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Distinct Requirements for Evoked and Spontaneous Release of
Distinct Requirements for Evoked and Spontaneous Release of

... incision, and the flaps of cuticle were glued to the slide. The gut, fat bodies, and connective tissue then were removed to expose the C NS and musculature. Dissections were performed in HL3 physiological solution, as described by Stewart et al. (1994). The dissected preparations were fixed in Bouin ...
chapter3_part1 Membrane lecture
chapter3_part1 Membrane lecture

... • Exocytosis -- releases substances into the ECF • The rate of endocytosis and exocytosis must be balanced to maintain a constant membrane surface area and cell volume • Caveolae may play a role in transport of substances and cell signaling ...
The Cellular Level of Organization • Basic, living, structural and
The Cellular Level of Organization • Basic, living, structural and

... The Cellular Level of Organization Basic, living, structural and functional unit of the body – compartmentalization of chemical reactions within specialized structures – regulate inflow & outflow of materials – use genetic material to direct cell activities Cytology = study of cellular structure Cel ...
2281-MC-025 Bax 6A7 for pdf
2281-MC-025 Bax 6A7 for pdf

... mitochondria during apoptosis, and overexpression of Bax can accelerate cell death. Coregulation of Bax dimer formation and intracellular localization are associated with Bax conformational changes. Anti-Bax 6A7 is conformation dependent and will recognize detergent treated but not native Bax. When ...
Biology 212: January 30, 2002
Biology 212: January 30, 2002

...  Note: the sodium gradient isn’t appreciably changed. Even after even many APs, there are still far more sodium ions outside the cell than inside.  After that, permeability to sodium ions rapidly decreases again. This is because each channel is programmed to be open for only about 0.5 msec. It the ...
Human Physiology
Human Physiology

... Endosomes (内小体) and lysosomes form the endomembrane system ...
Topic 5
Topic 5

... Note: Because the gap junction is able to allow ion flow in either direction, the effect is to make electrical synapses BIDIRECTIONAL. This difference means that neural circuits with electrical synapses can perform quite differently than those with chemical synapses. Typically the channel created b ...
Hydrophobic-at-Interface Regions in Viral Fusion Protein Ectodomains
Hydrophobic-at-Interface Regions in Viral Fusion Protein Ectodomains

... An important characteristic shared by many of these polypeptides, known for quite a long time as being crucial for the development of their fusogenic function, is the presence of a fusion peptide within the ectodomain exposed to the water phase (Gallaher, 1987; White, 1992). This hydrophobic and con ...
SI October 7, 2008
SI October 7, 2008

... What is the “work” that can be accomplished by the electrochemical gradients built into the neuron at rest and why is this essential for the nervous system? 1) Secondary Active Transport: A sodium concentration gradient pointing into the cell ([Na+] OUT > [Na+] IN) can be utilized to transport subst ...
Ribosomes - juan-roldan
Ribosomes - juan-roldan

... •Nuclear envelope is connected to rough ER •Proteins produced by the ER flow in transport vessicles to the Golgi •Golgi pinches off vessicles that give rise to lysosomes, vessicles and vacuoles •Lysosomes can fuse with another vessicle for digestion •Transport vessicle carries proteins to plasma mem ...
Peptides - Alfred State College
Peptides - Alfred State College

... Working with Proteins Today’s Objectives: to understand • The structure and properties of peptides • The ionization behavior of and peptides • Various methods to characterize peptides and proteins ...
Document
Document

... chemical-gated ion channels called neuroreceptors. These have specific binding sites for neurotransmitters. ...
REVIEWS How membrane proteins travel across the mitochondrial
REVIEWS How membrane proteins travel across the mitochondrial

... the precursor. Equally plausible is a model in which the 70 kDa complexes form a link between the TOM and the TIM complexes. In this model, the precursor is not released into the intermembrane space but binds to the small Tim proteins as it emerges from the TOM complex. Further transfer to the Tim22 ...
PPT #2 Membrane Diffusion Water
PPT #2 Membrane Diffusion Water

... How do you build a semi-permeable cell membrane?  What molecule will sit “comfortably” in a phospholipid bilayer forming channels ...
Lecture 9 MEMBRANES
Lecture 9 MEMBRANES

... Low-angle x-ray diffraction analysis of myelin membranes This technique measures the density of matter and can be used to determine the distribution of lipid and protein in biomembranes. (a) During development of the nervous system, a large Schwann cell envelops the axon of a neuron. The continuous ...
Neuromuscular junctions
Neuromuscular junctions

... the large muscle cell by invaginations in the cell membrane called T-tubules. ...
- blogs@NTU
- blogs@NTU

... track individual vesicles and their cargos in real time; however, affinity purification allows vesicles to be isolated in their natural state so that their constituent proteins can be identified. Pioneering this approach in plants, we isolated the SYP61 trans-Golgi network compartment and carried ou ...
Supplementary Table VI. List of Deletions/Hypomorphic Alleles
Supplementary Table VI. List of Deletions/Hypomorphic Alleles

... COPII vesicle coat protein required for ER transport vesicle budding; Sec16p is bound to the periphery of ER membranes and may act to stabilize initial COPII complexes; interacts with Sec23p, Sec24p and Sec31p Peripheral membrane protein required for vesicular transport between ER and Golgi, the 'pr ...
Neurons & Nervous Systems
Neurons & Nervous Systems

... – connects CNS to effectors ...
Lh6Ch10Lipids
Lh6Ch10Lipids

... – Done to increase shelf life or stability at high temperature of oils used in cooking (especially deep frying) • A trans double bond allows a given fatty acid to adopt an extended conformation • Trans fatty acids can pack more regularly and show higher melting points than cis forms • Consuming tran ...
Document
Document

... ER to the Golgi apparatus. What other organelles and membranes are affected? A. lysosomes, transport vesicles, plasma membrane B. mitochondria, peroxisomes, plasma membrane C. vacuoles, mitochondria, plasma membrane D. lysosomes, transport vesicles, nuclear membrane E. all intracellular organelles a ...
A short guided tour through functional and structural features of
A short guided tour through functional and structural features of

... domain, and accordingly is absent in the mature protein, the hypothesis arose that it might also act independently as a part of the plant defence mechanism against pathogens [66]. Like other SAPLIPs, it prefers negatively charged lipids and low pH. Another possible and perhaps additional function su ...
Electrochemical Impulse
Electrochemical Impulse

...  It is by this restriction that saltatory conduction propagates an action potential along the axon of a neuron at rates significantly higher than would be possible without the myelination of the axon (200 m/s compared to 2 m/s) ...
2014-2015 Summer Work Packet
2014-2015 Summer Work Packet

... Directions: As you carefully read through chapters 1-7 in your Campbell Biology textbook, thoughtfully respond to each of the following questions. It is important that you actually read the chapters for review and understanding. Do not just look for answers to the questions provided. Review all diag ...
Cell Membrane
Cell Membrane

...  On outer surfaces of membrane in fluid ...
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SNARE (protein)



SNARE proteins (an acronym derived from ""SNAP (Soluble NSF Attachment Protein) REceptor"") are a large protein superfamily consisting of more than 60 members in yeast and mammalian cells. The primary role of SNARE proteins is to mediate vesicle fusion, that is, the fusion of vesicles with their target membrane bound compartments (such as a lysosome). The best studied SNAREs are those that mediate docking of synaptic vesicles with the presynaptic membrane in neurons. These SNAREs are the targets of the bacterial neurotoxins responsible for botulism and tetanus.
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