Mendel and Punnett Notes
									
... • A tool to predict the probability of certain traits in offspring that shows the different ways alleles can combine • A way to show phenotype & genotype • A chart that shows all the possible combinations of alleles that can result ...
                        	... • A tool to predict the probability of certain traits in offspring that shows the different ways alleles can combine • A way to show phenotype & genotype • A chart that shows all the possible combinations of alleles that can result ...
									File S1
									
... (hippocampus), blue (neocortex), and red (hypothalamus). Genes are marked with blue if they are only present in the neocortex list. If one other region has differential expression of that gene, it is marked with the color of "the second region". If a gene is differentially expressed in more than 2 r ...
                        	... (hippocampus), blue (neocortex), and red (hypothalamus). Genes are marked with blue if they are only present in the neocortex list. If one other region has differential expression of that gene, it is marked with the color of "the second region". If a gene is differentially expressed in more than 2 r ...
									Know Before You Buy! Teacher Guide - Science Take-Out
									
... switching genes off when the proteins they produce are not needed. Genes for proteins that are only needed under certain conditions are regulated by “on‐off switches.” ...
                        	... switching genes off when the proteins they produce are not needed. Genes for proteins that are only needed under certain conditions are regulated by “on‐off switches.” ...
									Guo, Ming: Biological Pathways - A pathway to explore diseases mechanism
									
... The methods abovementioned aim at inferring pathway representation directly from the gene expression data of each gene. All these approaches implicitly assume each gene as target for enrichment. The gene set approach, on the other hand, treats the known functionally related genes together as a group ...
                        	... The methods abovementioned aim at inferring pathway representation directly from the gene expression data of each gene. All these approaches implicitly assume each gene as target for enrichment. The gene set approach, on the other hand, treats the known functionally related genes together as a group ...
									Haoyang Zeng, Michela Meister, Subarna Sinha, David L. Dill
									
... • We made up virtual genes of each subtype by evaluating the table in [1] which maps from each sample to subtype. • Subtype virtual genes revealed the same signature as in [1], which are selectively show as below. ...
                        	... • We made up virtual genes of each subtype by evaluating the table in [1] which maps from each sample to subtype. • Subtype virtual genes revealed the same signature as in [1], which are selectively show as below. ...
									portable document (.pdf) format
									
... Several proposals have been made for detecting differential genes in two-class microarray studies, such as Lyons-Weiler et al. (2004). One widely used approach is to compute t-statistic Ti for each gene, and call the gene DE if the |Ti | exceeds a certain threshold. This t-statistic has a similar de ...
                        	... Several proposals have been made for detecting differential genes in two-class microarray studies, such as Lyons-Weiler et al. (2004). One widely used approach is to compute t-statistic Ti for each gene, and call the gene DE if the |Ti | exceeds a certain threshold. This t-statistic has a similar de ...
									Correlations Between Gene Expression and Gene Conservation in
									
... (P < 10ⳮ21). Moreover, pombe-specific genes were underrepresented among genes repressed during sexual differentiation, contributing only 5.9% of those genes (P < 10ⳮ7). We defined “pombe-specific genes” as those not shared with the S. cerevisiae and C. elegans genomes. To confirm these results, we u ...
                        	... (P < 10ⳮ21). Moreover, pombe-specific genes were underrepresented among genes repressed during sexual differentiation, contributing only 5.9% of those genes (P < 10ⳮ7). We defined “pombe-specific genes” as those not shared with the S. cerevisiae and C. elegans genomes. To confirm these results, we u ...
									Hox Genes in Development and Disease – Lecture 2
									
... double mutants have no genital tubercle, hands or feet. Sonic hedgehog mutant mice no genital tubercle at all. The hypospadias in Hand-Foot-Genital Syndrome is caused by failure of urethral folding. A more frequent cause of hypospadias in humans is hormonal teratogenesis during pregnancy (e.g., diet ...
                        	... double mutants have no genital tubercle, hands or feet. Sonic hedgehog mutant mice no genital tubercle at all. The hypospadias in Hand-Foot-Genital Syndrome is caused by failure of urethral folding. A more frequent cause of hypospadias in humans is hormonal teratogenesis during pregnancy (e.g., diet ...
									bicoid - Blumberg Lab
									
