Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau
... brain extracts from rTg4510 mice, which overexpress human mutant P301L tau, by centrifugation either at 3,000, 10,000, 50,000 or 150,000g, and applied the supernatant to mouse primary cortical neurons. The uptake of tau was assessed by immunofluorescence labelling of intracellular human tau. After 24 ...
... brain extracts from rTg4510 mice, which overexpress human mutant P301L tau, by centrifugation either at 3,000, 10,000, 50,000 or 150,000g, and applied the supernatant to mouse primary cortical neurons. The uptake of tau was assessed by immunofluorescence labelling of intracellular human tau. After 24 ...
Auditory Imagery: Empirical Findings
... the final note were not influenced by whether participants heard all the notes leading up to the final note or imaged some of the notes, but judgments of the timing of the final note were severely impaired when participants imaged some of the notes leading up to the final note. Janata and Paroo sugg ...
... the final note were not influenced by whether participants heard all the notes leading up to the final note or imaged some of the notes, but judgments of the timing of the final note were severely impaired when participants imaged some of the notes leading up to the final note. Janata and Paroo sugg ...
PDF - Bentham Open
... associated with greater fear conditioned SCRs compared to participants with low trait anxiety [34]. Further, our prior work has demonstrated that unconditioned fMRI signal responses from several brain regions fluctuate with trait anxiety level [17]. Specifically, trait anxiety varied with dlPFC, dmP ...
... associated with greater fear conditioned SCRs compared to participants with low trait anxiety [34]. Further, our prior work has demonstrated that unconditioned fMRI signal responses from several brain regions fluctuate with trait anxiety level [17]. Specifically, trait anxiety varied with dlPFC, dmP ...
REM Sleep - Test Page
... REM sleep control and especially to the peptide hypocretin. Finally, I speculate about the functions of REM sleep. REM sleep was discovered by Aserinsky and Kleitman in 1953. 1 They found that it was characterized by the periodic recurrence of rapid eye movements, linked to a dramatic reduction in t ...
... REM sleep control and especially to the peptide hypocretin. Finally, I speculate about the functions of REM sleep. REM sleep was discovered by Aserinsky and Kleitman in 1953. 1 They found that it was characterized by the periodic recurrence of rapid eye movements, linked to a dramatic reduction in t ...
State transitions between wake and sleep, and within the
... clear consensus among sleep EEG workers some of whom go along with Dement and Kleitman7 and Rechtschaffen and Kales8 who define sleep onset in stage 1 based on criteria of alpha reduction. The most frequently used definition, however, situates it at the first appearance of sleep spindles or K-comple ...
... clear consensus among sleep EEG workers some of whom go along with Dement and Kleitman7 and Rechtschaffen and Kales8 who define sleep onset in stage 1 based on criteria of alpha reduction. The most frequently used definition, however, situates it at the first appearance of sleep spindles or K-comple ...
elsevier second proof - Michigan State University
... Although there are theoretical reasons for envi- p0065 sioning that the receptors in a chemosensory system should differ in their breadth of tuning (Hildebrand and Shepherd, 1997), it is not clear that vertebrates possess any narrowly tuned receptor neurons. To illustrate this point, we will briefly ...
... Although there are theoretical reasons for envi- p0065 sioning that the receptors in a chemosensory system should differ in their breadth of tuning (Hildebrand and Shepherd, 1997), it is not clear that vertebrates possess any narrowly tuned receptor neurons. To illustrate this point, we will briefly ...
Highwire Regulates Guidance of Sister Axons in the
... powerful model system to investigate such axonal behaviors (Heisenberg, 1998; Davis, 2005; Fahrbach, 2006). The MB is composed of three neuronal subtypes—␥, ␣⬘/⬘, and ␣/ neurons—that can be distinguished by their birth order and the location of their axonal projections (Lee et al., 1999). Cell bod ...
... powerful model system to investigate such axonal behaviors (Heisenberg, 1998; Davis, 2005; Fahrbach, 2006). The MB is composed of three neuronal subtypes—␥, ␣⬘/⬘, and ␣/ neurons—that can be distinguished by their birth order and the location of their axonal projections (Lee et al., 1999). Cell bod ...
Longtin - noise in neural systems
... actually make more sense of it than we can, such as in temporal and spatial coincidences of inputs. Hence, one person’s noise may be another person’s information: It depends ultimately on the phenomena you are trying to understand. This explains in part why there has been such a thrust in the last d ...
... actually make more sense of it than we can, such as in temporal and spatial coincidences of inputs. Hence, one person’s noise may be another person’s information: It depends ultimately on the phenomena you are trying to understand. This explains in part why there has been such a thrust in the last d ...
