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Large-scale cognitive model design using the Nengo neural simulator
Large-scale cognitive model design using the Nengo neural simulator

Realizing Biological Spiking Network Models in a Configurable
Realizing Biological Spiking Network Models in a Configurable

... this hardware architecture: First, a continuous-time serial bus system using on-chip and post-processing lines for intrawafer communication (“Layer-1”). Second, a packet-based dynamic routing network implemented by separate custom hardware components which interface the network chips via contacts on ...
Dynamics of Spontaneous Activity in Neocortical Slices
Dynamics of Spontaneous Activity in Neocortical Slices

... neocortical brain slices can sustain spontaneous activity. In the past, slices have been used to study the responses of neurons to electrical or pharmacological stimulations. At the same time, EPSPs and IPSPs are routinely recorded intracellularly from neurons in slices even under conditions in whic ...
Neural Syntax: Cell Assemblies, Synapsembles, and
Neural Syntax: Cell Assemblies, Synapsembles, and

... frame. Neurons come together in transient time frames to produce a composite downstream effect, which cannot be achieved by single neurons alone. The most important modus operandi in this process is synchrony of events (Abeles, 1991; Engel et al., 2001; Fries et al., 2007; Hansel and Sompolinsky, 19 ...
Efficient Recruitment of Layer 2/3 Interneurons by Layer 4 Input in
Efficient Recruitment of Layer 2/3 Interneurons by Layer 4 Input in

... mM PB, pH 7.4, containing either 4% paraformaldehyde or 1% paraformaldehyde and 2.5% glutaraldehyde. Slices containing biocytinfilled neurons that were destined for lightmicroscopic analysis only, were processed using a modified protocol described previously (Lübke et al., 2000). Slices were incuba ...
Efficient Event-Driven Simulation of Large Networks of Spiking
Efficient Event-Driven Simulation of Large Networks of Spiking

A Neuronal Model of Predictive Coding Accounting for the
A Neuronal Model of Predictive Coding Accounting for the

... However, a detailed neuronal model of the neurobiological mechanisms underlying the MMN is still lacking, and its computational foundations remain debated. We propose here a detailed neuronal model of auditory cortex, based on predictive coding, that accounts for the critical features of MMN. The mo ...
1 also mediates MMP-2 and MMP-9 activation. In our
1 also mediates MMP-2 and MMP-9 activation. In our

... resulting in paralysis and ultimately death. Disturbances in glutamate homeostasis, which lead to toxic accumulation of this excitatory neurotransmitter in the synaptic cleft, are observed in several neuropathologies notably in ALS. It has been recently shown that neuromuscular junction (NMJ) loss a ...
Relationship of Activity in the Subthalamic Nucleus–Globus Pallidus
Relationship of Activity in the Subthalamic Nucleus–Globus Pallidus

... Rhythmic activity in STN and GP neurons was lost when the cortex was inactivated by spreading depression and did not resume until SWA had recovered. ...
Neurons, Neural Networks, and Learning
Neurons, Neural Networks, and Learning

... membership is recognized correctly. If so, no action is required. If not, a learning rule must be applied to adjust the weights. • This iterative process has to continue either until for all vectors from the learning set their membership will be recognized correctly or it will not be recognized just ...
Excitation of Ventral Tegmental Area Dopaminergic and
Excitation of Ventral Tegmental Area Dopaminergic and

... Slice preparation and electrophysiology. Coronal brain slices were prepared from 3- to 4-week-old male Wistar rats as described previously (Korotkova et al., 2002). Slices (400 ␮m thick) were cut at the level of the rostral VTA using a vibroslicer (Campden Instruments, Loughborough, UK). After slici ...
Serotonin release from the neuronal cell body and its long
Serotonin release from the neuronal cell body and its long

... and from development to disease (for review, see [5]). Serotonin acts in every moment of our lives, and failures of our serotonergic system produce depression, bipolar disorder or posttraumatic stress disorder among other syndromes. In newborns, serotonergic failures may cause sudden death [6]. The ...
Fig. - Development - The Company of Biologists
Fig. - Development - The Company of Biologists

... maps of connectivity matching the distribution and density of sensory receptors of facial dermatomes are generated at all levels of the pathway (Erzurumlu and Killackey, 1983; Erzurumlu et al., 2010; Ma, 1991, 1993; Ma and Woolsey, 1984; Schlaggar and O’Leary, 1993; Van Der Loos, 1976; Woolsey and V ...
Facial whisker pattern is not sufficient to instruct a
Facial whisker pattern is not sufficient to instruct a

