, which occur in excitable cells (neurons, muscles, and some secretory cells in glands), membrane voltage in the majority of non-excitable cells can also undergo changes in response to environmental or intracellular stimuli. In principle, there is no difference between resting membrane potential and dynamic voltage changes like action potential from a biophysical point of view: all these phenomena are caused by specific changes in membrane permeabilities for potassium, sodium, calcium, and chloride ions, which in turn result from concerted changes in functional activity of various ion channels, ion transporters, and exchangers. Conventionally, resting membrane potential can be defined as a relatively stable, ground value of transmembrane voltage in animal and plant cells.Any voltage is a difference in electric potential between two points—for example, the separation of positive and negative electric charges on opposite sides of a resistive barrier. The typical resting membrane potential of a cell arises from the separation of potassium ions from intracellular, relatively immobile anions across the membrane of the cell. Because the membrane permeability for potassium is much higher than that for other ions (disregarding voltage-gated channels at this stage), and because of the strong chemical gradient for potassium, potassium ions flow from the cytosol into the extracellular space carrying out positive charge, until their movement is balanced by build-up of negative charge on the inner surface of the membrane. Again, because of the high relative permeability for potassium, the resulting membrane potential is almost always close to the potassium reversal potential. But in order for this process to occur, a concentration gradient of potassium ions must first be set up. This work is done by the ion pumps/transporters and/or exchangers and generally is powered by ATP.In the case of the resting membrane potential across an animal cell's plasma membrane, potassium (and sodium) gradients are established by the Na+/K+-ATPase (sodium-potassium pump) which transports 2 potassium ions inside and 3 sodium ions outside at the cost of 1 ATP molecule. In other cases, for example, a membrane potential may be established by acidification of the inside of a membranous compartment (such as the proton pump that generates membrane potential across synaptic vesicle membranes).
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