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of the smooth muscles
of the smooth muscles

... It is characterized by the instability of its membrane potential and by the fact that it shows continuous, irregular contractions that are independent of its nerve supply. This maintained state of partial contraction is called tonus or tone. There is no true "resting" value for the membrane potentia ...
Slide 1
Slide 1

Chemical Communication PowerPoint
Chemical Communication PowerPoint

... where neurotransmitters can bind. ...
Neural Analysis
Neural Analysis

... of gratings in which luminance varied sinusoidally along one axis. Such a stimulus is a visual analogue of a pure tone (see chapter 7 and Fig. 7.1) and its frequency is usually expressed as the number of cycles per degree of visual angle. It initially recommended itself because it was the mathematic ...
Chronic multiunit recordings in behaving animals: advantages and
Chronic multiunit recordings in behaving animals: advantages and

... Abstract: By simultaneous recording from neural responses at many different loci at the same time, we can understand the interaction between neurons, and thereby gain insight into the network properties of neural processing, instead of the functioning of individual neurons. Here we will discuss a me ...
Spatial cognition and neuro-mimetic navigation: a model of
Spatial cognition and neuro-mimetic navigation: a model of

... dentate gyrus, SC subiculum, NA nucleus accumbens, VTA ventral tegmental area, PP perforant path, FX fornix. The hippocampus proper consists of the CA3-CA1 areas. The hippocampal formation consists of the hippocampus proper, the dentate gyrus, the entorhinal cortex, and the subicular complex (Redish ...
McConnell SK, Kaznowski CE (1991)
McConnell SK, Kaznowski CE (1991)

... cells obtained from a litter of E29 ferret fetuses; points with error bars represent the averages of two samples obtained from each of two litters (error bars, ±SD). (A) The number of labeled cells in S-phase decreases with time as cells complete DNA replication and move into G2. (B) The fraction of ...
Accurate identification of single-nucleotide
Accurate identification of single-nucleotide

... set obtained by multiple annealing and looping–based amplification cycles (MALBAC)7, SCcaller reported more than two times higher overlapping somatic-SNV calls in all kindred cells than did Monovar, MuTect or VarScan (Fig. 2f and Supplementary Note). Notably, the fraction of overlapping calls in thi ...
Microscopy of myelination - Formatex Research Center
Microscopy of myelination - Formatex Research Center

... topographic image or recognize specific locations of interest, particularly in any system composed of more than one type of cell or material. Pairing high resolution techniques with light microscopy can go some way to addressing this problem, allowing the user to assess a larger field of view before ...
Neurons and Glia
Neurons and Glia

... The Nissl stain, however, does not tell the whole story. A Nissl-stainedneuron looks Iike little more than a lump of protoplasm containing a nucleus. Neurons are much more than that, but how much more was not recognized until the publication of the work of Italian histologist Camillo Golgi (Figure 2 ...
Stem cell biology and drug discovery | BMC Biology | Full Text
Stem cell biology and drug discovery | BMC Biology | Full Text

... there is evidence that pathways that regulate embryonic development and, hence, act in large part on tissue stem and progenitor cells are also disrupted in adult disease [6,7]. For example, the hedgehog signaling pathway, of vital importance in nervous system development, is hyper­activated either b ...
Structure of the Nervous System Functional Classes of Neurons
Structure of the Nervous System Functional Classes of Neurons

... • These peripheral nerves can contain nerve fibers that are the  axons of efferent neurons, afferent neurons, or both.  • All the spinal nerves contain both afferent and efferent fibers, whereas some of the cranial nerves contain only afferent  fibers or only efferent fibers. • Efferent neurons carr ...
binding, internalization, and retrograde transport of `251
binding, internalization, and retrograde transport of `251

... tion of NGF and potentially an interaction, either directly contained a partially purified preparation of 7 S NGF (Varon et al., 1967) added at a concentration of 1 pg/ml. or indirectly, with the genome (Yankner and Shooter, 1979; Marchisio et al., 1980, 1981). Alternatively, the sole Typically, the ...
lec12
lec12

