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psych mod 8 terms - Riverside School District
psych mod 8 terms - Riverside School District

... Cocaine- which comes from the leaves of the coca plant, has physiological and behavioral effects very similar to amphetamine. Like amphetamine, cocaine produces increased heart rate and blood pressure, enhanced mood, alertness, increased activity, decreased appetite, and diminished fatigue. With hig ...
lecture10-TOLERANCE
lecture10-TOLERANCE

Do antidepressants really work?
Do antidepressants really work?

...  Our findings seem to be at odds with clinical practice  Normal clinical practice patients are not routinely prescribed with placebos  Placebos and drugs are not given to patients randomly  Doctors and patients are not double blinded  reported success comes from the changes a patient expects ra ...
Exelon - DavisPlus
Exelon - DavisPlus

... cure the disease. Therapeutic Effects: Decreased dementia (temporary) associated with Alzheimer’s disease and Parkinson’s disease. Enhanced cognitive ability. ...
Medications and Alzheimer`s Disease
Medications and Alzheimer`s Disease

... Busprone (Buspar) is an anti-anxiety agent which does not cause sedation or dependency. It’s been used to treat anxiety disorders, but its high safety profile is making it attractive for AD patients. Benadryl is an antihistamine used as a sedative which has high anticholinergic effects (dry mouth, c ...
Rapid Sequence Intubation
Rapid Sequence Intubation

... • Minimize vagal effects, bradycardia, secretions – Infants and children < 8 yrs may develop profound bradycardia during intubation ...
poster
poster

... Early clinical development (ECD) trial represents the transition between the preclinical and the clinical full development. The main objective of our trials is to determine the maximum tolerated dose of a new compound. Because the data generated in these studies, are often the “first in human (FIH)” ...
pegaptanib - Harvard Pilgrim Health Care
pegaptanib - Harvard Pilgrim Health Care

... ocular adverse events related to the injection procedure in most patients. Pegaptanib did not accumulate in plasma after multiple doses; systemic exposures were similar after the first, fourth, and eighth doses. Evaluation of blood pressure and urine protein, both of which are known to be affected b ...
Treating hot flushes: An alternative to hormonal replacement therapy
Treating hot flushes: An alternative to hormonal replacement therapy

... and Aropax® (paroxetine), also available in generic brands. The most commonly prescribed SSRIs for hot flushes at the Royal Women’s Hospital are: • Fluoxetine available in 20mg capsules or tablets • Citalopram available in 20mg tablets • Paroxetine available in 20mg tablets SSRIs are a class of m ...
presentation
presentation

... • Any investigation or study that uses human subjects and – is intended to test the clinical effects of an investigational agent and/or – to identify any adverse reactions to an investigational agent to assess the safety and efficacy A Subject is………….A participant in research either as a recipient o ...
Acute Change in Mental Status/Delirium
Acute Change in Mental Status/Delirium

... Ask for autopsy from family in all inpatient deaths. If necessary chaplains can help explain different religion’s precepts and prohibitions. Autopsy is important source of medical education. It is estimated that about 20% of autopsies reveal new information on presumed diagnosis or cause of death. A ...
Exploring the clinical applications of a multi‑infusion model
Exploring the clinical applications of a multi‑infusion model

... administration of drugs by infusion is often associated with adverse drug events [1,2]. There are many reasons for this, such as the complex pharmacokinetics and pharmacodynamics (PK/PD) of critical drugs. Physiological models incorporating PK/PD-parameters are therefore used to determine the regime ...
Product Monograph - Takeda Canada Inc.
Product Monograph - Takeda Canada Inc.

... available in patients with severe hepatic impairment. An increased exposure in patients with severe hepatic impairment is expected and these patients should therefore be monitored for potential systemic effects. Immune Patients who are on drugs that suppress the immune system are more susceptible to ...
Case 3 continued
Case 3 continued

... • Hypothesis: glyburide has active metabolite that accumulates in renally-impaired patients while glipizide does not. – Glyburide has (less potent) active metabolite that is renally eliminated – Glipizide has (less potent) active metabolite that is renally eliminated ...
What is Health Psychology?
What is Health Psychology?

... – Results: • All patients given placebo • Pain killer  reduction • No pain killer  no reduction ...
COMFORTIS®-Cats
COMFORTIS®-Cats

... laboratory studies. No dogs were withdrawn from the field studies due to treatment-related adverse reactions. In a dose tolerance study, COMFORTIS was administered orally to adult Beagle dogs at average doses of up to 100 mg/kg once daily for 10 consecutive days (16.7 times the maximum recommended m ...
What is polypharmacy
What is polypharmacy

... There was a typographical error on page 1 of NPS News 11 on Depression. The juxtaposition of the text made it appear that moclobemide, nefazodone and venlafaxine are SSRIs. We would like to clarify that this is not the case. ...
Preventing Anticoagulation Errors with Clinical Dashboards
Preventing Anticoagulation Errors with Clinical Dashboards

... • Oral factor Xa inihibitor • FDA approved for ortho prophylaxis – 10 mg daily ...
Developing medicines for the future and why it is challenging
Developing medicines for the future and why it is challenging

... • Concentrate preventative or therapeutic interventions on those most likely to benefit thus optimising patient benefit, sparing side effects and expense of treating those unlikely to benefit. • Involves development and use of companion diagnostics to achieve the best outcomes for the patient ...
Checklist of Information to be Included When Reporting a Clinical
Checklist of Information to be Included When Reporting a Clinical

... 6 Eligibility criteria of study participants is described 7 Information about ethical approval of the study and subjects’ consent is provided. 8 Co-administration (or lack thereof) of study drug(s) with other potentially interacting drugs or food within this study is described. 9 Drug preparation an ...
ind
ind

... patient population, condition or disease (if applicable), dose, route, and duration of substance administration, and endpoint measures. 6. A copy of the protocol 7. A brief explanation of why you consider the substance(s) safe for administration to human subjects under the conditions of the study (a ...
Barbiturates - Anesthesia Slides, Presentations and Publications by
Barbiturates - Anesthesia Slides, Presentations and Publications by

... Tidal volume depression than rate ...
Product Information – Australia Chemmart Bisoprolol Tablets Page 1
Product Information – Australia Chemmart Bisoprolol Tablets Page 1

... completed about 48 hours before anaesthesia. Abrupt withdrawal: The cessation of therapy with bisoprolol should not be done abruptly unless clearly indicated. Care should be taken if β-blockers have to be discontinued abruptly in patients, particularly in patients with coronary artery disease. Sever ...


... In each study, CDP840 was well-tolerated and no serious adverse events were reported. In particular none of the subjects in any of the three studies experienced nausea or vomiting. Of a total of 23 nonserious adverse events, six occurred during placebo periods and 17 during treatment with CDP840. Wh ...
Opthea Reports Positive Phase 1/2A Clinical Results for OPT
Opthea Reports Positive Phase 1/2A Clinical Results for OPT

... 1/2A trial can be found at: www.clinicaltrials.gov, Clinical trial identifier: NCT02543229. About Opthea Limited Opthea (ASX:OPT) is a biologics drug developer focusing on ophthalmic disease therapies. It controls exclusive worldwide rights to a significant intellectual property portfolio around Vas ...
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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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