Potential switch from eupnea to fictive gasping after blockade of
... peak phrenic activity could only be compared for a subset of the preparations after some experimental perturbations. In these procedures, requiring extended times for completion, it was necessary to reposition the recording electrode periodically. Hence, changes in values of peak phrenic activity co ...
... peak phrenic activity could only be compared for a subset of the preparations after some experimental perturbations. In these procedures, requiring extended times for completion, it was necessary to reposition the recording electrode periodically. Hence, changes in values of peak phrenic activity co ...
Chapter 14 PowerPoint - IHMC Public Cmaps (2)
... Swelling and dispersal of the Nissl substance Cell increases in metabolic activity, protein synthesis, and mitochondrial activity New terminal sprouts project from the proximal segment Process limited to myelinated axons ...
... Swelling and dispersal of the Nissl substance Cell increases in metabolic activity, protein synthesis, and mitochondrial activity New terminal sprouts project from the proximal segment Process limited to myelinated axons ...
Effects of Reversible Inactivation of the Primate Mesencephalic
... Predictions about the specific oculomotor deficits, which may occur after inactivation of brain stem structures, are easier to understand by reference to these models. Shifts in the input to either model, that is a more distant orbital position (EP model), or larger eye displacement (ED model), woul ...
... Predictions about the specific oculomotor deficits, which may occur after inactivation of brain stem structures, are easier to understand by reference to these models. Shifts in the input to either model, that is a more distant orbital position (EP model), or larger eye displacement (ED model), woul ...
Relative Contributions of Specific Activity Histories and
... to represent a major mechanism for modifying the functional properties of neuronal networks. Indeed, overwhelming experimental evidence supports the idea that synaptic properties are affected by the history of their activation. What is less established and often ignored is the "flip side" of synapti ...
... to represent a major mechanism for modifying the functional properties of neuronal networks. Indeed, overwhelming experimental evidence supports the idea that synaptic properties are affected by the history of their activation. What is less established and often ignored is the "flip side" of synapti ...
Neural representation of olfactory mixtures in the honeybee
... B), using a color code and a glomerular map layout similar to that introduced by Galizia et al. (1999a). Response magnitude (number of active glomeruli) We asked how the magnitude of AL activity changes with added mixture components. We thus evaluated the number of activated glomeruli with increasin ...
... B), using a color code and a glomerular map layout similar to that introduced by Galizia et al. (1999a). Response magnitude (number of active glomeruli) We asked how the magnitude of AL activity changes with added mixture components. We thus evaluated the number of activated glomeruli with increasin ...
Histamine in the Nervous System
... Histamine-containing somata and fibers are widespread in arthropod brains, with the most intense labeling in the retinal photoreceptors and in the first optic ganglion, where the short visual fibers contact the monopolar neurons (507, 576, 711). Histamine is released from arthropod photoreceptors an ...
... Histamine-containing somata and fibers are widespread in arthropod brains, with the most intense labeling in the retinal photoreceptors and in the first optic ganglion, where the short visual fibers contact the monopolar neurons (507, 576, 711). Histamine is released from arthropod photoreceptors an ...
Interaction of the Frontal Eye Field and Superior Colliculus for
... with direct electrical stimulation of the FEF. To test the role of the SC in conveying information to the brain stem, we inactivated the SC, thereby removing the circuit through the SC to the brain stem, and leaving only the direct FEF– brain stem pathway. If the contributions of the direct pathway ...
... with direct electrical stimulation of the FEF. To test the role of the SC in conveying information to the brain stem, we inactivated the SC, thereby removing the circuit through the SC to the brain stem, and leaving only the direct FEF– brain stem pathway. If the contributions of the direct pathway ...
2009 McGraw-Hill Higher Education Site Map Any use is subject to
... Any use is subject to the Terms of Use and Privacy Notice. McGraw-Hill Higher Education is one of the many fine business of The McGraw-Hill ...
... Any use is subject to the Terms of Use and Privacy Notice. McGraw-Hill Higher Education is one of the many fine business of The McGraw-Hill ...
Kaczkurkin_umn_0130E_14221
... the CR as significantly more “nocive” or unpleasant than non-anxious individuals. This arousal is suggested to be substantial enough to serve as a replacement for the US which not only results in resistance to extinction but has been suggested to “incubate” or enhance the CR over time. There are cur ...
... the CR as significantly more “nocive” or unpleasant than non-anxious individuals. This arousal is suggested to be substantial enough to serve as a replacement for the US which not only results in resistance to extinction but has been suggested to “incubate” or enhance the CR over time. There are cur ...
Seven principles in the regulation of adult neurogenesis
... hierarchy matters little. Individual mechanisms of regulation might fill one or a few papers, but will always raise questions about their integration into the bigger picture. Obviously, regulation does not only occur by means of gene transcription. There are numerous posttranscriptional and post-tran ...