... – You need to learn everything. • ultimately, you will need to know this stuff for MCAT and GRE • may as well learn it now while we are here to explain the parts that may not be completely clear ...
                        	... – You need to learn everything. • ultimately, you will need to know this stuff for MCAT and GRE • may as well learn it now while we are here to explain the parts that may not be completely clear ...
									Gene Section IGL@ (Immunoglobulin Lambda) Atlas of Genetics and Cytogenetics
									
... consists of 70 to 71 IGLV genes, localized on 900 kb, 7 to 11 IGLJ and 7 to 11 IGLC genes depending on the haplotypes, each IGLC gene being preceded by one IGLJ segment. Fifty-six to 57 genes belong to 11 subgroups, whereas 14 pseudogenes which are too divergent to be assigned to subgroups have been ...
                        	... consists of 70 to 71 IGLV genes, localized on 900 kb, 7 to 11 IGLJ and 7 to 11 IGLC genes depending on the haplotypes, each IGLC gene being preceded by one IGLJ segment. Fifty-six to 57 genes belong to 11 subgroups, whereas 14 pseudogenes which are too divergent to be assigned to subgroups have been ...
									chromosome 17
									
... • Increases or decreases in size do not correlate with number of genes • Polyploidy in plants does not by itself explain differences in genome size • A greater amount of DNA is explained by the presence of introns and nonprotein-coding sequences than gene duplicates ...
                        	... • Increases or decreases in size do not correlate with number of genes • Polyploidy in plants does not by itself explain differences in genome size • A greater amount of DNA is explained by the presence of introns and nonprotein-coding sequences than gene duplicates ...
									Gene Net Analysis: Motifs vs. Correlation
									
... Involves thousands of genes while current data sets contain a few dozen samples. This raises problems in computational complexity and the statistical significance of the results. Genetic regulation networks are sparse (gene assumed to have no more than a few dozen genes directly affect its transcrip ...
                        	... Involves thousands of genes while current data sets contain a few dozen samples. This raises problems in computational complexity and the statistical significance of the results. Genetic regulation networks are sparse (gene assumed to have no more than a few dozen genes directly affect its transcrip ...
									REDUNDANCY OF GENOTYPES AS THE WAY FOR SOME
									
... analogy to biological organisms, chromosomes contain two sets of genes. The first is a set of so-called phenotype genes, that is, the genes which are expressed in the organism’s phenotype. The second set consists of the genes which are redundant, they are called also latent genes, because they do no ...
                        	... analogy to biological organisms, chromosomes contain two sets of genes. The first is a set of so-called phenotype genes, that is, the genes which are expressed in the organism’s phenotype. The second set consists of the genes which are redundant, they are called also latent genes, because they do no ...
									Domestication genes in plants
									
... silica deposition in cells, three-dimensional organ growth, and organ size •The difference in function between the maize and teosinte alleles of tga1 appears to be the result of a single amino acid change. The fact that there are no discernable differences in gene expression supports this interpreta ...
                        	... silica deposition in cells, three-dimensional organ growth, and organ size •The difference in function between the maize and teosinte alleles of tga1 appears to be the result of a single amino acid change. The fact that there are no discernable differences in gene expression supports this interpreta ...
									Lesson 13: Polygenic Inheritance student notes
									
... DNA sequence for “A” allele DNA sequence for “a” allele Paternal 3 ...
                        	... DNA sequence for “A” allele DNA sequence for “a” allele Paternal 3 ...
									Flatworms and Evolution
									
