![A Psychomotor Stimulant Theory of Addiction](http://s1.studyres.com/store/data/016038223_1-64de70768c3e1b1eafe18dd0ef00c2db-300x300.png)
A Psychomotor Stimulant Theory of Addiction
... However, although it can be argued that there is some form of dependence syndrome associated with habitual use of every addicting drug, the same dependence syndrome is not common to all drugs. The dependence syndromes associated with different drugs are thus not homologous, but merely analogous. Phy ...
... However, although it can be argued that there is some form of dependence syndrome associated with habitual use of every addicting drug, the same dependence syndrome is not common to all drugs. The dependence syndromes associated with different drugs are thus not homologous, but merely analogous. Phy ...
BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS
... (minimum effective concentrations) for pain suppression and avoidance of drug toxicity, monitoring of drug levels has been considered essential to determine drug concentrations in plasma A new reverse phase high-performance liquid chromatography (RP-HPLC) assay was developed for the simultaneous det ...
... (minimum effective concentrations) for pain suppression and avoidance of drug toxicity, monitoring of drug levels has been considered essential to determine drug concentrations in plasma A new reverse phase high-performance liquid chromatography (RP-HPLC) assay was developed for the simultaneous det ...
Enhancement of naturally acquired immunity against malaria by
... years, the majority of these volunteers was still fully protected against a CHMI. Long-lasting cellular immune responses, more specifically multifunctional effector memory T-cells that produce both IFN-c and interleukin-2 upon ex vivo stimulation, are associated with protection (Roestenberg et al., ...
... years, the majority of these volunteers was still fully protected against a CHMI. Long-lasting cellular immune responses, more specifically multifunctional effector memory T-cells that produce both IFN-c and interleukin-2 upon ex vivo stimulation, are associated with protection (Roestenberg et al., ...
PRAG
... with the same overall structure as a Monograph on a chemical substance The latest versions of the Technical Guide for the Elaboration of Mongraphs and of the Style Guide apply to monographs on Herbal Drugs All Tests and Assay methods described in a monograph must be validated according to the proced ...
... with the same overall structure as a Monograph on a chemical substance The latest versions of the Technical Guide for the Elaboration of Mongraphs and of the Style Guide apply to monographs on Herbal Drugs All Tests and Assay methods described in a monograph must be validated according to the proced ...
DMSO: Many Uses, Much Controversy
... The history of DMSO as a pharmaceutical began in 1961, when Dr. Jacob was head of the organ transplant program at Oregon Health Sciences University. It all started when he first picked up a bottle of the colorless liquid. While investigating its potential as a preservative for organs, he quickly dis ...
... The history of DMSO as a pharmaceutical began in 1961, when Dr. Jacob was head of the organ transplant program at Oregon Health Sciences University. It all started when he first picked up a bottle of the colorless liquid. While investigating its potential as a preservative for organs, he quickly dis ...
Drug - University of Washington
... Bactericidal. Inhibits cell wall synthesis by binding to PBPs; sulbactam is a β lactamase inhibitor ...
... Bactericidal. Inhibits cell wall synthesis by binding to PBPs; sulbactam is a β lactamase inhibitor ...
TASTE MASKED ORODISPERSIBLE TABLETS: A HIGHLY
... In fast-dissolving/disintegrating tablets include sweeteners and flavors for taste-masking, but many drugs are extremely bitter and that bitter taste cannot be masked by taste masking agent. In these cases, taste is masked by various technologies as given below then they are converted into FDT. Some ...
... In fast-dissolving/disintegrating tablets include sweeteners and flavors for taste-masking, but many drugs are extremely bitter and that bitter taste cannot be masked by taste masking agent. In these cases, taste is masked by various technologies as given below then they are converted into FDT. Some ...
PART II
... “Education about drugs based on life skills” refers to a series of interactive sessions delivered in schools aimed at providing students with the information and the personal and social skills needed to avoid or delay first-time use of illicit drugs (United Nations Office on Drugs and Crime (UNODC)) ...
... “Education about drugs based on life skills” refers to a series of interactive sessions delivered in schools aimed at providing students with the information and the personal and social skills needed to avoid or delay first-time use of illicit drugs (United Nations Office on Drugs and Crime (UNODC)) ...
Hydrocodone Bitartrate
... moderately severe pain. This drug should be given in the smallest effective dose and as infrequently as possible to minimize the development of tolerance and physical dependence. Hydrocodone bitartrate is available in the United States only in fixed combinations with non-opiate drugs (e.g., acetamin ...
... moderately severe pain. This drug should be given in the smallest effective dose and as infrequently as possible to minimize the development of tolerance and physical dependence. Hydrocodone bitartrate is available in the United States only in fixed combinations with non-opiate drugs (e.g., acetamin ...