... maps of connectivity matching the distribution and density of sensory receptors of facial dermatomes are generated at all levels of the pathway (Erzurumlu and Killackey, 1983; Erzurumlu et al., 2010; Ma, 1991, 1993; Ma and Woolsey, 1984; Schlaggar and O’Leary, 1993; Van Der Loos, 1976; Woolsey and V ...
A Candidate Pathway for a Visual Instructional Signal to the Barn
A Candidate Pathway for a Visual Instructional Signal to the Barn

... located within the circle marked by arrowheads; stained terminal structures are marked by the arrow. Giemsa counterstain; scale bar, 100 ␮m. least 4 hr were allowed for transport. After fixation, brains and slices were sectioned on a cryostat at 60 ␮m, and the biocytin was visualized with a heav y-m ...
Lecture 11 - Websupport1
Lecture 11 - Websupport1

... • Sympathetic activation is controlled by sypathetic centers in the hypothalamus. • In crises, the entire sympathetic division ...
doc GIT
doc GIT

... There are 2 types of contractile activity within the GIT: o The length of the GIT periodically contracts at various points which gives rise to sausage-like segments. These are followed by periods of relaxation. → Very effective mixing mvt. They can also be involved in the propulsion of the meal away ...
SOMATIC NERVOUS SYSTEM Composed of somatic parts of CNS
SOMATIC NERVOUS SYSTEM Composed of somatic parts of CNS

Patterns of neuronal migration in the embryonic cortex
Patterns of neuronal migration in the embryonic cortex

... in the MZ before turning again to enter the cortical plate to reach their final positions [36]. Interestingly, a proportion of tangentially migrating neurons from all cortical layers were observed to undergo ventricle-directed migration to the VZ in slice-culture preparations [37]. Upon reaching the ...
Non-NMDA and NMDA receptors transmit area postrema input to
Non-NMDA and NMDA receptors transmit area postrema input to

... medulla above the fourth ventricle, the AP is well suited for this modulatory function: it lacks a complete blood-brain barrier, making it accessible to circulating substances with cardiovascular-related actions, including angiotensin II, vasopressin, and endothelin (9, 10, 19, 34), and it sends pro ...
Wang et al 2photon calcium imaging of odor in fly brain cell 2003
Wang et al 2photon calcium imaging of odor in fly brain cell 2003

... mechanism of odor discrimination has been shared, despite the five hundred million years of evolution separating insects from mammals. The convergence of like axons into discrete glomerular structures provides a map of receptor activation in the first relay station for olfactory information in the b ...
Extra-Classical Tuning Predicts Stimulus
Extra-Classical Tuning Predicts Stimulus

... nonlinear response properties, different classes of stimuli drive a neuron along different regions of a nonlinear stimulus–response curve. Determining the degree to which RF nonlinearities influence stimulus-dependent STRFs and experimentally characterizing such nonlinearities are important for unde ...
ECE 517 Final Project Development of Predator/Prey Behavior via Reinforcement Learning
ECE 517 Final Project Development of Predator/Prey Behavior via Reinforcement Learning

... Despite this constrained space, results were still poor. The robots continued to just spin in circles showing no real signs of learning. Experimentations with different gamma values and reward schemes yielded identical results. Clearly, either the problem theory was incorrect, or the problem was sti ...
A Taxonomy of the Evolution of Artificial Neural Systems Helmut A
A Taxonomy of the Evolution of Artificial Neural Systems Helmut A

Big Myth or Major Miss? - Perceptual Science Laboratory
Big Myth or Major Miss? - Perceptual Science Laboratory

... claims  of  embodied  cognition  such  as  a)  perception  and  action  are  intimately  linked,   and  b)  what  appears  to  be  high-­‐level  or  abstract  cognitive  phenomena  (e.g.,   language,  goal  understanding,  mind  reading)  a ...
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Central pattern generator

Central pattern generators (CPGs) are biological neural networks that produce rhythmic patterned outputs without sensory feedback. CPGs have been shown to produce rhythmic outputs resembling normal ""rhythmic motor pattern production"" even in isolation from motor and sensory feedback from limbs and other muscle targets. To be classified as a rhythmic generator, a CPG requires:1. ""two or more processes that interact such that each process sequentially increases and decreases, and 2. that, as a result of this interaction, the system repeatedly returns to its starting condition.
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