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Synaptic Integration of Olfactory Information in Mouse Anterior
Synaptic Integration of Olfactory Information in Mouse Anterior

... For extracellular recordings, an excitatory response was defined as an elevation in firing rate during the 2 s odor presentation exceeding 2 SDs of the baseline firing rate, measured during the 4 s prestimulus interval, and significantly larger than the firing rate change induced by mineral oil (Stu ...
Three-Dimensional Reconstruction and Stereoscopic Display of
Three-Dimensional Reconstruction and Stereoscopic Display of

... The present set-up was developed for our particular research on the fly' s brain (Hengstenberg et al. 1982). It is, however, generally applicable. Other magnifications of microscope or projection yield various trade-offs between field size and resolution. The figures in Table 1 emphasize that the re ...
Myotatic Reflex
Myotatic Reflex

... cell body acts like a sphere (charges/ions distribute evenly over a spherical surface). ...
theta oscillation in the hippocampus
theta oscillation in the hippocampus

... biocytin for intracellular labeling. In some experiments the recording pipette also contained 10 mM of the lidocaine derivative QX 314 (Sigma, St. Louis, MO). The intracellular electrode was inserted ,1.0 mm posterior to the extracellular electrodes. In vivo electrode impedances varied from 60 to 10 ...
Anatomy Review
Anatomy Review

... -4917. (Page 4.) The neuron synapsing on the soma inhibits the cell and prevents it from generating an _______ _________. a. action potential b. synaptic potential 18. (Page 5.) Label the diagrams on page 5. 19. (Page 5.) In the brain, a variety of synapses have evolved to serve complex transmissio ...
An alarm pheromone increases the responsivity of
An alarm pheromone increases the responsivity of

... firing rate of basal amygdaline neurons. However, it is unknown whether 2-heptanone modifies the responsivity of medial amygdalinehippocampal connection. Therefore, we placed a group (n=10) of Wistar rats in a plexiglass cage impregnated with 2-heptanone. Rats from control group (n=10) were introduc ...
English  - SciELO México
English - SciELO México

... firing rate of basal amygdaline neurons. However, it is unknown whether 2-heptanone modifies the responsivity of medial amygdalinehippocampal connection. Therefore, we placed a group (n=10) of Wistar rats in a plexiglass cage impregnated with 2-heptanone. Rats from control group (n=10) were introduc ...
Cholinergic modulation of synaptic properties of cortical layer VI
Cholinergic modulation of synaptic properties of cortical layer VI

Opposite rheological properties of neuronal microcompartments
Opposite rheological properties of neuronal microcompartments

... Engineering, School of Engineering and Applied Sciences, Harvard University, 29 Oxford Street, Cambridge, MA 02138, USA. ...
Cutaneous mechanoreceptors
Cutaneous mechanoreceptors

Malformations - Hospital Universitari de Bellvitge
Malformations - Hospital Universitari de Bellvitge

... Malformations of the nervous system result from different causes including genetic and environmental factors that may act at different target stages of embryonic or fetal development Genetic factors are usually the consequence of point mutations, and malformations are inherited as autosomal dominant ...
Parthenogenetic dopamine neurons from primate embryonic stem
Parthenogenetic dopamine neurons from primate embryonic stem

... Some of these TH+ neurons produce DA but have different axonal connectivity and physiology from those in the midbrain substantia nigra (SN) that are lost in Parkinson’s disease. Parthenogenesis has attracted attention as an alternative way to derive pluripotent stem cell lines that does not involve ...
35-2 The Nervous System
35-2 The Nervous System

Axons break in animals lacking β-spectrin
Axons break in animals lacking β-spectrin

... The proximal end has initiated a new growth cone (open arrowhead). At 48 h, the secondary growth has reached the dorsal cord, albeit by an aberrant posterior route (open arrowheads). (The new dorsal and posterior neuron is DVB [asterisks], which arises postembryonically and sends an axon ventrally t ...
The basic Hebb rule
The basic Hebb rule