PART II - United Nations Office on Drugs and Crime
... “Education about drugs based on life skills” refers to a series of interactive sessions delivered in schools aimed at providing students with the information and the personal and social skills needed to avoid or delay first-time use of illicit drugs (United Nations Office on Drugs and Crime (UNODC)) ...
... “Education about drugs based on life skills” refers to a series of interactive sessions delivered in schools aimed at providing students with the information and the personal and social skills needed to avoid or delay first-time use of illicit drugs (United Nations Office on Drugs and Crime (UNODC)) ...
In Vitro Nail Penetration of Nitric Oxide
... released from several unique drug product formulations (gel, cream, lacquer), to penetrate the human nail and effectively kill the fungal infection. Methods: In vitro human nail penetration was evaluated (MedPharm, Guilford, UK) utilizing the ChubTur® infected human nail assay. Tricophyton rubrum (T ...
... released from several unique drug product formulations (gel, cream, lacquer), to penetrate the human nail and effectively kill the fungal infection. Methods: In vitro human nail penetration was evaluated (MedPharm, Guilford, UK) utilizing the ChubTur® infected human nail assay. Tricophyton rubrum (T ...
Evaluating Drugs Used To Treat: Constipation
... Changes in routine – Many people become constipated while traveling, especially when it involves large time zone differences. Whether for business or pleasure, travel usually involves changes in your regular daily eating and sleeping habits, physical activity, and toilet routines. These changes can ...
... Changes in routine – Many people become constipated while traveling, especially when it involves large time zone differences. Whether for business or pleasure, travel usually involves changes in your regular daily eating and sleeping habits, physical activity, and toilet routines. These changes can ...
Pulmonary Drug Absorption
... intensity, and duration of action of the drug (Taylor G., 1990). Although inhalation is a well established means for drug administration, drug absorption kinetics in the lung has not been subjected to extensive research. Yet, investigations of the absorption rate and bioavailability of pulmonary del ...
... intensity, and duration of action of the drug (Taylor G., 1990). Although inhalation is a well established means for drug administration, drug absorption kinetics in the lung has not been subjected to extensive research. Yet, investigations of the absorption rate and bioavailability of pulmonary del ...
SIMULTANEOUS DETERMINATION OF CLOPIDOGREL AND
... Pioglitazone is used for the treatment of diabetes mellitus type 2 (previously known as noninsulin-dependent diabetes mellitus, NIDDM) in monotherapy and in combination with asulfonylurea, metformin, or insulin. Pioglitazone has also been used to treat non-alcoholic steatohepatitis (fatty liver), bu ...
... Pioglitazone is used for the treatment of diabetes mellitus type 2 (previously known as noninsulin-dependent diabetes mellitus, NIDDM) in monotherapy and in combination with asulfonylurea, metformin, or insulin. Pioglitazone has also been used to treat non-alcoholic steatohepatitis (fatty liver), bu ...
How long does liquid amoxicillin last
... antibiotic, the solid (powder) form was mixed with the liquid. My guess is that not too long after the 10 days, the active ingredient is no. Just because the doctor prescribed amoxicillin for the last ear . Learn about Amoxil (Amoxicillin) treat, uses, dosage, side effects, drug interactions, warnin ...
... antibiotic, the solid (powder) form was mixed with the liquid. My guess is that not too long after the 10 days, the active ingredient is no. Just because the doctor prescribed amoxicillin for the last ear . Learn about Amoxil (Amoxicillin) treat, uses, dosage, side effects, drug interactions, warnin ...
Pharmacological and Medical Considerations in Hypnotic Use
... importance. Metabolism and elimination rates are thought to control the termination of drug effect; however, the distribution of a drug is also important, particularly with single doses and highly lipid-soluble agents (17). This whole process, by which the activity of a drug is terminated (distribut ...
... importance. Metabolism and elimination rates are thought to control the termination of drug effect; however, the distribution of a drug is also important, particularly with single doses and highly lipid-soluble agents (17). This whole process, by which the activity of a drug is terminated (distribut ...
Ion Exchange Resins: Drug Delivery and Therapeutic
... living materials because cell walls, cell membranes and other structures have charges. In natural waters and in wastewaters, there are often undesirable ions and some of them may be worth recovering. For example, cadmium ion is dangerous to health but is usually not present at concentrations that wo ...
... living materials because cell walls, cell membranes and other structures have charges. In natural waters and in wastewaters, there are often undesirable ions and some of them may be worth recovering. For example, cadmium ion is dangerous to health but is usually not present at concentrations that wo ...
Impact of amiodarone and cisapride on simulated human ventricular
... Both drugs show similar prolongation of the QT interval, although they present different electrophysiological properties in the single-cell as well as in tissue simulations of cardiac excitation propagation. These computer simulations help to better understand the underlying mechanisms responsible f ...
