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...  To think, feel or act without a body would be like running without legs. -We are bio-psycho-social systems. To understand our behavior, we need to study how biological, psychological and social systems interact. ...
PID *****2515 1.Why is it difficult to understand olfactory neural
PID *****2515 1.Why is it difficult to understand olfactory neural

... amplification step in olfactory transduction, and is enabled by a chloride transporter that  maintains a high Cl­ concentration in the cilia. This enables short odorant dwell times.  Expeditious signal termination is required to ensure faithful temporal representation of odor  stimuli, and it is ach ...
The Nervous System
The Nervous System

... Monitors changes/events occurring in and outside the body. Such changes are known as stimuli and the cells that monitor them are receptors. ...
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... dorsal root ganglia (DRG), accounting for the largest fraction of the resting potassium conductance in these neurons. Recent evidence supports the role of TRESK in setting up sensory neuron excitability under pathological conditions. (Tulleuda et al., 2011, Mol Pain). The exaggerated glycolytic meta ...
Lecture3
Lecture3

Mirror Neurons
Mirror Neurons

... Uniview Worldwide Ltd warrants that it is fully entitled to enter into this Agreement and to grant the rights referred to in this Agreement. This Agreement shall be governed by English law, and the English courts shall be the courts of ...
Psychology 210
Psychology 210

chapter 11-nerve tissue
chapter 11-nerve tissue

... sheaths. This can lead to abnormal sensations, muscle weakness and decreased motor function. 2) MS is characterized by frequent attacks, each causing ...
to find the lecture notes for lecture 6 nervous tissue click here
to find the lecture notes for lecture 6 nervous tissue click here

... – Opening of chloride channels (inward) or potassium channels (outward) ...
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Pain - WordPress.com

... The archispinothalamic tract is a multisynaptic diffuse tract or pathway. The first-order nociceptive neurons make synaptic connections in Rexed layer II (substantiagelatinosa) and ascend to laminae IV to VII. From lamina IV to VII, fibers ascend and descend in the spinal cord via the ...
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Vestibulospinal Tract - Viktor`s Notes for the Neurosurgery Resident

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Theoretical Neuroscience: From Single Neuron to Network Dynamics

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Nerve Cell Signaling - Mr. Moore`s Web Page

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excitatory neurotransmitter

... Glutamate is excitatory, so it stimulates the neurons in a neural pathway to fire. This is very important in memory and learning. High levels of glutamate are found within the hippocampus in the brain. The hippocampus is where the majority of long term memories are consolidated in preparation for st ...
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... Does the cortex have some general properties or does its structure depend on the function: perceptive, motor, associative? There is a functional specialization of the cortex, observable differences in various areas, from this comes the division into Brodmann’s fields. The general scheme is retained: ...
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action potentials - Zanichelli online per la scuola

... Membrane potential is the electrical charge difference across the membrane. Resting potential is the steady state membrane potential of a neuron. Voltage (electric potential difference): force that causes charged particles to move between two points. The resting potential of an axon is –60 to –70 mi ...
Unit 8 - Perry Local Schools
Unit 8 - Perry Local Schools

... Monoamines (modified amino acids)  Widely distributed in the brain  Emotional behavior  Circadian rhythm  Some motor neurons of the ANS  EX: Epinephrine, norepinephrine, dopamine, serotonin, histamine Unmodified amino acids  Ex: Glutamate, aspartate, GABA, glycine ...
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Is Diabetic Nerve Pain Caused by Dysregulated

... Pain-sensing sensory neurons, or nociceptors, can be sensitized (become hyperexcitable) by various mechanisms in response to the pathological conditions or peripheral tissue injury associated with diabetes. Multiple pathogenic mechanisms, such as the formation of intracellular advanced glycation end ...
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Pre-Bötzinger complex



The pre-Bötzinger complex (preBötC) is a cluster of interneurons in the ventrolateral medulla of the brainstem. This complex has been proven to be essential for the generation of respiratory rhythm in mammals. The exact mechanism of the rhythm generation and transmission to motor nuclei remains controversial and the topic of much present research.Several synthetic compounds have been shown to act on neurons specific to the preBötC, most being selective agonists or antagonists to receptor subtypes on neurons in the vicinity. Since many of these neurons express GABA, glutamate, serotonin and adenosine receptors, chemicals custom tailored to bind at these sites are most effective at altering respiratory rhythm.Adenosine modulates the preBötC output via activation of the A1 and A2A receptor subtypes. An adenosine A1 receptor agonist has been shown to depress preBötC rhythmogenesis independent of the neurotransmitters GABA and glycine in ""in vitro"" preparations from 0-7 day old mice. Another synthetic drug specific to the adenosine A2A receptor subtype is CGS-21680 that has been shown to cause apneas in 14-21 day old rat pups in vivo. For this reason, it has been used as a model to study pathological conditions such as apnea of prematurity and SIDS in neonatal infants.
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