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Characterization of the apoptotic functions of the HID homolog
Characterization of the apoptotic functions of the HID homolog

... Overall, the scHID cDNA encodes a protein of 197 amino acids, while dHID cDNA encodes a protein of 410 amino acids. Sequence alignment showed share conserved regions in their Nand C-terminals as illustrated in Fig. 6. Thus, we wondered if such limited structural conservation is sufficient for the ce ...
A1982NC82200001
A1982NC82200001

... with human information processing, using computer averaging techniques to extract the tiny signals specifically related to sensorimotor processes from the random activity that predominates in the scalp-recorded electroencephalogram. Although cortical potentials elicited by external stimulation had b ...
Nervous System
Nervous System

... activities necessary to life by allowing us to receive stimuli (sensory information) from various sensory receptors and then processing them into appropriate responses made by body organs (effectors). ...
Neurons and Neural Networks: Computational Models CAMS
Neurons and Neural Networks: Computational Models CAMS

... Such non-standard currents include those that are activated in voltage ranges close to the resting potential (the membrane voltage in the absence of any input) and contribute to the generation of small-amplitude (sub-threshold) oscillations and to resonance properties (maximum impedance at a preferr ...
Bioelectric Phenomena
Bioelectric Phenomena

... found that touching the muscle with a metallic object while the specimen lay on a metal plate provided the condition that resulted in the contractions. Having heard of Franklin’s experimental proof that a flash of lightning was of the same nature as the electricity generated by electric machines, Ga ...
What is C. elegans? What are its navigational strategies?
What is C. elegans? What are its navigational strategies?

... • Behavior of the entire organism (1000 µm) • Information processing in neural circuits (10 µm) • Underlying molecular machinery – protein interactions (<0.01 µm) ...
MS Word Version
MS Word Version

... • The presence of calcium inside the cell causes the synaptic vesicles to fuse with the membrane. • Each vesicle releases a fixed amount of neurotransmitter into the synaptic cleft. • Neurotransmitter diffuses across the synaptic cleft. ...
CHARLES UNIVERSITY
CHARLES UNIVERSITY

... fibers). Detection electrode was placed in pyramidal layer of CA1 region. Single shock stimulation with supramaximal stimulus was applied and then other stimuli in determined values according to stimulation protocol. Experimental models were performed by changing the concentration of ions in the ACS ...
The Relationship Between Synchronization Among Neuronal
The Relationship Between Synchronization Among Neuronal

... empirical measurements of population activity, such as those employed by neuroimaging, are sensitive to changes in synchronization. We examined the relationship between mean population activity and synchronization using biologically plausible simulations. In this article, we focus on continuous stat ...
Chapter 12 The Nervous System
Chapter 12 The Nervous System

... y All of the information from our senses is sorted and interpreted in the cerebrum. y Controls voluntary muscles that control movement and speech y Memories are stored in this area. y Decisions are made here ...
Changing Channels
Changing Channels

... response to the neurotransmitter recognized by the grafted LBD. To create an ion channel that could respond to a novel neurotransmitter, Sternson and Looger needed to design a new LBD and synthesize a neurotransmitter that ...
• The neuron is similar to other cells: •Cell body: lipid bilayer
• The neuron is similar to other cells: •Cell body: lipid bilayer

... Neurons are surrounded by an aqueous saline solution called cerebrospinal fluid (CSF). The CSF contains sodium (Na+), potassium (K+), chloride (Cl-), calcium (Ca++), and other ions in solution. The neuronal membrane itself (lipid bilayer) is impermable to the movement of ions. However, ions can cros ...
Performance of 3xTG AD mice on the T
Performance of 3xTG AD mice on the T

... can discriminate by firing in one context but not another, or by firing in both contexts but in different locations b) it’s incidental learning ...
Chapter_Twenty_1_
Chapter_Twenty_1_

