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Neuronal cell types
Neuronal cell types

... intrinsic neuron can receive synaptic inputs from cells located within the same structure or from distant ones. The following paragraphs give examples of neuronal types in the cerebellum and the retina, where the types are pretty well understood, and the neocortex, which has proved a much harder nut ...
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... While oxidative stress has been strongly implicated in the pathogenesis of Parkinson’s disease (PD), the molecular mechanism underlying selective vulnerability of the nigrostriatal dopaminergic pathway to oxidative damage remains unknown. Increased levels of reactive oxygen species (ROS) result in a ...
Chapter 2 Power Point: The Biological Perspective
Chapter 2 Power Point: The Biological Perspective

... • Chemical substances can affect neuronal communication. • Agonists - mimic or enhance the effects of a neurotransmitter on the receptor sites of the next cell, increasing or decreasing the activity of that cell. • Antagonists - block or reduce a cell’s response to the action of other chemicals or n ...
FEATURE ARTICLE Summation of Unitary IPSPs
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... on-the-path shunting mechanisms (Koch, 1999) were suppressed in the case studied here. This could be due to the relatively high density of voltage gated ion channels on the AIS decreasing the significance of the synaptic conductance changes. The involvement of voltage activated currents, such as de- ...
English - Bernstein Center for Computational Neuroscience Berlin
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... Masked fears Fear is a natural part of our emotional life and acts as a necessary protection mechanism. However, fears sometimes grow beyond proportions and become difficult to shed. Scientists from Freiburg, Basel and Bordeaux have used computer simulations to understand the processes within the br ...
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Finding Clues to Schizophrenia Outside Neurons
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doc Phgy 210 Lecture 25 notes

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Slideshow - Roswell Park Cancer Institute

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... – Gustatory cells - specialized receptors located on each taste bud (50-125 per taste bud); have special hair like projections (sensitive to various chemicals acts as stimuli for various taste sensations) – gustatory nerves - connected by the cranial nerves to the medulla oblongata  relays the mess ...
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... area. Model demyelination of an axon, and understand its impact on neural transmission. Background (from “Bridging Physics and Biology Using Resistance and Axons” by Joshua M. Dyer): Neurons are nerve cells that are composed of three major sections, as shown in Fig. 1: the dendrites, the cell body, ...
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Nervous System - Neuron and Nerve Impulse PowerPoint

... the flow of ions at the point of the impulse causes sodium channels just ahead of it to open. This allows the impulse to move rapidly along the axon. – The flow of an impulse can be compared to the fall of a row of dominoes. As each domino falls, it causes the next domino to fall. An action potentia ...
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Exam - McLoon Lab

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Brain Waves Volunteer Instructor Guide
Brain Waves Volunteer Instructor Guide

... The human brain is made of 100 billion cells called neurons. Neurons are different from other cells in our body because they have special branches that come out from the centre of the neuron (the cell body or soma). Each neuron passes signals from one neuron to the next. The branches that receive in ...
Slide
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... • 1 OR expressed/neuron; can detect many odorants • Even though many OR genes initially selected for expression, only one will dominate and remain expressed • Odorant sensory neurons converge on a few glomeruli in the OB • Partially overlapping combinations of OR inputs generate distinct odor percep ...
doc Lecuter and chapter notes
doc Lecuter and chapter notes

... can be neutralized by the opening of chlorine channels, which will flood into a cell that’s been depolarized and thereby return its membrane potential to the resting level  when calcium channels open, they also stimulate the production of certain enzymes, which causes some other changes to the cell ...
Poster
Poster

... naturally synthesized by the body. Agonists of the KOP receptor, such as salvinorin A, are effective at reducing pain without activating the reward pathway that leads to dependence. However, the KOP receptor is associated with its own set of adverse effects including dysphoria and hallucination. Und ...
Ionic Mechanism of the Slow Afterdepolarization Induced by
Ionic Mechanism of the Slow Afterdepolarization Induced by

... 1998. The mammalian prefrontal cortex receives a dense cholinergic innervation from subcortical regions. We previously have shown that cholinergic stimulation of layer V pyramidal neurons of the rat prefrontal cortex results in a depolarization and the appearance of a slow afterdepolarization (sADP) ...
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Molecular neuroscience



Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject primarily pertains to a reductionist view of neuroscience, considering topics such as molecular neuroanatomy, mechanisms of molecular signaling in the nervous system, the effects of genetics on neuronal development, and the molecular basis for neuroplasticity and neurodegenerative diseases. As with molecular biology, molecular neuroscience is a relatively new field that is considerably dynamic.
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