... • Mutations cause phenotypes of homeosis (segments are transformed into the likeness of a different segment) • Striking property of this complex is colinearity •A-P body plan in other bilaterally symmetrical animals, (including mice) is determined by Orthologs of the fruit fly genes. Orthologs: homo ...
                        	... • Mutations cause phenotypes of homeosis (segments are transformed into the likeness of a different segment) • Striking property of this complex is colinearity •A-P body plan in other bilaterally symmetrical animals, (including mice) is determined by Orthologs of the fruit fly genes. Orthologs: homo ...
									Medelian Genetics Notes
									
... Different notation: Use first letter of the feature with a superscript for the trait. Example: CW or CR for white petals or red petals; ...
                        	... Different notation: Use first letter of the feature with a superscript for the trait. Example: CW or CR for white petals or red petals; ...
									CHAPTER 4
									
... because the map distance is 7 cM. Because of the complete interference, a crossover on one side of the centromere precludes a crossover on the other side, so these asci must have first-division segregation for pan-2. (b) Similarly, the frequency of second-division segregation of pan-2 must be 6 perc ...
                        	... because the map distance is 7 cM. Because of the complete interference, a crossover on one side of the centromere precludes a crossover on the other side, so these asci must have first-division segregation for pan-2. (b) Similarly, the frequency of second-division segregation of pan-2 must be 6 perc ...
									File
									
... He hypothesized that the frequency of recombinant offspring reflected the distances between genes on a chromosome. The farther apart two genes are, the higher the probability that a crossover will occur between them and therefore a higher recombination frequency. ...
                        	... He hypothesized that the frequency of recombinant offspring reflected the distances between genes on a chromosome. The farther apart two genes are, the higher the probability that a crossover will occur between them and therefore a higher recombination frequency. ...
									Ribosomal RNA Genes Investigation Part I: Gene Copy Number The
									
... 20th Century molecular biology was recognizing the essential role of rRNAs, and the Harry Noller Lab at UCSC made sustained and essential contributions to this field of research. Let's see if we can use some basic bioinformatics tools to learn more about the functional organization and evolution of ...
                        	... 20th Century molecular biology was recognizing the essential role of rRNAs, and the Harry Noller Lab at UCSC made sustained and essential contributions to this field of research. Let's see if we can use some basic bioinformatics tools to learn more about the functional organization and evolution of ...
									Ch. 9 Patterns of Inheritance (Lecture Notes)
									
... 9.10 Incomplete dominance results in intermediate phenotypes Incomplete dominance describes the situation where one allele is not completely dominant in the heterozygote; the heterozygote usually exhibits characteristics intermediate between both homozygous conditions. Inheritance of alleles that re ...
                        	... 9.10 Incomplete dominance results in intermediate phenotypes Incomplete dominance describes the situation where one allele is not completely dominant in the heterozygote; the heterozygote usually exhibits characteristics intermediate between both homozygous conditions. Inheritance of alleles that re ...
									File - Varsity Field
									
... From meiosis, what combinations of chromosomes and alleles are possible in the gametes if we consider the effect of independent assortment? We will use the example of two pairs of nonhomologous chromosomes. The first chromosome is colored orange and the second blue for tracking. Sister and nonsister ...
                        	... From meiosis, what combinations of chromosomes and alleles are possible in the gametes if we consider the effect of independent assortment? We will use the example of two pairs of nonhomologous chromosomes. The first chromosome is colored orange and the second blue for tracking. Sister and nonsister ...
Essential gene
                        Essential genes are those genes of an organism that are thought to be critical for its survival. However, being essential is highly dependent on the circumstances in which an organism lives. For instance, a gene required to digest starch is only essential if starch is the only source of energy. Recently, systematic attempts have been made to identify those genes that are absolutely required to maintain life, provided that all nutrients are available. Such experiments have led to the conclusion that the absolutely required number of genes for bacteria is on the order of about 250-300. These essential genes encode proteins to maintain a central metabolism, replicate DNA, translate genes into proteins, maintain a basic cellular structure, and mediate transport processes into and out of the cell. Most genes are not essential but convey selective advantages and increased fitness.