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One pill for all heart problems - Royal College of Surgeons in Ireland
One pill for all heart problems - Royal College of Surgeons in Ireland

... As many as 28 Indian institutes, including AIIMS, PGIChandigarh and George Institute for Global Health-India worked together as part of the study, planned by London's Imperial College. The formulation for the drug was done by Dr Reddy's Laboratories. "Most patients with high BP require multiple drug ...
to use it with caution, in a dose never exceeding... Few clinical reports on selected case series have been made
to use it with caution, in a dose never exceeding... Few clinical reports on selected case series have been made

... two studies. Further attention is required to define the efficacy/safety profile of a dosage of linezolid 800 mg q.d. in the treatment of ‘‘complicated’’ MDR/XDR-TB cases [9]. Outcomes: a complete comparison on outcomes is not possible, as the time to sputum smear and culture conversion was not calc ...
File
File

... metabolites for elimination and to prevent drug accumulation. The first-pass effect is the extent to which a drug is metabolized by the liver before reaching systemic circulation. ...
Prescribing Information
Prescribing Information

... asymptomatic non-life-threatening ventricular arrhythmias who had a myocardial infarction more than 6 days but less than 2 years previously, an increased rate of death or reversed cardiac arrest rate (7.7%; 56/730) was seen in subjects treated with encainide or flecainide (Class IC antiarrhythmics) ...
PACKAGE INSERT TEMPLATE FOR PARACETAMOL
PACKAGE INSERT TEMPLATE FOR PARACETAMOL

... Adverse Effects / Undesirable Effects Adverse effects of paracetamol are rare and usually mild, although haematological reactions have been reported. Skin rashes and other hypersensitivity reactions occur occasionally. Overdose and Treatment Symptoms: Toxic symptoms include vomiting, abdominal pain, ...
Hydrofluoroalkane-134a Beclomethasone
Hydrofluoroalkane-134a Beclomethasone

... using a mini-Wright peak flow meter (Clement Clarke; Columbus, OH), before use of b-agonist or study medication. Daytime symptoms of wheezing, shortness of breath, chest tightness, and cough were rated on a scale of 0 to 5 (0 5 not present, 5 5 so severe that the patient could not attend work or car ...
Pertussis Treatment - Antibiotic Recommendations
Pertussis Treatment - Antibiotic Recommendations

... cannot tolerate macrolides, or who are infected with a rare macrolide-resistant strain of B. pertussis. Source: MMWR 2005; 54:RR–14 (Note: Recommendations in the 2012 Red Book vary slightly from the table above.) ...


... The result is better gastric acid stability, higher bioavailability, a longer half-life, and a broader spectrum of antimicrobial activity than erythromycin. This allows a decrease in both the frequency and overall dosage and fewer adverse effects in the gastrointestinal tract.3-5 ...
Patient Criteria for Starting Treatment
Patient Criteria for Starting Treatment

... Funding Request for Group Prior Approval for RITUXIMAB for the Treatment of REFRACTORY VASCULITIS or SYSTEMIC LUPUS ERYTHEMATOSUS NHS Hertfordshire will not normally fund any treatment where the patient does not meet the agreed criteria as outlined in this Group Prior Approval. If the consultant wis ...
Manegment of parkinson’s disease.
Manegment of parkinson’s disease.

... • prevalence in PD patients ranges between 33 and 60% • male > female this male predominance are not yet known • treated with clonazepam in small doses (0.25–1 mg) dopaminergic agents (DA , levodopa) donepezil Melatonin was reported to be effective at doses of 3–12 mg. ...
Nozinan (methotrimeprazine)
Nozinan (methotrimeprazine)

... Rare cases of priapism have been reported with antipsychotic use, such as Nozinan. This adverse reaction, as with other psychotropic drugs, did not appear to be dose-dependent and did not correlate with the duration of treatment. The most likely mechanism of action of priapism is a relative decrease ...
ProSom (estazolam)
ProSom (estazolam)

... of insomnia. Similar to other benzodiazepines, ProSom has anxiolytic effects (i.e., relieves anxiety), but it is seldom prescribed for this use. It has an intermediate duration of action (i.e., half-life around 16 hours) and no active metabolite. For some patients, a single bedtime dose may lead to ...
Pharmacogenomics and Personalized Medicine
Pharmacogenomics and Personalized Medicine

...  ADRs are typically the 5th leading cause of death in the United States and are one of the leading, preventable public health issues today.  In terms of total health care dollars, ADRs cost the U.S. health care system between $1.5 and $5.4 billion per year. ...
INTRODUCTION TO PHARMACOLOGY
INTRODUCTION TO PHARMACOLOGY

... New scientific insights—in some cases, inferred from novel mechanisms of action– have been essential to this progress, together with controlled clinical trials, in particular, randomized, double-blind trials In parallel (especially in recent years) has been the promotion of “alternative” and “comple ...
Cefixim - The IBN SINA Pharmaceutical Industry Ltd.
Cefixim - The IBN SINA Pharmaceutical Industry Ltd.

