
The Behavior of Neurons
... when exciting things are happening, one has to see what is going on all around. Another fiber type of considerable behavioral interest is the space-constant group in the visual system. These fibers always look upward, even when the animal lies on its back, and therefore they represent a kind of gyro ...
... when exciting things are happening, one has to see what is going on all around. Another fiber type of considerable behavioral interest is the space-constant group in the visual system. These fibers always look upward, even when the animal lies on its back, and therefore they represent a kind of gyro ...
Unsupervised models and clustering
... In the central nervous system, the ganglion cells, which constitute the output stage of the retina, are organized according to receptive fields, sensitive to particular stimuli In the auditory system cortex, neurons and fibers are anatomically arranged in an orderly manner with respect to the acoust ...
... In the central nervous system, the ganglion cells, which constitute the output stage of the retina, are organized according to receptive fields, sensitive to particular stimuli In the auditory system cortex, neurons and fibers are anatomically arranged in an orderly manner with respect to the acoust ...
Elements of the nervous system
... • Many different types • Compartmentalized Neuronal process = = axon or dendrite ...
... • Many different types • Compartmentalized Neuronal process = = axon or dendrite ...
Probing neural circuits in the zebrafish: a suite of optical techniques
... Fig. 3. Linescans provide spatial and temporal information about the dynamics of intracellular calcium signals. With laser-scanning confocal microscopes, a single line can be scanned repetitively at 2-ms intervals. The white line illustrated crossing the cell in (A) was scanned repeatedly (nucleus i ...
... Fig. 3. Linescans provide spatial and temporal information about the dynamics of intracellular calcium signals. With laser-scanning confocal microscopes, a single line can be scanned repetitively at 2-ms intervals. The white line illustrated crossing the cell in (A) was scanned repeatedly (nucleus i ...
Cellular and Systems Neurophysiology Part 13: The Motor
... Inhibition tends to occur at the same time as excitation in motor neurons • The data below are from motor neurons that are mediating repetitive scratching behavior in a turtle • It seemed strange to most people that inhibition and excitation should occur at the same time • That is why this was publ ...
... Inhibition tends to occur at the same time as excitation in motor neurons • The data below are from motor neurons that are mediating repetitive scratching behavior in a turtle • It seemed strange to most people that inhibition and excitation should occur at the same time • That is why this was publ ...
The Cl Area of the Brainstem in Tonic and Reflex
... Cl area are local neurons, some of which can be characterized immunocytochemically as containing yaminobutyric acid (GABA),16 or being cholinergic17 or enkephalinergic.18 Neuropepu'de Y is colocalized with PNMT in some Cl neurons," while substance P, also found in the region, is only colocalized wit ...
... Cl area are local neurons, some of which can be characterized immunocytochemically as containing yaminobutyric acid (GABA),16 or being cholinergic17 or enkephalinergic.18 Neuropepu'de Y is colocalized with PNMT in some Cl neurons," while substance P, also found in the region, is only colocalized wit ...
rapid eye movement sleep deprivation induces acetylcholinesterase
... Fig. 2. Comparison of AchE activity between control and experimental animals in the preoptic area. A: Cresyl violet-stained section representing the preoptic area; B: AchE reactivity in the preoptic area in control animals. A few AchE-positive neurons were detected in this region; C: A considerable ...
... Fig. 2. Comparison of AchE activity between control and experimental animals in the preoptic area. A: Cresyl violet-stained section representing the preoptic area; B: AchE reactivity in the preoptic area in control animals. A few AchE-positive neurons were detected in this region; C: A considerable ...
The Anatomy of Language Sydney Lamb Rice University, Houston
... Nowadays multiple electrodes can be placed all over the scalp, allowing the recording of the electric activity from many different sites simultaneously Allows the construction of topographic maps of the momentary electric activity on the scalp Also permits study of the time series of these map ...
... Nowadays multiple electrodes can be placed all over the scalp, allowing the recording of the electric activity from many different sites simultaneously Allows the construction of topographic maps of the momentary electric activity on the scalp Also permits study of the time series of these map ...
Autonomic Nervous System (ANS)
... Autonomic Nervous System (ANS) Motor regulation of smooth muscle, cardiac muscle, glands & adipose tissue (“visceral effectors”) through stimulation of “visceral efferent fibers” Sympathetic (Σ) division – “fight or flight” response Parasympathetic (PΣ) division – rest & repose (“conserve & res ...
