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Nervous System - APBio
Nervous System - APBio

... Production of Action Potential • 1. Resting potential: Na+ gates closed, some K+ gates open (move out) and Na-K pump active • 2. stimulus Na+ channels open, causing depolarization • 3. When threshold is met, membrane is in rising phase • 4. The Na+ channels close and K+ channels open- falling phas ...
The dorsal anterior cingulate cortex ( BA32) in autism: an
The dorsal anterior cingulate cortex ( BA32) in autism: an

... showed no significant differences between cohorts. Total mean CV of polygon areas, CV of polygon class sizes and mean point-to-point distances (between nearest neighbouring neurons) did not differ significantly between groups. At least two of the autism cases in this study showed evidence of focal n ...
Odor- and context dependent modulation of mitral cell
Odor- and context dependent modulation of mitral cell

... being hooked up to all kinds of other systems (emotional, sensory, behavioral, etc.), flexibly changing the task it’s engaged in/the computations it performs. ...
multiple choice
multiple choice

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EXAMPLE ONLINE ENTRANCE EXAMINATION Bio
EXAMPLE ONLINE ENTRANCE EXAMINATION Bio

... 1. When a mass is left on an inclined plane and the mass does not move, it is because: a. The incline is very slight. b. There is friction. c. The surfaces are made of the same material. d. Not enough time has passed. ...
The Nervous System
The Nervous System

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Ch. 2 the LGN and Striate Cortex
Ch. 2 the LGN and Striate Cortex

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Nervous and Endocrine Systems
Nervous and Endocrine Systems

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Nervous System

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Biology and Behaviour

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Chapter 2 - Biological Basis of Behavior
Chapter 2 - Biological Basis of Behavior

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Lecture 6

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action potential
action potential

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NMSI - 1 Intro to the Nervous System
NMSI - 1 Intro to the Nervous System

... • The nervous system interacts with sensory and internal body systems to coordinate responses and behaviors. ...
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Strategies for drug delivery through the blood

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Pt2Localization - MemoryAndCognition

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TECHNIQUES2001

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The Role of Natriuretic Peptides in Hearing

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The Eye

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Research Proposal: Nivedita Chatterjee
Research Proposal: Nivedita Chatterjee

... develop C.elegans strains with cameleon-labeled dopaminergic neurons/glia for dynamical calcium imaging. A further aim is to image and investigate activityinduced calcium changes in core cells of specific behavioral circuits. Optical methods provide a non-invasive way to monitor the activity of neur ...
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Theoretical Neuroscience - Neural Dynamics and Computation Lab
Theoretical Neuroscience - Neural Dynamics and Computation Lab

... biophysical units interact with each other to give rise to complex higher level cognitive phenomena remains one of the most striking conundrums in modern neuroscience. An essential component of progress on this question is the generation of testable, quantitative theories of information processing, ...
- Describe the roles of the different types of glial cells
- Describe the roles of the different types of glial cells

... dop etc) use 1-3Na and Cl- while family 2 transporters used for glutamate and aspartate use 3Na+, H+ and K+ to transport NT (very powerful). - GPCR – g protein coupled receptors are located postsynaptically and are activated based on a signal that is communicated by the release of NT. They are 7 tra ...
Neuro1
Neuro1

... 2) Myelin is a lipid-rich layer surrounding nerve cells (making a myelin sheath). It insulates axons except at their initial and terminal segments and allows faster conductions of impulses through the nerve fiber. Myelin is secreted by Schwann cells in the PNS and oligodendrocytes in the CNS. 3) All ...
Airgas template - Morgan Community College
Airgas template - Morgan Community College

... surrounding central nervous system neurons and glia. ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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