Basic Neuroanatomy
... Inhibits reuptake of serotonin, norepinephrine, and (to some extent) dopamine Used as an anti-obesity drug with modest results Rapidly metabolized in the liver to active metabolites that are responsible for its pharmacologic action (prodrug) Metabolites reach a peak at 3-4 hours in plasma Half-life ...
... Inhibits reuptake of serotonin, norepinephrine, and (to some extent) dopamine Used as an anti-obesity drug with modest results Rapidly metabolized in the liver to active metabolites that are responsible for its pharmacologic action (prodrug) Metabolites reach a peak at 3-4 hours in plasma Half-life ...
Q17 Classify the calcium channel blockers and
... improve cardiac function by improving ischaemia. In patients with CCF can make LV function worse (because it reduces myocardial contractility). Contraindicated in patients with WPW as may cause VT/VF ...
... improve cardiac function by improving ischaemia. In patients with CCF can make LV function worse (because it reduces myocardial contractility). Contraindicated in patients with WPW as may cause VT/VF ...
Absorption, distribution, metabolism and excretion
... enter the body (by mouth or injection or…) - must cross barriers to entry (skin, gut wall, alviolar membrane…..) are distributed by the blood to the site of action - intra- or extracellular - cross barriers to distribution (capillaries, cell wall….) distribution affects concentration at site of acti ...
... enter the body (by mouth or injection or…) - must cross barriers to entry (skin, gut wall, alviolar membrane…..) are distributed by the blood to the site of action - intra- or extracellular - cross barriers to distribution (capillaries, cell wall….) distribution affects concentration at site of acti ...
Prevention and monitoring of the side effects of chronic
... decreased comparing to those without adverse events (7). In the other study, elderly people had decreased corticoid clearance (8): for that reason it is necessary to lower GCS doses in this group of patients. Comorbidities also affects the metabolism of GCS. The most important include: Hyperthyroidi ...
... decreased comparing to those without adverse events (7). In the other study, elderly people had decreased corticoid clearance (8): for that reason it is necessary to lower GCS doses in this group of patients. Comorbidities also affects the metabolism of GCS. The most important include: Hyperthyroidi ...
Package Insert
... Pharmacokinetics: Following an oral dose of 14C-finasteride in humans, the bioavailability is approximately 80 % (relative to an intravenous reference dose). This is not affected by food. Finasteride reaches maximum plasma concentrations within approximately 2 hours. Absorption is complete after 6 – ...
... Pharmacokinetics: Following an oral dose of 14C-finasteride in humans, the bioavailability is approximately 80 % (relative to an intravenous reference dose). This is not affected by food. Finasteride reaches maximum plasma concentrations within approximately 2 hours. Absorption is complete after 6 – ...
Sample Chapter
... Kidney disease or drugs that reduce renal clearance, such as nonsteroidal antiinflammatory drugs (NSAIDs), may increase serum concentration of drugs that are excreted by the kidneys (such as lithium). Older adults are more sensitive to psychotropics because of their decreased intracellular water, pr ...
... Kidney disease or drugs that reduce renal clearance, such as nonsteroidal antiinflammatory drugs (NSAIDs), may increase serum concentration of drugs that are excreted by the kidneys (such as lithium). Older adults are more sensitive to psychotropics because of their decreased intracellular water, pr ...
Sympathomimetcs & Parasympatholytics
... Aerosol dose: .25-.7ml Q4 Side effects: tachycardia, headache, hypertension, N&V, agitation/tremors, drying of mucosa and secretions ...
... Aerosol dose: .25-.7ml Q4 Side effects: tachycardia, headache, hypertension, N&V, agitation/tremors, drying of mucosa and secretions ...
A General Framework for Model-Based Drug
... Consider other design constraints (cross-over, titration, etc.) ...
... Consider other design constraints (cross-over, titration, etc.) ...
product monograph
... disorders, as drugs of this class are known to lower seizure threshold. Tardive Dyskinesia: Tardive dyskinesia is a syndrome consisting of potentially irreversible, involuntary, dyskinetic movement that may develop in patients receiving treatment with antipsychotic drugs (see ADVERSE REACTIONS). The ...
... disorders, as drugs of this class are known to lower seizure threshold. Tardive Dyskinesia: Tardive dyskinesia is a syndrome consisting of potentially irreversible, involuntary, dyskinetic movement that may develop in patients receiving treatment with antipsychotic drugs (see ADVERSE REACTIONS). The ...
LAVOISIER FUROSEMIDE 20 mg/2 ml, injectable solution (IM-IV)
... Diuretics (for oral administration) remain however, a key element in the treatment of oedemas resulting from cardiac, hepatic and renal insufficiency, occurring in pregnant women. ...