... message to a second messenger, a cyclic adenosine monophosphate (cyclic AMP), that acts within the target cell. • Neurotransmitters are synthesized in presynaptic neurons and stored there in vesicles from which they are released when needed. They travel across a synaptic cleft to receptors on adjace ...
Neurotransmitters
Neurotransmitters

... from tryptophan. Also, 5-HTP readily passes through the blood-brain barrier, and enters the central nervous system without need of a transport molecule. Note, however, that there is some evidence to suggest that a postsynaptic defect in serotonin utilization may be an important factor in depression, ...
Neuron - Schoolwires.net
Neuron - Schoolwires.net

... trigger more neurons to fire, and to fire more often, but it does not affect the action potentials strength or speed. Intensity of an action potential remains the same throughout the length of the axon. **Toilet flushing example ...
Motor Units and Motor Neuron Disease
Motor Units and Motor Neuron Disease

... The transgenic mouse model called G93A-SOD1 was used in the first paper as a model for human ALS. The SOD1 gene contains a mutation at position 93 where Glycine is replaced by Alanine (hence G93A). Yim et. Al (1996) found that the ALS symptoms observed in G93A transgenic mice were not caused by the ...
Hybrots - Computing Science and Mathematics
Hybrots - Computing Science and Mathematics

... bridge this chasm, to allow top-down behavior-based approaches to go down to the cell and molecular level, and to allow the bottom-up reductionism of cellular neurobiology to connect to the cognitive level. We aim to explore the terra incognita of network-level neuronal and glial dynamics, at a vari ...
Chapter 28 - Montville.net
Chapter 28 - Montville.net

... – Excite the receiving cell – Inhibit the receiving cell’s activity by decreasing its ability to develop action potentials ...
13-1 CHAPTER 13 SYNAPSES The nervous system consists of
13-1 CHAPTER 13 SYNAPSES The nervous system consists of

... transmitter substance in one neuron, but serves a different purpose in another one. Table 13-1 contains a list of some of the substances that have been suggested as chemical transmitter substances, their presumed actions2, locations of highest concentration within the central nervous system, modes o ...
High-speed CCD movie camera with random pixel selection,
High-speed CCD movie camera with random pixel selection,

... neurons, each with hundreds or thousands of connections (synapses) to other neurons. There are major gaps in our understanding of how a structure that fits inside a skull and consumes only about 100 watts can have huge memory capacity and very rapid recall. This amazing organ effortlessly provides c ...
Nervous System
Nervous System

... • Composed of nerve cells called neurons, which are specialized to carry nerve impulses. • Nervous system has two major divisions: (the division is arbitrary; the two systems work together and are connected to one another). The two systems are: 1. Central Nervous System: (CNS) - includes spinal cord ...
AG-VT - 02.424 06.1 Skeleton and Vital Organs
AG-VT - 02.424 06.1 Skeleton and Vital Organs

... Glial cells make up 90 percent of the brain's cells. Glial cells are nerve cells that don't carry nerve impulses. The various glial (meaning "glue") cells perform many important functions, including: digestion of parts of dead neurons, manufacturing myelin for neurons, providing physical and nutriti ...
The Lateral Geniculate Nucleus of the Thalamus (A model for all
The Lateral Geniculate Nucleus of the Thalamus (A model for all

... Iontropic receptors (inputs) CANNOT cause mode switches: mGLUR from cortex or mACH from parabrachial region cause switch from burst to tonic & GABAb from brainstem reticular formation and local interneurons – opposite. ...
Biological and Artificial Neurons Lecture Outline Biological Neurons
Biological and Artificial Neurons Lecture Outline Biological Neurons

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Electrophysiology



Electrophysiology (from Greek ἥλεκτρον, ēlektron, ""amber"" [see the etymology of ""electron""]; φύσις, physis, ""nature, origin""; and -λογία, -logia) is the study of the electrical properties of biological cells and tissues. It involves measurements of voltage change or electric current on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and particularly action potential activity. Recordings of large-scale electric signals from the nervous system such as electroencephalography, may also be referred to as electrophysiological recordings.
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