... hierarchy matters little. Individual mechanisms of regulation might fill one or a few papers, but will always raise questions about their integration into the bigger picture. Obviously, regulation does not only occur by means of gene transcription. There are numerous posttranscriptional and post-tran ...
Hox Genes: Choreographers in Neural Development, Architects of
... Hox genes function in multiple neuronal classes to shape synaptic specificity during development, suggesting a broader role in circuit assembly. This Review highlights the functions and mechanisms of Hox gene networks and their multifaceted roles during neuronal specification and connectivity. Intro ...
... Hox genes function in multiple neuronal classes to shape synaptic specificity during development, suggesting a broader role in circuit assembly. This Review highlights the functions and mechanisms of Hox gene networks and their multifaceted roles during neuronal specification and connectivity. Intro ...
SOP #11 Acoustic Startle and Pre
... The startle response is comprised of a constellation of reflexes elicited by sudden, relatively intense stimuli. It offers many advantages as a behavioral measure of central nervous system (CNS) activity and can be measured in numerous species, including humans, when elicited by acoustic (noise burs ...
... The startle response is comprised of a constellation of reflexes elicited by sudden, relatively intense stimuli. It offers many advantages as a behavioral measure of central nervous system (CNS) activity and can be measured in numerous species, including humans, when elicited by acoustic (noise burs ...
neuroanatomy - University of Toledo
... This selection of the art of Dr. Frank H. Netter on neuroanatomy and neurophysiology is drawn from the Atlas of Human Anatomy and Netter’s Atlas of Human Physiology. Viewing these pictures again prompts reflection on Dr. Netter’s work and his roles as physician and artist. Frank H. Netter was born i ...
... This selection of the art of Dr. Frank H. Netter on neuroanatomy and neurophysiology is drawn from the Atlas of Human Anatomy and Netter’s Atlas of Human Physiology. Viewing these pictures again prompts reflection on Dr. Netter’s work and his roles as physician and artist. Frank H. Netter was born i ...
D27 - Viktor`s Notes for the Neurosurgery Resident
... - dominant rhythm in awake state at rest (with mind wandering and eyes closed). most marked in PARIETO-OCCIPITAL area. regular 8-12 Hz, 20-100 μV waves; normal frequency is age dependent (if frequency is less than normal for age group – it is abnormality!) amplitude often waxes and wanes over ...
... - dominant rhythm in awake state at rest (with mind wandering and eyes closed). most marked in PARIETO-OCCIPITAL area. regular 8-12 Hz, 20-100 μV waves; normal frequency is age dependent (if frequency is less than normal for age group – it is abnormality!) amplitude often waxes and wanes over ...
Test Bank 1
... 32. Neurons that collect messages from sense organs and carry those messages to the spinal cord or the brain are called ________ neurons. a. association b. afferent Correct: Afferent neuron is another term for sensory neuron, which is responsible for taking messages from the sensory organs to the ce ...
... 32. Neurons that collect messages from sense organs and carry those messages to the spinal cord or the brain are called ________ neurons. a. association b. afferent Correct: Afferent neuron is another term for sensory neuron, which is responsible for taking messages from the sensory organs to the ce ...
Rapid Translocation of Zn 2+ from Nerve Terminals
... years that endogenous Zn2⫹ may act as a neurotransmitter or neuromodulator at excitatory synapses. It has been surmised for some time that Zn2⫹ is released from synaptic terminals by a variety of stimuli. This conclusion was based on the localization of vesicular Zn2⫹ in synaptic terminals and on in ...
... years that endogenous Zn2⫹ may act as a neurotransmitter or neuromodulator at excitatory synapses. It has been surmised for some time that Zn2⫹ is released from synaptic terminals by a variety of stimuli. This conclusion was based on the localization of vesicular Zn2⫹ in synaptic terminals and on in ...
Modality-Based Organization of Ascending Somatosensory Axons in
... cuneate fasciculus (Cu) that formed above thoracic segment 6 (T6), which innervate the GN, CN, and ECN in the medulla; and (3) the corticospinal tract (CST) at the most ventral area of the dorsal column. Primary somatosensory afferents from S6 –T7 and T6 –C1 DRGs travel in the Gr and Cu, respectivel ...
... cuneate fasciculus (Cu) that formed above thoracic segment 6 (T6), which innervate the GN, CN, and ECN in the medulla; and (3) the corticospinal tract (CST) at the most ventral area of the dorsal column. Primary somatosensory afferents from S6 –T7 and T6 –C1 DRGs travel in the Gr and Cu, respectivel ...