... Non-Hebbian forms of synaptic plasticity • They modify synaptic strengths solely on the basis of pre- or postsynaptic firing, are likely to play important roles in homeostatic, developmental, and learning processes • Homeostatic plasticity -It allows neurons to sense how active they are and to adju ...
Sequential Development of Electrical and Chemical Synaptic
Sequential Development of Electrical and Chemical Synaptic

... HLX; Osram Sylvania, Danvers, MA) in standard housing (HAL 100; Zeiss), powered by a low-ripple power supply (JQE 15-12M; Kepco, Flushing, NY). For all voltage-sensitive dye imaging, we acquired images only at the coumarin emission wavelength. The filter set consisted of a 405 ⫾ 15 nm bandpass excit ...
The Nervous System
The Nervous System

... – All communication between the CNS and the rest of the body occurs over the PNS • Sensory information detected outside the nervous system by receptors is transmitted by the afferent division of the PNS to sites in the CNS • The CNS then processes this information and sends motor commands via the ef ...
Distributed Processing of Sensory Information in
Distributed Processing of Sensory Information in

... For simplicity, the excitor of lateral muscleswasnot recorded. The L cell was not monitored because,with a combined dorsal and ventral field of innervation, its effects are only partially consistent with dorsal and ventral bending. As a first step in analyzing the processingof sensoryinformation in ...
Rapid changes in protein synthesis and cell size in the cochlear
Rapid changes in protein synthesis and cell size in the cochlear

... by using tetrodotoxin (TTX). Born and Rubel ('88)injected TTX into the perilymph of young chicks and studied morphological and physiological parameters in the NM. The changes elicited by TTX exposure are similar to those elicited by cochlea ablation, except that the effects of TTX injection are temp ...
Culture of primary rat hippocampal neurons
Culture of primary rat hippocampal neurons

... motors move), and the mechanism of cargo attachment are all susceptible to damage resulting in transport breakdown and cell damage or death (De Vos et al. 2008). Species such as sodium azide (Selvatici et al. 2009) (NaN3 ) and peroxynitrite (Szabo et al. 2007)(ONOO− ) have been shown to damage cells ...
1 The Brain and Behavior
1 The Brain and Behavior

... Two Opposing Views Have Been Advanced on the Relationship Between Brain and Behavior Our current views about nerve cells, the brain, and behavior have emerged over the last century from a convergence of five experimental traditions: anatomy, embryology, physiology, pharmacology, and psychology. Befo ...
Properties and Functional Role of Voltage
Properties and Functional Role of Voltage

... We used outside-out patches for characterizing potassium currents because they allow recording of relatively large currents and also facilitate the application of different drugs to study the pharmacological profile of the channels. A potential disadvantage is that properties of channels might chang ...
Exam II Questions / Answers
Exam II Questions / Answers

... plasma membrane is the site of electrical signaling Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings ...
35-2 The Nervous System
35-2 The Nervous System

... An action potential begins when a. sodium ions flow into the neuron. b. potassium ions flow into the neuron. c. sodium and potassium ions flow into the neuron. d. sodium and potassium ions flow out of the neuron. ...
Cell Surface Molecules Containing IV
Cell Surface Molecules Containing IV

... identity of the stained neurons known, since the labeling included cell bodies and dendrites, but not axons. As a first step towards defining molecular and structural relationships for cortical local circuit neurons, we have studied the morphology of cells exhibiting surface GalNac-containing molecu ...
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Electrophysiology



Electrophysiology (from Greek ἥλεκτρον, ēlektron, ""amber"" [see the etymology of ""electron""]; φύσις, physis, ""nature, origin""; and -λογία, -logia) is the study of the electrical properties of biological cells and tissues. It involves measurements of voltage change or electric current on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and particularly action potential activity. Recordings of large-scale electric signals from the nervous system such as electroencephalography, may also be referred to as electrophysiological recordings.
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