... • If we use topographic maps for different properties, we can assume that properties at the same location belong to the same thing. ...
Neuronal Loss in the Brainstem and Cerebellum
Neuronal Loss in the Brainstem and Cerebellum

... EUROPATHOLOGY is, as the name implies, aimed at describing the morphological changes induced in the CNS in disease. Pathological processes occurring late in life may be difficult to distinguish from those of normal aging. It has been shown that different parts of the human brain are affected differe ...
Slide ()
Slide ()

... nucleus prepositus hypoglossi on both sides of the brain stem. These neurons receive velocity signals from excitatory burst neurons and integrate this Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available velocity ...
NERVOUS SYSTEM1.ppt [Recovered]
NERVOUS SYSTEM1.ppt [Recovered]

... membrane of the neurons. The presence of ion channels needed to be studied experimentally and this technique provided the technology. Using a suction electrode (glass micropipette in top right) to suck onto a piece of membrane, which by gentle pulling breaks away but, remains on the end of the pipet ...
Specificity of Synaptic Connections II (i.e. Target Selection by Axons)
Specificity of Synaptic Connections II (i.e. Target Selection by Axons)

...  Eph/ephrin signaling establishes topography of the nasal-temporal axis of the retinotectal projection: - Knockout of the genes for the ephrins or Eph resulted in loss of normal topography in the retinal projection. - Misexpression of ephrin-A2 in high concentration across the entire tectum prevent ...
Retinal diseases
Retinal diseases

... cannot be influenced from outside, once it is implanted. This may be an advantage or a disadvantage, depending on the quality of the surgical operation. It is easier to integrate a higher number of electrode sites onto the subretinal device. Current designs will have a number of 2000 electrode sites ...
Application of MEMS in Optobionics: Artificial Silicon Retina
Application of MEMS in Optobionics: Artificial Silicon Retina

... cannot be influenced from outside, once it is implanted. This may be an advantage or a disadvantage, depending on the quality of the surgical operation. It is easier to integrate a higher number of electrode sites onto the subretinal device. Current designs will have a number of 2000 electrode sites ...
wood ant (formica lugubris zett.)
wood ant (formica lugubris zett.)

... or windows of varying size through which neurons make direct contact with each other. These somasomatic junctions arc approximately the size of vertebrate synapses. This type of junction between neurons is very unusual and has been found only in one other case by electron microscopists. Hopsu and Ar ...
FIAT 8 - UCLA Statistics
FIAT 8 - UCLA Statistics

... humans to hear, provided it is done early. • Experiments on kittens than are born deaf. • Implants given at age 3-4 months. • Several months of training, kittens behaviour showed they “hear” sounds normally. (Brain activity confirms this). ...
Substrates for Cell Culture
Substrates for Cell Culture

... - Poly-lysine is a polymer of the basic – and therefore positively charged at pH7 - amino acid lysine. - Poly-lysine can be used to coat plastic or glass surfaces to enhance the binding of cells. This is a ‘non-specific’ effect, in that the negative charge of cell membranes is electrostatically attr ...
ELECTROENCEPHALOGRAM_(EEG).
ELECTROENCEPHALOGRAM_(EEG).

... • 20-min or longer sampling of brain activity • Written out or recorded directly on magnetic tape or digitally by computer • Disc electrodes are applied according to 10-20 system ...
Special Senses
Special Senses

... chemicals present in the environment • Olfactory and gustatory (taste) impulses travel not only to the ...
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Electrophysiology



Electrophysiology (from Greek ἥλεκτρον, ēlektron, ""amber"" [see the etymology of ""electron""]; φύσις, physis, ""nature, origin""; and -λογία, -logia) is the study of the electrical properties of biological cells and tissues. It involves measurements of voltage change or electric current on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and particularly action potential activity. Recordings of large-scale electric signals from the nervous system such as electroencephalography, may also be referred to as electrophysiological recordings.
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