... Bone & joint infection and also most suitable for switch therapy from parenteral therapy. DOSAGE AND ADMINISTRATION: With Cefixim the usual course of treatment is 7 days. This may be continued up to 14 days. Adults & Children over 10 years old: The recommended adult dosage is 200-400 mg daily accord ...
Sub-Therapeutic Doses in the Treatment of Depression: The
Sub-Therapeutic Doses in the Treatment of Depression: The

... by prescribing sub-therapeutic doses either unknowingly or out of over-cautiousness. This is supported, at least in part, by the survey finding that psychiatrists admit to using sub-therapeutic doses significantly more than other types of physicians (Raz, et al., 2011). Establishing a clear consensu ...
NCATS Mission - Collaborative Drug Discovery
NCATS Mission - Collaborative Drug Discovery

... AZD2423 is a potent orally bioavailable non-competitive, negative allosteric modulator of the CCR2 chemokine receptor. CCR2 is a receptor for monocyte chemoattractant protein MCP-1 (CCL2) and the closely related proteins MCP-2 (CCL8), MCP-3 (CCL7), and MCP-4 (CCL13). Human CCR2 exists as two forms, ...
Q1. Viruses and bacteria cause diseases in humans. (a) Draw a ring
Q1. Viruses and bacteria cause diseases in humans. (a) Draw a ring

... Half the mice were given a daily dose of caffeine in their drinking water. The dose was equivalent to the amount of caffeine in six cups of coffee for a human. The other mice were given ordinary water. After two months, the caffeine-drinking mice did better in memory tests than the mice drinking ord ...
Dr Qamariya - Obgyncluboman.com
Dr Qamariya - Obgyncluboman.com

...  Incomplete miscarriage (4-12 wks GA), (clinical finding : open os & vaginal bleeding):  600 microgram as a single dose, orally  Induction of miscarriage up to 24 wks: ...
HIV Infection in Solid Organ Transplant Patients
HIV Infection in Solid Organ Transplant Patients

... lopinavir/ritonavir (Kaletra), nelfinavir (RTV), saquinavir ...
Special precautions
Special precautions

... ➢ others like: tonsillitis, streptococcus infections, ear infection, warts, and nose and throat infections. ...
ACORDA THERAPEUTICS INC (Form: 8-K
ACORDA THERAPEUTICS INC (Form: 8-K

... M.D., Ph.D., Acorda’s Senior Vice President of Research and Development. “We plan to advance our clinical program based on these data; the next study will include patients experiencing acute relapses. The combined results of these two studies will inform subsequent trials, which we anticipate will e ...
Takeda and Lundbeck Announce FDA Approval
Takeda and Lundbeck Announce FDA Approval

... placebo-controlled studies (incidence ≥5 percent and at least twice the rate of placebo) were nausea, constipation and vomiting. Overall, 5 to 8 percent of the patients who received Brintellix 5 to 20 mg/day in short-term trials discontinued treatment due to an adverse reaction, the most common bein ...
Naloxone (Narcan) Drug Information Classification Opioid
Naloxone (Narcan) Drug Information Classification Opioid

... It is not known whether naloxone is excreted into human breast milk. Consideration of the risks and benefits of administration should be applied. Initial dose of 0.4mg followed by a repeat 0.4mg dose every 2 minutes prn. Each THN Kit contains two 0.4mg/mL vials. Intramuscular (IM) or Subcutaneous (S ...
Threshold Pharmaceuticals Initiates Phase 1 Clinical Trial
Threshold Pharmaceuticals Initiates Phase 1 Clinical Trial

... Threshold Pharmaceuticals Initiates Phase 1 Clinical Trial Evaluating TH-302 in Patients With Solid Tumors REDWOOD CITY, Calif., July 26, 2007 /PRNewswire-FirstCall via COMTEX News Network/ -Threshold Pharmaceuticals, Inc. (Nasdaq: THLD), today announced that it has initiated a Phase 1 clinical tria ...
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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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