... Diuretics (for oral administration) remain however, a key element in the treatment of oedemas resulting from cardiac, hepatic and renal insufficiency, occurring in pregnant women. ...
Antibiotics
... against common gram positive pathogens Useful in treating soft tissue infections Cannot use if patient is allergic to penicillin Tx: 250, 500 & 875 (generic) or 1000 mg (branded only) tablet q 12 hrs x 7-10 days Can be taken with meals ...
... against common gram positive pathogens Useful in treating soft tissue infections Cannot use if patient is allergic to penicillin Tx: 250, 500 & 875 (generic) or 1000 mg (branded only) tablet q 12 hrs x 7-10 days Can be taken with meals ...
FORADIL CAPSULES FOR INHALATION (formoterol) 12 microgram
... For regular maintenance therapy, 1 to 2 inhalation capsules (equivalent to 12 to 24 micrograms formoterol) twice daily. Foradil should only be prescribed as an add-on to an inhaled corticosteroid (ICS). The maximum recommended maintenance dose is 48 micrograms per day. If required, an additional 1 t ...
... For regular maintenance therapy, 1 to 2 inhalation capsules (equivalent to 12 to 24 micrograms formoterol) twice daily. Foradil should only be prescribed as an add-on to an inhaled corticosteroid (ICS). The maximum recommended maintenance dose is 48 micrograms per day. If required, an additional 1 t ...
Pegin insert
... (benzyl alcohol) which may be found in this product can infrequently cause serious problems (sometimes death) if given in large amounts (more than 100 milligrams per kilogram daily) to an infant during the first months of life (neonatal period). The risk is also greater with low birth weight infants ...
... (benzyl alcohol) which may be found in this product can infrequently cause serious problems (sometimes death) if given in large amounts (more than 100 milligrams per kilogram daily) to an infant during the first months of life (neonatal period). The risk is also greater with low birth weight infants ...
The Rational Use of Antibiotics
... drugs The way in which a physician and other professionals use an antibiotic can affect the response of future patients Responsibility to society Antibiotic resistance can spread from ...
... drugs The way in which a physician and other professionals use an antibiotic can affect the response of future patients Responsibility to society Antibiotic resistance can spread from ...
DARAPRIM® (pyrimethamine) 25 mg tablets Rx Only
... discontinue the drug according to the response of the patient. Folinic acid (leucovorin) should be administered in a dosage of 5 to 15 mg daily (orally, IV, or IM) until normal hematopoiesis is restored. Data in 2 humans indicate that pyrimethamine may be carcinogenic; a 51-year-old female who devel ...
... discontinue the drug according to the response of the patient. Folinic acid (leucovorin) should be administered in a dosage of 5 to 15 mg daily (orally, IV, or IM) until normal hematopoiesis is restored. Data in 2 humans indicate that pyrimethamine may be carcinogenic; a 51-year-old female who devel ...
A Year in Review: Top New Drugs for 2010
... 2. Risk of major bleeding was significantly less. 3. Risk of hemorrhagic stroke was less. 4. All cause mortality was reduced. ...
... 2. Risk of major bleeding was significantly less. 3. Risk of hemorrhagic stroke was less. 4. All cause mortality was reduced. ...
AusPAR: Ivacaftor - Therapeutic Goods Administration
... The exposure of ivacaftor increased approximately 2-4 fold when given with food containing fat. ...
... The exposure of ivacaftor increased approximately 2-4 fold when given with food containing fat. ...
ppt
... & bicarbonate secretion. 2- Enhances mucosal blood flow. 3- Acts on parietal cells, reducing histamine-stimulated cAMP production and causing modest acid inhibition. 4- Stimulates intestinal electrolyte & fluid secretion, 5- Increase intestinal motility 6- Uterine contractions. ...
... & bicarbonate secretion. 2- Enhances mucosal blood flow. 3- Acts on parietal cells, reducing histamine-stimulated cAMP production and causing modest acid inhibition. 4- Stimulates intestinal electrolyte & fluid secretion, 5- Increase intestinal motility 6- Uterine contractions. ...
The clinical efficacy of inhaled ... ) in the treatment of asthma ®
... not an easy task and conflicting results and conclusions have been reached in different trials with new therapies. This review attempts to assess, in an easily understood format, the results of a complete programme of work on an asthma drug (nedocromil sodium) and reduce the risk of decisions being ...
... not an easy task and conflicting results and conclusions have been reached in different trials with new therapies. This review attempts to assess, in an easily understood format, the results of a complete programme of work on an asthma drug (nedocromil sodium) and reduce the risk of decisions being ...
Bilastine
Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.