... Both drugs show similar prolongation of the QT interval, although they present different electrophysiological properties in the single-cell as well as in tissue simulations of cardiac excitation propagation. These computer simulations help to better understand the underlying mechanisms responsible f ...
The History and Implications of Testing Thalidomide on
... conditions.[5] For example, the changes in genetic makeup that occurred through evolution can result in an ancestor species giving rise to very similar, yet distinct, descendant species. For example, the line leading to chimpanzees and humans split only 5-7 million years ago but the two species reac ...
... conditions.[5] For example, the changes in genetic makeup that occurred through evolution can result in an ancestor species giving rise to very similar, yet distinct, descendant species. For example, the line leading to chimpanzees and humans split only 5-7 million years ago but the two species reac ...
Modification of Practice-dependent Plasticity in Human Motor Cortex
... requirement was that it had to be possible to evoke isolated thumb movements by TMS without overt movements of any of the other digits, wrist or arm; the other requirement was that the direction of TMSinduced thumb movements was sufficiently consistent (Bütefisch et al., 2000). Consistency was teste ...
... requirement was that it had to be possible to evoke isolated thumb movements by TMS without overt movements of any of the other digits, wrist or arm; the other requirement was that the direction of TMSinduced thumb movements was sufficiently consistent (Bütefisch et al., 2000). Consistency was teste ...
The neural basis of drug craving: an incentive
... irresistible that it almost inevitably leads to drug seeking and drug taking. It is difficult, of course, to provide an adequate definition of subjective terms, such as ‘wanting’ and craving184*“6’, but clinical experience suggests that drug craving is fundamental to addiction; it cannot be ignored. ...
... irresistible that it almost inevitably leads to drug seeking and drug taking. It is difficult, of course, to provide an adequate definition of subjective terms, such as ‘wanting’ and craving184*“6’, but clinical experience suggests that drug craving is fundamental to addiction; it cannot be ignored. ...
4427 Naltrexone/Carers.NSW
... Deciding to undergo naltrexone treatment requires careful consideration. The important thing to remember is that the patient must detox first. Naltrexone is not a euphoric alternative to heroin or other opioids. It's a drug which blocks euphoric effects and helps maintain the patient's abstinence. A ...
... Deciding to undergo naltrexone treatment requires careful consideration. The important thing to remember is that the patient must detox first. Naltrexone is not a euphoric alternative to heroin or other opioids. It's a drug which blocks euphoric effects and helps maintain the patient's abstinence. A ...
establishing similarity between multisource betahistine
... innovator product. The solubility of BHD in aqueous media over the pH range of 1-7.5 was determined. Molecular descriptors like PSA, Log P, log D, and pKa were calculated using software packages. Tablets were tested for weight and content uniformity, friability and disintegration. The in vitro relea ...
... innovator product. The solubility of BHD in aqueous media over the pH range of 1-7.5 was determined. Molecular descriptors like PSA, Log P, log D, and pKa were calculated using software packages. Tablets were tested for weight and content uniformity, friability and disintegration. The in vitro relea ...
To navigate effectively through a complex three dimensional
... mechanism (ocular and perceptual). Therefore it would seem to offer little relief for unwanted vestibular-mediated ...
... mechanism (ocular and perceptual). Therefore it would seem to offer little relief for unwanted vestibular-mediated ...
Drug design
Drug design, sometimes referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target. The drug is most commonly an organic small molecule that activates or inhibits the function of a biomolecule such as a protein, which in turn results in a therapeutic benefit to the patient. In the most basic sense, drug design involves the design of molecules that are complementary in shape and charge to the biomolecular target with which they interact and therefore will bind to it. Drug design frequently but not necessarily relies on computer modeling techniques. This type of modeling is often referred to as computer-aided drug design. Finally, drug design that relies on the knowledge of the three-dimensional structure of the biomolecular target is known as structure-based drug design. In addition to small molecules, biopharmaceuticals and especially therapeutic antibodies are an increasingly important class of drugs and computational methods for improving the affinity, selectivity, and stability of these protein-based therapeutics have also been developed.The phrase ""drug design"" is to some extent a misnomer. A more accurate term is ligand design (i.e., design of a molecule that will bind tightly to its target). Although design techniques for prediction of binding affinity are reasonably successful, there are many other properties, such as bioavailability, metabolic half-life, side effects, etc., that first must be optimized before a ligand can become a safe and efficacious drug. These other characteristics are often difficult to predict with rational design techniques. Nevertheless, due to high attrition rates, especially during clinical phases of drug development, more attention is being focused early in the drug design process on selecting candidate drugs whose physicochemical properties are predicted to result in fewer complications during development and hence more likely to lead to an approved, marketed drug. Furthermore, in vitro experiments complemented with computation methods are increasingly used in early drug discovery to select compounds with more favorable ADME (absorption, distribution, metabolism, and excretion) and toxicological profiles.