... Autonomic Nervous System (ANS) Motor regulation of smooth muscle, cardiac muscle, glands & adipose tissue (“visceral effectors”) through stimulation of “visceral efferent fibers” Sympathetic (Σ) division – “fight or flight” response Parasympathetic (PΣ) division – rest & repose (“conserve & res ...
Science in Motion
... Teachers will need to run off lab sheets. The lab file is three pages long. I recommend inserting the graph page(a separate file) as page three and running off the 4 page lab as two pages back to back. Teachers will have to provide some background information to students. They should cover the follo ...
... Teachers will need to run off lab sheets. The lab file is three pages long. I recommend inserting the graph page(a separate file) as page three and running off the 4 page lab as two pages back to back. Teachers will have to provide some background information to students. They should cover the follo ...
the pain process
... activation of NMDA receptors in dorsal horn neurons. The net effect is expanded receptor fields (pain in neighboring areas not subjected to injury, or secondary hyperalgesia) and painful responses to normally innocuous stimuli (mediated by A-beta fibers and referred to as allodynia). The combination ...
... activation of NMDA receptors in dorsal horn neurons. The net effect is expanded receptor fields (pain in neighboring areas not subjected to injury, or secondary hyperalgesia) and painful responses to normally innocuous stimuli (mediated by A-beta fibers and referred to as allodynia). The combination ...
NERVOUS SYSTEM AND REFLEXES Introduction:
... the body to the CNS are the major structures of the Peripheral Nervous System. The nerves of the PNS function to bring sensory information to the central nervous system and to carry the commands of the CNS to cells of the body. Neurons are the cells of the nervous system which conduct electrical imp ...
... the body to the CNS are the major structures of the Peripheral Nervous System. The nerves of the PNS function to bring sensory information to the central nervous system and to carry the commands of the CNS to cells of the body. Neurons are the cells of the nervous system which conduct electrical imp ...
chapter 9 the chemical senses, neural coding, and central nervous
... system, each individual receptor cell has an assortment of different ion channels that are specifically activated by a class of molecule (e.g., salt, acid, or sugar). Some receptor cells have more of a given type of ion chanel than do others. For example, one cell may have a high proportion of ion c ...
... system, each individual receptor cell has an assortment of different ion channels that are specifically activated by a class of molecule (e.g., salt, acid, or sugar). Some receptor cells have more of a given type of ion chanel than do others. For example, one cell may have a high proportion of ion c ...
nervous-system-12-1
... Function. Neurosurgeon Dr. Robert Cantu has studied the brains of many deceased athletes, including hockey and football players. He has found that these players often suffered from chronic traumatic encephalopathy (CTE), a degenerative brain disease caused by repeated blunt impact to the head. ...
... Function. Neurosurgeon Dr. Robert Cantu has studied the brains of many deceased athletes, including hockey and football players. He has found that these players often suffered from chronic traumatic encephalopathy (CTE), a degenerative brain disease caused by repeated blunt impact to the head. ...
Chapter 12: Nervous System
... Function. Neurosurgeon Dr. Robert Cantu has studied the brains of many deceased athletes, including hockey and football players. He has found that these players often suffered from chronic traumatic encephalopathy (CTE), a degenerative brain disease caused by repeated blunt impact to the head. ...
... Function. Neurosurgeon Dr. Robert Cantu has studied the brains of many deceased athletes, including hockey and football players. He has found that these players often suffered from chronic traumatic encephalopathy (CTE), a degenerative brain disease caused by repeated blunt impact to the head. ...
A real-time model of the cerebellar circuitry underlying classical
... Fig. 1. (A) Basic elements of the modeled cerebellar circuit. See text for explanation. (B) Learning curves of a circuit with varying values of persistence of the PF synapse, , over several CS-US intervals. is a multiplicative decay of the membrane potential and indirectly de"nes the time constan ...
... Fig. 1. (A) Basic elements of the modeled cerebellar circuit. See text for explanation. (B) Learning curves of a circuit with varying values of persistence of the PF synapse, , over several CS-US intervals. is a multiplicative decay of the membrane potential and indirectly de"nes the time constan ...
• The neuron is similar to other cells: •Cell body: lipid bilayer
... The CSF contains sodium (Na+), potassium (K+), chloride (Cl-), calcium (Ca++), and other ions in solution. The neuronal membrane itself (lipid bilayer) is impermable to the movement of ions. However, ions can cross the membrane by two means... ...
