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M.learning.hccs.edu
M.learning.hccs.edu

... E) critical to reflexes. 11. The sum of the electrical and chemical forces acting on an ion is known as its ________. 12. The ________ ...
Answers to Questions — neurons
Answers to Questions — neurons

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Norepinephrine as a neurotransmitter

... a. Opioid receptors were discovered to bind with drugs such as opium and morphine, resulting in pain relief. b. Endogenous opioids are polypeptides produced by the brain and pituitary gland; includes enkephalin, β-endorphin, and dynorphin c. Opioids also produce euphoria so they may mediate reward p ...
BOX 2.1 THE NEURON DOCTRINE The cell theory, which states
BOX 2.1 THE NEURON DOCTRINE The cell theory, which states

... The cell theory, which states that all organisms are composed of individual cells, was developed around the middle of the nineteenth century by Mattias Schleiden and Theodor Schwann. However, this unitary vision of the cellular nature of life was not immediately applied to the nervous system, as mos ...
Note: This hypothesis is mainly concerned with peripheral neurons
Note: This hypothesis is mainly concerned with peripheral neurons

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“The Physiology of Excitable Cells”

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Chapter 16
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conductance versus current-based integrate-and - Neuro

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Cells of the Nervous System

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Function of Neurotransmitters

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Division of Brain Sciences Department of Medicine PhD studentship

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Aldwin de Guzman Abstract - UF Center for Undergraduate Research

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Bridget Lecture 2 Notes The Neurons o Functional classes (CNS

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Sending Signals Notes

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L7- Physiology of Co..

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Neuron Unit 3A

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Pre-Bötzinger complex



The pre-Bötzinger complex (preBötC) is a cluster of interneurons in the ventrolateral medulla of the brainstem. This complex has been proven to be essential for the generation of respiratory rhythm in mammals. The exact mechanism of the rhythm generation and transmission to motor nuclei remains controversial and the topic of much present research.Several synthetic compounds have been shown to act on neurons specific to the preBötC, most being selective agonists or antagonists to receptor subtypes on neurons in the vicinity. Since many of these neurons express GABA, glutamate, serotonin and adenosine receptors, chemicals custom tailored to bind at these sites are most effective at altering respiratory rhythm.Adenosine modulates the preBötC output via activation of the A1 and A2A receptor subtypes. An adenosine A1 receptor agonist has been shown to depress preBötC rhythmogenesis independent of the neurotransmitters GABA and glycine in ""in vitro"" preparations from 0-7 day old mice. Another synthetic drug specific to the adenosine A2A receptor subtype is CGS-21680 that has been shown to cause apneas in 14-21 day old rat pups in vivo. For this reason, it has been used as a model to study pathological conditions such as apnea of prematurity and SIDS in neonatal infants.
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