... The CSF contains sodium (Na+), potassium (K+), chloride (Cl-), calcium (Ca++), and other ions in solution. The neuronal membrane itself (lipid bilayer) is impermable to the movement of ions. However, ions can cross the membrane by two means... ...
Nervous System Neurons And Synapses
... a secondary tumor (i.e., it did not spread from another part of the body) because an exhaustive workup has revealed no signs of cancer elsewhere in Mr. Childs’s body. Is the brain tumor more likely to have developed from nerve tissue or from neuroglia? Why? Considering that nerve cells do not usuall ...
... a secondary tumor (i.e., it did not spread from another part of the body) because an exhaustive workup has revealed no signs of cancer elsewhere in Mr. Childs’s body. Is the brain tumor more likely to have developed from nerve tissue or from neuroglia? Why? Considering that nerve cells do not usuall ...
The Cerebellum
... – All movements, postural or voluntary, of limbs, eyes, or speech, require an appropriate pattern of activation of agonist and antagonist muscles or muscle groups. The relative timing of the bursts of activity of the agonists and antagonists determines the smoothness and coordination of the movement ...
... – All movements, postural or voluntary, of limbs, eyes, or speech, require an appropriate pattern of activation of agonist and antagonist muscles or muscle groups. The relative timing of the bursts of activity of the agonists and antagonists determines the smoothness and coordination of the movement ...
4-Nervous system I: Structure and organization
... Asiatic elephant. Science 138:1100-1103. Harwood, P. 1963. Therapeutic dosage in small and large mammals . Science 139: 684-685. ...
... Asiatic elephant. Science 138:1100-1103. Harwood, P. 1963. Therapeutic dosage in small and large mammals . Science 139: 684-685. ...
Neural Correlates of Anticipation in Cerebellum, Basal Ganglia, and
... inferior olive (IO) via the climbing fibers to the Purkinje cells, which excite the deep cerebellar nuclei (DCN) that produce the cerebellum’s output. Another input pathway goes via the mossy fibers to the granule cells and their parallel fibers that lead to other cerebellar circuits. The parallel f ...
... inferior olive (IO) via the climbing fibers to the Purkinje cells, which excite the deep cerebellar nuclei (DCN) that produce the cerebellum’s output. Another input pathway goes via the mossy fibers to the granule cells and their parallel fibers that lead to other cerebellar circuits. The parallel f ...
Lecture 02Spring10
... Electroencephalogram (EEG) An amplified recording of the electrical waves sweeping across the brain’s surface, measured by electrodes placed on the scalp. ...
... Electroencephalogram (EEG) An amplified recording of the electrical waves sweeping across the brain’s surface, measured by electrodes placed on the scalp. ...
Nervous system - Nayland College
... Nerves are thin threads of nerve cells called neurons that run through out your body. They are all bundled together and send the messages to and from your brain to all the muscles in your body. There are two different types of nerves, Sensory nerves and Motor nerves. Sensory nerves send message ...
... Nerves are thin threads of nerve cells called neurons that run through out your body. They are all bundled together and send the messages to and from your brain to all the muscles in your body. There are two different types of nerves, Sensory nerves and Motor nerves. Sensory nerves send message ...
Neuronal Loss in the Brainstem and Cerebellum
... shown in the 15 cases of this study, the reported cerebellar neuronal loss was seen in aging individuals without any underlying neurological disease that could explain the observation. The reduced neuronal number could thus be a part of the normal aging process with an accentuation in late stages of ...
... shown in the 15 cases of this study, the reported cerebellar neuronal loss was seen in aging individuals without any underlying neurological disease that could explain the observation. The reduced neuronal number could thus be a part of the normal aging process with an accentuation in late stages of ...
Sensa1on and Percep1on
... distribu&on: some we can detect easily, but not as well • Our ability to detect odours is much poorer than many other animals (e.g., dogs are 300-10,000 &mes more sensi&ve) • Differences in sensi&vity are not caused by the sensi&vity of sensory receptors, rather it is because we have far fewer ...
... distribu&on: some we can detect easily, but not as well • Our ability to detect odours is much poorer than many other animals (e.g., dogs are 300-10,000 &mes more sensi&ve) • Differences in sensi&vity are not caused by the sensi&vity of sensory receptors, rather it is because we have far fewer ...
Optogenetics

Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.